The combination of two Sle2 lupus-susceptibility loci and Cdkn2c deficiency leads to T-cell-mediated pathology in B6.Faslpr mice

Genes and Immunity

Volumn 14, Issue 6, 2013, Pages 373-379

  Xu, Z ^a   Croker, B P ^a,b   Morel, L ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

CD95; congenic dissection; epistatic interaction; systemic lupus erythematosus; T cells

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; CD45 ANTIGEN; CD8 ANTIGEN; CYCLIN DEPENDENT KINASE INHIBITOR 2C; FAS ANTIGEN; HERMES ANTIGEN; MICROSATELLITE DNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN ANTIBODY COMPLEX; ARTICLE; AUTOIMMUNE DISEASE; B LYMPHOCYTE; CD3+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL INFILTRATION; CELL PROLIFERATION; CHROMOSOME 4; CONGENIC STRAIN; CONTROLLED STUDY; DERMATITIS; DISEASE SEVERITY; EPIDERMIS HYPERPLASIA; FEMALE; GENE INTERACTION; GENE LOCUS; GENE MAPPING; GENE MUTATION; GENETIC ANALYSIS; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; IMMUNOPATHOGENESIS; KIDNEY HYPERTROPHY; LUPUS ERYTHEMATOSUS NEPHRITIS; LYMPHOCYTE; MALE; MONOCYTE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEINURIA; REGULATORY T LYMPHOCYTE; SINGLE NUCLEOTIDE POLYMORPHISM; SKIN LUPUS ERYTHEMATOSUS; SKIN ULCER; SYSTEMIC LUPUS ERYTHEMATOSUS; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION;

MUS;

ANIMALS; ANTIGENS, CD95; CHROMOSOME MAPPING; CYCLIN-DEPENDENT KINASE INHIBITOR P18; EPISTASIS, GENETIC; GENETIC LOCI; GENETIC PREDISPOSITION TO DISEASE; KIDNEY; LUPUS ERYTHEMATOSUS, SYSTEMIC; MICE; SKIN; T-LYMPHOCYTE SUBSETS;

EID: 84883898226     PISSN: 14664879     EISSN: 14765470     Source Type: Journal    
DOI: 10.1038/gene.2013.28     Document Type: Article

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