메뉴 건너뛰기




Volumn 302, Issue 6, 2012, Pages

Beyond proteinuria: VDR activation reduces renal inflammation in experimental diabetic nephropathy

Author keywords

Glomerular disease; Interleukins; Microalbuminuria

Indexed keywords

CALCITRIOL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PARICALCITOL; VITAMIN D RECEPTOR;

EID: 84858234310     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00090.2011     Document Type: Article
Times cited : (150)

References (41)
  • 3
    • 0027131837 scopus 로고
    • Partial prevention of active Heymann nephritis by 1-alpha,25 dihydroxyvitamin D-3
    • Branisteanu DD, Leenaerts P, Vandamme B, Bouillon R. Partial prevention of active Heymann nephritis by 1-alpha,25 dihydroxyvitamin D-3. Clin Exp Immunol 94: 412-417, 1993.
    • (1993) Clin Exp Immunol , vol.94 , pp. 412-417
    • Branisteanu, D.D.1    Leenaerts, P.2    Vandamme, B.3    Bouillon, R.4
  • 5
    • 66049093473 scopus 로고    scopus 로고
    • 1,25-Dihydroxyvitamin D3 suppresses high glucose-induced angiotensinogen expression in kidney cells by blocking the NF-_B pathway
    • Deb DK, Chen YZ, Zhang ZY, Zhang Y, Szeto FL, Wong KE, Kong J, Li YC. 1,25-Dihydroxyvitamin D3 suppresses high glucose-induced angiotensinogen expression in kidney cells by blocking the NF-_B pathway. Am J Physiol Renal Physiol 296: F1212-F1218, 2009.
    • (2009) Am J Physiol Renal Physiol , vol.296
    • Deb, D.K.1    Chen, Y.Z.2    Zhang, Z.Y.3    Zhang, Y.4    Szeto, F.L.5    Wong, K.E.6    Kong, J.7    Li, Y.C.8
  • 6
    • 77955875400 scopus 로고    scopus 로고
    • Combined vitamin D analog and AT1 receptor antagonist synergistically block the development of kidney disease in a model of type 2 diabetes
    • Deb DK, Sun T, Wong KE, Zhang Z, Ning G, Zhang Y, Kong J, Shi H, Chang A, Li YC. Combined vitamin D analog and AT1 receptor antagonist synergistically block the development of kidney disease in a model of type 2 diabetes. Kidney Int 77: 1000-1009, 2010.
    • (2010) Kidney Int , vol.77 , pp. 1000-1009
    • Deb, D.K.1    Sun, T.2    Wong, K.E.3    Zhang, Z.4    Ning, G.5    Zhang, Y.6    Kong, J.7    Shi, H.8    Chang, A.9    Li, Y.C.10
  • 7
    • 0242432597 scopus 로고    scopus 로고
    • Increased expression of ornithine decarboxylase in distal tubules of early diabetic rat kidneys: Are polyamines paracrine hypertrophic factors?
    • Deng A, Munger KA, Valdivielso JM, Satriano J, Lortie M, Blantz RC, Thomson SC. Increased expression of ornithine decarboxylase in distal tubules of early diabetic rat kidneys: are polyamines paracrine hypertrophic factors? Diabetes 52: 1235-1239, 2003.
    • (2003) Diabetes , vol.52 , pp. 1235-1239
    • Deng, A.1    Munger, K.A.2    Valdivielso, J.M.3    Satriano, J.4    Lortie, M.5    Blantz, R.C.6    Thomson, S.C.7
  • 8
    • 78149359262 scopus 로고    scopus 로고
    • Selective vitamin D receptor activation with paricalcitol for reduction of albuminuria in patients with type 2 diabetes (VITAL study): A randomised controlled trial
    • de Zeeuw D, Agarwal R, Amdahl M, Audhya P, Coyne D, Garimella T, Parving HH, Pritchett Y, Remuzzi G, Ritz E, Andress D. Selective vitamin D receptor activation with paricalcitol for reduction of albuminuria in patients with type 2 diabetes (VITAL study): a randomised controlled trial. Lancet 376: 1543-1551, 2010.
    • (2010) Lancet , vol.376 , pp. 1543-1551
    • de Zeeuw, D.1    Agarwal, R.2    Amdahl, M.3    Audhya, P.4    Coyne, D.5    Garimella, T.6    Parving, H.H.7    Pritchett, Y.8    Remuzzi, G.9    Ritz, E.10    Andress, D.11
  • 9
    • 44949105469 scopus 로고    scopus 로고
    • Activation of a local renin angiotensin system in podocytes by glucose
    • Durvasula RV, Shankland SJ. Activation of a local renin angiotensin system in podocytes by glucose. Am J Physiol Renal Physiol 294: F830-F839, 2008.
    • (2008) Am J Physiol Renal Physiol , vol.294
    • Durvasula, R.V.1    Shankland, S.J.2
  • 11
    • 70349251198 scopus 로고    scopus 로고
    • Oral paricalcitol in the treatment of patients with CKD and proteinuria: A randomized trial
    • Fishbane S, Chittineni H, Packman M, Dutka P, Ali N, Durie N. Oral paricalcitol in the treatment of patients with CKD and proteinuria: a randomized trial. Am J Kidney Dis 54: 647-652, 2009.
    • (2009) Am J Kidney Dis , vol.54 , pp. 647-652
    • Fishbane, S.1    Chittineni, H.2    Packman, M.3    Dutka, P.4    Ali, N.5    Durie, N.6
  • 12
    • 0022889757 scopus 로고
    • Leukosialin, a major sialoglycoprotein on human leukocytes as differentiation antigens
    • Fukuda M, Carlsson SR. Leukosialin, a major sialoglycoprotein on human leukocytes as differentiation antigens. Med Biol 64: 335-343,1986.
    • (1986) Med Biol , vol.64 , pp. 335-343
    • Fukuda, M.1    Carlsson, S.R.2
  • 14
    • 0036073755 scopus 로고    scopus 로고
    • 1,25-Dihydroxyvitamin D-3 is a negative endocrine regulator of the renin-angiotensin system
    • Li YC, Kong J, Wei MJ, Chen ZF, Liu SQ, Cao LP. 1,25-Dihydroxyvitamin D-3 is a negative endocrine regulator of the renin-angiotensin system. J Clin Invest 110: 229-238, 2002.
    • (2002) J Clin Invest , vol.110 , pp. 229-238
    • Li, Y.C.1    Kong, J.2    Wei, M.J.3    Chen, Z.F.4    Liu, S.Q.5    Cao, L.P.6
  • 16
    • 58949097006 scopus 로고    scopus 로고
    • The sudden demise of dual renin-angiotensin system blockade or the soft science of the surrogate end point
    • Messerli FH. The sudden demise of dual renin-angiotensin system blockade or the soft science of the surrogate end point. J Am Coll Cardiol 53: 468-470, 2009.
    • (2009) J Am Coll Cardiol , vol.53 , pp. 468-470
    • Messerli, F.H.1
  • 17
    • 34249868434 scopus 로고    scopus 로고
    • Combination therapy with an angiotensin-converting enzyme inhibitor and a vitamin D analog suppresses the progression of renal insufficiency in uremic rats
    • Mizobuchi M, Morrissey J, Finch JL, Martin DR, Liapis H, Akizawa T, Slatopolsky E. Combination therapy with an angiotensin-converting enzyme inhibitor and a vitamin D analog suppresses the progression of renal insufficiency in uremic rats. J Am Soc Nephrol 18: 1796-1806, 2007.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 1796-1806
    • Mizobuchi, M.1    Morrissey, J.2    Finch, J.L.3    Martin, D.R.4    Liapis, H.5    Akizawa, T.6    Slatopolsky, E.7
  • 18
    • 0038748305 scopus 로고    scopus 로고
    • Elevated levels of interleukin-18 and tumor necrosis factor-alpha in serum of patients with type 2 diabetes mellitus: Relationship with diabetic nephropathy
    • Moriwaki Y, Yamamoto T, Shibutani Y, Aoki E, Tsutsumi Z, Takahashi S, Okamura H, Koga M, Fukuchi M, Hada T. Elevated levels of interleukin-18 and tumor necrosis factor-alpha in serum of patients with type 2 diabetes mellitus: relationship with diabetic nephropathy. Metabolism 52: 605-608, 2003.
    • (2003) Metabolism , vol.52 , pp. 605-608
    • Moriwaki, Y.1    Yamamoto, T.2    Shibutani, Y.3    Aoki, E.4    Tsutsumi, Z.5    Takahashi, S.6    Okamura, H.7    Koga, M.8    Fukuchi, M.9    Hada, T.10
  • 19
    • 0029828633 scopus 로고    scopus 로고
    • Cell culture of podocytes
    • Mundel P, Kriz W. Cell culture of podocytes. Exp Nephrol 4: 263-266,1996.
    • (1996) Exp Nephrol , vol.4 , pp. 263-266
    • Mundel, P.1    Kriz, W.2
  • 20
    • 29644435472 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha gene expression in diabetic nephropathy: Relationship with urinary albumin excretion and effect of angiotensinconverting enzyme inhibition
    • Navarro JF, Milena FJ, Mora C, Leon C, Claverie F, Flores C, Garcia J. Tumor necrosis factor-alpha gene expression in diabetic nephropathy: relationship with urinary albumin excretion and effect of angiotensinconverting enzyme inhibition. Kidney Int Suppl S98-S102, 2005.
    • (2005) Kidney Int Suppl
    • Navarro, J.F.1    Milena, F.J.2    Mora, C.3    Leon, C.4    Claverie, F.5    Flores, C.6    Garcia, J.7
  • 21
    • 33846419118 scopus 로고    scopus 로고
    • Renal proinflammatory cytokine gene expression in diabetic nephropathy: Effect of angiotensin-converting enzyme inhibition and pentoxifylline administration
    • Navarro JF, Milena FJ, Mora C, Leon C, Garcia J. Renal proinflammatory cytokine gene expression in diabetic nephropathy: effect of angiotensin-converting enzyme inhibition and pentoxifylline administration. Am J Nephrol 26: 562-570, 2006.
    • (2006) Am J Nephrol , vol.26 , pp. 562-570
    • Navarro, J.F.1    Milena, F.J.2    Mora, C.3    Leon, C.4    Garcia, J.5
  • 22
    • 40449113524 scopus 로고    scopus 로고
    • The role of inflammatory cytokines in diabetic nephropathy
    • Navarro-Gonzalez JF, Mora-Fernandez C. The role of inflammatory cytokines in diabetic nephropathy. J Am Soc Nephrol 19: 433-442, 2008.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 433-442
    • Navarro-Gonzalez, J.F.1    Mora-Fernandez, C.2
  • 25
    • 0036170247 scopus 로고    scopus 로고
    • Tubular cell apoptosis and proliferation in the early phase of renal damage in uninephrectomized SHR
    • Rodriguez-Lopez AM, Flores O, Arevalo MA, Lopez-Novoa JM. Tubular cell apoptosis and proliferation in the early phase of renal damage in uninephrectomized SHR. Kidney Blood Pressure Res 25: 13-19, 2002.
    • (2002) Kidney Blood Pressure Res , vol.25 , pp. 13-19
    • Rodriguez-Lopez, A.M.1    Flores, O.2    Arevalo, M.A.3    Lopez-Novoa, J.M.4
  • 30
    • 0032925125 scopus 로고    scopus 로고
    • Cytokine network and resident renal cells in glomerular diseases
    • Schena FP. Cytokine network and resident renal cells in glomerular diseases. Nephrol Dial Transplant 14, Suppl 1: 22-26, 1999.
    • (1999) Nephrol Dial Transplant , vol.14 , Issue.SUPPL. 1 , pp. 22-26
    • Schena, F.P.1
  • 31
    • 0031749608 scopus 로고    scopus 로고
    • Effect of 1,25(OH)2 vitamin D-3 on glomerulosclerosis in subtotally nephrectomized rats
    • Schwarz U, Amann K, Orth SR, Simonaviciene A, Wessels S, Ritz E. Effect of 1,25(OH)2 vitamin D-3 on glomerulosclerosis in subtotally nephrectomized rats. Kidney Int 53: 1696-1705, 1998.
    • (1998) Kidney Int , vol.53 , pp. 1696-1705
    • Schwarz, U.1    Amann, K.2    Orth, S.R.3    Simonaviciene, A.4    Wessels, S.5    Ritz, E.6
  • 32
    • 54749105918 scopus 로고    scopus 로고
    • Paricalcitol inhibits renal inflammation by promoting vitamin D receptor-mediated sequestration of NF-kappaB signaling
    • Tan X, Wen X, Liu Y. Paricalcitol inhibits renal inflammation by promoting vitamin D receptor-mediated sequestration of NF-kappaB signaling. J Am Soc Nephrol 19: 1741-1752, 2008.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 1741-1752
    • Tan, X.1    Wen, X.2    Liu, Y.3
  • 33
    • 0036924775 scopus 로고    scopus 로고
    • Circulating MMP9, vitamin D and variation in the TIMP-1 response with VDR genotype: Mechanisms for inflammatory damage in chronic disorders?
    • Timms PM, Mannan N, Hitman GA, Noonan K, Mills PG, Syndercombe-Court Aganna E, Price CP, Boucher BJ. Circulating MMP9, vitamin D and variation in the TIMP-1 response with VDR genotype: mechanisms for inflammatory damage in chronic disorders? QJM 95: 787-796, 2002.
    • (2002) QJM , vol.95 , pp. 787-796
    • Timms, P.M.1    Mannan, N.2    Hitman, G.A.3    Noonan, K.4    Mills, P.G.5    Syndercombe-Court Aganna, E.6    Price, C.P.7    Boucher, B.J.8
  • 34
    • 67651235727 scopus 로고    scopus 로고
    • The physiology of vitamin D receptor activation
    • Valdivielso JM. The physiology of vitamin D receptor activation. Contrib Nephrol 163: 206-212, 2009.
    • (2009) Contrib Nephrol , vol.163 , pp. 206-212
    • Valdivielso, J.M.1
  • 35
    • 20044362239 scopus 로고    scopus 로고
    • From the periphery of the glomerular capillary wall toward the center of disease: Podocyte injury comes of age in diabetic nephropathy
    • Wolf G, Chen S, Ziyadeh FN. From the periphery of the glomerular capillary wall toward the center of disease: podocyte injury comes of age in diabetic nephropathy. Diabetes 54: 1626-1634, 2005.
    • (2005) Diabetes , vol.54 , pp. 1626-1634
    • Wolf, G.1    Chen, S.2    Ziyadeh, F.N.3
  • 37
    • 34250156384 scopus 로고    scopus 로고
    • Aberrant activation profile of cytokines and mitogenactivated protein kinases in type 2 diabetic patients with nephropathy
    • Wong CK, Ho AW, Tong PC, Yeung CY, Kong AP, Lun SW, Chan JC, Lam CW. Aberrant activation profile of cytokines and mitogenactivated protein kinases in type 2 diabetic patients with nephropathy. Clin Exp Immunol 149: 123-131, 2007.
    • (2007) Clin Exp Immunol , vol.149 , pp. 123-131
    • Wong, C.K.1    Ho, A.W.2    Tong, P.C.3    Yeung, C.Y.4    Kong, A.P.5    Lun, S.W.6    Chan, J.C.7    Lam, C.W.8
  • 38
    • 35648976022 scopus 로고    scopus 로고
    • 1,25-dihydroxyvitamin D3 suppresses renin gene transcription by blocking the activity of the cyclic AMP response element in the renin gene promoter
    • Yuan W, Pan W, Kong J, Zheng W, Szeto FL, Wong KE, Cohen R, Klopot A, Zhang Z, Li YC. 1,25-dihydroxyvitamin D3 suppresses renin gene transcription by blocking the activity of the cyclic AMP response element in the renin gene promoter. J Biol Chem 282: 29821-29830, 2007.
    • (2007) J Biol Chem , vol.282 , pp. 29821-29830
    • Yuan, W.1    Pan, W.2    Kong, J.3    Zheng, W.4    Szeto, F.L.5    Wong, K.E.6    Cohen, R.7    Klopot, A.8    Zhang, Z.9    Li, Y.C.10
  • 40
    • 34447530298 scopus 로고    scopus 로고
    • 1,25-Dihydroxyvitamin D3 targeting of NF-[kappa]B suppresses high glucose-induced MCP-1 expression in mesangial cells
    • Zhang Z, Yuan W, Sun L, Szeto FL, Wong KE, Li X, Kong J, Li YC. 1,25-Dihydroxyvitamin D3 targeting of NF-[kappa]B suppresses high glucose-induced MCP-1 expression in mesangial cells. Kidney Int 72: 193-201, 2007.
    • (2007) Kidney Int , vol.72 , pp. 193-201
    • Zhang, Z.1    Yuan, W.2    Sun, L.3    Szeto, F.L.4    Wong, K.E.5    Li, X.6    Kong, J.7    Li, Y.C.8
  • 41
    • 57349185929 scopus 로고    scopus 로고
    • Combination therapy with AT1 blocker and vitamin D analog markedly ameliorates diabetic nephropathy: Blockade of compensatory renin increase
    • Zhang Z, Zhang Y, Ning G, Deb DK, Kong J, Li YC. Combination therapy with AT1 blocker and vitamin D analog markedly ameliorates diabetic nephropathy: blockade of compensatory renin increase. Proc Natl Acad Sci USA 105: 15896-15901, 2008.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 15896-15901
    • Zhang, Z.1    Zhang, Y.2    Ning, G.3    Deb, D.K.4    Kong, J.5    Li, Y.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.