Risk factors for cardiovascular disease are increased in young adults treated with stem cell transplantation during childhood

Pediatric Transplantation

Volumn 16, Issue 4, 2012, Pages 385-391

  Frisk, Per ^a,b   Arvidson, Johan ^a   Larsson, Marita ^a   Naessén, Tord ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b UNIVERSITY CHILDREN S HOSPITAL   (Sweden)

Author keywords

adiponectin; cardiovascular disease; intima and media thickness; metabolic syndrome; stem cell transplantation

Indexed keywords

ADIPONECTIN; APOLIPOPROTEIN A1; APOLIPOPROTEIN B; CHOLESTEROL; CYCLOPHOSPHAMIDE; CYCLOSPORIN; GROWTH HORMONE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; METHOTREXATE; TRIACYLGLYCEROL;

ADOLESCENT; ADULT; AGE DISTRIBUTION; ARTERIAL WALL THICKNESS; ARTICLE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CHILD; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GRAFT VERSUS HOST REACTION; HUMAN; MALE; METABOLIC SYNDROME X; SCHOOL CHILD; SEX RATIO; STEM CELL TRANSPLANTATION; SURVIVAL RATE; SURVIVOR; TRIACYLGLYCEROL BLOOD LEVEL;

ADIPONECTIN; ADOLESCENT; ADULT; ARTERIOSCLEROSIS; BIOLOGICAL MARKERS; BLOOD PRESSURE; BODY MASS INDEX; CARDIOVASCULAR DISEASES; CAROTID INTIMA-MEDIA THICKNESS; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; CROSS-SECTIONAL STUDIES; FEMALE; FOLLOW-UP STUDIES; HUMANS; INFANT; LIPIDS; MALE; METABOLIC SYNDROME X; POSTOPERATIVE COMPLICATIONS; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; RISK FACTORS; STEM CELL TRANSPLANTATION; YOUNG ADULT;

EID: 84861200372     PISSN: 13973142     EISSN: 13993046     Source Type: Journal    
DOI: 10.1111/j.1399-3046.2012.01693.x     Document Type: Article

References (41)

1. Link K, Moell C, Garwicz S, et al., Growth hormone deficiency predicts cardiovascular risk in young adults treated for acute lymphoblastic leukemia in childhood. J Clin Endocrinol Metab 2004: 89: 5003-5012. (Pubitemid 39391441)
2. Jarfelt M, Lannering B, Bosaeus I, Johannsson G, Bjarnason R,. Body composition in young adult survivors of childhood acute lymphoblastic leukaemia. Eur J Endocrinol 2005: 153: 81-89. (Pubitemid 41030519)
3. Gurney JG, Ness KK, Sibley SD, et al., Metabolic syndrome and growth hormone deficiency in adult survivors of childhood acute lymphoblastic leukemia. Cancer 2006: 107: 1303-1312. (Pubitemid 44452780)
4. Oeffinger KC, Adams-Huet B, Victor RG, et al., Insulin resistance and risk factors for cardiovascular disease in young adult survivors of childhood acute lymphoblastic leukemia. J Clin Oncol 2009: 27: 3698-3704.
5. Chow EJ, Simmons JH, Roth CL, et al., Increased cardiometabolic traits in pediatric survivors of acute lymphoblastic leukemia treated with total body irradiation. Biol Blood Marrow Transplant 2010: 16: 1674-1681.
6. Eckel RH, Grundy SM, Zimmet PZ,. The metabolic syndrome. Lancet 2005: 365: 1415-1428. (Pubitemid 40523737)
7. Taskinen M, Saarinen-Pihkala UM, Hovi L, Lipsanen-Nyman M,. Impaired glucose tolerance and dyslipidaemia as late effects after bone-marrow transplantation in childhood. Lancet 2000: 356: 993-997.
8. Neville KA, Cohn RJ, Steinbeck KS, Johnston K, Walker JL,. Hyperinsulinemia, impaired glucose tolerance, and diabetes mellitus in survivors of childhood cancer: Prevalence and risk factors. J Clin Endocrinol Metab 2006: 91: 4401-4407. (Pubitemid 44833416)
9. Baker KS, Ness KK, Steinberger J, et al., Diabetes, hypertension, and cardiovascular events in survivors of hematopoietic cell transplantation: A report from the bone marrow transplantation survivor study. Blood 2007: 109: 1765-1772. (Pubitemid 46239613)
10. Steffens M, Beauloye V, Brichard B, et al., Endocrine and metabolic disorders in young adult survivors of childhood acute lymphoblastic leukaemia (ALL) or non-Hodgkin lymphoma (NHL). Clin Endocrinol (Oxf) 2008: 69: 819-827.
11. Meacham LR, Chow EJ, Ness KK, et al., Cardiovascular risk factors in adult survivors of pediatric cancer - a report from the childhood cancer survivor study. Cancer Epidemiol Biomarkers Prev 2010: 19: 170-181.
12. Oudin C, Simeoni MC, Sirvent N, et al., Prevalence and risk factors of the metabolic syndrome in adult survivors of childhood leukemia. Blood 2011: 117: 4442-4448.
13. Brennan BM, Shalet SM,. Endocrine late effects after bone marrow transplant. Br J Haematol 2002: 118: 58-66. (Pubitemid 34779517)
14. Shalitin S, Phillip M, Stein J, Goshen Y, Carmi D, Yaniv I,. Endocrine dysfunction and parameters of the metabolic syndrome after bone marrow transplantation during childhood and adolescence. Bone Marrow Transplant 2006: 37: 1109-1117. (Pubitemid 43871521)
15. Taskinen M, Lipsanen-Nyman M, Tiitinen A, Hovi L, Saarinen-Pihkala UM,. Insufficient growth hormone secretion is associated with metabolic syndrome after allogeneic stem cell transplantation in childhood. J Pediatr Hematol Oncol 2007: 29: 529-534. (Pubitemid 47356806)
16. Siviero-Miachon AA, Spinola-Castro AM, Guerra-Junior G,. Detection of metabolic syndrome features among childhood cancer survivors: A target to prevent disease. Vasc Health Risk Manag 2008: 4: 825-836.
17. Hansson GK,. Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med 2005: 352: 1685-1695.
18. Greenland P, Abrams J, Aurigemma GP, et al., Prevention Conference V: Beyond secondary prevention: Identifying the high-risk patient for primary prevention: Noninvasive tests of atherosclerotic burden: Writing Group III. Circulation 2000: 101: E16-E22.
19. Gustafsson G, Kreuger A, Clausen N, et al., Intensified treatment of acute childhood lymphoblastic leukaemia has improved prognosis, especially in non-high-risk patients: The Nordic experience of 2648 patients diagnosed between 1981 and 1996. Nordic Society of Paediatric Haematology and Oncology (NOPHO). Acta Paediatr 1998: 87: 1151-1161. (Pubitemid 28538425)
20. Lonnerholm G, Simonsson B, Arvidson J, et al., Autologous bone marrow transplantation in children with acute lymphoblastic leukemia. Acta Paediatr 1992: 81: 1017-1022. (Pubitemid 23044779)
21. Jarfelt M, Bjarnason R, Lannering B,. Young adult survivors of childhood acute lymphoblastic leukemia: Spontaneous GH secretion in relation to CNS radiation. Pediatr Blood Cancer 2004: 42: 582-588. (Pubitemid 38669745)
22. Frisk P, Rossner SM, Norgren S, Arvidson J, Gustafsson J,. Glucose metabolism and body composition in young adults treated with TBI during childhood. Bone Marrow Transplant 2011: 46: 1303-1308.
23. Alberti KG, Eckel RH, Grundy SM, et al., Harmonizing the metabolic syndrome: A joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation 2009: 120: 1640-1645.
24. Rodriguez-Macias KA, Lind L, Naessen T,. Thicker carotid intima layer and thinner media layer in subjects with cardiovascular diseases. An investigation using noninvasive high-frequency ultrasound. Atherosclerosis 2006: 189: 393-400. (Pubitemid 44634501)
25. Naessen T, Rodriguez-Macias K,. Menopausal estrogen therapy counteracts normal aging effects on intima thickness, media thickness and intima/media ratio in carotid and femoral arteries. An investigation using noninvasive high-frequency ultrasound. Atherosclerosis 2006: 189: 387-392. (Pubitemid 44634483)
26. Bohman H, Jonsson U, Von Knorring AL, et al., Thicker carotid intima layer, thinner media layer and higher intima/media ratio in women with recurrent depressive disorders: A pilot study using non-invasive high frequency ultrasound. World J Biol Psychiatry 2010: 11: 71-75.
27. Weber G, Bianciardi G, Bussani R, et al., Atherosclerosis and aging. A morphometric study on arterial lesions of elderly and very elderly necropsy subjects. Arch Pathol Lab Med 1988: 112: 1066-1070.
28. Gussenhoven EJ, Frietman PA, The SH, et al., Assessment of medial thinning in atherosclerosis by intravascular ultrasound. Am J Cardiol 1991: 68: 1625-1632.
29. Leonard D, Akhter T, Nordmark G, Ronnblom L, Naessen T,. Increased carotid intima thickness and decreased media thickness in premenopausal women with systemic lupus erythematosus: An investigation by non-invasive high-frequency ultrasound. Scand J Rheumatol 2011: 40: 279-282.
30. Armenian SH, Sun CL, Kawashima T, et al., Long-term health-related outcomes in survivors of childhood cancer treated with HSCT versus conventional therapy: A report from the Bone Marrow Transplant Survivor Study (BMTSS) and Childhood Cancer Survivor Study (CCSS). Blood 2011: 118: 1413-1420.
31. Nysom K, Holm K, Michaelsen KF, et al., Degree of fatness after allogeneic BMT for childhood leukaemia or lymphoma. Bone Marrow Transplant 2001: 27: 817-820. (Pubitemid 32496414)
32. Lind L,. Apolipoprotein B/A1 and risk of cardiovascular disease. Lancet 2008: 372: 185-186. (Pubitemid 351978091)
33. Packard RR, Libby P,. Inflammation in atherosclerosis: From vascular biology to biomarker discovery and risk prediction. Clin Chem 2008: 54: 24-38. (Pubitemid 351182593)
34. Bengtsson BA, Abs R, Bennmarker H, et al., The effects of treatment and the individual responsiveness to growth hormone (GH) replacement therapy in 665 GH-deficient adults. KIMS Study Group and the KIMS International Board. J Clin Endocrinol Metab 1999: 84: 3929-3935. (Pubitemid 30644176)
35. Griffith ML, Savani BN, Boord JB,. Dyslipidemia after allogeneic hematopoietic stem cell transplantation: Evaluation and management. Blood 2010: 116: 1197-1204.
36. Roman MJ, Shanker BA, Davis A, et al., Prevalence and correlates of accelerated atherosclerosis in systemic lupus erythematosus. N Engl J Med 2003: 349: 2399-2406. (Pubitemid 37542988)
37. Lara-Castro C, Fu Y, Chung BH, Garvey WT,. Adiponectin and the metabolic syndrome: Mechanisms mediating risk for metabolic and cardiovascular disease. Curr Opin Lipidol 2007: 18: 263-270. (Pubitemid 46743049)
38. Hopkins TA, Ouchi N, Shibata R, Walsh K,. Adiponectin actions in the cardiovascular system. Cardiovasc Res 2007: 74: 11-18. (Pubitemid 46366942)
39. Saarikoski LA, Huupponen RK, Viikari JS, et al., Adiponectin is related with carotid artery intima-media thickness and brachial flow-mediated dilatation in young adults-the Cardiovascular Risk in Young Finns Study. Ann Med 2010: 42: 603-611.
40. Gianicolo ME, Gianicolo EA, Tramacere F, Andreassi MG, Portaluri M,. Effects of external irradiation of the neck region on intima media thickness of the common carotid artery. Cardiovasc Ultrasound 2010: 8: 8.
41. Russell NS, Hoving S, Heeneman S, et al., Novel insights into pathological changes in muscular arteries of radiotherapy patients. Radiother Oncol 2009: 92: 477-483.