The chemokine CXCL12 generates costimulatory signals in T cells to enhance phosphorylation and clustering of the adaptor protein SLP-76

Science Signaling

Volumn 6, Issue 286, 2013, Pages

  Smith, Xin ^a   Schneider, Helga ^a,b   Köhler, Karsten ^a   Liu, Hebin ^b   Lu, Yuning ^a,b   Rudd, Christopher E ^a,b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; CD3 ANTIGEN; CHEMOKINE RECEPTOR CXCR4; F ACTIN; GUANINE NUCLEOTIDE BINDING PROTEIN; PROTEIN KINASE ZAP 70; PROTEIN SLP 76; STROMAL CELL DERIVED FACTOR 1; T LYMPHOCYTE RECEPTOR; TYROSINE; UNCLASSIFIED DRUG; ACTIN; CXCL12 PROTEIN, HUMAN; CXCR4 PROTEIN, HUMAN; PHOSPHOPROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SLP 76 SIGNAL TRANSDUCING ADAPTOR PROTEINS; SLP-76 SIGNAL TRANSDUCING ADAPTOR PROTEINS;

ACTIN POLYMERIZATION; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; GENE MUTATION; IMMUNE RESPONSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; ANIMAL; CELL PROLIFERATION; CHEMISTRY; CLUSTER ANALYSIS; CYTOLOGY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUORESCENCE MICROSCOPY; HUMAN; LEUKEMIA CELL LINE; METABOLISM; MOUSE; MUTATION; PHOSPHORYLATION; SPLEEN; T LYMPHOCYTE; JURKAT CELL LINE;

ACTINS; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTIGENS, CD3; CELL PROLIFERATION; CHEMOKINE CXCL12; CLUSTER ANALYSIS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HUMANS; JURKAT CELLS; MICE; MICROSCOPY, FLUORESCENCE; MUTATION; PHOSPHOPROTEINS; PHOSPHORYLATION; RECEPTORS, CXCR4; SIGNAL TRANSDUCTION; SPLEEN; T-LYMPHOCYTES; TYROSINE; ZAP-70 PROTEIN-TYROSINE KINASE;

EID: 84884249236     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2004018     Document Type: Article

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