Brain targeting of olanzapine via intranasal delivery of core-shell difunctional block copolymer mixed nanomicellar carriers: In vitro characterization, ex vivo estimation of nasal toxicity and in vivo biodistribution studies

International Journal of Pharmaceutics

Volumn 452, Issue 1-2, 2013, Pages 300-310

  Abdelbary, Ghada Ahmed ^a   Tadros, Mina Ibrahim ^a  

^a CAIRO UNIVERSITY   (Egypt)

Author keywords

In vivo biodistribution; Nose to brain delivery; Olanzapine; Polymeric mixed micelles; Radiolabeling

Indexed keywords

COPOLYMER; F11 TC 99M; NANOCARRIER; OLANZAPINE; OLANZAPINE TC 99M; POLOXAMER; TECHNETIUM; TECHNETIUM 99M; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BRAIN; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG DISTRIBUTION; DRUG TARGETING; EX VIVO STUDY; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; ISOTOPE LABELING; MALE; MICELLE; MORPHOLOGY; NONHUMAN; NOSE MUCOSA; PARTICLE SIZE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; SHEEP; TURBIDITY;

EID: 84884206762     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.04.084     Document Type: Article

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