CD40 ligand, Bcl-2, and Bcl-x(L) spare group I Burkitt lymphoma cells from CD77-directed killing via Verotoxin-1 B chain but fail to protect against the holotoxin

Cell Death and Differentiation

Volumn 7, Issue 9, 2000, Pages 785-794

  Gordon, J ^a   Challa, A ^a   Levens, J M ^a,b   Gregory, C D ^b   Williams, J M ^c   Armitage, R J ^d   Cook, J P ^e   Roberts, L M ^e   Lord, J M ^e  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^c QUEEN ELIZABETH HOSPITAL   (United Kingdom)

^d AMGEN INC   (United States)

^e UNIVERSITY OF WARWICK   (United Kingdom)

Author keywords

Apoptosis; CD40; CD77; Lymphoma; Verotoxin

Indexed keywords

GLOBOTRIAOSYLCERAMIDE; GLYCOPROTEIN GP 39; GLYCOSPHINGOLIPID; HOLOTOXIN; PROTEIN BCL 2; PROTEIN BCL X; RECEPTOR; TOXIN; UNCLASSIFIED DRUG; VEROTOXIN;

ANTIGEN EXPRESSION; ARTICLE; B LYMPHOCYTE; BURKITT LYMPHOMA; CELL DEATH; CELL DIFFERENTIATION; CELL KILLING; CELL LINEAGE; CELL PROTECTION; CONTROLLED STUDY; ESCHERICHIA COLI; FOLLICULAR LYMPHOMA; HUMAN; HUMAN CELL; LYMPHOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SURVIVAL;

EID: 0033828559     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4400710     Document Type: Article

References (61)

1. Pathogenesis of Shigella diarrhea XI. Isolation of a shigella toxin-binding glycolipid from rabbit jejunum and HeLa cells and its identification as globotriaosylceramide
2. Identification of the carbohydrate receptor for Shiga toxin produced by Shigella dysenteriae type 1
3. Glycolipid binding of purified and recombinant Escherichia coli-produced verotoxin in vitro
4. Induction of verotoxin sensitivity in receptor-deficient cell lines using the receptor glycolipid globotriaosylceramide
5. Verotoxin-binding in human renal sections
6. Shiga toxin 1 elicits diverse biologic responses in mesangial cells
7. Differentiation-associated toxin receptor modulation, cytokine production, and sensitivity to Shia-like toxins in human monocytes and monocytic cell lines
8. Evidence that verotoxins from Escherichia coli bind to P blood group antigens of human erythrocytes in vitro
9. Quantitative analysis of molecules which distinguish functional compartments within germinal centers
10. Germinal centers
11. Monoclonal antibody against a Burkitt lymphoma associated antigen
12. Endemic Burkitt's lymphoma: Phenotypic analysis of tumour biopsy cells and of dreived tumor cell lines
13. Isolation of a normal B cell subset with a Burkitt-like phenotype and transformation in vitro with Epstein-Barr virus
14. Immunophenotypic characterization of follicle-center-cell-derived non-Hodgkin's lymphomas
15. Role of processing and intracellular transport for optimal toxicity of Shiga toxin and toxin mutants
16. Surfing on a retrograde wave: How does Shiga toxin reach the endoplasmic reticulum?
17. Apoptosis induced in Burkitt's lymphoma cells via Gb3/CD77, a glycolipid antigen
18. Intracellular signalling events in CD77-mediated apoptosis of Burkitt's lymphoma cells
19. Germinal center cells express bcl-2 protein after activation by signals which prevent their entry to apoptosis
20. Suppression of apoptosis in normal and neoplastic human B lymphocytes by CD40 ligand is independent of Bcl-2 induction
21. Prevention of programmed cell death in Burkitt lymphoma cell lines by bcl-2-dependent and -independent mechanisms
22. Repression of apoptosis in human B-lymphoma cells by CD40-ligand and Bcl-2: Relationship to the cell-cycle and role of the retinoblastoma protein
23. Prolonged phenotypic, functional, and molecular change in group I Burkitt lymphoma cells on short-term exposure to CD40 ligand
24. Malignant lymphoma in African children. II. Pathological entity
25. Cellular degeneration associated with characteristic nuclear fine structure changes in the cells from two cases of Burkitt's malignant lymphoma syndrome
26. Histopathological definition of Burkitt's lymphoma
27. Mechanisms of antigen receptor-dependent apoptosis in human B lymphoma cell lines probed with a panel of 27 monoclonal antibodies
28. Activation of Epstein-Barr virus latent genes protects human B cells from death by apoptosis
29. Regulation of cell survival in Burkitt lymphoma: Implications from studies of apoptosis following cold-shock treatment
30. Transforming growth factor-β1 cooperates with anti-immunoglobulin for the induction of apoptosis in group I (biopsy-like) Burkitt lymphoma cell lines
31. Epstein-Barr virus markers in a series of Burkitt's lymphomas from the West Nile district of Uganda
32. Different Epstein-Barr virus B cell interactions in phenotypically distinct clones of a Burkitt's lymphoma cell line
33. Differences in B cell growth phenotype reflect novel patterns of Epstein-Barr virus latent gene expression in Burkitt's lymphoma cells
34. Biology of the lymphomas: Cytogenetics, molecular biology, and virology
35. Molecular diagnosis of lymphoma
36. Current management of follicular lymphoma
37. Up-regulation of Bcl-X(L) expression protects CD40-activated human B cells from Fas-mediated apoptosis
38. Bcl-x rather than Bcl-2 mediates CD40-dependent centrocyte survival in the germinal center
39. Induction of bcl-x by CD40 engagement rescues slg-induced apoptosis in murine B cells
40. The role of Bcl-X(L) in CD40-mediated rescue from anti-μ-induced apoptosis in WEHI-231 B lymphoma cells
41. Immune regulation by CD40 and its ligand gp39
42. A subset of CD4+ memory T cells contains preformed CD40 ligand that is rapidly but transiently expressed on their surface after activation through the T cell receptor complex
43. The CD40 ligand expressed by human B cells costimulates B cells responses
44. Regulation of cytoplasmic, surface and soluble forms of CD40 ligand in mouse B cells
45. CD77: An antigen of germinal center B cells entering apoptosis
46. Unbalanced expression of bcl-2 family proteins in follicular lymphoma: Contribution of CD40 signaling in promoting survival
47. The extrafollicular-to-follicular transition of human B lymphocytes: Induction of functional globotriaosylceramide (CD77) on high threshold occupancy of CD40
48. Epstein-Barr virus LMP-1 gene product induces A20 zinc finger protein expression by activating nuclear factor kB
49. The A20 zinc finger protein protects cells from tumor necrosis factor cytotoxicity
50. CD40 and epithelial cells: Across the great divide
51. Resistance to radiation-induced apoptosis in Burkitt's lymphoma cells is associated with defective ceramide signaling
52. Role of caspases in immunotoxin-induced apoptosis of cancer cells
53. Inhibition of caspases decreases verocytotoxin-1 (VT-1) mediated apoptosis but not cell death in vero cells
54. Escherichia coli O157:H7 gastroenteritis and the hemolytic uremic syndrome: An emerging infectious disease
55. The association between idiopathic hemolytic uremic syndrome and infection by verotoxin producing Escherichia coli
56. Anti-CD20 monoclonal antibodies as novel treatments for non-Hodgkin's lymphoma
57. Incorporation of an isoleucine zipper motif enhances the activity of soluble CD40L
58. Chemical synthesis of globotriose and galabiose: Relative stabilities of their complexes with Escherichia coli Shiga-like toxin-1 as determined by denaturation-titration with guanidinium hydrochloride
59. A system for production and rapid purification of large amounts of the Shia toxin/Shiga-like toxin I B subunit
60. GATA-1 but not SCL induces megakaryocytic differentiation in an early myeloid line