Cardiac injury after 10 gy total body irradiation: Indirect role of effects on abdominal organs

Radiation Research

Volumn 180, Issue 3, 2013, Pages 247-258

  Lenarczyk, Marek ^a   Lam, Vy ^a   Jensen, Eric ^b,c   Fish, Brian L ^a   Su, Jidong ^a   Koprowski, Stacy ^a   Komorowski, Richard A ^c   Harmann, Leanne ^c   Migrino, Raymond Q ^d   Li, X Allen ^a   Hopewell, John W ^e   Moulder, John E ^a   Baker, John E ^a,c,f  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b Departments of Pediatrics   (United States)

^c Department of Radiation Oncology ^*  (United States)

^d CARL T HAYDEN VA MEDICAL CENTER   (United States)

^e UNIVERSITY OF OXFORD   (United Kingdom)

^f Children's Hospital of Wisconsin   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CREATININE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; NITROGEN; TRIACYLGLYCEROL; UREA;

ABDOMEN; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CREATININE BLOOD LEVEL; HEART INJURY; INTESTINE; KIDNEY; KIDNEY INJURY; LIVER; LIVER HISTOLOGY; MALE; NONHUMAN; PRIORITY JOURNAL; RADIATION DOSE; RADIATION PROTECTION; RAT; RISK FACTOR; TRIACYLGLYCEROL BLOOD LEVEL; UREA NITROGEN BLOOD LEVEL; WHOLE BODY RADIATION;

ANIMALS; BASE SEQUENCE; DNA PRIMERS; HEART; INTESTINES; KIDNEY; MALE; RADIATION DOSAGE; RADIATION INJURIES, EXPERIMENTAL; RATS; RISK FACTORS; WHOLE-BODY IRRADIATION;

EID: 84884273934     PISSN: 00337587     EISSN: 19385404     Source Type: Journal    
DOI: 10.1667/RR3292.1     Document Type: Article

References (36)

1. Mulrooney DA, Yeazel MW, Kawashima T, Mertens AC, Mitby P, Stovall M, et al. Cardiac outcomes in a cohort of adult survivors of childhood and adolescent cancer: retrospective analysis of the Childhood Cancer Survivor Study cohort. BMJ 2009;339b4606.
2. Meacham LR, Chow EJ, Ness KK, Kamdar KY, Chen Y, Yasui Y, et al. Cardiovascular risk factors in adult survivors of pediatric cancer-a report from the childhood cancer survivor study. Cancer Epidemiol Biomarkers Prev 2010; 19(1):170-81.
3. Frisk P, Arvidson J, Larsson M, Naessen T. Risk factors for cardiovascular disease are increased in young adults treated with stem cell transplantation during childhood. Pediatr Transplant 2012; 16(4):385-91.
4. Preston DL, Shimizu Y, Pierce DA, Suyama A, Mabuchi K. Studies of mortality of atomic bomb survivors. Report 13: Solid cancer and noncancer disease mortality: 1950-1997. Radiat Res 2003; 160(4):381-407.
5. Yamada M, Wong FL, Fujiwara S, Akahoshi M, Suzuki G. Noncancer disease incidence in atomic bomb survivors, 1958-1998. Radiat Res 2004; 161(6):622-32.
6. Baker JE, Fish BL, Su J, Haworth ST, Strande JL, Komorowski RA, et al. 10 Gy total body irradiation increases risk of coronary sclerosis, degeneration of heart structure and function in a rat model. Int J Radiat Biol 2009; 85(12):1089-100.
7. Coleman CN, Blakely WF, Fike JR, Macvittie TJ, Metting NF, Mitchell JB, et al. Molecular and cellular biology of moderate-dose (1-10 Gy) radiation and potential mechanisms of radiation protection: report of a workshop at Bethesda, Maryland, December 17-18, 2001. Radiat Res 2003; 159(6):812-34.
8. Cohen EP. Radiation nephropathy after bone marrow transplantation. Kidney Int 2000; 58(2):903-18.
9. O'donoghue J. Relevance of external beam dose-response relationships to kidney toxicity associated with radionuclide therapy. Cancer Biother Radiopharm 2004; 19(3):378-87.
10. Adams MJ, Grant EJ, Kodama K, Shimizu Y, Kasagi F, Suyama A, et al. Radiation dose associated with renal failure mortality: a potential pathway to partially explain increased cardiovascular disease mortality observed after whole-body irradiation. Radiat Res 2012; 177(2):220-8.
11. Wang J, Zheng H, Ou X, Albertson CM, Fink LM, Herbert JM, et al. Hirudin ameliorates intestinal radiation toxicity in the rat: support for thrombin inhibition as strategy to minimize side-effects after radiation therapy and as countermeasure against radiation exposure. J Thromb Haemost 2004; 2(11):2027-35.
12. Lawton CA, Barber-Derus SW, Murray KJ, Cohen EP, Ash RC, Moulder JE. Influence of renal shielding on the incidence of late renal dysfunction associated with T-lymphocyte deplete bone marrow transplantation in adult patients. Int J Radiat Oncol Biol Phys 1992; 23(3):681-6.
13. Cohen EP, Fish BL, Sharma M, Li XA, Moulder JE. Role of the angiotensin II type-2 receptor in radiation nephropathy. Transl Res 2007; 150(2):106-15.
14. Moulder JE, Fish BL. Late toxicity of total body irradiation with bone marrow transplantation in a rat model. Int J Radiat Oncol Biol Phys 1989;16(6):1501-9.
15. Moulder JE, Holcenberg JS, Kamen BA, Cheng M, Fish BL. Renal irradiation and the pharmacology and toxicity of methotrexate and cisplatinum. Int J Radiat Oncol Biol Phys 1986; 12(8):1415-8.
16. Croswell A, Amir E, Teggatz P, Barman M, Salzman NH. Prolonged impact of antibiotics on intestinal microbial ecology and susceptibility to enteric Salmonella infection. Infect Immun 2009;77(7):2741-53.
17. Migrino RQ, Zhu X, Pajewski N, Brahmbhatt T, Hoffmann R, Zhao M. Assessment of segmental myocardial viability using regional 2-dimensional strain echocardiography. J Am Soc Echocardiogr 2007; 20(4):342-51.
18. Cabral HJ. Multiple comparisons procedures. Circulation 2008; 117(5):698-701.
19. Andrews HL, Brace KC. Modification of early radiation death in guinea pigs. Am. J. Physiol. 1956; 187(2):378-80.
20. Mack HP, Figge FH. Sodium pentobarbital anesthesia and mortality from X-radiation in C57 black mice. Science 1952; 115(2994):547-8.
21. Lam V, Moulder JE, Salzman NH, Dubinsky EA, Andersen GL, Baker JE. Intestinal microbiota as novel biomarkers of prior radiation exposure. Radiat Res 2012; 177(5):573-83.
22. Chen MH, Colan SD, Diller L. Cardiovascular disease: cause of morbidity and mortality in adult survivors of childhood cancers. Circ Res 2011; 108(5):619-28.
23. Sera N, Hida A, Imaizumi M, Nakashima E, Akahoshi M. The association between chronic kidney disease and cardiovascular disease risk factors in atomic bomb survivors. Radiat Res 2013; 179(1):46-52.
24. Boerma M, Roberto KA, Hauer-Jensen M. Prevention and treatment of functional and structural radiation injury in the rat heart by pentoxifylline and alpha-tocopherol. Int J Radiat Oncol Biol Phys 2008; 72(1):170-7.
25. Boerma M, Wang J, Wondergem J, Joseph J, Qiu X, Kennedy RH, et al. Influence of mast cells on structural and functional manifestations of radiation-induced heart disease. Cancer Res 2005; 65(8):3100-7.
26. Fajardo LF, Stewart JR. Cardiovascular radiation syndrome. N Engl J Med 1970; 283(7):374.
27. Yeung TK, Hopewell JW. Effects of single doses of radiation on cardiac function in the rat. Radiother Oncol 1985;3(4):339-45.
28. Darby SC, Cutter DJ, Boerma M, Constine LS, Fajardo LF, Kodama K, et al. Radiation-related heart disease: current knowledge and future prospects. Int J Radiat Oncol Biol Phys 2010; 76(3):656-65.
29. Migrino RQ, Aggarwal D, Konorev E, Brahmbhatt T, Bright M, Kalyanaraman B. Early detection of doxorubicin cardiomyopathy using two-dimensional strain echocardiography. Ultrasound Med Biol 2008; 34(2):208-14.
30. Pieper GM, Shah A, Harmann L, Cooley BC, Ionova IA, Migrino RQ. Speckle-tracking 2-dimensional strain echocardiography: a new noninvasive imaging tool to evaluate acute rejection in cardiac transplantation. J Heart Lung Transplant 2010; 29(9):1039-46.
31. Migrino RQ, Zhu X, Morker M, Brahmbhatt T, Bright M, Zhao M. Myocardial dysfunction in the periinfarct and remote regions following anterior infarction in rats quantified by 2D radial strain echocardiography: an observational cohort study. Cardiovasc Ultrasound 2008; 6:17.
32. Migrino RQ, Ahn KW, Brahmbhatt T, Harmann L, Jurva J, Pajewski NM. Usefulness of two-dimensional strain echocardiography to predict segmental viability following acute myocardial infarction and optimization using bayesian logistic spatial modeling. Am J Cardiol 2009; 104(8):1023-9.
33. Neben-Wittich MA, Wittich CM, Mueller PS, Larson DR, Gertz MA and Edwards WD. Obstructive intramural coronary amyloid-osis and myocardial ischemia are common in primary amyloidosis. Am J Med 2005; 118(11):1287.
34. Moulder JE, Fish BL, Cohen EP. Impact of angiotensin II type 2 receptor blockade on experimental radiation nephropathy. Radiat Res 2004; 161(3):312-7.
35. Geraci JP, Mariano MS. Radiation hepatology of the rat: parenchymal and nonparenchymal cell injury. Radiat Res 1993; 136(2):205-13.
36. Huff J and Cucinotta FA, Risk of degenerative tissue or other health effects from radiation exposure. In: Mcphee J, Charles J, editors., Human Health and performance risks of space exploration missions National Aeronautics and Space Administration, NASA SP-2009-3405, Houston, TX, 2009. pp. 213-35.