Effect of JGK-263 as a new glycogen synthase kinase-3β inhibitor on extrinsic apoptosis pathway in motor neuronal cells

Biochemical and Biophysical Research Communications

Volumn 439, Issue 2, 2013, Pages 309-314

  Jeon, Gye Sun ^a   Kim, Jee Eun ^b   Ahn, Suk Won ^c   Park, Kyung Seok ^d   Hong, Yoon Ho ^e   Ye, In Hae ^f   Park, Ji Seon ^f   Kim, Seung Hyun ^g   Lee, Kwang Woo ^a   Kim, Sung Min ^a   Sung, Jung Joon ^a  

^a Seoul National University Hospital   (South Korea)

^b Seoul Medical Center   (South Korea)

^c Chung Ang University   (South Korea)

^d Seoul National University Bundang Hospital   (South Korea)

^e Seoul National University Boramae Hospital   (South Korea)

^f Jeil Pharmaceutical Co Ltd   (South Korea)

^g Hanyang University   (South Korea)

Author keywords

Amyotrophic lateral sclerosis; Extrinsic apoptosis; Glycogen synthase kinase 3; JGK 263; Motor neuron

Indexed keywords

CASPASE 8; CYTOCHROME C; DAXX PROTEIN; ENZYME INHIBITOR; FAS ANTIGEN; FAS LIGAND; GLYCOGEN SYNTHASE KINASE 3BETA; JGK 263; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DRUG MEGADOSE; MOTONEURON; MOUSE; NERVE CELL DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION;

AMYOTROPHIC LATERAL SCLEROSIS; EXTRINSIC APOPTOSIS; GLYCOGEN SYNTHASE KINASE-3; JGK-263; MOTOR NEURON;

ANIMALS; APOPTOSIS; CELL LINE; CELL SURVIVAL; GLYCOGEN SYNTHASE KINASE 3; MICE; MOTOR NEURONS; PROTEIN KINASE INHIBITORS; SIGNAL TRANSDUCTION;

EID: 84884283841     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.07.080     Document Type: Article

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