Plasmid-mediated quinolone resistance genes in Escherichia coli urinary isolates from two teaching hospitals in Turkey: Coexistence of TEM, SHV, CTX-M and VEB-1 type β-lactamases

Tropical Journal of Pharmaceutical Research

Volumn 10, Issue 3, 2011, Pages 325-333

  Nazik, Hasan ^a   Bektöre, Bayhan ^b   Öngen, Betigül ^a   Ilktaç, Mehmet ^a   Özyurt, Mustafa ^b   Kuvat, Nuray ^a   Baylan, Orhan ^b   Keküllüoǧlu, Hatun ^a   Haznedaroǧlu, Tunçer ^b   Keleşoǧlu, Fatih Mehmet ^a  

^a ISTANBUL UNIVERSITY   (Turkey)

^b GATA HAYDARPASA TRAINING HOSPITAL   (Turkey)

Author keywords

lactamase; Aac(6 ) ib cr; CTX M 15; Quinolone resistance; VEB 1

Indexed keywords

CEFOTAXIME; CEFTAZIDIME; EXTENDED SPECTRUM BETA LACTAMASE; NORFLOXACIN; THIOL DERIVATIVE;

AAC(6') LB CR GENE; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM ISOLATE; BETA LACTAMASE CTX M GENE; BETA LACTAMASE SHV GENE; BETA LACTAMASE TEM 1 GENE; BETA LACTAMASE VEB 1 GENE; CONTROLLED STUDY; DISK DIFFUSION; ENZYME SYNTHESIS; ESCHERICHIA COLI; GENETIC TRAIT; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PLASMID; PLASMID MEDIATED QUINOLONE RESISTANCE GENE; POLYMERASE CHAIN REACTION; PREVALENCE; QEPA1 GENE; QNRA1 GENE; QNRS1 GENE; RANDOM AMPLIFIED POLYMORPHIC DNA; SPECIES COEXISTENCE; TURKEY (REPUBLIC);

EID: 79959939915     PISSN: 15965996     EISSN: 15969827     Source Type: Journal    
DOI: 10.4314/tjpr.v10i3.9     Document Type: Article

References (28)

1. Martinez-Martinez L, Pascual A, Jacoby GA. Quinolone resistance from a transferable plasmid. Lancet 1998; 351: 797-799.
2. Yamane K, Wachino J, Suzuki S, Kimura K, Shibata N, Kato H, Shibayama K, Konda T, Arakawa Y. New plasmid-mediated fluoroquinolone efflux pump, QepA, found in an Escherichia coli clinical isolate. Antimicrob Agents Chemother 2007; 51: 3354-3360.
3. Robicsek A, Strahilevitz J, Jacoby GA, Macielag M, Abbanat D, Park CH, Bush K, Hooper DC. Fluoroquinolone-modifying enzyme: a new adaptation of a common aminoglycoside acetyltransferase. Nat Med 2006; 12: 83-88.
4. Pitout JD. Multiresistant Enterobacteriaceae: new threat of an old problem. Expert Rev Anti Infect Ther 2008; 6: 657-669.
5. Korten V, Ulusoy S, Zarakolu P, Mete B. Antibiotic resistance surveillance over a 4-year period (2000-2003) in Turkey: results of the MYSTIC Program. Diagn Microbiol Infect Dis 2007; 59: 453-457.
6. Koksal F, Ak K, Kucukbasmaci O, Samasti M. Prevalence of antimicrobial resistance patternsof extended-spectrum beta-lactamaseproducing E. coli and K. pneumoniae isolated from blood cultures in an Istanbul University Hospital. Chemother 2009; 55: 293-297.
7. Fedler KA, Biedenbach DJ, Jones RN. Assessment of pathogen frequency and resistance patterns among pediatric patient isolates: report from the 2004 SENTRY Antimicrobial Surveillance Program on 3 continents. Diagn Microbiol Infect Dis 2006; 56: 427-436.
8. Nazik H, Poirel L, Nordmann P. Further identification of plasmid-mediated quinolone resistance determinant in Enterobacteriaceae in Turkey. Antimicrob Agents Chemother 2005; 49: 2146-2147.
9. Nazik H, Ilktaç M, Öngen B. Prevalence of qnrA, qnrB, qnrS and aac(6')-Ib-cr (in qnr-positive isoalates) among the ESBL-positive and/or ciprofloxacin-resistant isolates in Turkey. J Chemother 2009; 21: 219-221.
10. Nazik H, Öngen B, Kuvat N. Investigation of plasmid-mediated quinolone resistance among isolates obtained in a Turkish intensive care unit. Jpn J Infect Dis 2008; 61: 310-312.
11. Gulay Z, Bicmen M, Gur D, on behalf of the Hitit-2 study group. Prevalance and diversity of plasmid-mediated quinolone resistance genes in extended-spectrum beta-lactamase positive Escherichia coli and Klebsiella pneumoniae: first report of qepA from Turkey. Clin Microbiol Infect 2010; 16 (Suppl 2): 193.
12. Clinical and Laboratory Standards Institute: Performance Standards for Antimicrobial Susceptibility Testing: Nineteenth Informational Supplement M100-S19, CLSI, Wayne, Pa; 2009.
13. Nazik H, Ongen B, Erturan Z, Salcioglu M. Genotype and antibiotic susceptibility patterns of Pseudomonas aeruginosa and Stenotrophomonas maltophilia isolated from cystic fibrosis patients. Jpn J Infect Dis 2007; 60: 82-86.
14. Wang M, Sahm DF, Jacoby GA, Hooper DC. Emerging plasmid-mediated quinolone resistance associated with the qnr gene in Klebsiella pneumoniae clinical isolates in the United States. Antimicrob Agents Chemother 2004; 48: 1295-1299.
15. Pallecchi L, Bartoloni A, Fiorelli C, Mantella A, Di Maggio T, Gamboa H, Gotuzzo E, Kronvall G, Paradisi F, Rossolini GM. Rapid dissemination and diversity of CTX-M extended-spectrum beta-lactamase genes in commensal Escherichia coli isolates from healthy children from low-resource settings in Latin America. Antimicrob Agents Chemother 2007; 51: 2720-2725.
16. Poirel L, Van De Loo M, Mammeri H, Nordmann P. Association of plasmid-mediated quinolone resistance with extended-spectrum betalactamase VEB-1. Antimicrob Agents Chemother 2005; 49: 3091-3094.
17. Cattoir V, Poirel L, Rotimi V, Soussy CJ, Nordmann P. Multiplex PCR for detection of plasmidmediated quinolone resistance qnr genes in ESBL-producing enterobacterial isolates. J Antimicrob Chemother 2007; 60: 394-397.
18. Cavaco LM, Hasman H, Xia S, Aarestrup FM. qnrD, a Novel Gene Conferring Transferable Quinolone Resistance in Salmonella enterica Serovar Kentucky and BovismorbificansStrains of Human Origin. Antimicrob Agents Chemother 2009; 53: 603-608.
19. Canton R, Coque TM. The CTX-M beta-lactamase pandemic. Curr Opin Microbiol 2006; 9: 466-475.
20. Aktas Z, Gönüllü N, Kayacan ÇB, Özdem A, Carattoli A, Yong DE, Walsh T. CTX-M-15 Carried On Incn-Type Plasmids in Klebsiella pneumoniae. Türkiye Klinikleri J Med Sci 2009;29.
21. Yumuk Z, Afacan G, Nicolas-Chanoine MH, Sotto A, Lavigne JP. Turkey: a further country concerned by community-acquired Escherichia coli clone O25-ST131 producing CTX-M-15. J Antimicrob Chemother 2008; 62: 284-288.
22. Martinez-Martinez L, Eliecer Cano M, Manuel Rodriguez-Martinez J, Calvo J, Pascual A. Plasmid-mediated quinolone resistance. Expert Rev Anti Infect Ther 2008; 6: 685-711.
23. Oktem IM, Gulay Z, Bicmen M, Gur D. qnrA prevalence in extended-spectrum betalactamase- positive Enterobacteriaceae isolates from Turkey. Jpn J Infect Dis 2008; 61: 13-17.
24. Potron A, Poirel L, Bernaben S, Monnet X, Richard C, Nordmann P. Nosocomial spread of ESBLpositive Enterobacter cloacae co expressing plasmid-mediated quinolone resistance Qnr determinants in one hospital in France. J Antimicrobl Chemother 2009; 64(3): 653-654.
25. Amin AK, Wareham DW. Plasmid-mediated quinolone resistance genes in Enterobacteriaceae isolates associated with community and nosocomial urinary tract infection in East London, UK. Int J Antimicrob Agents 2009; 34: 490-503.
26. Hu FP, Xu XG, Zhu DM, Wang MG. Coexistence of qnrB4 and qnrS1 in a clinical strain of Klebsiella pneumoniae. Acta Pharmacol Sin 2008; 29: 320-324.
27. Yamane K, Wachino J, Suzuki S, Arakawa Y. Plasmid-mediated qepA gene among Escherichia coli clinical isolates from Japan. Antimicrob Agents Chemother 2008; 52: 1564-1566.
28. Cattoir V, Poirel L, Nordmann P. Plasmid-mediated quinolone resistance pump QepA2 in an Escherichia coli isolate from France. Antimicrob Agents Chemother 2008; 52: 3801-3804.