Method development for pharmaceutics: Some solutions for tuning selectivity in reversed phase and hydrophilic interaction liquid chromatography

Journal of Pharmaceutical and Biomedical Analysis

Volumn 63, Issue , 2012, Pages 95-105

  Ruta, Josephine ^a   Boccard, Julien ^a   Cabooter, Deirdre ^b   Rudaz, Serge ^a   Desmet, Gert ^b   Veuthey, Jean Luc ^a   Guillarme, Davy ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

Author keywords

Column coupler; HILIC; Orthogonality; RPLC; UHPLC

Indexed keywords

ANTIHISTAMINIC AGENT;

ARTICLE; CONTROLLED STUDY; DRUG IMPURITY; ELUTION; HYDROPHILIC INTERACTION CHROMATOGRAPHY; MOBILE PHASE PH; PH; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; PROCESS DEVELOPMENT; REVERSED PHASE LIQUID CHROMATOGRAPHY;

BUFFERS; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, LIQUID; CHROMATOGRAPHY, REVERSE-PHASE; DEALKYLATION; DRUG COMBINATIONS; DRUG CONTAMINATION; DRUG STABILITY; HISTAMINE ANTAGONISTS; HYDROGEN-ION CONCENTRATION; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MULTIVARIATE ANALYSIS; PHARMACEUTICAL PREPARATIONS; PRINCIPAL COMPONENT ANALYSIS; SOLVENTS; TECHNOLOGY, PHARMACEUTICAL;

EID: 84858075864     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2012.01.019     Document Type: Article

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