Comprehensive two-dimensional liquid chromatography separations of pharmaceutical samples using dual Fused-Core columns in the 2nd dimension

Journal of Chromatography A

Volumn 1216, Issue 9, 2009, Pages 1338-1345

  Alexander, Anthony J ^a   Ma, Lianjia ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

Comprehensive two dimensional; Dual parallel 2nd dimension columns; Fused Core; Pharmaceutical degradation products

Indexed keywords

ACTIVE PHARMACEUTICAL INGREDIENTS; AMBIENT TEMPERATURES; BACK PRESSURES; COMPREHENSIVE TWO-DIMENSIONAL; COMPREHENSIVE TWO-DIMENSIONAL LIQUID CHROMATOGRAPHIES; CONFIGURABLE; CONVENTIONAL METHODS; CORE COLUMNS; CYCLE TIME; DUAL PARALLEL 2ND DIMENSION COLUMNS; FUSED-CORE; MINOR COMPONENTS; MOBILE-PHASE COMPOSITIONS; OXIDATION PRODUCTS; PHARMACEUTICAL ANALYSIS; PHARMACEUTICAL DEGRADATION PRODUCTS; PUMPING SYSTEMS; SAMPLING RATES; SPECIFIC PROBLEMS; THREE COMPONENTS;

CHROMATOGRAPHIC ANALYSIS; DEGRADATION; HIGH PRESSURE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MIXTURES; PHASE INTERFACES; TWO DIMENSIONAL;

DRUG PRODUCTS;

BUSPIRONE;

ARTICLE; DEGRADATION; ENVIRONMENTAL TEMPERATURE; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; OXIDATION; PH; PHOTODEGRADATION; PRESSURE; PRIORITY JOURNAL; REVERSED PHASE LIQUID CHROMATOGRAPHY;

CHROMATOGRAPHY, LIQUID; DRUG CONTAMINATION; EQUIPMENT DESIGN; HYDROGEN-ION CONCENTRATION; PHARMACEUTICAL PREPARATIONS; PRESSURE; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TIME FACTORS;

EID: 59049091686     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2008.12.063     Document Type: Article

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