Design considerations for a combined microct and fluorescence diffuse optical tomography system

Biomedical Optics, BIOMED 2008

Volumn , Issue , 2008, Pages

  Kepshire, Dax ^a   Mincu, Niculae ^b   Hutchins, Michael ^b   Leblond, Frederic ^b   Pogue, Brian W ^a   Khayat, Mario ^b  

^a DARTMOUTH COLLEGE   (United States)

^b ART Advanced Research Technologies Inc   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORESCENCE; OPTICAL TOMOGRAPHY;

DESIGN CONSIDERATIONS; FLUORESCENCE DIFFUSE OPTICAL TOMOGRAPHY; FUNCTIONAL IMAGING; MICRO CT; SMALL ANIMAL; SOURCE DETECTORS;

COMPUTERIZED TOMOGRAPHY;

EID: 84884327625     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1364/biomed.2008.bsue82     Document Type: Conference Paper

References (18)

1. Ntziachristos, V., et al., Concurrent MRI and diffuse optical tomography of breast after indocyanine green enhancement. Proceedings of the National Academy of Sciences of the United States of America, 2000. 97(6): p. 2767-72.
2. Pogue, B.W., et al., Quantitative Hemoglobin Tomography with Diffuse Near-Infrared Spectroscopy: Pilot Results in the Breast. Radiology, 2001. 218(1): p. 261-6.
3. Ntziachristos, V., et al., MRI-guided diffuse optical spectroscopy of malignant and benign breast lesions. Neoplasia, 2002. 4(4): p. 347-54.
4. Corlu, A., et al., Diffuse optical tomography with spectral constraints and wavelength optimization. Applied Optics, 2005. 44(11): p. 2082-93.
5. Sevick-Muraca, E.M., J.P. Houston, and M. Gurfinkel, Fluorescence-enhanced, near infrared diagnostic imaging with contrast agents. Current Opinion in Chemical Biology, 2002. 6(5): p. 642-50.
6. Ntziachristos, V., C. Bremer, and R. Weissleder, Fluorescence imaging with near-infrared light: new technological advances that enable in vivo molecular imaging. European Radiology, 2003. 13(1): p. 195-208.
7. Weissleder, R., Scaling down imaging: molecular mapping of cancer in mice. Nature Reviews. Cancer., 2002. 2(1): p. 11-8.
8. Weissleder, R., et al., In vivo imaging of tumors with protease-activated near-infrared fluorescent probes. Nature Biotechnology., 1999. 17(4): p. 375-8.
9. Ntziachristos, V., et al., Fluorescence molecular tomography resolves protease activity in vivo. Nature Medicine, 2002. 8(7): p. 757-60.
10. Pogue, B.W., S.L. Gibbs, and B. Chen, Fluorescence Imaging In Vivo: Raster Scanned Point-Source Imaging Provides More Accurate Quantification than Broad Beam Geometries. Tech. Cancer Res. Treat., 2004. 3(1): p. 15-21.
11. Ntziachristos, V., et al., Looking and listening to light: the evolution of whole-body photonic imaging. Nature Biotechnology, 2005. 23(3): p. 313-20.
12. Pogue, B.W., et al., Image analysis methods for diffuse optical tomography. J. Biomed. Opt., 2006. 11(3): p. 033001.
13. Barbour, R.L., et al., MRI-Guided Optical Tomography: Prospects and Computation for a New Imaging Method. IEEE Comp. Sci. Eng., 1995. 2: p. 63-77.
14. Brooksby, B., et al., Imaging Breast Adipose and Fibroglandular Tissue Molecular Signatures using Hybrid MRI-Guided Near-Infrared Spectral Tomography. PNAS, 2006. 103: p. 8828-8833
15. Brooksby, B., et al., Combining near infrared tomography and magnetic resonance imaging to study in vivo breast tissue: implementation of a Laplacian-type regularization to incorporate magentic reasonance structure. J. Biomed. Opt., 2005. 10(5): p. 0515041-10
16. Zhu, Q., N. Chen, and S.H. Kurtzman, Imaging tumor angiogenesis by use of combined near-infrared diffusive light and ultrasound. Optics Letters, 2003. 28(5): p. 337-9.
17. Zhu, Q., et al., Utilizing optical tomography with ultrasound localization to image heterogeneous hemoglobin distribution in large breast cancers. Neoplasia, 2005. 7(3): p. 263-70.
18. Patterson, M.S. and B.W. Pogue, Mathimatical model for time-resolved and frequency-domain fluorescence spectroscopy in biological tissues. Appl. Opt., 1994. 33(10): p. 1963-1974.