Selectivity data: Assessment, predictions, concordance, and implications

Journal of Medicinal Chemistry

Volumn 56, Issue 17, 2013, Pages 6991-7002

  Gao, Cen ^a   Cahya, Suntara ^a   Nicolaou, Christos A ^a   Wang, Jibo ^a   Watson, Ian A ^a   Cummins, David J ^a   Iversen, Philip W ^a   Vieth, Michal ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 (1 CYANO 1 METHYLETHYL) 3 METHYL 8 (3 QUINOLINYL)IMIDAZO[4,5 C]QUINOLIN 2(1H,3H) ONE; 4 [[9 CHLORO 7 (2,6 DIFLUOROPHENYL) 5H PYRIMIDO[5,4 D][2]BENZAZEPIN 2 YL]AMINO]BENZOIC ACID; 5 (2,6 DICHLOROPHENYL) 2 (2,4 DIFLUOROPHENYLTHIO)PYRIMIDO[1,6 B]PYRIDAZIN 6 ONE; ALISERTIB; AST 487; BARASERTIB; CRIZOTINIB; CYC 116; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 5; CYCLIN DEPENDENT KINASE 6; CYCLIN DEPENDENT KINASE 9; DANUSERTIB; DASATINIB; DORAMAPIMOD; DOVITINIB; ERLOTINIB; FLT3 LIGAND; IMATINIB; JNJ 7706621; LINIFANIB; MK 1175; PALBOCICLIB; PAZOPANIB; PF 04217903; PF 562271; SOTRASTAURIN; TAE 684; TOZASERTIB; UNCLASSIFIED DRUG; VATALANIB;

ARTICLE; COMPUTER MODEL; DATA ANALYSIS; ELECTRON; IC 50; PHYLOGENETIC TREE; PREDICTION; RANDOM FOREST; SUPPORT VECTOR MACHINE; UNCERTAINTY;

COMPUTER SIMULATION; DRUG DISCOVERY;

EID: 84884276795     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm400798j     Document Type: Article

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