Suppression of thioredoxin system contributes to silica-induced oxidative stress and pulmonary fibrogenesis in rats

Toxicology Letters

Volumn 222, Issue 3, 2013, Pages 289-294

  Zhu, Zhonghui ^a   Yang, Gengxia ^a   Wang, Yan ^a   Yang, Jing ^a   Gao, Ai ^a   Niu, Piye ^a   Tian, Lin ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Pulmonary fibrosis; Silica; Thioredoxin; Thioredoxin reductase

Indexed keywords

HYDROXYPROLINE; MALONALDEHYDE; REACTIVE OXYGEN METABOLITE; SILICON DIOXIDE; THIOREDOXIN; THIOREDOXIN REDUCTASE; TRANSCRIPTION FACTOR NRF2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FIBROGENESIS; HISTOPATHOLOGY; LIPID PEROXIDATION; LUNG FIBROSIS; LUNG PARENCHYMA; MALE; NONHUMAN; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SILICOSIS;

PULMONARY FIBROSIS; SILICA; THIOREDOXIN; THIOREDOXIN REDUCTASE;

ANIMALS; BLOTTING, WESTERN; HYDROXYPROLINE; LIPID PEROXIDATION; LUNG; MALE; OXIDATION-REDUCTION; OXIDATIVE STRESS; PULMONARY FIBROSIS; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SILICON DIOXIDE; SILICOSIS; THIOREDOXIN-DISULFIDE REDUCTASE; THIOREDOXINS;

EID: 84884195978     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2013.08.004     Document Type: Article

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