메뉴 건너뛰기




Volumn 13, Issue 11, 1998, Pages 1660-1667

Molecular mechanism of action of fluoride on bone cells

Author keywords

[No Author keywords available]

Indexed keywords

FLUORIDE; GUANINE NUCLEOTIDE BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN TYROSINE PHOSPHATASE; RAF PROTEIN; RAS PROTEIN;

EID: 0031722817     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.1998.13.11.1660     Document Type: Review
Times cited : (117)

References (67)
  • 1
    • 84944969854 scopus 로고
    • Treatment of primary osteoporosis with fluoride and calcium: Clinical tolerance and fracture occurrence
    • Riggs BL, Hodgson SF, Hoffman DL, Kelly PJ, Johnson KA, Taves DR 1980 Treatment of primary osteoporosis with fluoride and calcium: Clinical tolerance and fracture occurrence. J Am Med Assoc 243:446-449.
    • (1980) J Am Med Assoc , vol.243 , pp. 446-449
    • Riggs, B.L.1    Hodgson, S.F.2    Hoffman, D.L.3    Kelly, P.J.4    Johnson, K.A.5    Taves, D.R.6
  • 2
    • 0019817871 scopus 로고
    • Treatment of osteoporosis with fluoride, calcium, and vitamin D
    • Briancon D, Meunier PJ 1981 Treatment of osteoporosis with fluoride, calcium, and vitamin D. Orthop Clin North Am 12: 629-648.
    • (1981) Orthop Clin North Am , vol.12 , pp. 629-648
    • Briancon, D.1    Meunier, P.J.2
  • 8
    • 0029090252 scopus 로고
    • Treatment of postmenopausal osteoporosis with slow-release sodium fluoride: Final report of a randomized controlled trial
    • Pak CYC, Sakhaee K, Adams-Huet B, Piziak V, Peterson RD, Poindexter JR 1995 Treatment of postmenopausal osteoporosis with slow-release sodium fluoride: Final report of a randomized controlled trial. Ann Intern Med 123:401-408.
    • (1995) Ann Intern Med , vol.123 , pp. 401-408
    • Pak, C.Y.C.1    Sakhaee, K.2    Adams-Huet, B.3    Piziak, V.4    Peterson, R.D.5    Poindexter, J.R.6
  • 9
    • 85055182694 scopus 로고    scopus 로고
    • Osteogenic actions of fluoride: Its therapeutic use for established osteoporosis
    • Whitfield JF, Morley P (eds.) CRC Press Inc., Boca Raton, FL, U.S.A.
    • Lau K-HW, Åkesson K, Libanati CR, Baylink DJ 1998 Osteogenic actions of fluoride: Its therapeutic use for established osteoporosis. In: Whitfield JF, Morley P (eds.) Anabolic Treatments for Osteoporosis. CRC Press Inc., Boca Raton, FL, U.S.A., pp. 207-254.
    • (1998) Anabolic Treatments for Osteoporosis , pp. 207-254
    • Lau, K.-H.W.1    Åkesson, K.2    Libanati, C.R.3    Baylink, D.J.4
  • 10
    • 0020619183 scopus 로고
    • Fluoride directly stimulates proliferation and alkaline phosphatase activity of bone forming cells
    • Farley JR, Wergedal JR, Baylink DJ 1983 Fluoride directly stimulates proliferation and alkaline phosphatase activity of bone forming cells. Science 222:330-332.
    • (1983) Science , vol.222 , pp. 330-332
    • Farley, J.R.1    Wergedal, J.R.2    Baylink, D.J.3
  • 12
    • 0023275158 scopus 로고
    • Sodium fluoride as an initiator of osteogenesis from embryonic mesenchyme in vitro
    • Hall BK 1987 Sodium fluoride as an initiator of osteogenesis from embryonic mesenchyme in vitro. Bone 8:111-116.
    • (1987) Bone , vol.8 , pp. 111-116
    • Hall, B.K.1
  • 13
    • 0023682176 scopus 로고
    • Fluoride and bovine bone extract influence cell proliferation and phosphatase activities in human bone cell cultures
    • Wergedal JE, Lau K-HW, Baylink DJ 1988 Fluoride and bovine bone extract influence cell proliferation and phosphatase activities in human bone cell cultures. Clin Orthop 233: 274-282.
    • (1988) Clin Orthop , vol.233 , pp. 274-282
    • Wergedal, J.E.1    Lau, K.-H.W.2    Baylink, D.J.3
  • 14
    • 0025514281 scopus 로고
    • 3H-thymidine incorporation and alkaline phosphatase production by human osteoblasts
    • 3H-thymidine incorporation and alkaline phosphatase production by human osteoblasts. Metabolism 39:1118-1121.
    • (1990) Metabolism , vol.39 , pp. 1118-1121
    • Khokher, M.A.1    Dandona, P.2
  • 15
    • 0025779218 scopus 로고
    • Aluminum stimulates the proliferation and differentiation of osteoblasts in vitro by a mechanism that is different from fluoride
    • Lau K-HW, Yoo A, Wang SP 1991 Aluminum stimulates the proliferation and differentiation of osteoblasts in vitro by a mechanism that is different from fluoride. Mol Cell Biochem 105:93-105.
    • (1991) Mol Cell Biochem , vol.105 , pp. 93-105
    • Lau, K.-H.W.1    Yoo, A.2    Wang, S.P.3
  • 17
    • 0027442745 scopus 로고
    • Differential effects of fluoride during initiation and progression of mineralization of osteoid nodules formed in vitro
    • Bellows CG, Aubin JE, Heersche JNM 1993 Differential effects of fluoride during initiation and progression of mineralization of osteoid nodules formed in vitro. J Bone Miner Res 8:1357-1363.
    • (1993) J Bone Miner Res , vol.8 , pp. 1357-1363
    • Bellows, C.G.1    Aubin, J.E.2    Heersche, J.N.M.3
  • 18
    • 0027445827 scopus 로고
    • 3 potentiates fluoride-stimulated collagen type I production in cultures on human bone marrow stromal osteoblast-like cells
    • 3 potentiates fluoride-stimulated collagen type I production in cultures on human bone marrow stromal osteoblast-like cells. J Bone Miner Res 8:1453-1458.
    • (1993) J Bone Miner Res , vol.8 , pp. 1453-1458
    • Kassem, M.1    Mosekilde, L.2    Eriksen, E.F.3
  • 19
    • 0027339772 scopus 로고
    • 3H]thymidine uptake in a human osteoblastic osteosarcoma cell line is dependent on transforming growth factor β
    • 3H]thymidine uptake in a human osteoblastic osteosarcoma cell line is dependent on transforming growth factor β. J Bone Miner Res 8:19-25.
    • (1993) J Bone Miner Res , vol.8 , pp. 19-25
    • Reed, B.Y.1    Zerwekh, J.E.2    Antich, P.P.3    Pak, C.Y.C.4
  • 20
    • 0028930242 scopus 로고
    • Fluoride increases tyrosine kinase activity in osteoblast-like cells: Regulatory role for the stimulation of cell proliferation and Pi transport across the plasma membrane
    • Burgener D, Bonjour JP, Caverzasio J 1995 Fluoride increases tyrosine kinase activity in osteoblast-like cells: Regulatory role for the stimulation of cell proliferation and Pi transport across the plasma membrane. J Bone Miner Res 10:164-171.
    • (1995) J Bone Miner Res , vol.10 , pp. 164-171
    • Burgener, D.1    Bonjour, J.P.2    Caverzasio, J.3
  • 21
    • 0028269558 scopus 로고
    • Effects of fluoride on human bone cells in vitro: Differences in responsiveness between stromal osteoblast precursors and mature osteoblasts
    • Kassem M, Mosekilde L, Eriksen EF 1994 Effects of fluoride on human bone cells in vitro: Differences in responsiveness between stromal osteoblast precursors and mature osteoblasts. Acta Endocrinol 130:381-386.
    • (1994) Acta Endocrinol , vol.130 , pp. 381-386
    • Kassem, M.1    Mosekilde, L.2    Eriksen, E.F.3
  • 23
    • 0024988967 scopus 로고
    • Fluoride rapidly and transiently raises intracellular Ca in human osteoblasts
    • Zerwekh J, Morris A, Padalino P, Gottschalk F, Pak CYC 1990 Fluoride rapidly and transiently raises intracellular Ca in human osteoblasts. J Bone Miner Res 5 (Suppl 1):S131-S136.
    • (1990) J Bone Miner Res , vol.5 , Issue.1 SUPPL.
    • Zerwekh, J.1    Morris, A.2    Padalino, P.3    Gottschalk, F.4    Pak, C.Y.C.5
  • 24
    • 0025873409 scopus 로고
    • Fluoride selectively stimulates Na-dependent phosphate transport in osteoblast-like cells
    • Selz T, Caverzasio J, Bonjour J-P 1991 Fluoride selectively stimulates Na-dependent phosphate transport in osteoblast-like cells. Am J Physiol 260:E833-E838.
    • (1991) Am J Physiol , vol.260
    • Selz, T.1    Caverzasio, J.2    Bonjour, J.-P.3
  • 25
    • 0023779925 scopus 로고
    • 3H]thymidine incorporation in embryonic chick calvarial cell cultures is dependent on the presence of a bone mitogen, sensitive to changes in the phosphate concentration, and modulated by systemic skeletal effectors
    • 3H]thymidine incorporation in embryonic chick calvarial cell cultures is dependent on the presence of a bone mitogen, sensitive to changes in the phosphate concentration, and modulated by systemic skeletal effectors. Metabolism 37:988-995.
    • (1988) Metabolism , vol.37 , pp. 988-995
    • Farley, J.R.1    Tarbaux, N.2    Hall, S.3    Baylink, D.J.4
  • 26
    • 0025024029 scopus 로고
    • The effects of fluoride on osteoblast progenitors in vitro
    • Bellows CG, Heersche JNM, Aubin JE 1990 The effects of fluoride on osteoblast progenitors in vitro. J Bone Miner Res 5 (Suppl 1):S101-S105.
    • (1990) J Bone Miner Res , vol.5 , Issue.1 SUPPL.
    • Bellows, C.G.1    Heersche, J.N.M.2    Aubin, J.E.3
  • 27
    • 0025161364 scopus 로고
    • Mitogenic action(s) of fluoride on osteoblast line cells: Determinants of the response in vitro
    • Farley JR, Tarbaux N, Hall S, Baylink DJ 1990 Mitogenic action(s) of fluoride on osteoblast line cells: Determinants of the response in vitro. J Bone Miner Res 5 (Suppl 1):S107-S113.
    • (1990) J Bone Miner Res , vol.5 , Issue.1 SUPPL.
    • Farley, J.R.1    Tarbaux, N.2    Hall, S.3    Baylink, D.J.4
  • 29
    • 0024462841 scopus 로고
    • A proposed mechanism of the mitogenic action of fluoride on bone cells: Inhibition of the activity of an osteoblastic acid phosphatase
    • Lau K-HW, Farley JR, Freeman TK, Baylink DJ 1989 A proposed mechanism of the mitogenic action of fluoride on bone cells: inhibition of the activity of an osteoblastic acid phosphatase. Metabolism 38:858-868.
    • (1989) Metabolism , vol.38 , pp. 858-868
    • Lau, K.-H.W.1    Farley, J.R.2    Freeman, T.K.3    Baylink, D.J.4
  • 30
    • 0030015184 scopus 로고    scopus 로고
    • Fluoride at mitogenic concentrations increases the steady state phosphotyrosyl phosphorylation level of cellular proteins in human bone cells
    • Thomas AB, Hashimoto H, Baylink DJ, Lau K-HW 1996 Fluoride at mitogenic concentrations increases the steady state phosphotyrosyl phosphorylation level of cellular proteins in human bone cells. J Clin Endocrinol Metab 81:2570-2578.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 2570-2578
    • Thomas, A.B.1    Hashimoto, H.2    Baylink, D.J.3    Lau, K.-H.W.4
  • 32
    • 0025343230 scopus 로고
    • Signal transduction by receptors with tyrosine kinase activity
    • Ullrich A, Schlessinger J 1990 Signal transduction by receptors with tyrosine kinase activity. Cell 61:203-212.
    • (1990) Cell , vol.61 , pp. 203-212
    • Ullrich, A.1    Schlessinger, J.2
  • 36
    • 0001010670 scopus 로고
    • Signal transduction from membrane to cytoplasm: Growth factors and membrane-bound oncogene products increase Raf-1 phosphorylation and associated protein kinase activity
    • Morrison DK, Kaplan DR, Rapp U, Roberts TM 1988 Signal transduction from membrane to cytoplasm: Growth factors and membrane-bound oncogene products increase Raf-1 phosphorylation and associated protein kinase activity. Proc Natl Acad Sci USA 85:8855-8859.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 8855-8859
    • Morrison, D.K.1    Kaplan, D.R.2    Rapp, U.3    Roberts, T.M.4
  • 37
    • 0025177324 scopus 로고
    • Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases
    • Ellis C, Moran M, McCormick F, Pawson T 1990 Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases. Nature 343:377-381.
    • (1990) Nature , vol.343 , pp. 377-381
    • Ellis, C.1    Moran, M.2    McCormick, F.3    Pawson, T.4
  • 40
    • 0026587013 scopus 로고
    • Transmembrane receptors and intracellular pathways that control cell proliferation
    • Pouyssegur J, Seuwen K 1992 Transmembrane receptors and intracellular pathways that control cell proliferation. Annu Rev Physiol 54:195-210.
    • (1992) Annu Rev Physiol , vol.54 , pp. 195-210
    • Pouyssegur, J.1    Seuwen, K.2
  • 42
    • 0026695645 scopus 로고
    • TCF by MAP kinase stimulates ternary complex formation at c-fos promoter
    • TCF by MAP kinase stimulates ternary complex formation at c-fos promoter. Nature 358:414-416.
    • (1992) Nature , vol.358 , pp. 414-416
    • Gille, H.1    Sharrocks, A.D.2    Shaw, P.E.3
  • 43
    • 0021808271 scopus 로고
    • Phosphotyrosyl specific protein phosphatase activity of a bovine skeletal acid phosphatase isoenzyme: Comparison with the phosphotyrosyl protein phosphatase activity of skeletal alkaline phosphatase
    • Lau K-HW, Farley JR, Baylink DJ 1985 Phosphotyrosyl specific protein phosphatase activity of a bovine skeletal acid phosphatase isoenzyme: Comparison with the phosphotyrosyl protein phosphatase activity of skeletal alkaline phosphatase. J Biol Chem 260:4653-4660.
    • (1985) J Biol Chem , vol.260 , pp. 4653-4660
    • Lau, K.-H.W.1    Farley, J.R.2    Baylink, D.J.3
  • 44
    • 0023103333 scopus 로고
    • Purification and characterization of a tartrate-resistant acid phosphatase that displays phosphotyrosyl protein phosphatase activity from bovine cortical bone matrix
    • Lau K-HW, Freeman TK, Baylink DJ 1987 Purification and characterization of a tartrate-resistant acid phosphatase that displays phosphotyrosyl protein phosphatase activity from bovine cortical bone matrix. J Biol Chem 262:1389-1397.
    • (1987) J Biol Chem , vol.262 , pp. 1389-1397
    • Lau, K.-H.W.1    Freeman, T.K.2    Baylink, D.J.3
  • 45
  • 46
    • 0026542592 scopus 로고
    • Human bone cells contain a fluoride-sensitive acid phosphatase: Evidence that this enzyme functions at neutral pH as a phosphotyrosyl protein phosphatase
    • Wergedal JW, Lau K-HW 1992 Human bone cells contain a fluoride-sensitive acid phosphatase: Evidence that this enzyme functions at neutral pH as a phosphotyrosyl protein phosphatase. Clin Biochem 25:47-53.
    • (1992) Clin Biochem , vol.25 , pp. 47-53
    • Wergedal, J.W.1    Lau, K.-H.W.2
  • 47
    • 0025297181 scopus 로고
    • A novel magnesium-dependent mechanism for the activation of transduction by fluoride
    • Antonny B, Bigay J, Chabre M 1990 A novel magnesium-dependent mechanism for the activation of transduction by fluoride. FEBS Lett 268:277-280.
    • (1990) FEBS Lett , vol.268 , pp. 277-280
    • Antonny, B.1    Bigay, J.2    Chabre, M.3
  • 48
    • 0024212848 scopus 로고
    • Vanadate stimulates bone cell proliferation and bone collagen synthesis in vitro
    • Lau K-HW, Tanimoto H, Baylink DJ 1988 Vanadate stimulates bone cell proliferation and bone collagen synthesis in vitro. Endocrinology 123:2858-2867.
    • (1988) Endocrinology , vol.123 , pp. 2858-2867
    • Lau, K.-H.W.1    Tanimoto, H.2    Baylink, D.J.3
  • 49
    • 0027350024 scopus 로고
    • Phosphotyrosyl protein phosphatases: Potential regulators of cell proliferation and differentiation
    • Lau K-HW, Baylink DJ 1993 Phosphotyrosyl protein phosphatases: Potential regulators of cell proliferation and differentiation. Crit Rev Oncog 4:451-471.
    • (1993) Crit Rev Oncog , vol.4 , pp. 451-471
    • Lau, K.-H.W.1    Baylink, D.J.2
  • 50
    • 3643082065 scopus 로고
    • Mitogenic action of fluoride on human bone cells is mediated through a sustained activation of the ras-Raf-MAPK signal transduction pathway by inhibition of phosphotyrosyl phosphatase activities
    • abstract 2996
    • Lau K-HW, Wu L-W, Baylink DJ 1995 Mitogenic action of fluoride on human bone cells is mediated through a sustained activation of the ras-Raf-MAPK signal transduction pathway by inhibition of phosphotyrosyl phosphatase activities. FASEB J 10:A1519 (abstract 2996).
    • (1995) FASEB J , vol.10
    • Lau, K.-H.W.1    Wu, L.-W.2    Baylink, D.J.3
  • 51
    • 3643111144 scopus 로고
    • Inhibition of tyrosyl phosphatases stimulates proliferation differentiation: Dependence of proliferation but not differentiation on tyrosyl kinase
    • abstract M228
    • Yoon HK, Baylink DJ, Lau K-HW 1995 Inhibition of tyrosyl phosphatases stimulates proliferation differentiation: Dependence of proliferation but not differentiation on tyrosyl kinase. J Bone Miner Res 10 (Suppl 1):S309 (abstract M228).
    • (1995) J Bone Miner Res , vol.10 , Issue.1 SUPPL.
    • Yoon, H.K.1    Baylink, D.J.2    Lau, K.-H.W.3
  • 52
    • 0030028438 scopus 로고    scopus 로고
    • Aluminum potentiates the effect of fluoride on tyrosine phosphorylation and osteoblast replication in vitro and bone mass in vivo
    • Caverzasio J, Imai T, Ammann P, Burgener D, Bonjour J-P 1996 Aluminum potentiates the effect of fluoride on tyrosine phosphorylation and osteoblast replication in vitro and bone mass in vivo. J Bone Miner Res 11:46-55.
    • (1996) J Bone Miner Res , vol.11 , pp. 46-55
    • Caverzasio, J.1    Imai, T.2    Ammann, P.3    Burgener, D.4    Bonjour, J.-P.5
  • 53
    • 0030786688 scopus 로고    scopus 로고
    • Mechanism of the mitogenic effect of fluoride on osteoblast-like cells: Evidence for a G protein-dependent tyrosine phosphorylation process
    • Caverzasio J, Palmer G, Suzuki A, Bonjour J-P 1997 Mechanism of the mitogenic effect of fluoride on osteoblast-like cells: Evidence for a G protein-dependent tyrosine phosphorylation process. J Bone Miner Res 12:1975-1983.
    • (1997) J Bone Miner Res , vol.12 , pp. 1975-1983
    • Caverzasio, J.1    Palmer, G.2    Suzuki, A.3    Bonjour, J.-P.4
  • 54
    • 0031051444 scopus 로고    scopus 로고
    • Signalling functions and biochemical properties of pertussis toxin-resistant G-proteins
    • Fields TA, Casey PJ 1997 Signalling functions and biochemical properties of pertussis toxin-resistant G-proteins. Biochem J 321:561-571.
    • (1997) Biochem J , vol.321 , pp. 561-571
    • Fields, T.A.1    Casey, P.J.2
  • 56
    • 0024841008 scopus 로고
    • Effects of the tyrosine-kinase inhibitor genistein on DNA synthesis and phospholipid-derived second messenger generation in mouse 10T1/2 fibroblasts and rat liver T51B cells
    • Dean NM, Kanemitsu M, Boynton AL 1989 Effects of the tyrosine-kinase inhibitor genistein on DNA synthesis and phospholipid-derived second messenger generation in mouse 10T1/2 fibroblasts and rat liver T51B cells. Biochem Biophys Res Commun 165:795-801.
    • (1989) Biochem Biophys Res Commun , vol.165 , pp. 795-801
    • Dean, N.M.1    Kanemitsu, M.2    Boynton, A.L.3
  • 57
    • 0026101639 scopus 로고
    • Evidence that genistein, a protein-tyrosine kinase inhibitor, inhibits CD28 monoclonal-antibody-stimulated human T cell proliferation
    • Atluru S, Atluru D 1991 Evidence that genistein, a protein-tyrosine kinase inhibitor, inhibits CD28 monoclonal-antibody-stimulated human T cell proliferation. Transplanation 51:448-450.
    • (1991) Transplanation , vol.51 , pp. 448-450
    • Atluru, S.1    Atluru, D.2
  • 58
    • 3643115385 scopus 로고    scopus 로고
    • Evidence that the mitogenic action of fluoride (F) on human bone cells is mediated by F ion and not by the aluminum fluoride complex
    • abstract T347
    • Hashimoto H, Baylink DJ, Lau K-HW 1997 Evidence that the mitogenic action of fluoride (F) on human bone cells is mediated by F ion and not by the aluminum fluoride complex. J Bone Miner Res 12 (Suppl 1):S188 (abstract T347).
    • (1997) J Bone Miner Res , vol.12 , Issue.1 SUPPL.
    • Hashimoto, H.1    Baylink, D.J.2    Lau, K.-H.W.3
  • 59
    • 0028134705 scopus 로고
    • The somatostatin receptor SSTR1 is coupled to phosphotyrosine phosphatase activity in CHO-K1 cells
    • Florio T, Rim C, Hershberger RE, Loda M, Stork PJ 1994 The somatostatin receptor SSTR1 is coupled to phosphotyrosine phosphatase activity in CHO-K1 cells. Mol Endocrinol 8: 1289-1297.
    • (1994) Mol Endocrinol , vol.8 , pp. 1289-1297
    • Florio, T.1    Rim, C.2    Hershberger, R.E.3    Loda, M.4    Stork, P.J.5
  • 60
    • 0030936370 scopus 로고    scopus 로고
    • Protein-tyrosine phosphatase SHP2 is positively linked to proteinase-activated receptor 2-mediated mitogenic pathway
    • Yu Z, Ahmad S, Schwartz JL, Banville D, Shen SH 1997 Protein-tyrosine phosphatase SHP2 is positively linked to proteinase-activated receptor 2-mediated mitogenic pathway. J Biol Chem 272:7519-7524.
    • (1997) J Biol Chem , vol.272 , pp. 7519-7524
    • Yu, Z.1    Ahmad, S.2    Schwartz, J.L.3    Banville, D.4    Shen, S.H.5
  • 61
    • 0029816592 scopus 로고    scopus 로고
    • Coupling of gonadotropin-releasing hormone receptor to Gi protein in human reproductive tract tumors
    • Imai A, Takagi H, Horibe S, Fuseya T, Tamaya T 1996 Coupling of gonadotropin-releasing hormone receptor to Gi protein in human reproductive tract tumors. J Clin Endocrinol Metab 81:3249-3253.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 3249-3253
    • Imai, A.1    Takagi, H.2    Horibe, S.3    Fuseya, T.4    Tamaya, T.5
  • 62
    • 9444242667 scopus 로고    scopus 로고
    • G-protein βγ subunits mediate specific phosphorylation of the protein-tyrosine phosphatase SH-PTP1 induced by lysophosphatidic acid
    • Gaits F, Li RY, Bigay J, Ragab A, Ragab-Thomas MF, Chap H 1996 G-protein βγ subunits mediate specific phosphorylation of the protein-tyrosine phosphatase SH-PTP1 induced by lysophosphatidic acid. J Biol Chem 271:20151-20155.
    • (1996) J Biol Chem , vol.271 , pp. 20151-20155
    • Gaits, F.1    Li, R.Y.2    Bigay, J.3    Ragab, A.4    Ragab-Thomas, M.F.5    Chap, H.6
  • 65
    • 0029884056 scopus 로고    scopus 로고
    • Angiotensin II stimulates protein phosphatase 2A activity in cultured neuronal cells via type 2 receptors in a pertussis toxin sensitive fashion
    • Huang XC, Sumners C, Richards EM 1996 Angiotensin II stimulates protein phosphatase 2A activity in cultured neuronal cells via type 2 receptors in a pertussis toxin sensitive fashion. Adv Exp Med Biol 396:209-215.
    • (1996) Adv Exp Med Biol , vol.396 , pp. 209-215
    • Huang, X.C.1    Sumners, C.2    Richards, E.M.3
  • 66
    • 0024307065 scopus 로고
    • Studies on the transmembrane migration of fluoride and its effects on proliferation of L-929 fibroblasts (L cells) in vitro
    • Kawase T, Suzuki A 1989 Studies on the transmembrane migration of fluoride and its effects on proliferation of L-929 fibroblasts (L cells) in vitro. Arch Oral Biol 34:103-107.
    • (1989) Arch Oral Biol , vol.34 , pp. 103-107
    • Kawase, T.1    Suzuki, A.2
  • 67
    • 0029913537 scopus 로고    scopus 로고
    • Role of protein kinase Cα, Arf, and cytoplasmic calcium transient in phospholipase D activation by sodium fluoride in osteoblast-like cells
    • Bourgoin SG, Harbour D, Poubelle PE 1996 Role of protein kinase Cα, Arf, and cytoplasmic calcium transient in phospholipase D activation by sodium fluoride in osteoblast-like cells. J Bone Miner Res 11:1655-1665.
    • (1996) J Bone Miner Res , vol.11 , pp. 1655-1665
    • Bourgoin, S.G.1    Harbour, D.2    Poubelle, P.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.