Chitosan oligosaccharides protect rat primary hippocampal neurons from oligomeric β-amyloid 1-42-induced neurotoxicity

Neuroscience Letters

Volumn 554, Issue , 2013, Pages 64-69

  Dai, Xueling ^a,b   Chang, Ping ^a   Zhu, Qingzhu ^a   Liu, Wenjuan ^a   Sun, Yaxuan ^a   Zhu, Shigong ^b   Jiang, Zhaofeng ^a  

^a BEIJING UNION UNIVERSITY   (China)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Amyloid peptide; Alzheimer's disease; Chitosan oligosaccharides; Neurotoxicity

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; CASPASE 3; CHITOSAN; CHITOSAN OLIGOSACCHARIDE; LACTATE DEHYDROGENASE; OLIGOSACCHARIDE; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; HIPPOCAMPAL NEURONAL CULTURE; LIPID PEROXIDATION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT;

1,1,1,3,3,3-HEXAFLUORO-2-PROPANOL; 2′,7′-DICHLOROFLUORESCIN DIACETATE; AD; ALZHEIMER'S DISEASE; AMYLOID PRECURSOR PROTEIN; APP; AΒ; AΒ42; C-JUN N-TERMINAL KINASE; CCK-8; CELL COUNTING KIT-8; CHITOSAN OLIGOSACCHARIDES; COSS; DCFH-DA; HFIP; JNK; LACTATE DEHYDROGENASE; LDH; MALONDIALDEHYDE; MAPK; MDA; MITOGEN ACTIVATED PROTEIN KINASE; NEUROFIBRILLARY TANGLES; NEUROTOXICITY; NFTS; REACTIVE OXYGEN SPECIES; ROS; SENILE PLAQUES; SPS; Β-AMYLOID FRAGMENTS 1-42; Β-AMYLOID PEPTIDE;

AMYLOID BETA-PEPTIDES; ANIMALS; CASPASE 3; CELL SURVIVAL; CHITOSAN; HIPPOCAMPUS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIPID PEROXIDATION; NEURONS; OLIGOSACCHARIDES; OXIDATIVE STRESS; PEPTIDE FRAGMENTS; PHOSPHORYLATION; PRIMARY CELL CULTURE; RATS; REACTIVE OXYGEN SPECIES;

EID: 84884385432     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2013.08.046     Document Type: Article

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