Plasmid-mediated quinolone resistance genes, aac(6′)-Ib-cr, qnrS, qnrB, and qnrA, in urinary isolates of Escherichia coli and Klebsiella pneumoniae at a teaching hospital, Thailand

Japanese Journal of Infectious Diseases

Volumn 66, Issue 5, 2013, Pages 428-432

  Pasom, Woravit ^a   Chanawong, Aroonwadee ^a   Lulitanond, Aroonlug ^a   Wilailuckana, Chotechana ^a   Kenprom, Suthida ^a   Puang Ngern, Pirom ^a  

^a KHON KAEN UNIVERSITY   (Thailand)

Author keywords

Aminoglycoside acetyltransferase variant; Extended spectrum lactamases; Quinolone resistance protein

Indexed keywords

CIPROFLOXACIN; COTRIMOXAZOLE; EXTENDED SPECTRUM BETA LACTAMASE; GENTAMICIN; NALIDIXIC ACID; NETILMICIN; OFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; TETRACYCLINE;

AAC(6') IB CR GENE; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIAL METABOLISM; BACTERIUM CONJUGATION; BACTERIUM ISOLATE; CONSENSUS SEQUENCE; CONTROLLED STUDY; DISK DIFFUSION; DRUG EFFICACY; ENZYME SYNTHESIS; ESCHERICHIA COLI; GENE MUTATION; GENE TRANSFER; GENETIC ANALYSIS; GENOTYPE; KLEBSIELLA PNEUMONIAE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PHENOTYPE; PLASMID MEDIATED QUINOLONE RESISTANCE GENE; POLYMERASE CHAIN REACTION; QNRA GENE; QNRB GENE; QNRS GENE; SEQUENCE ALIGNMENT; STRAIN DIFFERENCE; TEACHING HOSPITAL; THAILAND; UNIVERSITY HOSPITAL; URINE CULTURE;

ANTI-BACTERIAL AGENTS; CONJUGATION, GENETIC; DRUG RESISTANCE, BACTERIAL; ESCHERICHIA COLI; GENE TRANSFER, HORIZONTAL; GENES, BACTERIAL; HOSPITALS, TEACHING; HUMANS; KLEBSIELLA PNEUMONIAE; MOLECULAR TYPING; PLASMIDS; QUINOLONES; THAILAND; URINARY TRACT INFECTIONS; URINE;

EID: 84884403122     PISSN: 13446304     EISSN: 18842836     Source Type: Journal    
DOI: 10.7883/yoken.66.428     Document Type: Article

References (28)

1. Hooper, D.C. (1999): Mechanisms of fluoroquinolone resistance. Drug Resist. Updat., 2, 38-55.
2. Martfá nez-Martfá nez, L., Pascual, A. and Jacoby, G.A. (1998): Quinolone resistance from a transferable plasmid. Lancet, 351, 797-799.
3. Robicsek, A., Jacoby, G.A. and Hooper, D.C. (2006): The worldwide emergence of plasmid-mediated quinolone resistance. Lancet Infect. Dis., 6, 629-640.
4. Strahilevitz, J., Jacoby, G.A., Hooper, D.C., et al. (2009): Plasmid-mediated quinolone resistance: a multifaceted threat. Clin. Microbiol. Rev., 22, 664-689.
5. Robicsek, A., Strahilevitz, J., Jacoby, G.A., et al. (2006): Fluoroquinolone-modifying enzyme: a new adaptation of a common aminoglycoside acetyltransferase. Nat. Med., 12, 83-88.
6. Yamane, K., Wachino, J., Suzuki, S., et al. (2007): New plasmidmediated fluoroquinolone efflux pump, QepA, found in an Escherichia coli clinical isolate. Antimicrob. Agents Chemother., 51, 3354-3360.
7. Rodríguez-Martínez, J.M., Cano, M.E., Velasco, C., et al. (2011): Plasmid-mediated quinolone resistance: an update. J. Infect. Chemother., 17, 149-182.
8. Poirel, L., Pitout, J.D., Calvo, L., et al. (2006): In vivo selection of fluoroquinolone-resistant Escherichia coli isolates expressing plasmid-mediated quinolone resistance and expanded-spectrum b-lactamase. Antimicrob. Agents Chemother., 50, 1525-1527.
9. Poirel, L., Van De Loo, M., Mammeri, H., et al. (2005): Association of plasmid-mediated quinolone resistance with extendedspectrum b-lactamase VEB-1. Antimicrob. Agents Chemother., 49, 3091-3094.
10. Cavaco, L.M., Hendriksen, R.S. and Aarestrup, F.M. (2007): Plasmid-mediated quinolone resistance determinant qnrS1 detected in Salmonella enterica serovar Corvallis strains isolated in Denmark and Thailand. J. Antimicrob. Chemother., 60, 704-706.
11. Akiyama, T. and Khan, A.A. (2012): Isolation and characterization of small qnrS1-carrying plasmids from imported seafood isolates of Salmonella enterica that are highly similar to plasmids of clinical isolates. FEMS Immunol. Med. Microbiol., 64, 429-432.
12. Gunell, M., Webber, M.A., Kotilainen, P., et al. (2009): Mechanisms of resistance in nontyphoidal Salmonella enterica strains exhibiting a nonclassical quinolone resistance phenotype. Antimicrob. Agents Chemother., 53, 3832-3836.
13. Cattoir, V., Poirel, L., Rotimi, V., et al. (2007): Multiplex PCR for detection of plasmid-mediated quinolone resistance qnr genes in ESBL-producing enterobacterial isolates. J. Antimicrob. Chemother., 60, 394-397.
14. Park, C.H., Robicsek, A., Jacoby, G.A., et al. (2006): Prevalence in the United States of aac(6?)-Ib-cr encoding a ciprofloxacin-modifying enzyme. Antimicrob. Agents Chemother., 50, 3953-3955.
15. Kim, H.B., Park, C.H., Kim, C.J., et al. (2009): Prevalence of plasmid-mediated quinolone resistance determinants over a 9-year period. Antimicrob. Agents Chemother., 53, 639-645.
16. Cavaco, L.M., Hasman, H., Xia, S., et al. (2009): qnrD, a novel gene conferring transferable quinolone resistance in Salmonella enterica serovar Kentucky and Bovismorbificans strains of human origin. Antimicrob. Agents Chemother., 53, 603-608.
17. Snelling, A.M., Gerner-Smidt, P., Hawkey, P.M., et al. (1996): Validation of use of whole-cell repetitive extragenic palindromic sequence-based PCR (REP-PCR) for typing strains belonging to Acinetobacter calcoaceticus-Acinetobacter baumannii complex and application of the method to the investigation of a hospital outbreak. J. Clin. Microbiol., 34, 1193-1202.
18. Yang, H., Chen, H., Yang, Q., et al. (2008): High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6?)-Ibcr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. Antimicrob. Agents Chemother., 52, 4268-4273.
19. Zhou, T.L., Chen, X.J., Zhou, M.M., et al. (2011): Prevalence of plasmid-mediated quinolone resistance in Escherichia coli isolates inWenzhou, Southern China, 2002-2008. Jpn. J. Infect. Dis., 64, 55-57.
20. Nazik, H., Bektoäre, B., Oängen, B., et al. (2011): Plasmid-mediated quinolone resistance genes in Escherichia coli urinary isolates from two teaching hospitals in Turkey: coexistence of TEM, SHV, CTX-M and VEB-1 type b-lactamases. Trop. J. Pharm. Res., 10, 325-333.
21. Wang, M., Tran, J.H., Jacoby, G.A., et al. (2003): Plasmidmediated quinolone resistance in clinical isolates of Escherichia coli from Shanghai, China. Antimicrob. Agents Chemother., 47, 2242-2248.
22. de la Cruz, F. and Grinsted, J. (1982): Genetic and molecular characterization of Tn21, a multiple resistance transposon from R100.1. J. Bacteriol., 151, 222-228.
23. Szaboá, D., Kocsis, B., Roá kusz, L., et al. (2008): First detection of plasmid-mediated, quinolone resistance determinants qnrA, qnrB, qnrS and aac(6?)-Ib-cr in extended-spectrum b-lactamase (ESBL)-producing Enterobacteriaceae in Budapest, Hungary. J. Antimicrob. Chemother., 62, 630-632.
24. Cai, X., Li, C., Huang, J., et al. (2011): Prevalence of plasmidmediated quinolone resistance qnr gene in Central China. Afr. J. Microbiol. Res., 5, 975-978.
25. Lorenzo-Dá az, F. and Espinosa, M. (2009): Large-scale filter mating assay for intra-and inter-specific conjugal transfer of the promiscuous plasmid pMV158 in Gram-positive bacteria. Plasmid, 61, 65-70.
26. Clinical and Laboratory Standards Institute (2012): Performance standards for antimicrobial disk susceptibility test; 22nd information supplement. CLSI/NCCLS document M100-S22. Clinical and Laboratory Standards Institute, Wayne, Pa, USA.
27. Jeong, J.Y., Yoon, H.J., Kim, E.S., et al. (2005): Detection of qnr in clinical isolates of Escherichia coli from Korea. Antimicrob. Agents Chemother., 49, 2522-2524.
28. Versalovic, J., Koeuth, T. and Lupski, J.R. (1991): Distribution of repetitive DNA sequences in eubacteria and application to fingerprinting of bacterial genomes. Nucleic Acids Res., 19, 6823-6826.