메뉴 건너뛰기




Volumn 38, Issue 10, 2013, Pages 2184-2195

Oxytocinergic manipulations in corticolimbic circuit differentially affect fear acquisition and extinction

Author keywords

Amygdala; Anxiety; Extinction; Fear; Oxytocin; Prefrontal; Regulation

Indexed keywords

OXYTOCIN;

EID: 84883860786     PISSN: 03064530     EISSN: 18733360     Source Type: Journal    
DOI: 10.1016/j.psyneuen.2013.04.006     Document Type: Article
Times cited : (70)

References (67)
  • 1
    • 33644943823 scopus 로고    scopus 로고
    • GABAA agonist to the infralimbic prefrontal cortex or the basolateral amygdala facilitates extinction of conditioned fear
    • Akirav I., Raizel H., Maroun M. GABAA agonist to the infralimbic prefrontal cortex or the basolateral amygdala facilitates extinction of conditioned fear. Eur J Neurosci 2006, 23:758-764.
    • (2006) Eur J Neurosci , vol.23 , pp. 758-764
    • Akirav, I.1    Raizel, H.2    Maroun, M.3
  • 2
    • 70350644903 scopus 로고    scopus 로고
    • D-Cycloserine into the BLA reverses the impairing effects of exposure to stress on the extinction of contextual fear, but not conditioned taste aversion
    • Akirav I., Segev A., Motanis H., Maroun M. d-Cycloserine into the BLA reverses the impairing effects of exposure to stress on the extinction of contextual fear, but not conditioned taste aversion. Learn. Mem. 2009, 16:682-686.
    • (2009) Learn. Mem. , vol.16 , pp. 682-686
    • Akirav, I.1    Segev, A.2    Motanis, H.3    Maroun, M.4
  • 3
    • 34548790136 scopus 로고    scopus 로고
    • The role of the medial prefrontal cortex-amygdala circuit in stress effects on the extinction of fear
    • Akirav I., Maroun M. The role of the medial prefrontal cortex-amygdala circuit in stress effects on the extinction of fear. Neural Plast. 2007, 2007:30873.
    • (2007) Neural Plast. , vol.2007 , pp. 30873
    • Akirav, I.1    Maroun, M.2
  • 4
    • 33747066840 scopus 로고    scopus 로고
    • The role of the amygdala in the extinction of conditioned fear
    • Barad M., Gean P.W., Lutz B. The role of the amygdala in the extinction of conditioned fear. Biol. Psychiatry 2006, 60(4):322-328.
    • (2006) Biol. Psychiatry , vol.60 , Issue.4 , pp. 322-328
    • Barad, M.1    Gean, P.W.2    Lutz, B.3
  • 5
    • 79959874788 scopus 로고    scopus 로고
    • Social effects of oxytocin in humans: context and person matter
    • Bartz J.A., Zaki J., Bolger N., Ochsner K.N. Social effects of oxytocin in humans: context and person matter. Trends Cogn. Sci. 2011, 15:301-309.
    • (2011) Trends Cogn. Sci. , vol.15 , pp. 301-309
    • Bartz, J.A.1    Zaki, J.2    Bolger, N.3    Ochsner, K.N.4
  • 6
    • 47549108063 scopus 로고    scopus 로고
    • Interactions between dopamine and oxytocin in the control of sexual behaviour
    • Baskerville T.A., Douglas A.J. Interactions between dopamine and oxytocin in the control of sexual behaviour. Prog. Brain Res. 2008, 170:277-290.
    • (2008) Prog. Brain Res. , vol.170 , pp. 277-290
    • Baskerville, T.A.1    Douglas, A.J.2
  • 7
    • 0015433570 scopus 로고
    • Innate and conditioned reactions to threat in rats with amygdaloid lesions
    • Blanchard D.C., Blanchard R.J. Innate and conditioned reactions to threat in rats with amygdaloid lesions. J. Comp. Physiol. Psychol. 1972, 81:281-290.
    • (1972) J. Comp. Physiol. Psychol. , vol.81 , pp. 281-290
    • Blanchard, D.C.1    Blanchard, R.J.2
  • 8
    • 0018134240 scopus 로고
    • Oxytocin, vasopressin and memory: opposite effects on consolidation and retrieval processes
    • Bohus B., Kovacs G.L., de Wied D. Oxytocin, vasopressin and memory: opposite effects on consolidation and retrieval processes. Brain Res. 1978, 157:414-417.
    • (1978) Brain Res. , vol.157 , pp. 414-417
    • Bohus, B.1    Kovacs, G.L.2    de Wied, D.3
  • 10
    • 33847662076 scopus 로고    scopus 로고
    • Consolidation of fear extinction requires NMDA receptor-dependent bursting in the ventromedial prefrontal cortex
    • Burgos-Robles A., Vidal-Gonzalez I., Santini E., Quirk G.J. Consolidation of fear extinction requires NMDA receptor-dependent bursting in the ventromedial prefrontal cortex. Neuron 2007, 53:871-880.
    • (2007) Neuron , vol.53 , pp. 871-880
    • Burgos-Robles, A.1    Vidal-Gonzalez, I.2    Santini, E.3    Quirk, G.J.4
  • 11
    • 37349008925 scopus 로고    scopus 로고
    • Attachment, aggression and affiliation: the role of oxytocin in female social behavior
    • Campbell A. Attachment, aggression and affiliation: the role of oxytocin in female social behavior. Biol. Psychol. 2008, 77:1-10.
    • (2008) Biol. Psychol. , vol.77 , pp. 1-10
    • Campbell, A.1
  • 12
    • 71549163431 scopus 로고    scopus 로고
    • Oxytocin decreases methamphetamine self-administration, methamphetamine hyperactivity, and relapse to methamphetamine-seeking behaviour in rats
    • Carson D.S., Cornish J.L., Guastella A.J., Hunt G.E., McGregor I.S. Oxytocin decreases methamphetamine self-administration, methamphetamine hyperactivity, and relapse to methamphetamine-seeking behaviour in rats. Neuropharmacology 2010, 58:38-43.
    • (2010) Neuropharmacology , vol.58 , pp. 38-43
    • Carson, D.S.1    Cornish, J.L.2    Guastella, A.J.3    Hunt, G.E.4    McGregor, I.S.5
  • 13
    • 0032815044 scopus 로고    scopus 로고
    • The intrinsic organization of the central extended amygdala
    • Cassell M.D., Freedman L.J., Shi C. The intrinsic organization of the central extended amygdala. Ann. N. Y. Acad. Sci. 1999, 877:217-241.
    • (1999) Ann. N. Y. Acad. Sci. , vol.877 , pp. 217-241
    • Cassell, M.D.1    Freedman, L.J.2    Shi, C.3
  • 15
    • 0032780713 scopus 로고    scopus 로고
    • The extended amygdala: are the central nucleus of the amygdala and the bed nucleus of the stria terminalis differentially involved in fear versus anxiety?
    • Davis M., Shi C. The extended amygdala: are the central nucleus of the amygdala and the bed nucleus of the stria terminalis differentially involved in fear versus anxiety?. Ann. N. Y. Acad. Sci. 1999, 877:281-291.
    • (1999) Ann. N. Y. Acad. Sci. , vol.877 , pp. 281-291
    • Davis, M.1    Shi, C.2
  • 16
    • 0025972983 scopus 로고
    • Interactive effects of neurohypophyseal neuropeptides with receptor antagonists on passive avoidance behavior: mediation by a cerebral neurohypophyseal hormone receptor?
    • de Wied D., Elands J., Kovacs G. Interactive effects of neurohypophyseal neuropeptides with receptor antagonists on passive avoidance behavior: mediation by a cerebral neurohypophyseal hormone receptor?. Proc. Natl. Acad. Sci. U. S. A. 1991, 88:1494-1498.
    • (1991) Proc. Natl. Acad. Sci. U. S. A. , vol.88 , pp. 1494-1498
    • de Wied, D.1    Elands, J.2    Kovacs, G.3
  • 17
    • 26244448127 scopus 로고    scopus 로고
    • Peptides of love and fear: vasopressin and oxytocin modulate the integration of information in the amygdala
    • Debiec J. Peptides of love and fear: vasopressin and oxytocin modulate the integration of information in the amygdala. Bioessays 2005, 27:869-873.
    • (2005) Bioessays , vol.27 , pp. 869-873
    • Debiec, J.1
  • 19
    • 0035887604 scopus 로고    scopus 로고
    • Oxytocin in the medial amygdala is essential for social recognition in the mouse
    • Ferguson J.N., Aldag J.M., Insel T.R., Young L.J. Oxytocin in the medial amygdala is essential for social recognition in the mouse. J. Neurosci. 2001, 21:8278-8285.
    • (2001) J. Neurosci. , vol.21 , pp. 8278-8285
    • Ferguson, J.N.1    Aldag, J.M.2    Insel, T.R.3    Young, L.J.4
  • 21
    • 26644446905 scopus 로고    scopus 로고
    • Prefrontal cortex in the rat: projections to subcortical autonomic, motor, and limbic centers
    • Gabbott P.L., Warner T.A., Jays P.R., Salway P., Busby S.J. Prefrontal cortex in the rat: projections to subcortical autonomic, motor, and limbic centers. J. Comp. Neurol. 2005, 492:145-177.
    • (2005) J. Comp. Neurol. , vol.492 , pp. 145-177
    • Gabbott, P.L.1    Warner, T.A.2    Jays, P.R.3    Salway, P.4    Busby, S.J.5
  • 22
    • 0035069755 scopus 로고    scopus 로고
    • The oxytocin receptor system: structure, function, and regulation
    • Gimpl G., Fahrenholz F. The oxytocin receptor system: structure, function, and regulation. Physiol. Rev. 2001, 81:629-683.
    • (2001) Physiol. Rev. , vol.81 , pp. 629-683
    • Gimpl, G.1    Fahrenholz, F.2
  • 23
    • 0142226952 scopus 로고    scopus 로고
    • Mapping oxytocin receptor gene expression in the mouse brain and mammary gland using an oxytocin receptor-LacZ reporter mouse
    • Gould B.R., Zingg H.H. Mapping oxytocin receptor gene expression in the mouse brain and mammary gland using an oxytocin receptor-LacZ reporter mouse. Neuroscience 2003, 122:155-167.
    • (2003) Neuroscience , vol.122 , pp. 155-167
    • Gould, B.R.1    Zingg, H.H.2
  • 24
    • 0034668879 scopus 로고    scopus 로고
    • Essential role of D1 but not D2 receptors in the NMDA receptor-dependent long-term potentiation at hippocampal-prefrontal cortex synapses in vivo
    • Gurden H., Takita M., Jay T.M. Essential role of D1 but not D2 receptors in the NMDA receptor-dependent long-term potentiation at hippocampal-prefrontal cortex synapses in vivo. J. Neurosci. 2000, 20:RC106.
    • (2000) J. Neurosci. , vol.20
    • Gurden, H.1    Takita, M.2    Jay, T.M.3
  • 26
    • 0037080322 scopus 로고    scopus 로고
    • Prefrontal cortex long-term potentiation, but not long-term depression, is associated with the maintenance of extinction of learned fear in mice
    • Herry C., Garcia R. Prefrontal cortex long-term potentiation, but not long-term depression, is associated with the maintenance of extinction of learned fear in mice. J. Neurosci. 2002, 22:577-583.
    • (2002) J. Neurosci. , vol.22 , pp. 577-583
    • Herry, C.1    Garcia, R.2
  • 27
    • 84862676715 scopus 로고    scopus 로고
    • The nonpeptide oxytocin receptor agonist WAY 267,464: receptor-binding profile, prosocial effects and distribution of c-Fos expression in adolescent rats
    • Hicks C., Jorgensen W., Brown C., Fardell J., Koehbach J., Gruber C.W., Kassiou M., Hunt G.E., McGregor I.S. The nonpeptide oxytocin receptor agonist WAY 267,464: receptor-binding profile, prosocial effects and distribution of c-Fos expression in adolescent rats. J. Neuroendocrinol. 2012, 24:1012-1029.
    • (2012) J. Neuroendocrinol. , vol.24 , pp. 1012-1029
    • Hicks, C.1    Jorgensen, W.2    Brown, C.3    Fardell, J.4    Koehbach, J.5    Gruber, C.W.6    Kassiou, M.7    Hunt, G.E.8    McGregor, I.S.9
  • 28
    • 44649115764 scopus 로고    scopus 로고
    • Microinfusion of the D1 receptor antagonist, SCH23390 into the IL but not the BLA impairs consolidation of extinction of auditory fear conditioning
    • Hikind N., Maroun M. Microinfusion of the D1 receptor antagonist, SCH23390 into the IL but not the BLA impairs consolidation of extinction of auditory fear conditioning. Neurobiol. Learn. Mem. 2008, 90:217-222.
    • (2008) Neurobiol. Learn. Mem. , vol.90 , pp. 217-222
    • Hikind, N.1    Maroun, M.2
  • 29
    • 16444367602 scopus 로고    scopus 로고
    • Vasopressin and oxytocin excite distinct neuronal populations in the central amygdala
    • Huber D., Veinante P., Stoop R. Vasopressin and oxytocin excite distinct neuronal populations in the central amygdala. Science 2005, 308:245-248.
    • (2005) Science , vol.308 , pp. 245-248
    • Huber, D.1    Veinante, P.2    Stoop, R.3
  • 30
    • 0026639650 scopus 로고
    • Oxytocin receptor distribution reflects social organization in monogamous and polygamous voles
    • Insel T.R., Shapiro L.E. Oxytocin receptor distribution reflects social organization in monogamous and polygamous voles. Proc. Natl. Acad. Sci. U. S. A. 1992, 89:5981-5985.
    • (1992) Proc. Natl. Acad. Sci. U. S. A. , vol.89 , pp. 5981-5985
    • Insel, T.R.1    Shapiro, L.E.2
  • 31
    • 3943064343 scopus 로고    scopus 로고
    • How the brain processes social information: searching for the social brain
    • Insel T.R., Fernald R.D. How the brain processes social information: searching for the social brain. Annu. Rev. Neurosci. 2004, 27:697-722.
    • (2004) Annu. Rev. Neurosci. , vol.27 , pp. 697-722
    • Insel, T.R.1    Fernald, R.D.2
  • 32
    • 0026652052 scopus 로고
    • Selective impairment of long-term but not short-term conditional fear by the N-methyl-d-aspartate antagonist APV
    • Kim J.J., Fanselow M.S., DeCola J.P., Landeira-Fernandez J. Selective impairment of long-term but not short-term conditional fear by the N-methyl-d-aspartate antagonist APV. Behav. Neurosci. 1992, 106:591-596.
    • (1992) Behav. Neurosci. , vol.106 , pp. 591-596
    • Kim, J.J.1    Fanselow, M.S.2    DeCola, J.P.3    Landeira-Fernandez, J.4
  • 33
    • 0027257425 scopus 로고
    • Electrolytic lesions of the amygdala block acquisition and expression of fear-potentiated startle even with extensive training but do not prevent reacquisition
    • Kim M., Davis M. Electrolytic lesions of the amygdala block acquisition and expression of fear-potentiated startle even with extensive training but do not prevent reacquisition. Behav. Neurosci. 1993, 107(4):580-595.
    • (1993) Behav. Neurosci. , vol.107 , Issue.4 , pp. 580-595
    • Kim, M.1    Davis, M.2
  • 34
    • 0022206473 scopus 로고
    • An increase in startle response in rats administered oxytocin
    • King M.G., Brown R., Kusnecov A. An increase in startle response in rats administered oxytocin. Peptides 1985, 6:567-568.
    • (1985) Peptides , vol.6 , pp. 567-568
    • King, M.G.1    Brown, R.2    Kusnecov, A.3
  • 37
    • 0018287028 scopus 로고
    • Effect of oxytocin and vasopressin on memory consolidation: sites of action and catecholaminergic correlates after local microinjection into limbic-midbrain structures
    • Kovacs G.L., Bohus B., Versteeg D.H., de Kloet E.R., de Wied D. Effect of oxytocin and vasopressin on memory consolidation: sites of action and catecholaminergic correlates after local microinjection into limbic-midbrain structures. Brain Res. 1979, 175:303-314.
    • (1979) Brain Res. , vol.175 , pp. 303-314
    • Kovacs, G.L.1    Bohus, B.2    Versteeg, D.H.3    de Kloet, E.R.4    de Wied, D.5
  • 38
    • 84875708607 scopus 로고    scopus 로고
    • Inhibition of the PI3 kinase cascade in corticolimbic circuit: temporal and differential effects on contextual fear and extinction
    • Kritman M., Maroun M. Inhibition of the PI3 kinase cascade in corticolimbic circuit: temporal and differential effects on contextual fear and extinction. Int. J. Neuropsychopharmacol. 2012, 16:825-833.
    • (2012) Int. J. Neuropsychopharmacol. , vol.16 , pp. 825-833
    • Kritman, M.1    Maroun, M.2
  • 39
    • 51649098192 scopus 로고    scopus 로고
    • Distinct contributions of the basolateral amygdala and the medial prefrontal cortex to learning and relearning extinction of context conditioned fear
    • Laurent V., Westbrook R.F. Distinct contributions of the basolateral amygdala and the medial prefrontal cortex to learning and relearning extinction of context conditioned fear. Learn. Mem. 2008, 15:657-666.
    • (2008) Learn. Mem. , vol.15 , pp. 657-666
    • Laurent, V.1    Westbrook, R.F.2
  • 40
    • 19544382872 scopus 로고    scopus 로고
    • Oxytocin receptors in brain cortical regions are reduced in haploinsufficient (+/-) reeler mice
    • Liu W., Pappas G.D., Carter C.S. Oxytocin receptors in brain cortical regions are reduced in haploinsufficient (+/-) reeler mice. Neurol. Res. 2005, 27:339-345.
    • (2005) Neurol. Res. , vol.27 , pp. 339-345
    • Liu, W.1    Pappas, G.D.2    Carter, C.S.3
  • 41
    • 84860602165 scopus 로고    scopus 로고
    • Enhanced extinction of aversive memories by high-frequency stimulation of the rat infralimbic cortex
    • Maroun M., Kavushansky A., Holmes A., Wellman C., Motanis H. Enhanced extinction of aversive memories by high-frequency stimulation of the rat infralimbic cortex. PLoS ONE 2012, 7:e35853.
    • (2012) PLoS ONE , vol.7
    • Maroun, M.1    Kavushansky, A.2    Holmes, A.3    Wellman, C.4    Motanis, H.5
  • 42
    • 0343113397 scopus 로고    scopus 로고
    • An anxiolytic action of oxytocin is enhanced by estrogen in the mouse
    • McCarthy M.M., McDonald C.H., Brooks P.J., Goldman D. An anxiolytic action of oxytocin is enhanced by estrogen in the mouse. Physiol. Behav. 1996, 60:1209-1215.
    • (1996) Physiol. Behav. , vol.60 , pp. 1209-1215
    • McCarthy, M.M.1    McDonald, C.H.2    Brooks, P.J.3    Goldman, D.4
  • 43
    • 0020416188 scopus 로고
    • Neurons of the lateral and basolateral amygdaloid nuclei: a Golgi study in the rat
    • McDonald A.J. Neurons of the lateral and basolateral amygdaloid nuclei: a Golgi study in the rat. J. Comp. Neurol. 1982, 212:293-312.
    • (1982) J. Comp. Neurol. , vol.212 , pp. 293-312
    • McDonald, A.J.1
  • 44
    • 78149470894 scopus 로고    scopus 로고
    • Oxytocin reduces background anxiety in a fear-potentiated startle paradigm
    • Missig G., Ayers L.W., Schulkin J., Rosen J.B. Oxytocin reduces background anxiety in a fear-potentiated startle paradigm. Neuropsychopharmacology 2010, 35:2607-2616.
    • (2010) Neuropsychopharmacology , vol.35 , pp. 2607-2616
    • Missig, G.1    Ayers, L.W.2    Schulkin, J.3    Rosen, J.B.4
  • 45
    • 77956406816 scopus 로고    scopus 로고
    • Exposure to a novel context following contextual fear conditioning enhances the induction of hippocampal long-term potentiation
    • Motanis H., Maroun M. Exposure to a novel context following contextual fear conditioning enhances the induction of hippocampal long-term potentiation. Eur. J. Neurosci. 2010, 32:840-846.
    • (2010) Eur. J. Neurosci. , vol.32 , pp. 840-846
    • Motanis, H.1    Maroun, M.2
  • 46
    • 36749070030 scopus 로고    scopus 로고
    • Stimuli and consequences of dendritic release of oxytocin within the brain
    • Neumann I.D. Stimuli and consequences of dendritic release of oxytocin within the brain. Biochem. Soc. Trans. 2007, 35:1252-1257.
    • (2007) Biochem. Soc. Trans. , vol.35 , pp. 1252-1257
    • Neumann, I.D.1
  • 47
    • 80053572989 scopus 로고    scopus 로고
    • Oxytocin suppresses basal glutamatergic transmission but facilitates activity-dependent synaptic potentiation in the medial prefrontal cortex
    • Ninan I. Oxytocin suppresses basal glutamatergic transmission but facilitates activity-dependent synaptic potentiation in the medial prefrontal cortex. J. Neurochem. 2011, 119:324-331.
    • (2011) J. Neurochem. , vol.119 , pp. 324-331
    • Ninan, I.1
  • 50
    • 0026486258 scopus 로고
    • Vasopressinergic modulation of stress responses in the central amygdala of the Roman high-avoidance and low-avoidance rat
    • Roozendaal B., Wiersma A., Driscoll P., Koolhaas J.M., Bohus B. Vasopressinergic modulation of stress responses in the central amygdala of the Roman high-avoidance and low-avoidance rat. Brain Res. 1992, 596:35-40.
    • (1992) Brain Res. , vol.596 , pp. 35-40
    • Roozendaal, B.1    Wiersma, A.2    Driscoll, P.3    Koolhaas, J.M.4    Bohus, B.5
  • 51
    • 43049156493 scopus 로고    scopus 로고
    • Fear conditioning and extinction differentially modify the intrinsic excitability of infralimbic neurons
    • Santini E., Quirk G.J., Porter J.T. Fear conditioning and extinction differentially modify the intrinsic excitability of infralimbic neurons. J. Neurosci. 2008, 28:4028-4036.
    • (2008) J. Neurosci. , vol.28 , pp. 4028-4036
    • Santini, E.1    Quirk, G.J.2    Porter, J.T.3
  • 53
    • 71549132494 scopus 로고    scopus 로고
    • Chronic icv oxytocin attenuates the pathological high anxiety state of selectively bred Wistar rats
    • Slattery D.A., Neumann I.D. Chronic icv oxytocin attenuates the pathological high anxiety state of selectively bred Wistar rats. Neuropharmacology 2010, 58:56-61.
    • (2010) Neuropharmacology , vol.58 , pp. 56-61
    • Slattery, D.A.1    Neumann, I.D.2
  • 54
    • 30344437919 scopus 로고    scopus 로고
    • Dopamine, oxytocin, and vasopressin receptor binding in the medial prefrontal cortex of monogamous and promiscuous voles
    • Smeltzer M.D., Curtis J.T., Aragona B.J., Wang Z. Dopamine, oxytocin, and vasopressin receptor binding in the medial prefrontal cortex of monogamous and promiscuous voles. Neurosci. Lett. 2006, 394:146-151.
    • (2006) Neurosci. Lett. , vol.394 , pp. 146-151
    • Smeltzer, M.D.1    Curtis, J.T.2    Aragona, B.J.3    Wang, Z.4
  • 55
    • 0026707275 scopus 로고
    • Oxytocin and vasopressin hexapeptide fragments have opposing influences on conditioned freezing behavior
    • Stoehr J.D., Cramer C.P., North W.G. Oxytocin and vasopressin hexapeptide fragments have opposing influences on conditioned freezing behavior. Psychoneuroendocrinology 1992, 17:267-271.
    • (1992) Psychoneuroendocrinology , vol.17 , pp. 267-271
    • Stoehr, J.D.1    Cramer, C.P.2    North, W.G.3
  • 56
    • 84866729264 scopus 로고    scopus 로고
    • Central administration of oxytocin receptor ligands affects cued fear extinction in rats and mice in a timepoint-dependent manner
    • Toth I., Neumann I.D., Slattery D.A. Central administration of oxytocin receptor ligands affects cued fear extinction in rats and mice in a timepoint-dependent manner. Psychopharmacology (Berl.) 2012, 223:149-158.
    • (2012) Psychopharmacology (Berl.) , vol.223 , pp. 149-158
    • Toth, I.1    Neumann, I.D.2    Slattery, D.A.3
  • 57
    • 0026759715 scopus 로고
    • Oxytocin reduces exploratory motor behaviour and shifts the activity towards the centre of the arena in male rats
    • Uvnäs-Moberg K., Alster P., Hillegaart V., Ahlenius S. Oxytocin reduces exploratory motor behaviour and shifts the activity towards the centre of the arena in male rats. Acta Physiol. Scand. 1992, 145:429-430.
    • (1992) Acta Physiol. Scand. , vol.145 , pp. 429-430
    • Uvnäs-Moberg, K.1    Alster, P.2    Hillegaart, V.3    Ahlenius, S.4
  • 58
    • 0028169479 scopus 로고
    • High doses of oxytocin cause sedation and low doses cause an anxiolytic-like effect in male rats
    • Uvnäs-Moberg K., Ahlenius S., Hillegaart V., Alster P. High doses of oxytocin cause sedation and low doses cause an anxiolytic-like effect in male rats. Pharmacol. Biochem. Behav. 1994, 49:101-106.
    • (1994) Pharmacol. Biochem. Behav. , vol.49 , pp. 101-106
    • Uvnäs-Moberg, K.1    Ahlenius, S.2    Hillegaart, V.3    Alster, P.4
  • 59
    • 0031298154 scopus 로고    scopus 로고
    • Oxytocin linked antistress effects - the relaxation and growth response
    • Uvnas-Moberg K. Oxytocin linked antistress effects - the relaxation and growth response. Acta Physiol. Scand. Suppl. 1997, 640:38-42.
    • (1997) Acta Physiol. Scand. Suppl. , vol.640 , pp. 38-42
    • Uvnas-Moberg, K.1
  • 60
    • 0345059241 scopus 로고    scopus 로고
    • Oxytocin may mediate the benefits of positive social interaction and emotions
    • Uvnas-Moberg K. Oxytocin may mediate the benefits of positive social interaction and emotions. Psychoneuroendocrinology 1998, 23:819-835.
    • (1998) Psychoneuroendocrinology , vol.23 , pp. 819-835
    • Uvnas-Moberg, K.1
  • 61
    • 0030988453 scopus 로고    scopus 로고
    • Distribution of oxytocin- and vasopressin-binding sites in the rat extended amygdala: a histoautoradiographic study
    • Veinante P., Freund-Mercier M.J. Distribution of oxytocin- and vasopressin-binding sites in the rat extended amygdala: a histoautoradiographic study. J. Comp. Neurol. 1997, 383:305-325.
    • (1997) J. Comp. Neurol. , vol.383 , pp. 305-325
    • Veinante, P.1    Freund-Mercier, M.J.2
  • 62
    • 33748471314 scopus 로고    scopus 로고
    • Microstimulation reveals opposing influences of prelimbic and infralimbic cortex on the expression of conditioned fear
    • Vidal-Gonzalez I., Vidal-Gonzalez B., Rauch S.L., Quirk G.J. Microstimulation reveals opposing influences of prelimbic and infralimbic cortex on the expression of conditioned fear. Learn. Mem. 2006, 13(6):728-733.
    • (2006) Learn. Mem. , vol.13 , Issue.6 , pp. 728-733
    • Vidal-Gonzalez, I.1    Vidal-Gonzalez, B.2    Rauch, S.L.3    Quirk, G.J.4
  • 64
    • 80052754085 scopus 로고    scopus 로고
    • Learning-induced changes in mPFC-BLA connections after fear conditioning, extinction, and reinstatement of fear
    • Vouimba R.M., Maroun M. Learning-induced changes in mPFC-BLA connections after fear conditioning, extinction, and reinstatement of fear. Neuropsychopharmacology 2011, 36:2276-2285.
    • (2011) Neuropsychopharmacology , vol.36 , pp. 2276-2285
    • Vouimba, R.M.1    Maroun, M.2
  • 65
    • 5444251690 scopus 로고    scopus 로고
    • Neurochemical regulation of pair bonding in male prairie voles
    • Wang Z., Aragona B.J. Neurochemical regulation of pair bonding in male prairie voles. Physiol. Behav. 2004, 83:319-328.
    • (2004) Physiol. Behav. , vol.83 , pp. 319-328
    • Wang, Z.1    Aragona, B.J.2
  • 66
    • 2142705710 scopus 로고    scopus 로고
    • Neonatal manipulations of oxytocin alter expression of oxytocin and vasopressin immunoreactive cells in the paraventricular nucleus of the hypothalamus in a gender-specific manner
    • Yamamoto Y., Cushing B.S., Kramer K.M., Epperson P.D., Hoffman G.E., Carter C.S. Neonatal manipulations of oxytocin alter expression of oxytocin and vasopressin immunoreactive cells in the paraventricular nucleus of the hypothalamus in a gender-specific manner. Neuroscience 2004, 125:947-955.
    • (2004) Neuroscience , vol.125 , pp. 947-955
    • Yamamoto, Y.1    Cushing, B.S.2    Kramer, K.M.3    Epperson, P.D.4    Hoffman, G.E.5    Carter, C.S.6
  • 67
    • 34548831959 scopus 로고    scopus 로고
    • The central nucleus of the amygdala is essential for acquiring and expressing conditional fear after overtraining
    • Zimmerman J.M., Rabinak C.A., McLachlan I.G., Maren S. The central nucleus of the amygdala is essential for acquiring and expressing conditional fear after overtraining. Learn. Mem. 2007, 14:634-644.
    • (2007) Learn. Mem. , vol.14 , pp. 634-644
    • Zimmerman, J.M.1    Rabinak, C.A.2    McLachlan, I.G.3    Maren, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.