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Volumn 7, Issue 5, 2013, Pages 917-928

The metastasis-associated molecule C4.4A promotes tissue invasion and anchorage independence by associating with the alpha6beta4 integrin

Author keywords

Alpha6beta4; C4.4A; Laminin 332; Metastasis; MMP14; PI3K Akt

Indexed keywords

ALPHA6BETA4 INTEGRIN; CISPLATIN; LAMININ RECEPTOR; LAMININ RECEPTOR C4 4A; MATRIX METALLOPROTEINASE 14; MATRIX PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAD; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN KINASE B; UNCLASSIFIED DRUG;

EID: 84884290676     PISSN: 15747891     EISSN: 18780261     Source Type: Journal    
DOI: 10.1016/j.molonc.2013.05.002     Document Type: Article
Times cited : (9)

References (56)
  • 1
    • 28244478626 scopus 로고    scopus 로고
    • Beta4 integrin is a transforming molecule that unleashes Met tyrosine kinase tumorigenesis
    • Bertotti A., Comoglio P.M., Trusolino L. Beta4 integrin is a transforming molecule that unleashes Met tyrosine kinase tumorigenesis. Cancer Res. 2005, 65:10674-10679.
    • (2005) Cancer Res. , vol.65 , pp. 10674-10679
    • Bertotti, A.1    Comoglio, P.M.2    Trusolino, L.3
  • 2
    • 33745186855 scopus 로고    scopus 로고
    • Loss of beta4 integrin subunit reduces the tumorigenicity of MCF7 mammary cells and causes apoptosis upon hormone deprivation
    • Bon G., Folgiero V., Bossi G., Felicioni L., Marchetti A., Sacchi A., Falcioni R. Loss of beta4 integrin subunit reduces the tumorigenicity of MCF7 mammary cells and causes apoptosis upon hormone deprivation. Clin. Cancer Res. 2006, 12:3280-3287.
    • (2006) Clin. Cancer Res. , vol.12 , pp. 3280-3287
    • Bon, G.1    Folgiero, V.2    Bossi, G.3    Felicioni, L.4    Marchetti, A.5    Sacchi, A.6    Falcioni, R.7
  • 3
    • 34248215265 scopus 로고    scopus 로고
    • Involvement of alpha6beta4 integrin in the mechanisms that regulate breast cancer progression
    • Bon G., Folgiero V., Di Carlo S., Sacchi A., Falcioni R. Involvement of alpha6beta4 integrin in the mechanisms that regulate breast cancer progression. Breast Cancer Res. 2007, 9:203.
    • (2007) Breast Cancer Res. , vol.9 , pp. 203
    • Bon, G.1    Folgiero, V.2    Di Carlo, S.3    Sacchi, A.4    Falcioni, R.5
  • 4
    • 0032908323 scopus 로고    scopus 로고
    • Structure and function of hemidesmosomes: more than simple adhesion complexes
    • Borradori L., Sonnenberg A. Structure and function of hemidesmosomes: more than simple adhesion complexes. J.Invest. Dermatol. 1999, 112:411-418.
    • (1999) J.Invest. Dermatol. , vol.112 , pp. 411-418
    • Borradori, L.1    Sonnenberg, A.2
  • 5
    • 0029827830 scopus 로고    scopus 로고
    • Developmentally regulated expression of metastasis-associated antigens in the rat
    • Claas C., Herrmann K., Matzku S., Möller P., Zöller M. Developmentally regulated expression of metastasis-associated antigens in the rat. Cell. Growth Differ. 1996, 7:663-678.
    • (1996) Cell. Growth Differ. , vol.7 , pp. 663-678
    • Claas, C.1    Herrmann, K.2    Matzku, S.3    Möller, P.4    Zöller, M.5
  • 6
    • 0034686013 scopus 로고    scopus 로고
    • Integrin-mediated RON growth factor receptor phosphorylation requires tyrosine kinase activity of both the receptor and c-Src
    • Danilkovitch-Miagkova A., Angeloni D., Skeel A., Donley S., Lerman M., Leonard E.J. Integrin-mediated RON growth factor receptor phosphorylation requires tyrosine kinase activity of both the receptor and c-Src. J.Biol. Chem. 2000, 275:14783-14786.
    • (2000) J.Biol. Chem. , vol.275 , pp. 14783-14786
    • Danilkovitch-Miagkova, A.1    Angeloni, D.2    Skeel, A.3    Donley, S.4    Lerman, M.5    Leonard, E.J.6
  • 7
    • 0035085802 scopus 로고    scopus 로고
    • Keratinocyte migration requires alpha2beta1 integrin-mediated interaction with the laminin 5 gamma2 chain
    • Decline F., Rousselle P. Keratinocyte migration requires alpha2beta1 integrin-mediated interaction with the laminin 5 gamma2 chain. J.Cell. Sci. 2001, 114:811-823.
    • (2001) J.Cell. Sci. , vol.114 , pp. 811-823
    • Decline, F.1    Rousselle, P.2
  • 9
    • 0037463227 scopus 로고    scopus 로고
    • HAG-2 and hAG-3 human homologues of genes involved in differentiation are associated with oestrogen receptor-positive breast tumours and interact with metastasis gene C4.4a and dystroglycan
    • Fletcher G.C., Patel S., Tyson K., Adam P.J., Schenker M., Loader J.A., Daviet L., Legrain P., Parekh R., Harris A.L., Terrett J.A. hAG-2 and hAG-3 human homologues of genes involved in differentiation are associated with oestrogen receptor-positive breast tumours and interact with metastasis gene C4.4a and dystroglycan. Br. J. Cancer 2003, 88:579-585.
    • (2003) Br. J. Cancer , vol.88 , pp. 579-585
    • Fletcher, G.C.1    Patel, S.2    Tyson, K.3    Adam, P.J.4    Schenker, M.5    Loader, J.A.6    Daviet, L.7    Legrain, P.8    Parekh, R.9    Harris, A.L.10    Terrett, J.A.11
  • 10
    • 36248998112 scopus 로고    scopus 로고
    • Alpha6beta4 integrin activates Rac-dependent p21-activated kinase 1 to drive NF-kappaB-dependent resistance to apoptosis in 3D mammary acini
    • Friedland J.C., Lakins J.N., Kazanietz M.G., Chernoff J., Boettiger D., Weaver V.M. alpha6beta4 integrin activates Rac-dependent p21-activated kinase 1 to drive NF-kappaB-dependent resistance to apoptosis in 3D mammary acini. J.Cell. Sci. 2007, 120:3700-3712.
    • (2007) J.Cell. Sci. , vol.120 , pp. 3700-3712
    • Friedland, J.C.1    Lakins, J.N.2    Kazanietz, M.G.3    Chernoff, J.4    Boettiger, D.5    Weaver, V.M.6
  • 11
    • 34147176985 scopus 로고    scopus 로고
    • CEBPbeta, JunD and c-Jun contribute to the transcriptional activation of the metastasis-associated C4.4A gene
    • Fries F., Nazarenko I., Hess J., Claas A., Angel P., Zöller M. CEBPbeta, JunD and c-Jun contribute to the transcriptional activation of the metastasis-associated C4.4A gene. Int. J. Cancer 2007, 120:2135-2147.
    • (2007) Int. J. Cancer , vol.120 , pp. 2135-2147
    • Fries, F.1    Nazarenko, I.2    Hess, J.3    Claas, A.4    Angel, P.5    Zöller, M.6
  • 12
    • 78549232337 scopus 로고    scopus 로고
    • EGF-induced MAPK signaling inhibits hemidesmosome formation through phosphorylation of the integrin {beta}4
    • Frijns E., Sachs N., Kreft M., Wilhelmsen K., Sonnenberg A. EGF-induced MAPK signaling inhibits hemidesmosome formation through phosphorylation of the integrin {beta}4. J.Biol. Chem. 2010, 285:37650-37662.
    • (2010) J.Biol. Chem. , vol.285 , pp. 37650-37662
    • Frijns, E.1    Sachs, N.2    Kreft, M.3    Wilhelmsen, K.4    Sonnenberg, A.5
  • 13
    • 34748863597 scopus 로고    scopus 로고
    • Targeting integrin beta4 for cancer and anti-angiogenic therapy
    • Giancotti F.G. Targeting integrin beta4 for cancer and anti-angiogenic therapy. Trends Pharmacol. Sci. 2007, 28:506-511.
    • (2007) Trends Pharmacol. Sci. , vol.28 , pp. 506-511
    • Giancotti, F.G.1
  • 14
    • 3042820386 scopus 로고    scopus 로고
    • Structural analysis and tissue localization of human C4.4A: a protein homologue of the urokinase receptor
    • Hansen L.V., Gardsvoll H., Nielsen B.S., Lund L.R., Dano K., Jensen O.N., Ploug M. Structural analysis and tissue localization of human C4.4A: a protein homologue of the urokinase receptor. Biochem. J. 2004, 380:845-857.
    • (2004) Biochem. J. , vol.380 , pp. 845-857
    • Hansen, L.V.1    Gardsvoll, H.2    Nielsen, B.S.3    Lund, L.R.4    Dano, K.5    Jensen, O.N.6    Ploug, M.7
  • 15
    • 38349056461 scopus 로고    scopus 로고
    • Altered expression of the urokinase receptor homologue, C4.4A, in invasive areas of human esophageal squamous cell carcinoma
    • Hansen L.V., Laerum O.D., Illemann M., Nielsen B.S., Ploug M. Altered expression of the urokinase receptor homologue, C4.4A, in invasive areas of human esophageal squamous cell carcinoma. Int. J. Cancer 2008, 122:734-741.
    • (2008) Int. J. Cancer , vol.122 , pp. 734-741
    • Hansen, L.V.1    Laerum, O.D.2    Illemann, M.3    Nielsen, B.S.4    Ploug, M.5
  • 16
    • 34948886162 scopus 로고    scopus 로고
    • Tumour cell expression of C4.4A, a structural homologue of the urokinase receptor, correlates with poor prognosis in non-small cell lung cancer
    • Hansen L.V., Skov B.G., Ploug M., Rappot H. Tumour cell expression of C4.4A, a structural homologue of the urokinase receptor, correlates with poor prognosis in non-small cell lung cancer. Lung Cancer 2007, 58:260-266.
    • (2007) Lung Cancer , vol.58 , pp. 260-266
    • Hansen, L.V.1    Skov, B.G.2    Ploug, M.3    Rappot, H.4
  • 17
    • 0035972158 scopus 로고    scopus 로고
    • Inhibitory role of alpha 6 beta 4-associated erbB-2 and phosphoinositide 3-kinase in keratinocyte haptotactic migration dependent on alpha 3 beta 1 integrin
    • Hintermann E., Bilban M., Sharabi A., Quaranta V. Inhibitory role of alpha 6 beta 4-associated erbB-2 and phosphoinositide 3-kinase in keratinocyte haptotactic migration dependent on alpha 3 beta 1 integrin. J.Cell. Biol. 2001, 153:465-478.
    • (2001) J.Cell. Biol. , vol.153 , pp. 465-478
    • Hintermann, E.1    Bilban, M.2    Sharabi, A.3    Quaranta, V.4
  • 19
    • 0021993208 scopus 로고
    • Alpha-Difluoromethylornithine inhibits cell growth stimulated by a tumor-promoting rat urinary fraction
    • Homma Y., Ozono S., Numata I., Seidenfeld J., Oyasu R. alpha-Difluoromethylornithine inhibits cell growth stimulated by a tumor-promoting rat urinary fraction. Carcinogenesis 1985, 6:159-161.
    • (1985) Carcinogenesis , vol.6 , pp. 159-161
    • Homma, Y.1    Ozono, S.2    Numata, I.3    Seidenfeld, J.4    Oyasu, R.5
  • 20
    • 58149269633 scopus 로고    scopus 로고
    • The urokinase receptor and its structural homologue C4.4A in human cancer: expression, prognosis and pharmacological inhibition
    • Jacobsen B., Ploug M. The urokinase receptor and its structural homologue C4.4A in human cancer: expression, prognosis and pharmacological inhibition. Curr. Med. Chem. 2008, 15:2559-2573.
    • (2008) Curr. Med. Chem. , vol.15 , pp. 2559-2573
    • Jacobsen, B.1    Ploug, M.2
  • 21
  • 22
    • 79955541291 scopus 로고    scopus 로고
    • CD44v6 coordinates tumor matrix-triggered motility and apoptosis resistance
    • Jung T., Gross W., Zöller M. CD44v6 coordinates tumor matrix-triggered motility and apoptosis resistance. J.Biol. Chem. 2011, 286:15862-15874.
    • (2011) J.Biol. Chem. , vol.286 , pp. 15862-15874
    • Jung, T.1    Gross, W.2    Zöller, M.3
  • 23
    • 73349114294 scopus 로고    scopus 로고
    • Roles of laminin-332 and alpha6beta4 integrin in tumor progression
    • Kariya Y., Kariya Y., Gu J. Roles of laminin-332 and alpha6beta4 integrin in tumor progression. Mini. Rev. Med. Chem. 2009, 9:1284-1291.
    • (2009) Mini. Rev. Med. Chem. , vol.9 , pp. 1284-1291
    • Kariya, Y.1    Kariya, Y.2    Gu, J.3
  • 24
    • 61349189010 scopus 로고    scopus 로고
    • CD44 variant isoforms promote metastasis formation by a tumor cell-matrix cross-talk that supports adhesion and apoptosis resistance
    • Klingbeil P., Marhaba R., Jung T., Kirmse R., Ludwig T., Zöller M. CD44 variant isoforms promote metastasis formation by a tumor cell-matrix cross-talk that supports adhesion and apoptosis resistance. Mol. Cancer Res. 2009, 7:168-179.
    • (2009) Mol. Cancer Res. , vol.7 , pp. 168-179
    • Klingbeil, P.1    Marhaba, R.2    Jung, T.3    Kirmse, R.4    Ludwig, T.5    Zöller, M.6
  • 26
    • 12844275940 scopus 로고    scopus 로고
    • Membrane-type matrix metalloproteinase-1 (MT1-MMP) is a processing enzyme for human laminin gamma 2 chain
    • Koshikawa N., Minegishi T., Sharabi A., Quaranta V., Seiki M. Membrane-type matrix metalloproteinase-1 (MT1-MMP) is a processing enzyme for human laminin gamma 2 chain. J.Biol. Chem. 2005, 280:88-93.
    • (2005) J.Biol. Chem. , vol.280 , pp. 88-93
    • Koshikawa, N.1    Minegishi, T.2    Sharabi, A.3    Quaranta, V.4    Seiki, M.5
  • 27
    • 79953780037 scopus 로고    scopus 로고
    • Expression of C4.4A, a structural uPAR homolog, reflects squamous epithelial differentiation in the adult mouse and during embryogenesis
    • Kriegbaum M.C., Jacobsen B., Hald A., Ploug M. Expression of C4.4A, a structural uPAR homolog, reflects squamous epithelial differentiation in the adult mouse and during embryogenesis. J.Histochem. Cytochem. 2011, 59:188-201.
    • (2011) J.Histochem. Cytochem. , vol.59 , pp. 188-201
    • Kriegbaum, M.C.1    Jacobsen, B.2    Hald, A.3    Ploug, M.4
  • 28
    • 27644496163 scopus 로고    scopus 로고
    • Mobilization and activation of a signaling competent alpha6beta4integrin underlies its contribution to carcinoma progression
    • Lipscomb E.A., Mercurio A.M. Mobilization and activation of a signaling competent alpha6beta4integrin underlies its contribution to carcinoma progression. Cancer Metastasis Rev. 2005, 24:413-423.
    • (2005) Cancer Metastasis Rev. , vol.24 , pp. 413-423
    • Lipscomb, E.A.1    Mercurio, A.M.2
  • 29
    • 34247474890 scopus 로고    scopus 로고
    • Tumour microenvironment: laminin 332 in squamous-cell carcinoma
    • Marinkovich M.P. Tumour microenvironment: laminin 332 in squamous-cell carcinoma. Nat. Rev. Cancer 2007, 7:370-380.
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 370-380
    • Marinkovich, M.P.1
  • 30
    • 0020521439 scopus 로고
    • Characterization of BSp73 a spontaneous rat tumor and its invivo selected variants showing different metastasizing capacities
    • Matzku S., Komitowski D., Mildenberger M., Zöller M. Characterization of BSp73 a spontaneous rat tumor and its invivo selected variants showing different metastasizing capacities. Invasion Metastasis 1983, 3:109-123.
    • (1983) Invasion Metastasis , vol.3 , pp. 109-123
    • Matzku, S.1    Komitowski, D.2    Mildenberger, M.3    Zöller, M.4
  • 31
    • 0035019920 scopus 로고    scopus 로고
    • Towards a mechanistic understanding of tumor invasion-lessons from the alpha6beta 4 integrin
    • Mercurio A.M., Rabinovitz I. Towards a mechanistic understanding of tumor invasion-lessons from the alpha6beta 4 integrin. Semin. Cancer Biol. 2001, 11:129-141.
    • (2001) Semin. Cancer Biol. , vol.11 , pp. 129-141
    • Mercurio, A.M.1    Rabinovitz, I.2
  • 32
    • 35648976145 scopus 로고    scopus 로고
    • Intrinsic signaling functions of the beta4 integrin intracellular domain
    • Merdek K.D., Yang X., Taglienti C.A., Shaw L.M., Mercurio A.M. Intrinsic signaling functions of the beta4 integrin intracellular domain. J.Biol. Chem. 2007, 282:30322-30330.
    • (2007) J.Biol. Chem. , vol.282 , pp. 30322-30330
    • Merdek, K.D.1    Yang, X.2    Taglienti, C.A.3    Shaw, L.M.4    Mercurio, A.M.5
  • 33
    • 85027930332 scopus 로고    scopus 로고
    • Rethinking the metastatic cascade as a therapeutic target
    • Mina L.A., Sledge G.W. Rethinking the metastatic cascade as a therapeutic target. Nat. Rev. Clin. Oncol. 2011, 8:325-332.
    • (2011) Nat. Rev. Clin. Oncol. , vol.8 , pp. 325-332
    • Mina, L.A.1    Sledge, G.W.2
  • 34
    • 84858032415 scopus 로고    scopus 로고
    • Membrane-bound and exosomal metastasis-associated C4.4A promotes migration by associating with the ?(6)?(4) integrin and MT1-MMP
    • Ngora H., Galli U.M., Miyazaki K., Zöller M. Membrane-bound and exosomal metastasis-associated C4.4A promotes migration by associating with the ?(6)?(4) integrin and MT1-MMP. Neoplasia 2012, 14:95-107.
    • (2012) Neoplasia , vol.14 , pp. 95-107
    • Ngora, H.1    Galli, U.M.2    Miyazaki, K.3    Zöller, M.4
  • 35
    • 0033813105 scopus 로고    scopus 로고
    • Deposition of laminin 5 in epidermal wounds regulates integrin signaling and adhesion
    • Nguyen B.P., Ryan M.C., Gil S.G., Carter W.G. Deposition of laminin 5 in epidermal wounds regulates integrin signaling and adhesion. Curr. Opin. Cell. Biol. 2000, 12:554-562.
    • (2000) Curr. Opin. Cell. Biol. , vol.12 , pp. 554-562
    • Nguyen, B.P.1    Ryan, M.C.2    Gil, S.G.3    Carter, W.G.4
  • 36
    • 33744903401 scopus 로고    scopus 로고
    • Tight junction protein claudin-1 enhances the invasive activity of oral squamous cell carcinoma cells by promoting cleavage of laminin-5 gamma2 chain via matrix metalloproteinase (MMP)-2 and membrane-type MMP-1
    • Oku N., Sasabe E., Ueta E., Yamamoto T., Osaki T. Tight junction protein claudin-1 enhances the invasive activity of oral squamous cell carcinoma cells by promoting cleavage of laminin-5 gamma2 chain via matrix metalloproteinase (MMP)-2 and membrane-type MMP-1. Cancer Res. 2006, 66:5251-5257.
    • (2006) Cancer Res. , vol.66 , pp. 5251-5257
    • Oku, N.1    Sasabe, E.2    Ueta, E.3    Yamamoto, T.4    Osaki, T.5
  • 37
    • 20144378201 scopus 로고    scopus 로고
    • Ly6 family member C4.4A binds laminins 1 and 5 associates with galectin-3 and supports cell migration
    • Paret C., Bourouba M., Beer A., Miyazaki K., Schnölzer M., Fiedler S., Zöller M. Ly6 family member C4.4A binds laminins 1 and 5 associates with galectin-3 and supports cell migration. Int. J. Cancer 2005, 115:724-733.
    • (2005) Int. J. Cancer , vol.115 , pp. 724-733
    • Paret, C.1    Bourouba, M.2    Beer, A.3    Miyazaki, K.4    Schnölzer, M.5    Fiedler, S.6    Zöller, M.7
  • 39
    • 33750514792 scopus 로고    scopus 로고
    • Beta4 integrin and epidermal growth factor coordinately regulate electric field-mediated directional migration via Rac1
    • Pullar C.E., Baier B.S., Kariya Y., Russell A.J., Horst B.A., Marinkovich M.P., Isseroff R.R. beta4 integrin and epidermal growth factor coordinately regulate electric field-mediated directional migration via Rac1. Mol. Biol. Cell. 2006, 17:4925-4935.
    • (2006) Mol. Biol. Cell. , vol.17 , pp. 4925-4935
    • Pullar, C.E.1    Baier, B.S.2    Kariya, Y.3    Russell, A.J.4    Horst, B.A.5    Marinkovich, M.P.6    Isseroff, R.R.7
  • 40
    • 0032532535 scopus 로고    scopus 로고
    • Cloning and functional characterization of a new phosphatidyl-inositol anchored molecule of a metastasizing rat pancreatic tumor
    • Rösel M., Claas C., Seiter S., Herlevsen M., Zöller M. Cloning and functional characterization of a new phosphatidyl-inositol anchored molecule of a metastasizing rat pancreatic tumor. Oncogene 1998, 17:1989-2002.
    • (1998) Oncogene , vol.17 , pp. 1989-2002
    • Rösel, M.1    Claas, C.2    Seiter, S.3    Herlevsen, M.4    Zöller, M.5
  • 43
    • 0034951677 scopus 로고    scopus 로고
    • Identification of insulin receptor substrate 1 (IRS-1) and IRS-2 as signaling intermediates in the alpha6beta4 integrin-dependent activation of phosphoinositide 3-OH kinase and promotion of invasion
    • Shaw L.M. Identification of insulin receptor substrate 1 (IRS-1) and IRS-2 as signaling intermediates in the alpha6beta4 integrin-dependent activation of phosphoinositide 3-OH kinase and promotion of invasion. Mol. Cell. Biol. 2001, 21:5082-5093.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 5082-5093
    • Shaw, L.M.1
  • 44
    • 0035866405 scopus 로고    scopus 로고
    • Identification of genes involved in human urothelial cell-matrix interactions: implications for the progression pathways of malignant urothelium
    • Smith B.A., Kennedy W.J., Harnden P., Selby P.J., Trejdosiewicz L.K., Southgate J. Identification of genes involved in human urothelial cell-matrix interactions: implications for the progression pathways of malignant urothelium. Cancer Res. 2001, 61:1678-1685.
    • (2001) Cancer Res. , vol.61 , pp. 1678-1685
    • Smith, B.A.1    Kennedy, W.J.2    Harnden, P.3    Selby, P.J.4    Trejdosiewicz, L.K.5    Southgate, J.6
  • 45
    • 79955073961 scopus 로고    scopus 로고
    • Lipid rafts: signaling and sorting platforms of cells and their roles in cancer
    • Staubach S., Hanisch F.G. Lipid rafts: signaling and sorting platforms of cells and their roles in cancer. Expert Rev. Proteom. 2011, 8:263-277.
    • (2011) Expert Rev. Proteom. , vol.8 , pp. 263-277
    • Staubach, S.1    Hanisch, F.G.2
  • 46
    • 84860389354 scopus 로고    scopus 로고
    • Deciphering the rules of programmed cell death to improve therapy of cancer and other diseases
    • Strasser A., Cory S., Adams J.M. Deciphering the rules of programmed cell death to improve therapy of cancer and other diseases. EMBO J. 2011, 30:3667-3683.
    • (2011) EMBO J. , vol.30 , pp. 3667-3683
    • Strasser, A.1    Cory, S.2    Adams, J.M.3
  • 47
    • 62149091091 scopus 로고    scopus 로고
    • Signal co-operation between integrins and other receptor systems
    • Streuli C.H., Akhtar N. Signal co-operation between integrins and other receptor systems. Biochem. J. 2009, 418:491-506.
    • (2009) Biochem. J. , vol.418 , pp. 491-506
    • Streuli, C.H.1    Akhtar, N.2
  • 48
    • 0035977147 scopus 로고    scopus 로고
    • A signaling adapter function for alpha6beta4 integrin in the control of HGF-dependent invasive growth
    • Trusolino L., Bertotti A., Comoglio P.M. A signaling adapter function for alpha6beta4 integrin in the control of HGF-dependent invasive growth. Cell 2001, 107:643-654.
    • (2001) Cell , vol.107 , pp. 643-654
    • Trusolino, L.1    Bertotti, A.2    Comoglio, P.M.3
  • 49
    • 0038713422 scopus 로고    scopus 로고
    • Bowden GT. Membrane type-1-matrix metalloproteinase expressed by prostate carcinoma cells cleaves human laminin-5 beta3 chain and induces cell migration
    • Udayakumar T.S., Chen M.L., Bair E.L., VonBredow D.C., Cress A.E., Nagle R.B. Bowden GT. Membrane type-1-matrix metalloproteinase expressed by prostate carcinoma cells cleaves human laminin-5 beta3 chain and induces cell migration. Cancer Res. 2003, 63:2292-2299.
    • (2003) Cancer Res. , vol.63 , pp. 2292-2299
    • Udayakumar, T.S.1    Chen, M.L.2    Bair, E.L.3    VonBredow, D.C.4    Cress, A.E.5    Nagle, R.B.6
  • 50
    • 33745792550 scopus 로고    scopus 로고
    • Expression and diagnostic application of C4.4A protein in squamous cell carcinoma and adenocarcinoma
    • Wang W., Ding Y.Q., Li Z.G., Han H.X., Yang L. Expression and diagnostic application of C4.4A protein in squamous cell carcinoma and adenocarcinoma. Zhonghua Bing Li Xue Za Zhi 2006, 35:277-280.
    • (2006) Zhonghua Bing Li Xue Za Zhi , vol.35 , pp. 277-280
    • Wang, W.1    Ding, Y.Q.2    Li, Z.G.3    Han, H.X.4    Yang, L.5
  • 51
    • 33645837225 scopus 로고    scopus 로고
    • Multiple functions of the integrin alpha6beta4 in epidermal homeostasis and tumorigenesis
    • Wilhelmsen K., Litjens S.H., Sonnenberg A. Multiple functions of the integrin alpha6beta4 in epidermal homeostasis and tumorigenesis. Mol. Cell. Biol. 2006, 26:2877-2886.
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 2877-2886
    • Wilhelmsen, K.1    Litjens, S.H.2    Sonnenberg, A.3
  • 54
    • 78649615616 scopus 로고    scopus 로고
    • SHP2 mediates the localized activation of Fyn downstream of the α6β4 integrin to promote carcinoma invasion
    • Yang X., Dutta U., Shaw L.M. SHP2 mediates the localized activation of Fyn downstream of the α6β4 integrin to promote carcinoma invasion. Mol. Cell. Biol. 2010, 30:5306-5317.
    • (2010) Mol. Cell. Biol. , vol.30 , pp. 5306-5317
    • Yang, X.1    Dutta, U.2    Shaw, L.M.3
  • 55
    • 11244304502 scopus 로고    scopus 로고
    • Palmitoylation supports assembly and function of integrin-tetraspanin complexes
    • Yang X., Kovalenko O.V., Tang W., Claas C., Stipp C.S., Hemler M.E. Palmitoylation supports assembly and function of integrin-tetraspanin complexes. J.Cell. Biol. 2004, 167:1231-1240.
    • (2004) J.Cell. Biol. , vol.167 , pp. 1231-1240
    • Yang, X.1    Kovalenko, O.V.2    Tang, W.3    Claas, C.4    Stipp, C.S.5    Hemler, M.E.6
  • 56
    • 65349107367 scopus 로고    scopus 로고
    • CCAAT/enhancer-binding protein beta: its role in breast cancer and associations with receptor tyrosine kinases
    • Zahnow C.A. CCAAT/enhancer-binding protein beta: its role in breast cancer and associations with receptor tyrosine kinases. Expert Rev. Mol. Med. 2009, 11:e12.
    • (2009) Expert Rev. Mol. Med. , vol.11
    • Zahnow, C.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.