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Volumn 69, Issue , 2013, Pages 10-21

Synthesis, hypoglycemic activity and molecular modeling studies of pyrazole-3-carbohydrazides designed by a CoMFA model

Author keywords

1,5 Diaryl pyrazole; Cannabinoid receptor 1 antagonism; Homology modeling; Hypoglycemic activity; Molecular docking; Molecular dynamics

Indexed keywords

1 (2,4 DICHLOROPHENYL) 4 METHYL N (1 PIPERIDINYL) 5 [4 (TRIFLUOROMETHYL)PHENYL] 1H PYRAZOLE 3 CARBOXAMIDE; 1 (2,4 DICHLOROPHENYL) N (1 PIPERIDINYL) 4 METHYL 5 PHENYL 1H PYRAZOLE 3 CARBOXAMIDE; 1 (2,4 DIFLUOROPHENYL) 5 (4 FLUOROPHENYL) 4 METHYL N (1 PIPERIDINYL) 1H PYRAZOLE 3 CARBOXAMIDE; 1 (3 CHLORO 4 FLUOROPHENYL) 5 (4 CHLOROPHENYL) 4 METHYL N (1 PIPERIDINYL) 1H PYRAZOLE 3 CARBOXAMIDE; 1 (3 CHLORO 4 FLUOROPHENYL) 5 (4 FLUOROPHENYL) 4 METHYL N (1 PIPERIDINYL) 1H PYRAZOLE 3 CARBOXAMIDE; 1 (7 CHLOROQUINOLIN 4 YL) 5 (4 FLUOROPHENYL) 4 METHYL N (1 PIPERIDINYL) 1H PYRAZOLE 3 CARBOXAMIDE; 4 METHYL 1,5 DIPHENYL N (1 PIPERIDINYL) 1H PYRAZOLE 3 CARBOXAMIDE; 5 (4 BROMOPHENYL) 4 METHYL N (1 PIPERIDINYL) 1 [4 (TRIFLUOROMETHYL)PHENYL] 1H PYRAZOLE 3 CARBOXAMIDE; 5 (4 CHLOROPHENYL) 1 (3,4 DICHLOROPHENYL) 4 METHYL N (1 PIPERIDINYL) 1H PYRAZOLE 3 CARBOXAMIDE; 5 (4 CHLOROPHENYL) 1 (7 CHLOROQUINOLIN 4 YL) 4 METHYL N 1 PIPERIDNYL) 1H PYRAZOLE 3 CARBOXAMIDE; 5 (4 CHLOROPHENYL) 4 METHYL N (1 PIPERIDINYL) 1 [4 (TRIFLUOROMETHYL)PHENYL] 1H PYRAZOLE 3 CARBOXAMIDE; 5 (4 CHLOROPHENYL)1 (2,4 DICHLOROPHENYL) 4 METHYL N (1 PIPERIDINYL) 1H PYRAZOLE 3 CARBOXAMIDE; ANTIDIABETIC AGENT; ANTIOBESITY AGENT; CANNABINOID 1 RECEPTOR; GLIBENCLAMIDE; GLUCOSE; LITHIUM SALT; PYRAZOLE DERIVATIVE; RIMONABANT; UNCLASSIFIED DRUG;

EID: 84884487695     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2013.07.054     Document Type: Article
Times cited : (41)

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