-
1
-
-
36248965689
-
Current challenges in non-invasive insulin delivery systems: A comparative review
-
Khafagy S, Morishita M, Onuki Y, Takayama K. Current challenges in non-invasive insulin delivery systems: a comparative review. Adv Drug Deliv Rev. 2007;59(15):1521-1546.
-
(2007)
Adv Drug Deliv Rev
, vol.59
, Issue.15
, pp. 1521-1546
-
-
Khafagy, S.1
Morishita, M.2
Onuki, Y.3
Takayama, K.4
-
2
-
-
83355173904
-
Goblet cell-targeting nanoparticles for oral insulin delivery and the influence of mucus on insulin transport
-
Jin Y, Song YP, Zhu X, et al. Goblet cell-targeting nanoparticles for oral insulin delivery and the influence of mucus on insulin transport. Biomaterials. 2012;33(5):1573-1582.
-
(2012)
Biomaterials
, vol.33
, Issue.5
, pp. 1573-1582
-
-
Jin, Y.1
Song, Y.P.2
Zhu, X.3
-
3
-
-
17144371646
-
Effects of exenatide (exendin-4) on glycemic control over 30 weeks in patients with type 2 diabetes treated with metformin and a sulfonylurea
-
Kendall DM, Riddle MC, Rosenstock J, et al. Effects of exenatide (exendin-4) on glycemic control over 30 weeks in patients with type 2 diabetes treated with metformin and a sulfonylurea. Diabetes Care. 2005;28(9):1083-1091.
-
(2005)
Diabetes Care
, vol.28
, Issue.9
, pp. 1083-1091
-
-
Kendall, D.M.1
Riddle, M.C.2
Rosenstock, J.3
-
4
-
-
0036092239
-
Banting lecture 2001: Dysregulation of fatty acid metabolism in the etiology of type 2 diabetes
-
McGarry JD. Banting lecture 2001: dysregulation of fatty acid metabolism in the etiology of type 2 diabetes. Diabetes. 2002;51(1):7-18.
-
(2002)
Diabetes
, vol.51
, Issue.1
, pp. 7-18
-
-
McGarry, J.D.1
-
5
-
-
0034998738
-
Etiology of type II diabetes mellitus: Role of the foregut
-
Pories WJ, Albrecht RJ. Etiology of type II diabetes mellitus: role of the foregut. World J Surg. 2001;25(4):527-531.
-
(2001)
World J Surg
, vol.25
, Issue.4
, pp. 527-531
-
-
Pories, W.J.1
Albrecht, R.J.2
-
6
-
-
34247232203
-
Exenatide: A review of its use in patients with type 2 diabetes mellitus (as an adjunct to metformin and/or a sulfonylurea)
-
Cvetković RS, Plosker GL. Exenatide: a review of its use in patients with type 2 diabetes mellitus (as an adjunct to metformin and/or a sulfonylurea). Drugs. 2007;67(6):935-954.
-
(2007)
Drugs
, vol.67
, Issue.6
, pp. 935-954
-
-
Cvetković, R.S.1
Plosker, G.L.2
-
7
-
-
33645533439
-
Exenatide: From the Gila monster to the pharmacy
-
Triplitt C, Chiquette E. Exenatide: from the Gila monster to the pharmacy. J Am Pharm Assoc (2003). 2006;46(1):44-55.
-
(2006)
J Am Pharm Assoc (2003)
, vol.46
, Issue.1
, pp. 44-55
-
-
Triplitt, C.1
Chiquette, E.2
-
8
-
-
65549112678
-
Exenatide: A review from pharmacology to clinical practice
-
Gentilella R, Bianchi C, Rossi A, Rotella CM. Exenatide: a review from pharmacology to clinical practice. Diabetes Obes Metab. 2009;11(6): 544-556.
-
(2009)
Diabetes Obes Metab
, vol.11
, Issue.6
, pp. 544-556
-
-
Gentilella, R.1
Bianchi, C.2
Rossi, A.3
Rotella, C.M.4
-
9
-
-
0026648961
-
Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom. Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas
-
Eng J, Kleinman WA, Singh L, Singh G, Raufman JP. Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom. Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas. J Biol Chem. 1992;267(11):7402-7405.
-
(1992)
J Biol Chem
, vol.267
, Issue.11
, pp. 7402-7405
-
-
Eng, J.1
Kleinman, W.A.2
Singh, L.3
Singh, G.4
Raufman, J.P.5
-
10
-
-
42949112670
-
Exenatide and rare adverse events
-
Cure P, Pileggi A, Alejandro R. Exenatide and rare adverse events. N Engl J Med. 2008;358(18):1969-1972.
-
(2008)
N Engl J Med
, vol.358
, Issue.18
, pp. 1969-1972
-
-
Cure, P.1
Pileggi, A.2
Alejandro, R.3
-
11
-
-
0347360186
-
Pharmacology of exenatide (synthetic exendin-4): A potential therapeutic for improved glycemic control of type 2 diabetes
-
Nielsen LL, Young AA, Parkes DG. Pharmacology of exenatide (synthetic exendin-4): a potential therapeutic for improved glycemic control of type 2 diabetes. Regul Pept. 2004;117(2):77-88.
-
(2004)
Regul Pept
, vol.117
, Issue.2
, pp. 77-88
-
-
Nielsen, L.L.1
Young, A.A.2
Parkes, D.G.3
-
12
-
-
0038497464
-
Synthetic exendin-4 (exenatide) significantly reduces postprandial and fasting plasma glucose in subjects with type 2 diabetes
-
Kolterman OG, Buse JB, Fineman MS, et al. Synthetic exendin-4 (exenatide) significantly reduces postprandial and fasting plasma glucose in subjects with type 2 diabetes. J Clin Endocrinol Metab. 2003;88(7):3082-3089.
-
(2003)
J Clin Endocrinol Metab
, vol.88
, Issue.7
, pp. 3082-3089
-
-
Kolterman, O.G.1
Buse, J.B.2
Fineman, M.S.3
-
13
-
-
84875872427
-
An evidence-based and practical approach to using Bydureon™ in patients with type 2 diabetes
-
Painter NA, Morello CM, Singh RF, McBane SE. An evidence-based and practical approach to using Bydureon™ in patients with type 2 diabetes. J Am Board Fam Med. 2013;26(2):203-210.
-
(2013)
J Am Board Fam Med
, vol.26
, Issue.2
, pp. 203-210
-
-
Painter, N.A.1
Morello, C.M.2
Singh, R.F.3
McBane, S.E.4
-
14
-
-
78751487490
-
Release pattern improvement of nomegestrol from biodegradable microspheres by using polymer-alloys as matrix
-
Xiao L, Chen Q, Bao Y, Pan F. Release pattern improvement of nomegestrol from biodegradable microspheres by using polymer-alloys as matrix. Asian J Pharm Sci. 2010;5(6):231-238.
-
(2010)
Asian J Pharm Sci
, vol.5
, Issue.6
, pp. 231-238
-
-
Xiao, L.1
Chen, Q.2
Bao, Y.3
Pan, F.4
-
15
-
-
0031059837
-
Effect of processing parameters on the properties of peptide-containing PLGA microspheres
-
Jeyanthi R, Mehta RC, Thanoo BC, DeLuca PP. Effect of processing parameters on the properties of peptide-containing PLGA microspheres. J Microencapsul. 1997;14(2):163-174.
-
(1997)
J Microencapsul
, vol.14
, Issue.2
, pp. 163-174
-
-
Jeyanthi, R.1
Mehta, R.C.2
Thanoo, B.C.3
Deluca, P.P.4
-
16
-
-
24344445499
-
A HER-2/neu peptide admixed with PLA microspheres induces a Th1-biased immune response in mice
-
Nikou KN, Stivaktakis N, Avgoustakis K, et al. A HER-2/neu peptide admixed with PLA microspheres induces a Th1-biased immune response in mice. Biochim Biophys Acta. 2005;1725(2):182-189.
-
(2005)
Biochim Biophys Acta
, vol.1725
, Issue.2
, pp. 182-189
-
-
Nikou, K.N.1
Stivaktakis, N.2
Avgoustakis, K.3
-
17
-
-
84882740524
-
-
inventors; Alkermes Inc, assignee, United States patent US7456254 B2. November 1
-
Wright SG, Christenson T, Yeah TY, et al, inventors; Alkermes Inc, assignee. Polymer-based sustained release device. United States patent US7456254 B2. November 1, 2008.
-
(2008)
Polymer-based sustained release device
, pp. 1
-
-
Wright, S.G.1
Christenson, T.2
Yeah, T.Y.3
-
18
-
-
84865359777
-
Application of model-based methods to characterize exenatide-loaded double-walled microspheres: In vivo release, pharmacokinetic/pharmacodynamic model, and in vitro and in vivo correlation
-
Li X, Li L, Wang X, Ren Y, Zhou T, Lu W. Application of model-based methods to characterize exenatide-loaded double-walled microspheres: in vivo release, pharmacokinetic/pharmacodynamic model, and in vitro and in vivo correlation. J Pharm Sci. 2012;101(10):3946-3961.
-
(2012)
J Pharm Sci
, vol.101
, Issue.10
, pp. 3946-3961
-
-
Li, X.1
Li, L.2
Wang, X.3
Ren, Y.4
Zhou, T.5
Lu, W.6
-
19
-
-
80052731231
-
Encapsulation of exenatide in poly-(D,L-lactide-co-glycolide) microspheres produced an investigational long-acting once-weekly formulation for type 2 diabetes
-
DeYoung MB, MacConell L, Sarin V, Trautmann M, Herbert P. Encapsulation of exenatide in poly-(D,L-lactide-co-glycolide) microspheres produced an investigational long-acting once-weekly formulation for type 2 diabetes. Diabetes Technol Ther. 2011;13(11): 1145-1154.
-
(2011)
Diabetes Technol Ther
, vol.13
, Issue.11
, pp. 1145-1154
-
-
Deyoung, M.B.1
Macconell, L.2
Sarin, V.3
Trautmann, M.4
Herbert, P.5
-
20
-
-
53249142132
-
Exenatide once weekly versus twice daily for the treatment of type 2 diabetes: A randomised, open-label, non-inferiority study
-
Drucker DJ, Buse JB, Taylor K, et al. Exenatide once weekly versus twice daily for the treatment of type 2 diabetes: a randomised, open-label, non-inferiority study. Lancet. 2008;372(9645):1240-1250.
-
(2008)
Lancet
, vol.372
, Issue.9645
, pp. 1240-1250
-
-
Drucker, D.J.1
Buse, J.B.2
Taylor, K.3
-
21
-
-
84867344249
-
Safety of exenatide once weekly in patients with type 2 diabetes mellitus treated with a thiazolidinedione alone or in combination with metformin for 2 years
-
Norwood P, Liutkus JF, Haber H, et al. Safety of exenatide once weekly in patients with type 2 diabetes mellitus treated with a thiazolidinedione alone or in combination with metformin for 2 years. Clin Ther. 2012;34(10):2082-2090.
-
(2012)
Clin Ther
, vol.34
, Issue.10
, pp. 2082-2090
-
-
Norwood, P.1
Liutkus, J.F.2
Haber, H.3
-
22
-
-
84883743991
-
Once weekly exenatide: Efficacy, tolerability and place in therapy
-
Epub February 20
-
Wysham C, Grimm M, Chen S. Once weekly exenatide: efficacy, tolerability and place in therapy. Diabetes Obes Metab. Epub February 20, 2013.
-
(2013)
Diabetes Obes Metab
-
-
Wysham, C.1
Grimm, M.2
Chen, S.3
-
23
-
-
67449086488
-
Exenatide once weekly for the treatment of type 2 diabetes
-
Malone J, Trautmann M, Wilhelm K, et al. Exenatide once weekly for the treatment of type 2 diabetes. Expert Opin Investig Drugs. 2009;18(3):359-367.
-
(2009)
Expert Opin Investig Drugs
, vol.18
, Issue.3
, pp. 359-367
-
-
Malone, J.1
Trautmann, M.2
Wilhelm, K.3
-
24
-
-
84862253577
-
Review of the safety and efficacy of exenatide once weekly for the treatment of type 2 diabetes mellitus
-
Murphy CE. Review of the safety and efficacy of exenatide once weekly for the treatment of type 2 diabetes mellitus. Ann Pharmacother. 2012;46(6):812-821.
-
(2012)
Ann Pharmacother
, vol.46
, Issue.6
, pp. 812-821
-
-
Murphy, C.E.1
-
25
-
-
84873274374
-
Comparison of safety and tolerability with continuous (exenatide once weekly) or intermittent (exenatide twice daily) GLP-1 receptor agonism in patients with type 2 diabetes
-
Ridge T, Moretto T, Macconell L, et al. Comparison of safety and tolerability with continuous (exenatide once weekly) or intermittent (exenatide twice daily) GLP-1 receptor agonism in patients with type 2 diabetes. Diabetes Obes Metab. 2012;14(12):1097-1103.
-
(2012)
Diabetes Obes Metab
, vol.14
, Issue.12
, pp. 1097-1103
-
-
Ridge, T.1
Moretto, T.2
Macconell, L.3
-
26
-
-
0037151323
-
Characterization of the initial burst release of a model peptide from poly (D, L-lactide-co-glycolide) microspheres
-
Wang J, Wang BM, Schwendeman SP. Characterization of the initial burst release of a model peptide from poly (D, L-lactide-co-glycolide) microspheres. J Control Release, 2002;82(2):289-307.
-
(2002)
J Control Release
, vol.82
, Issue.2
, pp. 289-307
-
-
Wang, J.1
Wang, B.M.2
Schwendeman, S.P.3
-
27
-
-
0031933272
-
Solvent evaporation processes for the production of controlled release biodegradable microsphere formulations for therapeutics and vaccines
-
Cleland JL. Solvent evaporation processes for the production of controlled release biodegradable microsphere formulations for therapeutics and vaccines. Biotechnol Progr. 1998;14(1):102-107.
-
(1998)
Biotechnol Progr
, vol.14
, Issue.1
, pp. 102-107
-
-
Cleland, J.L.1
-
28
-
-
79955610087
-
Effect of molecular weight of poly(Lactic-co-Glycolide) on properties of exenatide-loaded microspheres
-
Shi L, Liu B, Wang M, et al. Effect of molecular weight of poly(Lactic-co-Glycolide) on properties of exenatide-loaded microspheres. China Modern Medicine. 2009;7:117-118.
-
(2009)
China Modern Medicine
, vol.7
, pp. 117-118
-
-
Shi, L.1
Liu, B.2
Wang, M.3
-
29
-
-
70350244684
-
Pharmacokinetics and efficacy of a biweekly dosage formulation of exenatide in Zucker diabetic fatty (ZDF) rats
-
Kwak HH, Shim WS, Hwang S, et al. Pharmacokinetics and efficacy of a biweekly dosage formulation of exenatide in Zucker diabetic fatty (ZDF) rats. Pharm Res. 2009;26(11):2504-2512.
-
(2009)
Pharm Res
, vol.26
, Issue.11
, pp. 2504-2512
-
-
Kwak, H.H.1
Shim, W.S.2
Hwang, S.3
-
30
-
-
78049461216
-
Preparation, characterization, and pharmacodynamics of exenatide-loaded poly(DL-lactic-co-glycolic acid) microspheres
-
Liu B, Dong Q, Wang M, et al. Preparation, characterization, and pharmacodynamics of exenatide-loaded poly(DL-lactic-co-glycolic acid) microspheres. Chem Pharm Bull (Tokyo). 2010;58(11):1474-1479.
-
(2010)
Chem Pharm Bull (Tokyo)
, vol.58
, Issue.11
, pp. 1474-1479
-
-
Liu, B.1
Dong, Q.2
Wang, M.3
-
31
-
-
78650264619
-
Highly porous large poly(lactic-co-glycolic acid) microspheres adsorbed with palmityl-acylated exendin-4 as a long-acting inhalation system for treating diabetes
-
Kim H, Park H, Lee J, et al. Highly porous large poly(lactic-co-glycolic acid) microspheres adsorbed with palmityl-acylated exendin-4 as a long-acting inhalation system for treating diabetes. Biomaterials. 2011;32(6):1685-1693.
-
(2011)
Biomaterials
, vol.32
, Issue.6
, pp. 1685-1693
-
-
Kim, H.1
Park, H.2
Lee, J.3
-
32
-
-
64849087911
-
Biocompatible microspheres based on acetylated polysaccharide prepared from water-in-oil-in-water (W1/O/W2) double-emulsion method for delivery of type II diabetic drug (exenatide)
-
Yang HJ, Park IS, Na K. Biocompatible microspheres based on acetylated polysaccharide prepared from water-in-oil-in-water (W1/O/W2) double-emulsion method for delivery of type II diabetic drug (exenatide). Colloids Surf A. 2009;340(1/3):115-120.
-
(2009)
Colloids Surf A
, vol.340
, Issue.1-3
, pp. 115-120
-
-
Yang, H.J.1
Park, I.S.2
Na, K.3
-
33
-
-
34547912849
-
Rapidly in situ forming biodegradable robust hydrogels by combining stereocomplexation and photopolymerization
-
Hiemstra C, Zhou W, Zhong Z, Wouters M, Feijen J. Rapidly in situ forming biodegradable robust hydrogels by combining stereocomplexation and photopolymerization. J Am Chem Soc. 2007;129(32):9918-9926.
-
(2007)
J Am Chem Soc
, vol.129
, Issue.32
, pp. 9918-9926
-
-
Hiemstra, C.1
Zhou, W.2
Zhong, Z.3
Wouters, M.4
Feijen, J.5
-
34
-
-
84861076436
-
Hydrogels for protein delivery
-
Vermonden T, Censi R, Hennink WE. Hydrogels for protein delivery. Chem Rev. 2012;112(5):2853-2888.
-
(2012)
Chem Rev
, vol.112
, Issue.5
, pp. 2853-2888
-
-
Vermonden, T.1
Censi, R.2
Hennink, W.E.3
-
36
-
-
84873096405
-
A long-acting formulation of a polypeptide drug exenatide in treatment of diabetes using an injectable block copolymer hydrogel
-
Li K, Yu L, Liu X, Chen C, Chen Q, Ding J. A long-acting formulation of a polypeptide drug exenatide in treatment of diabetes using an injectable block copolymer hydrogel. Biomaterials. 2013;34(11):2834-2842.
-
(2013)
Biomaterials
, vol.34
, Issue.11
, pp. 2834-2842
-
-
Li, K.1
Yu, L.2
Liu, X.3
Chen, C.4
Chen, Q.5
Ding, J.6
-
37
-
-
84884265420
-
GLP-1 analogue formulations
-
inventors, applicants, European patent EP1888031 A1. February 20
-
Joabsson FC, Johnsson MC, Tiberg FC, inventors; Camurus AB, Goddard C, applicants. GLP-1 analogue formulations. European patent EP1888031 A1. February 20, 2008.
-
(2008)
February
-
-
Joabsson, F.C.1
Johnsson, M.C.2
Tiberg, F.C.3
Camurus, A.B.4
Goddard, C.5
-
38
-
-
0025884658
-
Reduction in defibrillator shocks with an implantable device combining antitachycardia pacing and shock therapy
-
Leitch JW, Gillis AM, Wyse DG, et al. Reduction in defibrillator shocks with an implantable device combining antitachycardia pacing and shock therapy. J Am Coll Cardiol. 1991;18(1):145-151.
-
(1991)
J Am Coll Cardiol
, vol.18
, Issue.1
, pp. 145-151
-
-
Leitch, J.W.1
Gillis, A.M.2
Wyse, D.G.3
-
40
-
-
84884217025
-
-
inventors; Endo Pharmaceuticals Solutions Inc, assignee, United State patent US20100292144 A1. November 18
-
Kuzma P, Decker S, Quandt H, inventors; Endo Pharmaceuticals Solutions Inc, assignee. Sustained delivery of exenatide and other peptides. United State patent US20100292144 A1. November 18, 2010.
-
(2010)
Sustained delivery of exenatide and other peptides
-
-
Kuzma, P.1
Decker, S.2
Quandt, H.3
-
41
-
-
33646255225
-
Polymer-drug conjugates: Progress in polymeric prodrugs
-
Khandare J, Minko T. Polymer-drug conjugates: progress in polymeric prodrugs. Prog Polym Sci. 2006;31(4):359-397.
-
(2006)
Prog Polym Sci
, vol.31
, Issue.4
, pp. 359-397
-
-
Khandare, J.1
Minko, T.2
-
42
-
-
80053597279
-
Structural modification effects on bioactivities of the novel 15-mer peptide adjuvant
-
Laman AG, Shepelyakovskaya AO, Boziev KM, et al. Structural modification effects on bioactivities of the novel 15-mer peptide adjuvant. Vaccine. 2011;29(44):7779-7784.
-
(2011)
Vaccine
, vol.29
, Issue.44
, pp. 7779-7784
-
-
Laman, A.G.1
Shepelyakovskaya, A.O.2
Boziev, K.M.3
-
43
-
-
0036784675
-
The long-acting GLP-1 derivative NN2211 ameliorates glycemia and increases beta-cell mass in diabetic mice
-
Rolin B, Larsen MO, Gotfredsen CF, et al. The long-acting GLP-1 derivative NN2211 ameliorates glycemia and increases beta-cell mass in diabetic mice. Am J Physiol Endocrinol Metab. 2002;283(4): E745-E752.
-
(2002)
Am J Physiol Endocrinol Metab
, vol.283
, Issue.4
-
-
Rolin, B.1
Larsen, M.O.2
Gotfredsen, C.F.3
-
44
-
-
33744964247
-
Design of a long acting peptide functioning as both a glucagon-like peptide-1 receptor agonist and a glucagon receptor antagonist
-
Pan CQ, Buxton JM, Yung SL, et al. Design of a long acting peptide functioning as both a glucagon-like peptide-1 receptor agonist and a glucagon receptor antagonist. J Biol Chem. 2006;281(18):12506-12515.
-
(2006)
J Biol Chem
, vol.281
, Issue.18
, pp. 12506-12515
-
-
Pan, C.Q.1
Buxton, J.M.2
Yung, S.L.3
-
45
-
-
18844427853
-
Structural and biophysical characterization of the 40 kDa PEG-interferon-alpha2a and its individual positional isomers
-
Dhalluin C, Ross A, Leuthold LA, et al. Structural and biophysical characterization of the 40 kDa PEG-interferon-alpha2a and its individual positional isomers. Bioconjug Chem. 2005;16(3):504-517.
-
(2005)
Bioconjug Chem
, vol.16
, Issue.3
, pp. 504-517
-
-
Dhalluin, C.1
Ross, A.2
Leuthold, L.A.3
-
46
-
-
0346216863
-
Chemical and biological properties of polymer-modified proteins
-
Kochendoerfer G. Chemical and biological properties of polymer-modified proteins. Expert Opin Biol Ther. 2003;3(8):1253-1261.
-
(2003)
Expert Opin Biol Ther
, vol.3
, Issue.8
, pp. 1253-1261
-
-
Kochendoerfer, G.1
-
47
-
-
77955364888
-
Effect of PEGylation on stability of peptide in poly(lactide-co-glycolide) microspheres
-
Park EJ, Tak TH, Na DH, Lee KC. Effect of PEGylation on stability of peptide in poly(lactide-co-glycolide) microspheres. Arch Pharm Res. 2010;33(7):1111-1116.
-
(2010)
Arch Pharm Res
, vol.33
, Issue.7
, pp. 1111-1116
-
-
Park, E.J.1
Tak, T.H.2
Na, D.H.3
Lee, K.C.4
-
48
-
-
26944452043
-
PEGylation, successful approach to drug delivery
-
Veronese FM, Pasut G. PEGylation, successful approach to drug delivery. Drug Discov Today. 2005;10(21):1451-1458.
-
(2005)
Drug Discov Today
, vol.10
, Issue.21
, pp. 1451-1458
-
-
Veronese, F.M.1
Pasut, G.2
-
49
-
-
0031946518
-
Short communication: Renal tubular vacuolation in animals treated with polyethylene-glycol-conjugated proteins
-
Bendele A, Seely J, Richey C, Sennello G, Shopp G. Short communication: renal tubular vacuolation in animals treated with polyethylene-glycol-conjugated proteins. Toxicol Sci. 1998;42(2):152-157.
-
(1998)
Toxicol Sci
, vol.42
, Issue.2
, pp. 152-157
-
-
Bendele, A.1
Seely, J.2
Richey, C.3
Sennello, G.4
Shopp, G.5
-
50
-
-
79954469776
-
Site-specific PEGylation of exenatide analogues markedly improved their glucoregulatory activity
-
Gong N, Ma AN, Zhang LJ, et al. Site-specific PEGylation of exenatide analogues markedly improved their glucoregulatory activity. Brit J Pharmacol. 2011;163(2):399-412.
-
(2011)
Brit J Pharmacol
, vol.163
, Issue.2
, pp. 399-412
-
-
Gong, N.1
Ma, A.N.2
Zhang, L.J.3
-
51
-
-
84884239176
-
-
inventors, Protracted exendin-4 compounds. United States patent US20110301084 A1. December 8
-
Hansen TK, Lau J, inventors; Novo Nordisk A/S, assignee. Protracted exendin-4 compounds. United States patent US20110301084 A1. December 8, 2011.
-
(2011)
Novo Nordisk A/S, Assignee
-
-
Hansen, T.K.1
Lau, J.2
-
52
-
-
71849085755
-
A recombinant polypeptide extends the in vivo half-life of peptides and proteins in a tunable manner
-
Schellenberger V, Wang CW, Geething NC, et al. A recombinant polypeptide extends the in vivo half-life of peptides and proteins in a tunable manner. Nat Biotechnol. 2009;27(12):1186-1190.
-
(2009)
Nat Biotechnol
, vol.27
, Issue.12
, pp. 1186-1190
-
-
Schellenberger, V.1
Wang, C.W.2
Geething, N.C.3
-
53
-
-
77649272159
-
Long acting hyaluronate - Exendin 4 conjugate for the treatment of type 2 diabetes
-
Kong JH, Oh EJ, Chae SY, Lee KC, Hahn SK. Long acting hyaluronate - Exendin 4 conjugate for the treatment of type 2 diabetes. Biomaterials. 2010;31(14):4121-4128.
-
(2010)
Biomaterials
, vol.31
, Issue.14
, pp. 4121-4128
-
-
Kong, J.H.1
Oh, E.J.2
Chae, S.Y.3
Lee, K.C.4
Hahn, S.K.5
-
54
-
-
76749088319
-
Biochemical, pharmaceutical and therapeutic properties of long-acting lithocholic acid derivatized exendin-4 analogs
-
Chae SY, Jin CH, Shin JH, et al. Biochemical, pharmaceutical and therapeutic properties of long-acting lithocholic acid derivatized exendin-4 analogs. J Control Release. 2010;142(2):206-213.
-
(2010)
J Control Release
, vol.142
, Issue.2
, pp. 206-213
-
-
Chae, S.Y.1
Jin, C.H.2
Shin, J.H.3
-
55
-
-
77953809853
-
The fatty acid conjugated exendin-4 analogs for type 2 antidiabetic therapeutics
-
Chae SY, Choi YG, Son S, Jung SY, Lee DS, Lee KC. The fatty acid conjugated exendin-4 analogs for type 2 antidiabetic therapeutics. J Control Release. 2010;144(1):10-16.
-
(2010)
J Control Release
, vol.144
, Issue.1
, pp. 10-16
-
-
Chae, S.Y.1
Choi, Y.G.2
Son, S.3
Jung, S.Y.4
Lee, D.S.5
Lee, K.C.6
-
56
-
-
84862809661
-
Preparation and evaluation of palmitic acid-conjugated exendin-4 with delayed absorption and prolonged circulation for longer hypoglycemia
-
Lee J, Lee C, Kim I, et al. Preparation and evaluation of palmitic acid-conjugated exendin-4 with delayed absorption and prolonged circulation for longer hypoglycemia. Int J Pharm. 2012;424(1/2):50-57.
-
(2012)
Int J Pharm
, vol.424
, Issue.1-2
, pp. 50-57
-
-
Lee, J.1
Lee, C.2
Kim, I.3
-
57
-
-
0035719828
-
The lung as a route for systemic delivery of therapeutic proteins and peptides
-
Agu RU, Ugwoke MI, Armand M, Kinget R, Verbeke N. The lung as a route for systemic delivery of therapeutic proteins and peptides. Respir Res. 2001;2(4):198-209.
-
(2001)
Respir Res
, vol.2
, Issue.4
, pp. 198-209
-
-
Agu, R.U.1
Ugwoke, M.I.2
Armand, M.3
Kinget, R.4
Verbeke, N.5
-
58
-
-
26944439522
-
The lungs as a portal of entry for systemic drug delivery
-
Patton JS, Fishburn CS, Weers JG. The lungs as a portal of entry for systemic drug delivery. Proc Am Thorac Soc. 2004;1(4):338-344.
-
(2004)
Proc Am Thorac Soc
, vol.1
, Issue.4
, pp. 338-344
-
-
Patton, J.S.1
Fishburn, C.S.2
Weers, J.G.3
-
59
-
-
79961172157
-
Albumin-coated porous hollow poly(lactic-co-glycolic acid) microparticles bound with palmityl-acylated exendin-4 as a long-acting inhalation delivery system for the treatment of diabetes
-
Kim H, Lee J, Kim TH, et al. Albumin-coated porous hollow poly(lactic-co-glycolic acid) microparticles bound with palmityl-acylated exendin-4 as a long-acting inhalation delivery system for the treatment of diabetes. Pharm Res. 2011;28(8):2008-2019.
-
(2011)
Pharm Res
, vol.28
, Issue.8
, pp. 2008-2019
-
-
Kim, H.1
Lee, J.2
Kim, T.H.3
-
60
-
-
84884268619
-
-
inventors and assignees, United States patent US20100255063 A1. October 7
-
Andersen C, Lorenzen G, Arent N, Thorengaard B, Wittorff H, inventors and assignees. Compressed chewing gum tablet. United States patent US20100255063 A1. October 7, 2010.
-
(2010)
Compressed chewing gum tablet
-
-
Andersen, C.1
Lorenzen, G.2
Arent, N.3
Thorengaard, B.4
Wittorff, H.5
-
61
-
-
84864648267
-
Delivery of two-step transcription amplification exendin-4 plasmid system with arginine-grafted bioreducible polymer in type 2 diabetes animal model
-
Kim PH, Lee M, Kim SW. Delivery of two-step transcription amplification exendin-4 plasmid system with arginine-grafted bioreducible polymer in type 2 diabetes animal model. J Control Release. 2012; 162(1):9-18.
-
(2012)
J Control Release
, vol.162
, Issue.1
, pp. 9-18
-
-
Kim, P.H.1
Lee, M.2
Kim, S.W.3
-
62
-
-
3843059231
-
Identification of CJC-1131-albumin bioconjugate as a stable and bioactive GLP-1(7-36) analog
-
Léger R, Thibaudeau K, Robitaille M, et al. Identification of CJC-1131-albumin bioconjugate as a stable and bioactive GLP-1(7-36) analog. Bioorg Med Chem Lett. 2004;14(17):4395-4398.
-
(2004)
Bioorg Med Chem Lett
, vol.14
, Issue.17
, pp. 4395-4398
-
-
Léger, R.1
Thibaudeau, K.2
Robitaille, M.3
-
63
-
-
84874245248
-
Injectable protease-operated depots of glucagon-like peptide-1 provide extended and tunable glucose control
-
Amiram M, Luginbuhl KM, Li X, Feinglos MN, Chilkoti A. Injectable protease-operated depots of glucagon-like peptide-1 provide extended and tunable glucose control. Proc Natl Acad Sci U S A. 2013;110(8):2792-2797.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, Issue.8
, pp. 2792-2797
-
-
Amiram, M.1
Luginbuhl, K.M.2
Li, X.3
Feinglos, M.N.4
Chilkoti, A.5
-
64
-
-
67649666737
-
Liraglutide once a day versus exenatide twice a day for type 2 diabetes: A 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6)
-
LEAD-6 Study Group
-
Buse JB, Rosenstock J, Sesti G, et al; LEAD-6 Study Group. Liraglutide once a day versus exenatide twice a day for type 2 diabetes: a 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6). Lancet. 2009;374(9683):39-47.
-
(2009)
Lancet
, vol.374
, Issue.9683
, pp. 39-47
-
-
Buse, J.B.1
Rosenstock, J.2
Sesti, G.3
-
65
-
-
0036189831
-
The pharmacokinetics, pharmacodynamics, safety and tolerability of NN2211, a new long-acting GLP-1 derivative, in healthy men
-
Agersø H, Jensen LB, Elbrønd B, Rolan P, Zdravkovic M. The pharmacokinetics, pharmacodynamics, safety and tolerability of NN2211, a new long-acting GLP-1 derivative, in healthy men. Diabetologia. 2002;45(2):195-202.
-
(2002)
Diabetologia
, vol.45
, Issue.2
, pp. 195-202
-
-
Agersø, H.1
Jensen, L.B.2
Elbrønd, B.3
Rolan, P.4
Zdravkovic, M.5
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