Phosphorylation regulates myo-inositol-3-phosphate synthase a novel regulatory mechanism of inositol biosynthesis

Journal of Biological Chemistry

Volumn 288, Issue 37, 2013, Pages 26822-26833

  Deranieh, Rania M ^a,b   He, Quan ^a   Caruso, Joseph A ^a   Greenberg, Miriam L ^a  

^a WAYNE STATE UNIVERSITY   (United States)

^b BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HUMAN DISORDERS; REGULATORY MECHANISM; SYNTHASES;

ALCOHOLS; BIOCHEMISTRY; BIOSYNTHESIS; PHOSPHORYLATION; SUGARS;

POLYOLS;

INOSITOL; MUTANT PROTEIN; MYOINOSITOL 3 PHOSPHATE SYNTHASE; PHOSPHOPROTEIN; SERINE; UNCLASSIFIED DRUG; VALPROIC ACID;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; DRUG SENSITIVITY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; ENZYME STRUCTURE; ENZYME SYNTHESIS; HUMAN; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; YEAST;

INOSITOL 1; MYO-INOSITOL PHOSPHATE SYNTHASE; PHOSPHOLIPID METABOLISM; PHOSPHORYLATION; PHOSPHORYLATION SITE MUTANTS; POST-TRANSLATIONAL MODIFICATION; VALPROATE; YEAST;

AMINO ACID SEQUENCE; BINDING SITES; CATALYSIS; ESCHERICHIA COLI; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; INOSITOL; INTRAMOLECULAR LYASES; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; PHOSPHOLIPIDS; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SERINE; VALPROIC ACID;

EID: 84884182719     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.479121     Document Type: Article

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