Impairment of synaptic plasticity by the stress mediator CRH involves selective destruction of thin dendritic spines via RhoA signaling

Molecular Psychiatry

Volumn 18, Issue 4, 2013, Pages 485-496

  Chen, Y ^a   Kramar E A ^b   Chen, L Y ^b   Babayan, A H ^b   Andres, A L ^b   Gall, C M ^b   Lynch, G ^b   Baram, T Z ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

CRF; CRF receptor; memory; spine; synapse; synaptic plasticity

Indexed keywords

CORTICOTROPIN RELEASING FACTOR; F ACTIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CELL SUBPOPULATION; DENDRITIC SPINE; ELECTROPHYSIOLOGY; HIPPOCAMPUS; IMAGE ANALYSIS; IMMUNOCYTOCHEMISTRY; MENTAL STRESS; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; SYNAPTIC TRANSMISSION; TRANSGENIC MOUSE;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ACTINS; ANIMALS; CORTICOTROPIN-RELEASING HORMONE; DENDRITIC SPINES; EXCITATORY POSTSYNAPTIC POTENTIALS; HIPPOCAMPUS; HUMANS; MALE; MICE; NEURONAL PLASTICITY; PROTEIN KINASE INHIBITORS; RATS; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION; SYNAPSES; SYNAPTIC TRANSMISSION;

EID: 84884211361     PISSN: 13594184     EISSN: 14765578     Source Type: Journal    
DOI: 10.1038/mp.2012.17     Document Type: Article

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