Synthesis and biological evaluation of α-galactosylceramide analogues with heteroaromatic rings and varying positions of a phenyl group in the sphingosine backbone

Journal of Medicinal Chemistry

Volumn 56, Issue 17, 2013, Pages 7100-7109

  Kim, Yongju ^a   Oh, Keunhee ^b   Song, Heebum ^a   Lee, Dong Sup ^b   Park, Seung Bum ^a  

^a Seoul National University   (South Korea)

^b Seoul National University College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

1 O (ALPHA GALACTOPYRANOSYL) 2 HEXACOSANOYLAMINO 1,3,4 OCTADECANETRIOL; ALPHA GALACTOSYLCERAMIDE; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 4; PHENYL GROUP; PYRAZOLE; SPHINGOSINE;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; AUTOIMMUNE DISEASE; CONTROLLED STUDY; CYTOKINE RELEASE; DEMYELINATING DISEASE; DRUG DESIGN; DRUG SCREENING; DRUG SYNTHESIS; IMMUNOMODULATION; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PATHOGENESIS; POLARIZATION; STRUCTURE ACTIVITY RELATION; TH1 CELL; TH17 CELL;

ANIMALS; GALACTOSYLCERAMIDES; MAGNETIC RESONANCE SPECTROSCOPY; MICE; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPHINGOSINE;

EID: 84884235633     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm400949h     Document Type: Article

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