Multiplex analyses of cytokine and chemokine release from the cultured fibroblast of nasal polyps: The effect of IL-17A

Acta Oto-Laryngologica

Volumn 133, Issue 10, 2013, Pages 1065-1072

  Homma, Hirotomo ^a   Kamiya, Kazusaku ^a   Kusunoki, Takeshi ^a   Ikeda, Katsuhisa ^a  

^a JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Basic FGF; Chronic rhinosinusitis; G CSF; IL 6; IL 9; MCP 1

Indexed keywords

CHEMOKINE; CYTOKINE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 15; INTERLEUKIN 17; INTERLEUKIN 17 RECEPTOR; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 7; INTERLEUKIN 8; INTERLEUKIN 9; MACROPHAGE INFLAMMATORY PROTEIN 1; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MONOCYTE CHEMOTACTIC PROTEIN 1; PLATELET DERIVED GROWTH FACTOR; RANTES; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

ADULT; AGED; ARTICLE; CHRONIC RHINOSINUSITIS; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; EOSINOPHIL COUNT; FEMALE; FIBROBLAST CULTURE; GENE EXPRESSION; HUMAN; HUMAN CELL; MALE; NOSE POLYP; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SUPERNATANT; TARGET CELL; UPREGULATION;

ADULT; AGED; CELLS, CULTURED; CHEMOKINES; CYTOKINES; FEMALE; FIBROBLASTS; GENE EXPRESSION REGULATION; HUMANS; IMMUNOASSAY; INTERLEUKIN-17; MALE; MIDDLE AGED; NASAL POLYPS; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; YOUNG ADULT;

EID: 84884237887     PISSN: 00016489     EISSN: 16512251     Source Type: Journal    
DOI: 10.3109/00016489.2013.796091     Document Type: Article

References (20)

1. Fokkens W, Lund V, Mullol J, Bachert C, Alobid I, Baroody F, et al. European position paper on rhinosinusitis and nasal polyps 2012. Rhinology 2012;50:51-298.
2. Nonaka M, Ogihara N, Fukumoto A, Sakanushi A, Kusama K, Pawankar R, et al. Combined stimulation with poly(I:C), TNF-alpha and Th2 cytokines induces tarc production by human fibroblasts from the nose, bronchioles and lungs. Int Arch Allergy Immunol 2010;152:327-41.
3. Yao Z, Fanslow WC, Seldin MF, Rousseau AM, Painter SL, Comeau MR, et al. Herpesvirus saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor. Immunity 1995;3:811-21.
4. Molet S, Hamid Q, Davoine F, Nutku E, Taha R, Page N, et al. IL-17 is increased in asthmatic airways and induces human bronchial fibroblasts to produce cytokines. J Allergy Clin Immunol 2001;108:430-8.
5. Bettelli E, Carrier Y, Gao W, Korn T, Strom TB, Oukka M, et al. Reciprocal developmental pathways for the generation of pathogenic effector Th17 and regulatory T cells. Nature 2006;441:235-8.
6. SaitohT,KusunokiT,YaoT,KawanoK,KojimaY,MiyaharaK, et al. Relationship between epithelial damage or basement membrane thickness and eosinophilic infiltration in nasal polyps with chronic rhinosinusitis. Rhinology 2009;47:275-9.
7. Saitoh T, Kusunoki T, Yao T, Kawano K, Kojima Y, Miyahara K, et al. Role of interleukin-17A in the eosinophil accumulation and mucosal remodeling in chronic rhinosinusitis with nasal polyps associated with asthma. Int Arch Allergy Immunol 2010;151:8-16.
8. Makihara S, Okano M, Fujiwara T, Kariya S, Noda Y, Higaki T, et al. Regulation and characterization of IL-17- A expression in patients with chronic rhinosinusitis and its relationship with eosinophilic inflammation. J Allergy Clin Immunol 2010;126:397-400, 400.e1-11.
9. Ikeda K, Kondo Y, Sunose H, Hirano K, Oshima T, Shimomura A, et al. Subjective and objective evaluation in endoscopic sinus surgery. Am J Rhinol 1996;10:217-20.
10. Lund VJ, Kennedy DW. Staging for rhinosinusitis. Otolaryngol Head Neck Surg 1997;117:S35-40.
11. Romagnani S. Cytokines and chemoattractants in allergic inflammation. Mol Immunol 2002;38:881-5.
12. Ono N, Kusunoki T, Ikeda K. Relationships between IL-17- A and macrophages or MUC5AC in eosinophilic chronic rhinosinusitis and proposed pathological significance. Allergy Rhinol (Providence) 2012;3:50-4.
13. Peters AT, Kato A, Zhang N, Conley DB, Suh L, Tancowny B, et al. Evidence for altered activity of the IL-6- pathway in chronic rhinosinusitis with nasal polyps. J Allergy Clin Immunol 2010;125:397-403.e10.
14. Steinke JW, Crouse CD, Bradley D, Hise K, Lynch K, Kountakis SE, et al. Characterization of interleukin-4- stimulated nasal polyp fibroblasts. Am J Respir Cell Mol Biol 2004;30:212-19.
15. Gounni AS, Gregory B, Nutku E, Aris F, Latifa K, Minshall E, et al. Interleukin-9 enhances interleukin-5- receptor expression, differentiation, and survival of human eosinophils. Blood 2000;96:2163-71.
16. Little FF, Cruikshank WW, Center DM. IL-9 stimulates release of chemotactic factors from human bronchial epithelial cells. Am J Respir Cell Mol Biol 2001;25:347-52.
17. Yao T,Kojima Y,Koyanagi A, YokoiH, SaitoT,KawanoK, et al. Eotaxin-1, -2, and -3 immunoreactivity and protein concentration in the nasal polyps of eosinophilic chronic rhinosinusitis patients. Laryngoscope 2009;119:1053-9.
18. Sampson AP. The role of eosinophils and neutrophils in inflammation. Clin Exp Allergy 2000;30:22-7.
19. Suzuki H, Ikeda K. Mode of action of long-term low-dose macrolide therapy for chronic sinusitis in the light of neutrophil recruitment.CurrDrugTargets InflammAllergy2002;1:117-26.
20. Langrish CL, Chen Y, Blumenschein WM, Mattson J, Basham B, Sedgwick JD, et al. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J Exp Med 2005;201:233-40.