Functional MRI of sentence-level language comprehension in schizophrenia: A coordinate-based analysis

Schizophrenia Research

Volumn 150, Issue 1, 2013, Pages 107-113

  Rapp, Alexander M ^a   Steinhäuser, Anne E ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Auditory verbal hallucinations; Hayling task; Laterality; Lateralization; Prefrontal; Temporal; Thought disorder

Indexed keywords

ARTICLE; BRAIN REGION; COMPREHENSION; FUNCTIONAL ASSESSMENT; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HEMISPHERIC DOMINANCE; HUMAN; LANGUAGE ABILITY; LEFT HEMISPHERE; MENTAL FUNCTION; PREFRONTAL CORTEX; PREMOTOR CORTEX; PRIORITY JOURNAL; RIGHT HEMISPHERE; SCHIZOPHRENIA; SYSTEMATIC REVIEW; TEMPORAL GYRUS; TEMPORAL LOBE; THOUGHT DISORDER;

AUDITORY VERBAL HALLUCINATIONS; HAYLING TASK; LATERALITY; LATERALIZATION; PREFRONTAL; TEMPORAL; THOUGHT DISORDER;

BRAIN; BRAIN MAPPING; COMPREHENSION; DATABASES, BIBLIOGRAPHIC; FEMALE; FUNCTIONAL LATERALITY; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; LANGUAGE DISORDERS; MAGNETIC RESONANCE IMAGING; MALE; OXYGEN; SCHIZOPHRENIA; SEMANTICS;

EID: 84884138680     PISSN: 09209964     EISSN: 15732509     Source Type: Journal    
DOI: 10.1016/j.schres.2013.07.019     Document Type: Article

References (88)

1. Abdul-Rahman M.F., Qiu A., Woon P.S., Kuswanto C., Collinson S.L., Sim K. Arcuate fasciculus abnormalities and their relationship with psychotic symptoms in schizophrenia. PLoS One 2012, 7(1):e29315. 10.1371/journal.pone.0029315.
2. Allen P., Modinos G., Hubl D., Shields G., Cachia A., Jardri R., Thomas P., Woodward T., Shotbolt P., Plaze M., Hoffman R. Neuroimaging auditory hallucinations in schizophrenia: from neuroanatomy to neurochemistry and beyond. Schizophr. Bull. 2012, 38(4):695-703.
3. Arcuri S.M. Neural and Cognitive Studies of Thought Disorder in Schizophrenia 2003, Thesis (PhD), University of London, Kings College London, Institute of Psychiatry.
4. Arcuri S.M., Broome M.R., Giampietro V., Amaro E., Kircher T.T., Williams S.C., Andrew C.M., Brammer M., Morris R.G., McGuire P.K. Faulty suppression of irrelevant material in patients with thought disorder linked to attenuated frontotemporal activation. Schizophr. Res. Treat. 2012, 2012:176290.
5. Barta P.E., Pearlson G.D., Brill L.B., Royall R., McGilchrist I.K., Pulver A.E., Powers R.E., Casanova M.F., Tien A.Y., Frangou S., Petty R.G. Planum temporale asymmetry reversal in schizophrenia: replication and relationship to gray matter abnormalities. Am. J. Psychiatry 1997, 154(5):661-667.
6. Binder J.R., Desai R.H., Graves W.W., Conant L.L. Where is the semantic system? A critical review and meta-analysis of 120 functional neuroimaging studies. Cereb. Cortex 2009, 19(12):2767-2796.
7. Bleuler E. Die Schizophrenien (dementia praecox). Lehrbuch der Psychiatrie 1920, 278-331. Verlag Julius Springer, Berlin. 3rd ed. E. Bleuler (Ed.).
8. Borofsky L.A., McNealy K., Siddarth P., Wu K.N., Dapretto M., Caplan R. Semantic processing and thought disorder in childhood-onset schizophrenia: insights from fMRI. J. Neurolinguistics 2010, 23(3):204-222.
9. Burgess P.W., Shallice T. Response suppression, initiation and strategy use following frontal lobe lesions. Neuropsychologia 1996, 34(4):263-272.
10. Cannon M., Caspi A., Moffitt T.E., Harrington H., Taylor A., Murray R.M., Poulton R. Evidence for early-childhood, pan-developmental impairment specific to schizophreniform disorder: results from a longitudinal birth cohort. Arch. Gen. Psychiatry 2002, 59(5):449-456.
11. Carp J. On the plurality of (methodological) worlds: estimating the analytic flexibility of FMRI experiments. Front. Neurosci. 2012, 6:149. (Epub 2012 Oct 11). 10.3389/fnins.2012.00149.
12. Catani M., Craig M.C., Forkel S.J., Kanaan R., Picchioni M., Toulopoulou T., Shergill S., Williams S., Murphy D.G., McGuire P. Altered integrity of perisylvian language pathways in schizophrenia: relationship to auditory hallucinations. Biol. Psychiatry 2011, 70(12):1143-1150.
13. Chan R.C., Di X., McAlonan G.M., Gong Q.Y. Brain anatomical abnormalities in high-risk individuals, first-episode, and chronic schizophrenia: an activation likelihood estimation meta-analysis of illness progression. Schizophr. Bull. 2011, 37(1):177-188.
14. Chance S.A., Casanova M.F., Switala A.E., Crow T.J. Auditory cortex asymmetry, altered minicolumn spacing and absence of ageing effects in schizophrenia. Brain 2008, 131(Pt 12):3178-3192.
15. Condray R., Steinhauer S.R., Goldstein G. Language comprehension in schizophrenics and their brothers. Biol. Psychiatry 1992, 32(9):790-802.
16. Condray R., van-Kammen D.P., Steinhauer S.R., Kasparek A., Yao J.K. Language comprehension in schizophrenia: trait or state indicator?. Biol. Psychiatry 1995, 38:287-296.
17. Condray R., Steinhauer S.R., van-Kammen D.P., Kasparek A. The language system in schizophrenia: effects of capacity and linguistic structure. Schizophr. Bull. 2002, 28:475-490.
18. Crow T.J. Is schizophrenia the price that Homo sapiens pays for language?. Schizophr. Res. 1997, 28:127-141.
19. Crow T.J. Schizophrenia as failure of hemispheric dominance for language. Trends Neurosci. 1997, 20:339-343.
20. Crow T.J. Schizophrenia as the price that Homo sapiens pays for language: a resolution of the central paradox in the origin of the species. Brain Res. Brain Res. Rev. 2000, 31(2-3):118-129.
21. Crow T.J. Auditory hallucinations as primary disorders of syntax: an evolutionary theory of the origins of language. Cogn. Neuropsychiatry 2004, 9(1-2):125-145.
22. Crow T.J. The nuclear symptoms of schizophrenia reveal the four quadrant structure of language and its deictic frame. J. Neurolinguistics 2010, 23(1):1-9.
23. Curcic-Blake B., Liemburg E., Vercammen A., Swart M., Knegtering H., Bruggeman R., Aleman A. When broca goes uninformed: reduced information flow to broca's area in schizophrenia patients with auditory hallucinations. Schizophr. Bull. Oct. 15 2013, (in press). 10.1093/schbul/sbs107.
24. David A.S. The cognitive neuropsychiatry of auditory verbal hallucinations: an overview. Cogn. Neuropsychiatry 2004, 9(1-2):107-123.
25. de Weijer A.D., Mandl R.C., Diederen K.M., Neggers S.F., Kahn R.S., Hulshoff Pol H.E., Sommer I.E. Microstructural alterations of the arcuate fasciculus in schizophrenia patients with frequent auditory verbal hallucinations. Schizophr. Res. 2011, 130(1-3):68-77.
26. de Weijer A.D., Neggers S.F., Diederen K.M., Mandl R.C., Kahn R.S., Hulshoff Pol H.E., Sommer I.E. Aberrations in the arcuate fasciculus are associated with auditory verbal hallucinations in psychotic and in non-psychotic individuals. Hum. Brain Mapp. 2013, 34(3):626-634.
27. DeLisi L.E. Speech disorder in schizophrenia: review of the literature and new study of the relation to uniquely human capacity for language. Schizophr. Bull. 2001, 27(3):481-496.
28. Docherty N.M. Communication disturbances in schizophrenia: a two-process formulation. Compr. Psychiatry 1995, 36(3):182-186.
29. Dollfus S., Razafimandimby A., Delamillieure P., Brazo P., Joliot M., Mazoyer B., Tzourio-Mazoyer N. Atypical hemispheric specialization for language in right-handed schizophrenia patients. Biol. Psychiatry 2005, 57(9):1020-1028.
30. Dollfus S., Razafimandimby A., Maïza O., Lebain P., Brazo P., Beaucousin V., Lecardeur L., Delamillieure P., Mazoyer B., Tzourio-Mazoyer N. Functional deficit in the medial prefrontal cortex during a language comprehension task in patients with schizophrenia. Schizophr. Res. 2008, 99(1-3):304-311.
31. Eickhoff S.B., Laird A.R., Grefkes C., Wang L.E., Zilles K., Fox P.T. Coordinate-based activation likelihood estimation meta-analysis of neuroimaging data: a random-effects approach based on empirical estimates of spatial uncertainty. Hum. Brain Mapp. 2009, 30(9):2907-2926.
32. Faber R., Abrams R., Taylor M.A., Kasprison A., Morris C., Weisz R. Comparison of schizophrenic patients with formal thought disorder and neurologically impaired patients with aphasia. Am. J. Psychiatry 1983, 140:1348-1351.
33. Faust M. Neuropsychology of Language: Advances in the Neural Substrates of Language: Toward a Synthesis of Basic Research and Clinical Research 2012, Wiley-Blackwell.
34. Fuller R., Nopoulos P., Arndt S., O'Leary D., Ho B.C., Andreasen N.C. Longitudinal assessment of premorbid cognitive functioning in patients with schizophrenia through examination of standardized scholastic test performance. Am. J. Psychiatry 2002, 159(7):1183-1189.
35. Grosselin A., Royer A., Schneider F.C., Brouillet D., Martin S., Pellet J., Lang F., Massoubre C. Inhibition des réponses automatiques au test du Hayling dans la schizophrénie. Encephale 2010, 36(4):277-284.
36. Grove W.M., Andreasen N.C. Language and thinking in psychosis. Is there an input abnormality?. Arch. Gen. Psychiatry 1985, 42(1):26-32.
37. Hasan A., Kremer L., Gruber O., Schneider-Axmann T., Guse B., Reith W., Falkai P., Wobrock T. Planum temporale asymmetry to the right hemisphere in first-episode schizophrenia. Psychiatry Res. 2011, 193(1):56-59.
38. Hayes R.L., O'Grady B.M. Do people with schizophrenia comprehend what they read?. Schizophr. Bull. 2003, 29(3):499-507.
39. Heckers S. Neuropathology of schizophrenia: cortex, thalamus, basal ganglia, and neurotransmitter-specific projection systems. Schizophr. Bull. 1997, 23(3):403-421.
40. Horn H., Jann K., Federspiel A., Walther S., Wiest R., Müller T., Strik W. Semantic network disconnection in formal thought disorder. Neuropsychobiology 2012, 66(1):14-23.
41. Hubl D., Koenig T., Strik W., Federspiel A., Kreis R., Boesch C., Maier S.E., Schroth G., Lovblad K., Dierks T. Pathways that make voices: white matter changes in auditory hallucinations. Arch. Gen. Psychiatry 2004, 61(7):658-668.
42. Jaspers K. Allgemeine Psychopathologie. Sechste unveränderte Auflage 1953, 160-163. Springer, Berlin Göttingen Heidelberg.
43. Language and Thought in Schizophrenia 1944, University of California Press, Berkeley, CA, US. J.S. Kasanin (Ed.).
44. Kircher T.T.J., Bullmore E.T., Brammer M.J., Williams S.C.R., Broome M.R., Murray R.M., McGuire P.K. Differential activation of temporal cortex during sentence completion in schizophrenic patients with and without formal thought disorder. Schizophr. Res. 2001, 50:27-40.
45. Kircher T.T.J., Liddle P.F., Brammer M.J., Williams S.C.R., Murray R.M., McGuire P.K. Reversed lateralisation of temporal activation during speech production in thought disordered patients with schizophrenia. Psychol. Med. 2002, 32:439-449.
46. Kircher T.T., Leube D.T., Erb M., Grodd W., Rapp A.M. Neural correlates of metaphor processing in schizophrenia. NeuroImage 2007, 34(1):281-289.
47. Kleist K. Aphasie und Geisteskrankheit. Munch. Med. Wochenschr. 1914, 61:8-12.
48. Klosterkotter J., Hellmich M., Steinmeyer E.M., Schultze-Lutter F. Diagnosing schizophrenia in the initial prodromal phase. Arch. Gen. Psychiatry 2001, 58(2):158-164.
49. Koeda M., Takahashi H., Yahata N., Matsuura M., Asai K., Okubo Y., Tanaka H. Language processing and human voice perception in schizophrenia: a functional magnetic resonance imaging study. Biol. Psychiatry 2006, 59(10):948-957.
50. Kuperberg G.R. Language in schizophrenia. Part 1: an introduction. Lang. Linguist. Compass 2010, 4(8):576-589.
51. Lawrie S.M., Buechel C., Whalley H.C., Frith C.D., Friston K.J., Johnstone E.C. Reduced frontotemporal functional connectivity in schizophrenia associated with auditory hallucinations. Biol. Psychiatry 2002, 51(12):1008-1011.
52. Li X., Branch C.A., DeLisi L.E. Language pathway abnormalities in schizophrenia: a review of fMRI and other imaging studies. Curr. Opin. Psychiatry 2009, 22(2):131-139.
53. Li X., Xia S., Bertisch H.C., Branch C.A., Delisi L.E. Unique topology of language processing brain network: a systems-level biomarker of schizophrenia. Schizophr. Res. 2012, 141(2-3):128-136.
54. Lindell A.K. In your right mind: right hemisphere contributions to language processing and production. Neuropsychol. Rev. 2006, 16(3):131-148.
55. Maïza O., Mazoyer B., Hervé P.Y., Razafimandimby A., Dollfus S., Tzourio-Mazoyer N., Andreassen O.A. Impact of cognitive performance on the reproducibility of fMRI activation in schizophrenia. J. Psychiatry Neurosci. 2010, 35(6):378-389.
56. Maïza O., Mazoyer B., Hervé P.Y., Razafimandimby A., Dollfus S., Tzourio-Mazoyer N. Reproducibility of fMRI activations during a story listening task in patients with schizophrenia. Schizophr. Res. 2011, 128(1-3):98-101.
57. McIntosh A.M., Whalley H.C., McKirdy J., Hall J., Sussmann J.E., Shankar P., Johnstone E.C., Lawrie S.M. Prefrontal function and activation in bipolar disorder and schizophrenia. Am. J. Psychiatry 2008, 165(3):378-384.
58. McKenna P.J., Oh T.M. Schizophrenic Speech. Making Sense of Bathroots and Ponds that Fall in Doorways 2005, Cambridge University Press, Cambridge, New York.
59. Mitchell R.L., Crow T.J. Right hemisphere language functions and schizophrenia: the forgotten hemisphere?. Brain 2005, 128(5):963-978.
60. Mitchell R.L., Elliott R., Barry M., Cruttenden A., Woodruff P.W. Neural response to emotional prosody in schizophrenia and in bipolar affective disorder. Br. J. Psychiatry 2004, 184:223-230.
61. Neufeld R.W. The nature of deficit among paranoid and nonparanoid schizophrenics in the interpretation of sentences: an information processing approach. J. Clin. Psychol. 1978, 34(2):333-339.
62. Nickl-Jockschat T., Schneider F., Pagel A.D., Laird A.R., Fox P.T., Eickhoff S.B. Progressive pathology is functionally linked to the domains of language and emotion: meta-analysis of brain structure changes in schizophrenia patients. Eur. Arch. Psychiatry Clin. Neurosci. 2011, 261(Suppl. 2):S166-S171.
63. Oertel V., Knöchel C., Rotarska-Jagiela A., Schönmeyer R., Lindner M., van de Ven V., Haenschel C., Uhlhaas P., Maurer K., Linden D.E. Reduced laterality as a trait marker of schizophrenia-evidence from structural and functional neuroimaging. J. Neurosci. 2010, 30(6):2289-2299.
64. Osnes B., Hugdahl K., Specht K. Effective connectivity analysis demonstrates involvement of premotor cortex during speech perception. NeuroImage 2011, 54(3):2437-2445.
65. Pearlson G.D. Superior temporal gyrus and planum temporale in schizophrenia: a selective review. Prog. Neuropsychopharmacol. Biol. Psychiatry 1997, 21(8):1203-1229.
66. Plaze M., Bartrés-Faz D., Martinot J.L., Januel D., Bellivier F., De Beaurepaire R., Chanraud S., Andoh J., Lefaucheur J.P., Artiges E., Pallier C., Paillre-Martinot M.L. Left superior temporal gyrus activation during sentence perception negatively correlates with auditory hallucination severity in schizophrenia patients. Schizophr. Res. 2006, 87(1-3):109-115.
67. Pulvermüller F., Fadiga L. Active perception: sensorimotor circuits as a cortical basis for language. Nat. Rev. Neurosci. 2010, 11:351-360.
68. Rapp A. The role of the right hemisphere for language in schizophrenia. Language Lateralization in Psychosis 2009, 147-156. Cambridge University Press, Cambridge. I.E. Sommer, R.S. Kahn (Eds.).
69. Rapp A.M., Erb M., Grodd W., Bartels M., Markert K. Neural correlates of metonymy resolution. Brain Lang. 2011, 119(3):196-205.
70. Rapp A.M., Mutschler D.E., Erb M. Where in the brain is nonliteral language? A coordinate-based meta-analysis of functional magnetic resonance imaging studies. NeuroImage 2012, 63(1):600-610.
71. Rapp A.M., Langohr K., Mutschler D.E., Erb M. Isn't it Ironic? Neural Correlates of Irony Comprehension in Schizophrenia 2013, (in press).
72. Razafimandimby A., Maiza O., Herve P.Y., Lecardeur L., Delamillieure P., Brazo P., Mazoyer B., Tzourio-Mazoyer N., Dollfus S. Stability of functional language lateralization over time in schizophrenia patients. Schizophr. Res. 2007, 94:197-206.
73. Razafimandimby A., Maïza O., Dollfus S. Functional imaging studies on language lateralization in schizophrenia patients. Language Lateralization in Psychosis 2009, 133-146. Cambridge University Press, Cambridge. I.E. Sommer, R.S. Kahn (Eds.).
74. Razafimandimby A., Tzourio-Mazoyer N., Mazoyer B., Maïza O., Dollfus S. Language lateralization in left-handed patients with schizophrenia. Neuropsychologia 2011, 49(3):313-319.
75. Reichenberg A., Weiser M., Rabinowitz J., Caspi A., Schmeidler J., Mark M., Kaplan Z., Davidson M. A population-based cohort study of premorbid intellectual, language, and behavioral functioning in patients with schizophrenia, schizoaffective disorder, and nonpsychotic bipolar disorder. Am. J. Psychiatry 2002, 159(12):2027-2035.
76. Royer A., Schneider F.C., Grosselin A., Pellet J., Barral F.G., Laurent B., Brouillet D., Lang F. Brain activation during executive processes in schizophrenia. Psychiatry Res. 2009, 173(3):170-176.
77. Saugstad L.F. A lack of cerebral lateralization in schizophrenia is within the normal variation in brain maturation but indicates late, slow maturation. Schizophr. Res. 1999, 39(3):183-196.
78. Shenton M.E., Kikinis R., Jolesz F.A., Pollak S.D., LeMay M., Wible C.G., Hokama H., Martin J., Metcalf D., Coleman M., McCarley R. Abnormalities of the left temporal lobe and thought disorder in schizophrenia. a quantitative magnetic resonance imaging study. N. Engl. J. Med. 1992, 327:604-612.
79. Language Lateralization in Psychosis 2009, Cambridge University Press, Cambridge, New York. I.E. Sommer, R.S. Kahn (Eds.).
80. Sommer I.E., Ramsey N.F., Kahn R.S. Language lateralization in schizophrenia, an fMRI study. Schizophr. Res. 2001, 52(1-2):57-67.
81. Sommer I.E., Ramsey N.F., Mandl R.C., Kahn R.S. Language lateralization in female patients with schizophrenia: an fMRI study. Schizophr. Res. 2003, 60(2-3):183-190.
82. Sommer I.E., Clos M., Meijering A.L., Diederen K.M., Eickhoff S.B. Resting state functional connectivity in patients with chronic hallucinations. PLoS One 2012, 7(9):e43516. (Epub 2012 Sep 6). 10.1371/journal.pone.0043516.
83. Strik W., Dierks T., Hubl D., Horn H. Hallucinations, thought disorders, and the language domain in schizophrenia. Clin. EEG Neurosci. 2008, 39(2):91-94.
84. Vita A., De Peri L., Deste G., Sacchetti E. Progressive loss of cortical gray matter in schizophrenia: a meta-analysis and meta-regression of longitudinal MRI studies. Transl. Psychiatry 2012, 2:e190. (2012 Nov 20).
85. Wang K., Cheung E.F., Gong Q.Y., Chan R.C. Semantic processing disturbance in patients with schizophrenia: a meta-analysis of the N400 component. PLoS One 2011, 6(10):e25435. (Epub 2011 Oct 12). 10.1371/journal.pone.0025435.
86. Weinstein S., Werker J.F., Vouloumanos A., Woodward T.S., Ngan E.T. Do you hear what I hear? Neural correlates of thought disorder during listening to speech in schizophrenia. Schizophr. Res. 2006, 86(1-3):130-137.
87. Whalley H.C., Gountouna V.E., Hall J., McIntosh A., Whyte M.C., Simonotto E., Job D.E., Owens D.G., Johnstone E.C., Lawrie S.M. Correlations between fMRI activation and individual psychotic symptoms in un-medicated subjects at high genetic risk of schizophrenia. BMC Psychiatry 2007, 7:61.
88. Wilcox J., Winokur G., Tsuang M. Predictive value of thought disorder in new-onset psychosis. Compr. Psychiatry 2012, 53(6):674-678.