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Volumn 305, Issue 6, 2013, Pages

Advanced glycation end products promote hepatosteatosis by interfering with SCAP-SREBP pathway in fructose-drinking mice

Author keywords

AGEs; Carboxymethyl lysine; Fructose; Glucose; Hepatosteatosis; Soft drink; SREBP; Triglyceride synthesis

Indexed keywords

ADVANCED GLYCATION END PRODUCT; FRUCTOSE; LYSINE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRIACYLGLYCEROL;

EID: 84884410878     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00450.2012     Document Type: Article
Times cited : (56)

References (52)
  • 1
    • 0026731769 scopus 로고
    • Failure of common glycation assays to detect glycation by fructose
    • Ahmed N, Furth AJ. Failure of common glycation assays to detect glycation by fructose. Clin Chem 38: 1301-1303, 1992.
    • (1992) Clin Chem , vol.38 , pp. 1301-1303
    • Ahmed, N.1    Furth, A.J.2
  • 3
    • 27844525883 scopus 로고    scopus 로고
    • Up-regulation of advanced glycated products receptors in the brain of diabetic rats is prevented by antioxidant treatment
    • Aragno M, Mastrocola R, Medana C, Restivo F, Catalano MG, Pons N, Danni O, Boccuzzi G. Up-regulation of advanced glycated products receptors in the brain of diabetic rats is prevented by antioxidant treatment. Endocrinology 146: 5561-5567, 2005.
    • (2005) Endocrinology , vol.146 , pp. 5561-5567
    • Aragno, M.1    Mastrocola, R.2    Medana, C.3    Restivo, F.4    Catalano, M.G.5    Pons, N.6    Danni, O.7    Boccuzzi, G.8
  • 6
    • 77649094326 scopus 로고    scopus 로고
    • Soft drink consumption and obesity: It is all about fructose
    • Bray GA. Soft drink consumption and obesity: it is all about fructose. Curr Opin Lipidol 21: 51-57, 2010.
    • (2010) Curr Opin Lipidol , vol.21 , pp. 51-57
    • Bray, G.A.1
  • 7
    • 38649116056 scopus 로고    scopus 로고
    • Selective versus total insulin resistance
    • Brown MS, Goldstein JL. Selective versus total insulin resistance. Cell Metab 7: 95-96, 2008.
    • (2008) Cell Metab , vol.7 , pp. 95-96
    • Brown, M.S.1    Goldstein, J.L.2
  • 8
    • 80052388637 scopus 로고    scopus 로고
    • Increased very low density lipoprotein (VLDL) secretion, hepatic steatosis, and insulin resistance
    • Choi SH, Ginsberg HN. Increased very low density lipoprotein (VLDL) secretion, hepatic steatosis, and insulin resistance. Trends Endocrinol Metab 22: 353-363, 2011.
    • (2011) Trends Endocrinol Metab , vol.22 , pp. 353-363
    • Choi, S.H.1    Ginsberg, H.N.2
  • 10
    • 39849102805 scopus 로고    scopus 로고
    • Regulation of sterol synthesis in eukaryotes
    • Espenshade PJ, Hughes AL. Regulation of sterol synthesis in eukaryotes. Annu Rev Genet 41: 401-427, 2007.
    • (2007) Annu Rev Genet , vol.41 , pp. 401-427
    • Espenshade, P.J.1    Hughes, A.L.2
  • 11
    • 77957302090 scopus 로고    scopus 로고
    • Hepatic steatosis: A role for de novo lipogenesis and the transcription factor SREBP-1c
    • Ferré P, Foufelle F. Hepatic steatosis: a role for de novo lipogenesis and the transcription factor SREBP-1c. Diabetes Obes Metab 2: 83-92, 2010.
    • (2010) Diabetes Obes Metab , vol.2 , pp. 83-92
    • Ferré, P.1    Foufelle, F.2
  • 13
    • 0041823228 scopus 로고    scopus 로고
    • Impact of metabolic control and serum lipids on the concentration of advanced glycation end products in the serum of children and adolescents with type 1 diabetes, as determined by fluorescence spectroscopy and N-(carboxymethyl)lysine ELISA
    • Galler A, Müller G, Schinzel R, Kratzsch J, Kiess W, Münch G. Impact of metabolic control and serum lipids on the concentration of advanced glycation end products in the serum of children and adolescents with type 1 diabetes, as determined by fluorescence spectroscopy and N-(carboxymethyl)lysine ELISA. Diabetes Care 26: 2609-2615, 2003.
    • (2003) Diabetes Care , vol.26 , pp. 2609-2615
    • Galler, A.1    Müller, G.2    Schinzel, R.3    Kratzsch, J.4    Kiess, W.5    Münch, G.6
  • 14
    • 77049125246 scopus 로고    scopus 로고
    • Soluble receptor for advanced glycation end products in physiological and pathological pregnancy
    • Germanová A, Koucký M, Hájek Z, Parízek A, Zima T, Kalousová M. Soluble receptor for advanced glycation end products in physiological and pathological pregnancy. Clin Biochem 43: 442-446, 2010.
    • (2010) Clin Biochem , vol.43 , pp. 442-446
    • Germanová, A.1    Koucký, M.2    Hájek, Z.3    Parízek, A.4    Zima, T.5    Kalousová, M.6
  • 15
    • 78349297565 scopus 로고    scopus 로고
    • Oxidative stress and diabetic complications
    • Giacco F, Brownlee M. Oxidative stress and diabetic complications. Circ Res 107: 1058-1070, 2010.
    • (2010) Circ Res , vol.107 , pp. 1058-1070
    • Giacco, F.1    Brownlee, M.2
  • 16
    • 33746920337 scopus 로고    scopus 로고
    • Advanced glycation end products: Sparking the development of diabetic vascular injury
    • Goldin A, Beckman JA, Schmidt AM, Creager MA. Advanced glycation end products: sparking the development of diabetic vascular injury. Circulation 114: 597-605, 2006.
    • (2006) Circulation , vol.114 , pp. 597-605
    • Goldin, A.1    Beckman, J.A.2    Schmidt, A.M.3    Creager, M.A.4
  • 18
    • 0029846701 scopus 로고    scopus 로고
    • Regulation of hepatic de novo lipogenesis in humans
    • Hellerstein MK, Schwarz JM, Neese RA. Regulation of hepatic de novo lipogenesis in humans. Annu Rev Nutr 16: 523-557, 1996.
    • (1996) Annu Rev Nutr , vol.16 , pp. 523-557
    • Hellerstein, M.K.1    Schwarz, J.M.2    Neese, R.A.3
  • 19
    • 66449086312 scopus 로고    scopus 로고
    • Dietary sugars: A fat difference
    • Hofmann SM, Tschop MH. Dietary sugars: a fat difference. J Clin Invest 119: 1089-1092, 2009.
    • (2009) J Clin Invest , vol.119 , pp. 1089-1092
    • Hofmann, S.M.1    Tschop, M.H.2
  • 20
    • 34948892098 scopus 로고    scopus 로고
    • Dietary advanced lipid oxidation endproducts are risk factors to human health
    • Kanner J. Dietary advanced lipid oxidation endproducts are risk factors to human health. Mol Nutr Food Res 51: 1094-1101, 2007.
    • (2007) Mol Nutr Food Res , vol.51 , pp. 1094-1101
    • Kanner, J.1
  • 22
    • 70350131993 scopus 로고    scopus 로고
    • Replacing dietary glucose with fructose increases ChREBP activity and SREBP-1 protein in rat liver nucleus
    • Koo HY, Miyashita M, Cho BH, Nakamura MT. Replacing dietary glucose with fructose increases ChREBP activity and SREBP-1 protein in rat liver nucleus. Biochem Biophys Res Commun 390: 285-289, 2009.
    • (2009) Biochem Biophys Res Commun , vol.390 , pp. 285-289
    • Koo, H.Y.1    Miyashita, M.2    Cho, B.H.3    Nakamura, M.T.4
  • 27
    • 0026703158 scopus 로고
    • Immunochemical detection of advanced glycosylation end products in vivo
    • Makita Z, Vlassara H, Cerami A, Bucala R. Immunochemical detection of advanced glycosylation end products in vivo. J Biol Chem 267: 5133-5138, 1992.
    • (1992) J Biol Chem , vol.267 , pp. 5133-5138
    • Makita, Z.1    Vlassara, H.2    Cerami, A.3    Bucala, R.4
  • 29
    • 81055126867 scopus 로고    scopus 로고
    • Dietary phospholipids ameliorate fructose-induced hepatic lipid and metabolic abnormalities in rats
    • Mori T, Kondo H, Hase T, Murase T. Dietary phospholipids ameliorate fructose-induced hepatic lipid and metabolic abnormalities in rats. J Nutr 141: 2003-2009, 2011.
    • (2011) J Nutr , vol.141 , pp. 2003-2009
    • Mori, T.1    Kondo, H.2    Hase, T.3    Murase, T.4
  • 30
    • 77951226125 scopus 로고    scopus 로고
    • Effects of a short-term overfeeding with fructose or glucose in healthy young males
    • Ngo Sock ET, Lê KA, Ith M, Kreis R, Boesch C, Tappy L. Effects of a short-term overfeeding with fructose or glucose in healthy young males. Br J Nutr 103: 939-943, 2010.
    • (2010) Br J Nutr , vol.103 , pp. 939-943
    • Ngo Sock, E.T.1    Lê, K.A.2    Ith, M.3    Kreis, R.4    Boesch, C.5    Tappy, L.6
  • 31
    • 0033613126 scopus 로고    scopus 로고
    • Sterols regulate cycling of SREBP cleavage-activating protein (SCAP) between endoplasmic reticulum and Golgi
    • Nohturfft A, Bose-Boyd RA, Scheek S, Goldstein JL, Brown MS. Sterols regulate cycling of SREBP cleavage-activating protein (SCAP) between endoplasmic reticulum and Golgi. Proc Natl Acad Sci USA 96: 11235-11240, 1999.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 11235-11240
    • Nohturfft, A.1    Bose-Boyd, R.A.2    Scheek, S.3    Goldstein, J.L.4    Brown, M.S.5
  • 32
    • 84856756928 scopus 로고    scopus 로고
    • The role of fructose-enriched diets in mechanisms of nonalcoholic fatty liver disease
    • Nomura K, Yamanouchi T. The role of fructose-enriched diets in mechanisms of nonalcoholic fatty liver disease. J Nutr Biochem 23: 203-208, 2012.
    • (2012) J Nutr Biochem , vol.23 , pp. 203-208
    • Nomura, K.1    Yamanouchi, T.2
  • 33
    • 77953514271 scopus 로고    scopus 로고
    • Soft drinks consumption and nonalcoholic fatty liver disease
    • Nseir W, Nassar F, Assy N. Soft drinks consumption and nonalcoholic fatty liver disease. World J Gastroenterol 16: 2579-2588, 2010.
    • (2010) World J Gastroenterol , vol.16 , pp. 2579-2588
    • Nseir, W.1    Nassar, F.2    Assy, N.3
  • 34
  • 37
    • 77956176288 scopus 로고    scopus 로고
    • Sterol metabolism and SREBP activation
    • Sato R. Sterol metabolism and SREBP activation. Arch Biochem Biophys 501: 177-181, 2010.
    • (2010) Arch Biochem Biophys , vol.501 , pp. 177-181
    • Sato, R.1
  • 38
  • 39
    • 84884372459 scopus 로고    scopus 로고
    • Hepatocyte methylglyoxal (MG) resistance is overcome by inhibiting aldo-keto reductases and glyoxalase I catalysed MG metabolism
    • In:, edited by Weiner H, Plapp B, Lindahl R, Maser E. West Lafayette, IN: Purdue Univ. Press
    • Shangari N, Poon R, O'Brien PJ. Hepatocyte methylglyoxal (MG) resistance is overcome by inhibiting aldo-keto reductases and glyoxalase I catalysed MG metabolism. In: Enzymology and Molecular Biology of Carbonyl Metabolism, edited by Weiner H, Plapp B, Lindahl R, Maser E. West Lafayette, IN: Purdue Univ. Press, vol. 12, p. 266-275, 2005.
    • (2005) Enzymology and Molecular Biology of Carbonyl Metabolism , vol.12 , pp. 266-275
    • Shangari, N.1    Poon, R.2    O'Brien, P.J.3
  • 40
    • 79960126783 scopus 로고    scopus 로고
    • Effects of 4-week very-high-fructose/glucose diets on insulin sensitivity, visceral fat and intrahepatic lipids: An exploratory trial
    • Silbernagel G, Machann J, Unmuth S, Schick F, Stefan N, Häring HU, Fritsche A. Effects of 4-week very-high-fructose/glucose diets on insulin sensitivity, visceral fat and intrahepatic lipids: an exploratory trial. Br J Nutr 106: 79-86, 2011.
    • (2011) Br J Nutr , vol.106 , pp. 79-86
    • Silbernagel, G.1    McHann, J.2    Unmuth, S.3    Schick, F.4    Stefan, N.5    Häring, H.U.6    Fritsche, A.7
  • 41
    • 0035135246 scopus 로고    scopus 로고
    • Advanced glycation end-products: A review
    • Singh R, Barden A, Mori T, Beilin L. Advanced glycation end-products: a review. Diabetologia 44: 129-146, 2001.
    • (2001) Diabetologia , vol.44 , pp. 129-146
    • Singh, R.1    Barden, A.2    Mori, T.3    Beilin, L.4
  • 43
    • 0024514306 scopus 로고
    • Nonenzymatic glycation of bovine serum albumin by fructose (fructation). Comparison with the Maillard reaction initiated by glucose
    • Suarez G, Rajaram R, Oronsky AL, Gawinowicz MA. Nonenzymatic glycation of bovine serum albumin by fructose (fructation). Comparison with the Maillard reaction initiated by glucose. J Biol Chem 264: 3674-3679, 1989.
    • (1989) J Biol Chem , vol.264 , pp. 3674-3679
    • Suarez, G.1    Rajaram, R.2    Oronsky, A.L.3    Gawinowicz, M.A.4
  • 45
    • 75149166672 scopus 로고    scopus 로고
    • Metabolic effects of fructose and the worldwide increase in obesity
    • Tappy L, Lê KA. Metabolic effects of fructose and the worldwide increase in obesity. Physiol Rev 90: 23-46, 2010.
    • (2010) Physiol Rev , vol.90 , pp. 23-46
    • Tappy, L.1    Lê, K.A.2
  • 46
    • 84870389895 scopus 로고    scopus 로고
    • Does fructose consumption contribute to non-alcoholic fatty liver disease?
    • Tappy L, Lê KA. Does fructose consumption contribute to non-alcoholic fatty liver disease? Clin Res Hepatol Gastroenterol 36: 554-560, 2012.
    • (2012) Clin Res Hepatol Gastroenterol , vol.36 , pp. 554-560
    • Tappy, L.1    Lê, K.A.2
  • 47
    • 39049102073 scopus 로고    scopus 로고
    • Non-alcoholic fatty liver disease, the metabolic syndrome and the risk of cardiovascular disease: The plot thickens
    • Targher G. Non-alcoholic fatty liver disease, the metabolic syndrome and the risk of cardiovascular disease: the plot thickens. Diabetologia 51: 444-450, 2008.
    • (2008) Diabetologia , vol.51 , pp. 444-450
    • Targher, G.1
  • 48
    • 66149120712 scopus 로고    scopus 로고
    • Endocrine and metabolic effects of consuming fructose-and glucose-sweetened beverages with meals in obese men and women: Influence of insulin resistance on plasma triglyceride responses
    • Teff KL, Grudziak J, Townsend RR, Dunn TN, Grant RW, Adams SH, Keim NL, Cummings BP, Stanhope KL, Havel PJ. Endocrine and metabolic effects of consuming fructose-and glucose-sweetened beverages with meals in obese men and women: influence of insulin resistance on plasma triglyceride responses. J Clin Endocrinol Metab 94: 1562-1569, 2009.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 1562-1569
    • Teff, K.L.1    Grudziak, J.2    Townsend, R.R.3    Dunn, T.N.4    Grant, R.W.5    Adams, S.H.6    Keim, N.L.7    Cummings, B.P.8    Stanhope, K.L.9    Havel, P.J.10
  • 49
    • 0242468729 scopus 로고    scopus 로고
    • Quantitative screening of advanced glycation endproducts in cellular and extracellular proteins by tandem mass spectrometry
    • Thornalley PJ, Battah S, Ahmed N, Karachalias N, Agalou S, Babaei-Jadidi R, Dawnay A. Quantitative screening of advanced glycation endproducts in cellular and extracellular proteins by tandem mass spectrometry. Biochem J 375: 581-592, 2003.
    • (2003) Biochem J , vol.375 , pp. 581-592
    • Thornalley, P.J.1    Battah, S.2    Ahmed, N.3    Karachalias, N.4    Agalou, S.5    Babaei-Jadidi, R.6    Dawnay, A.7
  • 50
    • 49449083979 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease in humans is associated with increased plasma endotoxin and plasminogen activator inhibitor 1 concentrations and with fructose intake
    • Thuy S, Ladurner R, Volynets V, Wagner S, Strahl S, Königsrainer A, Maier KP, Bischoff SC, Bergheim I. Nonalcoholic fatty liver disease in humans is associated with increased plasma endotoxin and plasminogen activator inhibitor 1 concentrations and with fructose intake. J Nutr 138: 1452-1455, 2008.
    • (2008) J Nutr , vol.138 , pp. 1452-1455
    • Thuy, S.1    Ladurner, R.2    Volynets, V.3    Wagner, S.4    Strahl, S.5    Königsrainer, A.6    Maier, K.P.7    Bischoff, S.C.8    Bergheim, I.9


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