The effective encapsulation of a hydrophobic lipid-insoluble drug in solid lipid nanoparticles using a modified double emulsion solvent evaporation method

Colloids and Surfaces B: Biointerfaces

Volumn 112, Issue , 2013, Pages 408-414

  Nabi Meibodi, Mohsen ^a,b   Vatanara, Alireza ^a   Najafabadi, Abdolhossein Rouholamini ^a   Rouini, Mohammad Reza ^a   Ramezani, Vahid ^a,b   Gilani, Kambiz ^a   Etemadzadeh, Seyed Mohammad Hossein ^c   Azadmanesh, Kayhan ^c  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c PASTEUR INSTITUTE OF IRAN   (Iran)

Author keywords

Double emulsion solvent evaporation; Entrapment efficiency; Loading efficiency; Raloxifene HCl; Solid lipid nanoparticles

Indexed keywords

DOUBLE EMULSION-SOLVENT EVAPORATION; ENTRAPMENT EFFICIENCY; LOADING EFFICIENCY; RALOXIFENE HCL; SOLID LIPID NANOPARTICLE (SLN);

BIOCHEMISTRY; BIOMATERIALS; EMULSIFICATION; EVAPORATION; LIPIDS; SOLUBILITY; SOLVENTS; THERMOANALYSIS;

NANOPARTICLES;

METHANOL; ORGANIC SOLVENT; RALOXIFENE; SOLID LIPID NANOPARTICLE; WATER;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CELL STRAIN MCF 7; CONTROLLED STUDY; CRYSTALLIZATION; DIFFERENTIAL SCANNING CALORIMETRY; DRUG CYTOTOXICITY; DRUG FORMULATION; DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; EMULSION; EVAPORATION; HUMAN; HUMAN CELL; MODIFIED DOUBLE EMULSION SOLVENT EVAPORATION; NANOENCAPSULATION; PARTICLE SIZE; PRIORITY JOURNAL; ZETA POTENTIAL;

DOUBLE EMULSION SOLVENT EVAPORATION; ENTRAPMENT EFFICIENCY; LOADING EFFICIENCY; RALOXIFENE HCL; SOLID LIPID NANOPARTICLES;

BIOLOGICAL AVAILABILITY; BONE DENSITY CONSERVATION AGENTS; CALORIMETRY, DIFFERENTIAL SCANNING; CELL SURVIVAL; CHEMISTRY, PHARMACEUTICAL; DRUG CARRIERS; EMULSIONS; FEMALE; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LIPIDS; MCF-7 CELLS; NANOPARTICLES; PARTICLE SIZE; RALOXIFENE; SOLUBILITY;

EID: 84884172488     PISSN: 09277765     EISSN: 18734367     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2013.06.013     Document Type: Article

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