Upregulation of mGlu2 receptors via NF-κB p65 acetylation is involved in the proneurogenic and antidepressant effects of acetyl-L-carnitine

Neuropsychopharmacology

Volumn 38, Issue 11, 2013, Pages 2220-2230

  Cuccurazzu, Bruna ^a   Bortolotto, Valeria ^a   Valente, Maria Maddalena ^a   Ubezio, Federica ^a   Koverech, Aleardo ^b   Canonico, Pier Luigi ^a   Grilli, Mariagrazia ^a,b  

^a UNIVERSITY OF EASTERN PIEDMONT   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Acetyl L carnitine; Depression; MGlu receptors; Neurogenesis; NF B

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LEVACECARNINE; METABOTROPIC RECEPTOR 2; MICROTUBULE ASSOCIATED PROTEIN 2; NESTIN; SYNAPTOTAGMIN I;

ACETYLATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDEPRESSANT ACTIVITY; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; HIPPOCAMPUS; IN VITRO STUDY; IN VIVO STUDY; MALE; MOLECULE; MOUSE; NERVE CELL; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION;

ACETYLATION; ACETYLCARNITINE; ANIMALS; ANTIDEPRESSIVE AGENTS; CELLS, CULTURED; CHOICE BEHAVIOR; HIPPOCAMPUS; IMMOBILITY RESPONSE, TONIC; MALE; MICE; NEUROGENESIS; RECEPTORS, METABOTROPIC GLUTAMATE; STEM CELLS; TRANSCRIPTION FACTOR RELA; UP-REGULATION;

EID: 84884233351     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2013.121     Document Type: Article

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