Virulence Potential and Genome-Wide Characterization of Drug Resistant Streptococcus pneumoniae Clones Selected In Vivo by the 7-Valent Pneumococcal Conjugate Vaccine

PLoS ONE

Volumn 8, Issue 9, 2013, Pages

  Frazão, Nelson ^a,d   Hiller, N Luisa ^b,c   Powell, Evan ^b   Earl, Josh ^b   Ahmed, Azad ^b   Sá Leão, Raquel ^a   de Lencastre, Hermínia ^a,d   Ehrlich, Garth D ^b   Tomasz, Alexander ^d  

^a INSTITUTO DE TECNOLOGIA QUÍMICA E BIOLÓGICA   (Portugal)

^b ALLEGHENY GENERAL HOSPITAL   (United States)

^c CARNEGIE MELLON UNIVERSITY   (United States)

^d ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PNEUMOCOCCUS VACCINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL GENOME; BACTERIAL LOAD; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM ISOLATE; CLONAL VARIATION; COLONY FORMING UNIT; CONTROLLED STUDY; FEMALE; GENETIC ASSOCIATION; GENETIC SIMILARITY; GENOME ANALYSIS; MOLECULAR CLONING; MOUSE; NONHUMAN; PHYLOGENY; SEQUENCE ANALYSIS; STREPTOCOCCUS PNEUMONIA; STREPTOCOCCUS PNEUMONIAE; SURVIVAL TIME;

ANIMALS; BACTERIAL CAPSULES; DISEASE MODELS, ANIMAL; DRUG RESISTANCE, BACTERIAL; FEMALE; GENOME, BACTERIAL; GENOME-WIDE ASSOCIATION STUDY; MICE; PHYLOGENY; PNEUMOCOCCAL INFECTIONS; PNEUMOCOCCAL VACCINES; POLYMORPHISM, GENETIC; SEQUENCE ANALYSIS, DNA; STREPTOCOCCUS PNEUMONIAE; VACCINES, CONJUGATE; VIRULENCE;

EID: 84884358593     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0074867     Document Type: Article

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