메뉴 건너뛰기




Volumn 48, Issue 11, 2013, Pages 1285-1292

Dendritic cells from the elderly display an intrinsic defect in the production of IL-10 in response to Lithium Chloride

Author keywords

Aging; Dendritic cells; Human; Lithium Chloride; TLR2; TLR4

Indexed keywords

B7 ANTIGEN; CD40 ANTIGEN; CD86 ANTIGEN; GAMMA INTERFERON; HLA DR ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 5; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; LITHIUM CHLORIDE; TOLL LIKE RECEPTOR 2 AGONIST; TOLL LIKE RECEPTOR 4 AGONIST; TOLL LIKE RECEPTOR AGONIST; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84884154793     PISSN: 05315565     EISSN: 18736815     Source Type: Journal    
DOI: 10.1016/j.exger.2013.08.006     Document Type: Article
Times cited : (30)

References (36)
  • 1
    • 0242580118 scopus 로고    scopus 로고
    • Cutting edge: different Toll-like receptor agonists instruct dendritic cells to induce distinct Th responses via differential modulation of extracellular signal-regulated kinase-mitogen-activated protein kinase and c-Fos
    • Agrawal S., Agrawal A., Doughty B., Gerwitz A., Blenis J., Van Dyke T., Pulendran B. Cutting edge: different Toll-like receptor agonists instruct dendritic cells to induce distinct Th responses via differential modulation of extracellular signal-regulated kinase-mitogen-activated protein kinase and c-Fos. J. Immunol. 2003, 171:4984-4989.
    • (2003) J. Immunol. , vol.171 , pp. 4984-4989
    • Agrawal, S.1    Agrawal, A.2    Doughty, B.3    Gerwitz, A.4    Blenis, J.5    Van Dyke, T.6    Pulendran, B.7
  • 2
    • 34249775503 scopus 로고    scopus 로고
    • Altered innate immune functioning of dendritic cells in elderly humans: a role of phosphoinositide 3-kinase-signaling pathway
    • Agrawal A., Agrawal S., Cao J.N., Su H., Osann K., Gupta S. Altered innate immune functioning of dendritic cells in elderly humans: a role of phosphoinositide 3-kinase-signaling pathway. J. Immunol. 2007, 178:6912-6922.
    • (2007) J. Immunol. , vol.178 , pp. 6912-6922
    • Agrawal, A.1    Agrawal, S.2    Cao, J.N.3    Su, H.4    Osann, K.5    Gupta, S.6
  • 3
    • 33846691253 scopus 로고    scopus 로고
    • Thimerosal induces TH2 responses via influencing cytokine secretion by human dendritic cells
    • Agrawal A., Kaushal P., Agrawal S., Gollapudi S., Gupta S. Thimerosal induces TH2 responses via influencing cytokine secretion by human dendritic cells. J. Leukoc. Biol. 2007, 81:474-482.
    • (2007) J. Leukoc. Biol. , vol.81 , pp. 474-482
    • Agrawal, A.1    Kaushal, P.2    Agrawal, S.3    Gollapudi, S.4    Gupta, S.5
  • 4
    • 60549108257 scopus 로고    scopus 로고
    • Increased reactivity of dendritic cells from aged subjects to self antigen, the human DNA
    • Agrawal A., Tay J., Ton S., Agrawal S., Gupta S. Increased reactivity of dendritic cells from aged subjects to self antigen, the human DNA. J. Immunol. 2009, 182:1138-1145.
    • (2009) J. Immunol. , vol.182 , pp. 1138-1145
    • Agrawal, A.1    Tay, J.2    Ton, S.3    Agrawal, S.4    Gupta, S.5
  • 5
    • 78149444089 scopus 로고    scopus 로고
    • Human dendritic cells activated via dectin-1 are efficient at priming Th17, cytotoxic CD8 T and B cell responses
    • Agrawal S., Gupta S., Agrawal A. Human dendritic cells activated via dectin-1 are efficient at priming Th17, cytotoxic CD8 T and B cell responses. PLoS One 2010, 5:e13418.
    • (2010) PLoS One , vol.5
    • Agrawal, S.1    Gupta, S.2    Agrawal, A.3
  • 6
    • 73149097234 scopus 로고    scopus 로고
    • Innate and adaptive immune responses regulated by glycogen synthase kinase-3 (GSK3)
    • Beurel E., Michalek S.M., Jope R.S. Innate and adaptive immune responses regulated by glycogen synthase kinase-3 (GSK3). Trends Immunol. 2010, 31:24-31.
    • (2010) Trends Immunol. , vol.31 , pp. 24-31
    • Beurel, E.1    Michalek, S.M.2    Jope, R.S.3
  • 7
    • 3342995295 scopus 로고    scopus 로고
    • Inflamm-aging: autoimmunity, and the immune-risk phenotype
    • Boren E., Gershwin M.E. Inflamm-aging: autoimmunity, and the immune-risk phenotype. Autoimmun. Rev. 2004, 3:401-406.
    • (2004) Autoimmun. Rev. , vol.3 , pp. 401-406
    • Boren, E.1    Gershwin, M.E.2
  • 9
    • 79954577277 scopus 로고    scopus 로고
    • TLR-signaling networks: an integration of adaptor molecules, kinases, and cross-talk
    • Brown J., Wang H., Hajishengallis G.N., Martin M. TLR-signaling networks: an integration of adaptor molecules, kinases, and cross-talk. J. Dent. Res. 2011, 90:417-427.
    • (2011) J. Dent. Res. , vol.90 , pp. 417-427
    • Brown, J.1    Wang, H.2    Hajishengallis, G.N.3    Martin, M.4
  • 15
    • 68149148866 scopus 로고    scopus 로고
    • Age-associated declines in immune system development and function: causes, consequences, and reversal
    • Dorshkind K., Swain S. Age-associated declines in immune system development and function: causes, consequences, and reversal. Curr. Opin. Immunol. 2009, 21:404-407.
    • (2009) Curr. Opin. Immunol. , vol.21 , pp. 404-407
    • Dorshkind, K.1    Swain, S.2
  • 16
    • 84856702223 scopus 로고    scopus 로고
    • Inhibition of GSK3 by lithium, from single molecules to signaling networks
    • Freland L., Beaulieu J.M. Inhibition of GSK3 by lithium, from single molecules to signaling networks. Front. Mol. Neurosci. 2012, 5:14.
    • (2012) Front. Mol. Neurosci. , vol.5 , pp. 14
    • Freland, L.1    Beaulieu, J.M.2
  • 17
    • 78249233264 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3-beta: a master regulator of toll-like receptor-mediated chronic intestinal inflammation
    • Hofmann C., Dunger N., Scholmerich J., Falk W., Obermeier F. Glycogen synthase kinase 3-beta: a master regulator of toll-like receptor-mediated chronic intestinal inflammation. Inflamm. Bowel Dis. 2010, 16:1850-1858.
    • (2010) Inflamm. Bowel Dis. , vol.16 , pp. 1850-1858
    • Hofmann, C.1    Dunger, N.2    Scholmerich, J.3    Falk, W.4    Obermeier, F.5
  • 18
    • 33646595287 scopus 로고    scopus 로고
    • IFN-gamma suppresses IL-10 production and synergizes with TLR2 by regulating GSK3 and CREB/AP-1 proteins
    • Hu X., Paik P.K., Chen J., Yarilina A., Kockeritz L., Lu T.T., Woodgett J.R., Ivashkiv L.B. IFN-gamma suppresses IL-10 production and synergizes with TLR2 by regulating GSK3 and CREB/AP-1 proteins. Immunity 2006, 24:563-574.
    • (2006) Immunity , vol.24 , pp. 563-574
    • Hu, X.1    Paik, P.K.2    Chen, J.3    Yarilina, A.4    Kockeritz, L.5    Lu, T.T.6    Woodgett, J.R.7    Ivashkiv, L.B.8
  • 19
    • 84860330618 scopus 로고    scopus 로고
    • Role of interleukin 10 transcriptional regulation in inflammation and autoimmune disease
    • Iyer S.S., Cheng G. Role of interleukin 10 transcriptional regulation in inflammation and autoimmune disease. Crit. Rev. Immunol. 2012, 32:23-63.
    • (2012) Crit. Rev. Immunol. , vol.32 , pp. 23-63
    • Iyer, S.S.1    Cheng, G.2
  • 20
    • 77951260924 scopus 로고    scopus 로고
    • The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
    • Kawai T., Akira S. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat. Immunol. 2010, 11:373-384.
    • (2010) Nat. Immunol. , vol.11 , pp. 373-384
    • Kawai, T.1    Akira, S.2
  • 24
    • 69949083414 scopus 로고    scopus 로고
    • Modulation of adaptive immunity with Toll-like receptors
    • Manicassamy S., Pulendran B. Modulation of adaptive immunity with Toll-like receptors. Semin. Immunol. 2009, 21:185-193.
    • (2009) Semin. Immunol. , vol.21 , pp. 185-193
    • Manicassamy, S.1    Pulendran, B.2
  • 25
    • 23944486750 scopus 로고    scopus 로고
    • Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3
    • Martin M., Rehani K., Jope R.S., Michalek S.M. Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3. Nat. Immunol. 2005, 6:777-784.
    • (2005) Nat. Immunol. , vol.6 , pp. 777-784
    • Martin, M.1    Rehani, K.2    Jope, R.S.3    Michalek, S.M.4
  • 26
    • 68149179573 scopus 로고    scopus 로고
    • Immunosenescence: what does it mean to health outcomes in older adults?
    • McElhaney J.E., Effros R.B. Immunosenescence: what does it mean to health outcomes in older adults?. Curr. Opin. Immunol. 2009, 21:418-424.
    • (2009) Curr. Opin. Immunol. , vol.21 , pp. 418-424
    • McElhaney, J.E.1    Effros, R.B.2
  • 27
    • 33846271107 scopus 로고    scopus 로고
    • Erythrocyte phosphoglucomutase activity of bipolar I patients currently using lithium or carbamazepine
    • Montero-Lomeli M., Galvao D., Morais B.B., Nardi A.E. Erythrocyte phosphoglucomutase activity of bipolar I patients currently using lithium or carbamazepine. Braz J Med Biol Res. 2007, 40:19-25.
    • (2007) Braz J Med Biol Res. , vol.40 , pp. 19-25
    • Montero-Lomeli, M.1    Galvao, D.2    Morais, B.B.3    Nardi, A.E.4
  • 29
    • 84866528957 scopus 로고    scopus 로고
    • Restraint of inflammatory signaling by interdependent strata of negative regulatory pathways
    • Murray P.J., Smale S.T. Restraint of inflammatory signaling by interdependent strata of negative regulatory pathways. Nat. Immunol. 2012, 13:916-924.
    • (2012) Nat. Immunol. , vol.13 , pp. 916-924
    • Murray, P.J.1    Smale, S.T.2
  • 30
    • 77649184739 scopus 로고    scopus 로고
    • The regulation of IL-10 production by immune cells
    • Saraiva M., O'Garra A. The regulation of IL-10 production by immune cells. Nat. Rev. Immunol. 2010, 10:170-181.
    • (2010) Nat. Rev. Immunol. , vol.10 , pp. 170-181
    • Saraiva, M.1    O'Garra, A.2
  • 31
    • 77952487841 scopus 로고    scopus 로고
    • Role of glycogen synthase kinase 3 (GSK-3) in innate immune response of human immature dendritic cells to Aspergillus fumigatus
    • Spinnler K., Mezger M., Steffens M., Sennefelder H., Kurzai O., Einsele H., Loeffler J. Role of glycogen synthase kinase 3 (GSK-3) in innate immune response of human immature dendritic cells to Aspergillus fumigatus. Med Mycol. 2010, 48:589-597.
    • (2010) Med Mycol. , vol.48 , pp. 589-597
    • Spinnler, K.1    Mezger, M.2    Steffens, M.3    Sennefelder, H.4    Kurzai, O.5    Einsele, H.6    Loeffler, J.7
  • 32
    • 78651075836 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3: a point of convergence for the host inflammatory response
    • Wang H., Brown J., Martin M. Glycogen synthase kinase 3: a point of convergence for the host inflammatory response. Cytokine 2011, 53:130-140.
    • (2011) Cytokine , vol.53 , pp. 130-140
    • Wang, H.1    Brown, J.2    Martin, M.3
  • 34
    • 23944499155 scopus 로고    scopus 로고
    • GSK3: an in-Toll-erant protein kinase?
    • Woodgett J.R., Ohashi P.S. GSK3: an in-Toll-erant protein kinase?. Nat. Immunol. 2005, 6:751-752.
    • (2005) Nat. Immunol. , vol.6 , pp. 751-752
    • Woodgett, J.R.1    Ohashi, P.S.2
  • 35
    • 79959276349 scopus 로고    scopus 로고
    • Long-term treatment with lithium alleviates memory deficits and reduces amyloid-beta production in an aged Alzheimer's disease transgenic mouse model
    • Zhang X., Heng X., Li T., Li L., Yang D., Du Y., Doody R.S., Le W. Long-term treatment with lithium alleviates memory deficits and reduces amyloid-beta production in an aged Alzheimer's disease transgenic mouse model. J. Alzheimers Dis. 2011, 24:739-749.
    • (2011) J. Alzheimers Dis. , vol.24 , pp. 739-749
    • Zhang, X.1    Heng, X.2    Li, T.3    Li, L.4    Yang, D.5    Du, Y.6    Doody, R.S.7    Le, W.8
  • 36
    • 77952313777 scopus 로고    scopus 로고
    • Differentiation of effector CD4 T cell populations (*)
    • Zhu J., Yamane H., Paul W.E. Differentiation of effector CD4 T cell populations (*). Annu. Rev. Immunol. 2010, 28:445-489.
    • (2010) Annu. Rev. Immunol. , vol.28 , pp. 445-489
    • Zhu, J.1    Yamane, H.2    Paul, W.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.