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Volumn 24, Issue 7, 2013, Pages 1762-1769

Evaluation of short-course radiotherapy followed by neoadjuvant bevacizumab, capecitabine, and oxaliplatin and subsequent radical surgical treatment in primary stage IV rectal cancer

Author keywords

Bevacizumab; Neoadjuvant chemotherapy; Preoperative radiotherapy; Rectal cancer; Stage IV

Indexed keywords

BEVACIZUMAB; CAPECITABINE; OXALIPLATIN;

EID: 84883802248     PISSN: 09237534     EISSN: 15698041     Source Type: Journal    
DOI: 10.1093/annonc/mdt124     Document Type: Article
Times cited : (108)

References (46)
  • 1
    • 68549125707 scopus 로고    scopus 로고
    • Preoperative chemoradiation versus radiation alone for stage II and III resectable rectal cancer
    • Ceelen WP, Van Nieuwenhove Y, Fierens K. Preoperative chemoradiation versus radiation alone for stage II and III resectable rectal cancer. Cochrane Database Syst Rev 2009; 1: CD006041.
    • (2009) Cochrane Database Syst Rev , vol.1
    • Ceelen, W.P.1    Van Nieuwenhove, Y.2    Fierens, K.3
  • 2
    • 33750580102 scopus 로고    scopus 로고
    • Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203
    • Gerard JP, Conroy T, Bonnetain F et al. Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203. J Clin Oncol 2006; 24: 4620-4625.
    • (2006) J Clin Oncol , vol.24 , pp. 4620-4625
    • Gerard, J.P.1    Conroy, T.2    Bonnetain, F.3
  • 3
    • 34247848005 scopus 로고    scopus 로고
    • Bevacizumab, oxaliplatin, and capecitabine with radiation therapy in rectal cancer: phase I trial results
    • Czito BG, Bendell JC, Willett CG et al. Bevacizumab, oxaliplatin, and capecitabine with radiation therapy in rectal cancer: phase I trial results. Int J Radiat Oncol Biol Phys 2007; 68: 472-478.
    • (2007) Int J Radiat Oncol Biol Phys , vol.68 , pp. 472-478
    • Czito, B.G.1    Bendell, J.C.2    Willett, C.G.3
  • 4
    • 79957976658 scopus 로고    scopus 로고
    • Beyond 5-fluorouracil: the emerging role of newer chemotherapeutics and targeted agents with radiation therapy
    • Czito BG, Willett CG. Beyond 5-fluorouracil: the emerging role of newer chemotherapeutics and targeted agents with radiation therapy. Semin Radiat Oncol 2011; 21: 203-211.
    • (2011) Semin Radiat Oncol , vol.21 , pp. 203-211
    • Czito, B.G.1    Willett, C.G.2
  • 6
    • 34247847960 scopus 로고    scopus 로고
    • Complete pathological response to bevacizumab and chemoradiation in advanced rectal cancer
    • Willett CG, Duda DG, di Tomaso E et al. Complete pathological response to bevacizumab and chemoradiation in advanced rectal cancer. Nat Clin Pract Oncol 2007; 4: 316-321.
    • (2007) Nat Clin Pract Oncol , vol.4 , pp. 316-321
    • Willett, C.G.1    Duda, D.G.2    Di Tomaso, E.3
  • 7
    • 83955163008 scopus 로고    scopus 로고
    • Neoadjuvant bevacizumab, oxaliplatin, 5-fluorouracil, and radiation for rectal cancer
    • Dipetrillo T, Pricolo V, Lagares-Garcia J et al. Neoadjuvant bevacizumab, oxaliplatin, 5-fluorouracil, and radiation for rectal cancer. Int J Radiat Oncol Biol Phys 2012; 82: 124-129.
    • (2012) Int J Radiat Oncol Biol Phys , vol.82 , pp. 124-129
    • Dipetrillo, T.1    Pricolo, V.2    Lagares-Garcia, J.3
  • 8
    • 84455191894 scopus 로고    scopus 로고
    • Preoperative treatment with capecitabine, bevacizumab and radiotherapy for primary locally advanced rectal cancer-a two stage phase II clinical trial
    • Resch G, De Vries A, Öfner D et al. Preoperative treatment with capecitabine, bevacizumab and radiotherapy for primary locally advanced rectal cancer-a two stage phase II clinical trial. Radiother Oncol 2012; 102: 10-13.
    • (2012) Radiother Oncol , vol.102 , pp. 10-13
    • Resch, G.1    De Vries, A.2    Öfner, D.3
  • 9
    • 84874560532 scopus 로고    scopus 로고
    • Neoadjuvant chemoradiotherapy with or without panitumumab in patients with wild-type KRAS, locally advanced rectal cancer (LARC): a randomized, multicenter, phase II trial SAKK 41/07
    • Helbling D, Bodoky G, Gautschi O et al. Neoadjuvant chemoradiotherapy with or without panitumumab in patients with wild-type KRAS, locally advanced rectal cancer (LARC): a randomized, multicenter, phase II trial SAKK 41/07. Ann Oncol 2012; 3: 718-725.
    • (2012) Ann Oncol , vol.3 , pp. 718-725
    • Helbling, D.1    Bodoky, G.2    Gautschi, O.3
  • 10
    • 64049090266 scopus 로고    scopus 로고
    • The 'liver-first approach' for patients with locally advanced rectal cancer and synchronous liver metastases
    • Verhoef C, van der Pool AE, Nuyttens JJ et al. The 'liver-first approach' for patients with locally advanced rectal cancer and synchronous liver metastases. Dis Colon Rectum 2009; 52: 23-30.
    • (2009) Dis Colon Rectum , vol.52 , pp. 23-30
    • Verhoef, C.1    Van der Pool, A.E.2    Nuyttens, J.J.3
  • 11
    • 0141525385 scopus 로고    scopus 로고
    • A systematic overview of radiation therapy effects in rectal cancer
    • Glimelius B, GrÖnberg H, Järhult J et al. A systematic overview of radiation therapy effects in rectal cancer. Acta Oncol 2003; 42: 476-492.
    • (2003) Acta Oncol , vol.42 , pp. 476-492
    • Glimelius, B.1    Grönberg, H.2    Järhult, J.3
  • 12
    • 3242716904 scopus 로고    scopus 로고
    • Sphincter preservation following preoperative radiotherapy for rectal cancer: report of a randomised trial comparing short-term radiotherapy vs. conventionally fractionated radiochemotherapy
    • Bujko K, Nowacki MP, Nasierowska-Guttmejer A et al. Sphincter preservation following preoperative radiotherapy for rectal cancer: report of a randomised trial comparing short-term radiotherapy vs. conventionally fractionated radiochemotherapy. Radiother Oncol 2004; 72: 15-24.
    • (2004) Radiother Oncol , vol.72 , pp. 15-24
    • Bujko, K.1    Nowacki, M.P.2    Nasierowska-Guttmejer, A.3
  • 13
    • 0034594628 scopus 로고    scopus 로고
    • New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada
    • Therasse P, Arbuck SG, Eisenhauer EA et al. New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst 2000; 92: 205-216.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 205-216
    • Therasse, P.1    Arbuck, S.G.2    Eisenhauer, E.A.3
  • 14
    • 0022466378 scopus 로고
    • Local recurrence of rectal adenocarcinoma due to inadequate surgical resection. Histopathological study of lateral tumour spread and surgical excision
    • Quirke P, Durdey P, Dixon MF et al. Local recurrence of rectal adenocarcinoma due to inadequate surgical resection. Histopathological study of lateral tumour spread and surgical excision. Lancet 1986; 2: 996-999.
    • (1986) Lancet , vol.2 , pp. 996-999
    • Quirke, P.1    Durdey, P.2    Dixon, M.F.3
  • 15
    • 0028305674 scopus 로고
    • Pathologic assessment of tumor regression after preoperative chemoradiotherapy of esophageal carcinoma
    • Mandard AM, Dalibard F, Mandard JC et al. Pathologic assessment of tumor regression after preoperative chemoradiotherapy of esophageal carcinoma. Clinicopathologic correlations. Cancer 1994; 73: 2680-2686.
    • (1994) Clinicopathologic correlations. Cancer , vol.73 , pp. 2680-2686
    • Mandard, A.M.1    Dalibard, F.2    Mandard, J.C.3
  • 16
    • 0036533877 scopus 로고    scopus 로고
    • Macroscopic evaluation of rectal cancer resection specimen: clinical significance of the pathologist in quality control
    • Nagtegaal ID, van de Velde CJ, van der Worp E et al. Macroscopic evaluation of rectal cancer resection specimen: clinical significance of the pathologist in quality control. J Clin Oncol 2002; 20: 1729-1734.
    • (2002) J Clin Oncol , vol.20 , pp. 1729-1734
    • Nagtegaal, I.D.1    Van de Velde, C.J.2    Van der Worp, E.3
  • 17
    • 84859159725 scopus 로고    scopus 로고
    • Increase in volume of ablation zones during follow-up is highly suggestive of ablation site recurrence in colorectal liver metastases treated with radiofrequency ablation
    • Kele PG, de Jong KP, van der Jagt EJ. Increase in volume of ablation zones during follow-up is highly suggestive of ablation site recurrence in colorectal liver metastases treated with radiofrequency ablation. J Vasc Interv Radiol 2012; 23: 537-544.
    • (2012) J Vasc Interv Radiol , vol.23 , pp. 537-544
    • Kele, P.G.1    De Jong, K.P.2    van der Jagt, E.J.3
  • 19
    • 0035018397 scopus 로고    scopus 로고
    • Five-year survival following hepatic resection after neoadjuvant therapy for nonresectable colorectal
    • Adam R, Avisar E, Ariche A et al. Five-year survival following hepatic resection after neoadjuvant therapy for nonresectable colorectal. Ann Surg Oncol 2001; 8: 347-353.
    • (2001) Ann Surg Oncol , vol.8 , pp. 347-353
    • Adam, R.1    Avisar, E.2    Ariche, A.3
  • 20
    • 23844448040 scopus 로고    scopus 로고
    • Neoadjuvant treatment of unresectable colorectal liver metastases: correlation between tumour response and resection rates
    • Folprecht G, Grothey A, Alberts S et al. Neoadjuvant treatment of unresectable colorectal liver metastases: correlation between tumour response and resection rates. Ann Oncol 2005; 16: 1311-1319.
    • (2005) Ann Oncol , vol.16 , pp. 1311-1319
    • Folprecht, G.1    Grothey, A.2    Alberts, S.3
  • 21
    • 34548476513 scopus 로고    scopus 로고
    • Does chemotherapy prior to liver resection increase the potential for cure in patients with metastatic colorectal cancer? A report from the European Colorectal Metastases Treatment Group
    • Nordlinger B, Van Cutsem E, Rougier P et al. Does chemotherapy prior to liver resection increase the potential for cure in patients with metastatic colorectal cancer? A report from the European Colorectal Metastases Treatment Group. Eur J Cancer 2007; 43: 2037-2045.
    • (2007) Eur J Cancer , vol.43 , pp. 2037-2045
    • Nordlinger, B.1    Van Cutsem, E.2    Rougier, P.3
  • 22
    • 70349690209 scopus 로고    scopus 로고
    • Surgery with curative-intent in patients treated with first-line chemotherapy plus bevacizumab for metastatic colorectal cancer First BEAT and the randomised phase-III NO16966 trial
    • Okines A, Puerto OD, Cunningham D et al. Surgery with curative-intent in patients treated with first-line chemotherapy plus bevacizumab for metastatic colorectal cancer First BEAT and the randomised phase-III NO16966 trial. Br J Cancer 2009; 101: 1033-1038.
    • (2009) Br J Cancer , vol.101 , pp. 1033-1038
    • Okines, A.1    Puerto, O.D.2    Cunningham, D.3
  • 23
    • 24944499364 scopus 로고    scopus 로고
    • Enhanced tumorocidal effect of chemotherapy with preoperative radiotherapy for rectal cancer: preliminary results-EORTC 22921
    • Bosset JF, Calais G, Mineur L et al. Enhanced tumorocidal effect of chemotherapy with preoperative radiotherapy for rectal cancer: preliminary results-EORTC 22921. J Clin Oncol 2005; 23: 5620-5627.
    • (2005) J Clin Oncol , vol.23 , pp. 5620-5627
    • Bosset, J.F.1    Calais, G.2    Mineur, L.3
  • 24
    • 79956219437 scopus 로고    scopus 로고
    • Pathologic complete response after neoadjuvant treatment for rectal cancer decreases distant recurrence and could eradicate local recurrence
    • de Campos-Lobato LF, Stocchi L, da Luz Moreira A et al. Pathologic complete response after neoadjuvant treatment for rectal cancer decreases distant recurrence and could eradicate local recurrence. Ann Surg Oncol 2011; 18: 1590-1598.
    • (2011) Ann Surg Oncol , vol.18 , pp. 1590-1598
    • De Campos-Lobato, L.F.1    Stocchi, L.2    Da Luz Moreira, A.3
  • 25
    • 79959511682 scopus 로고    scopus 로고
    • Optimal timing of surgery after chemoradiation for advanced rectal cancer: preliminary results of a multicenter, nonrandomized phase II prospective trial
    • Garcia-Aguilar J, Smith DD, Avila K et al. Optimal timing of surgery after chemoradiation for advanced rectal cancer: preliminary results of a multicenter, nonrandomized phase II prospective trial. Ann Surg 2011; 254: 97-102.
    • (2011) Ann Surg , vol.254 , pp. 97-102
    • Garcia-Aguilar, J.1    Smith, D.D.2    Avila, K.3
  • 26
    • 77956185901 scopus 로고    scopus 로고
    • Long-term outcome in patients with a pathological complete response after chemoradiation for rectal cancer: a pooled analysis of individual patient data
    • Maas M, Nelemans PJ, Valentini V et al. Long-term outcome in patients with a pathological complete response after chemoradiation for rectal cancer: a pooled analysis of individual patient data. Lancet Oncol 2010; 11: 835-844.
    • (2010) Lancet Oncol , vol.11 , pp. 835-844
    • Maas, M.1    Nelemans, P.J.2    Valentini, V.3
  • 27
    • 84862775402 scopus 로고    scopus 로고
    • Systematic review and meta-analysis of outcomes following pathological complete response to neoadjuvant chemoradiotherapy for rectal cancer
    • Martin ST, Heneghan HM, Winter DC. Systematic review and meta-analysis of outcomes following pathological complete response to neoadjuvant chemoradiotherapy for rectal cancer. Br J Surg 2012; 99: 918-928.
    • (2012) Br J Surg , vol.99 , pp. 918-928
    • Martin, S.T.1    Heneghan, H.M.2    Winter, D.C.3
  • 28
    • 77955244529 scopus 로고    scopus 로고
    • Tumor volume reduction rate measured by magnetic resonance volumetry correlated with pathologic tumor response of preoperative chemoradiotherapy for rectal cancer
    • Yeo SG, Kim DY, Kim TH et al. Tumor volume reduction rate measured by magnetic resonance volumetry correlated with pathologic tumor response of preoperative chemoradiotherapy for rectal cancer. Int J Radiat Oncol Biol Phys 2010; 78: 164-171.
    • (2010) Int J Radiat Oncol Biol Phys , vol.78 , pp. 164-171
    • Yeo, S.G.1    Kim, D.Y.2    Kim, T.H.3
  • 29
    • 39549106051 scopus 로고    scopus 로고
    • Preoperative chemoradiation with capecitabine in locally advanced rectal cancer
    • de Bruin AF, Nuyttens JJ, Ferenschild FT et al. Preoperative chemoradiation with capecitabine in locally advanced rectal cancer. Neth J Med 2008; 66: 71-76.
    • (2008) Neth J Med , vol.66 , pp. 71-76
    • De Bruin, A.F.1    Nuyttens, J.J.2    Ferenschild, F.T.3
  • 30
    • 45049086609 scopus 로고    scopus 로고
    • Short-course preoperative radiotherapy with delayed surgery in rectal cancer-a retrospective study
    • Radu C, Berglund A, Påhlman L et al. Short-course preoperative radiotherapy with delayed surgery in rectal cancer-a retrospective study. Radiother Oncol 2008; 87: 343-349.
    • (2008) Radiother Oncol , vol.87 , pp. 343-349
    • Radu, C.1    Berglund, A.2    Påhlman, L.3
  • 31
    • 0030951055 scopus 로고    scopus 로고
    • Short-term preoperative radiotherapy results in down-staging of rectal cancer: a study of 1316 patients
    • Graf W, Dahlberg M, Osman MM et al. Short-term preoperative radiotherapy results in down-staging of rectal cancer: a study of 1316 patients. Radiother Oncol 1997; 43: 133-137.
    • (1997) Radiother Oncol , vol.43 , pp. 133-137
    • Graf, W.1    Dahlberg, M.2    Osman, M.M.3
  • 32
    • 67650979463 scopus 로고    scopus 로고
    • Short-course radiotherapy, with elective delay prior to surgery, in patients with unresectable rectal cancer who have poor performance status or significant co-morbidity
    • Hatfield P, Hingorani M, Radhakrishna G et al. Short-course radiotherapy, with elective delay prior to surgery, in patients with unresectable rectal cancer who have poor performance status or significant co-morbidity. Radiother Oncol 2009; 92: 210-214.
    • (2009) Radiother Oncol , vol.92 , pp. 210-214
    • Hatfield, P.1    Hingorani, M.2    Radhakrishna, G.3
  • 33
    • 84858076738 scopus 로고    scopus 로고
    • Preoperative short-course radiotherapy with delayed surgery in primary rectal cancer
    • Pettersson D, Holm T, Iversen H et al. Preoperative short-course radiotherapy with delayed surgery in primary rectal cancer. Br J Surg 2012; 99: 577-583.
    • (2012) Br J Surg , vol.99 , pp. 577-583
    • Pettersson, D.1    Holm, T.2    Iversen, H.3
  • 34
    • 75749100265 scopus 로고    scopus 로고
    • American Society of Clinical Oncology 2009 clinical evidence review on radiofrequency ablation of hepatic metastases from colorectal cancer
    • Wong SL, Mangu PB, Choti MA et al. American Society of Clinical Oncology 2009 clinical evidence review on radiofrequency ablation of hepatic metastases from colorectal cancer. J Clin Oncol 2010; 28: 493-508.
    • (2010) J Clin Oncol , vol.28 , pp. 493-508
    • Wong, S.L.1    Mangu, P.B.2    Choti, M.A.3
  • 35
    • 38049138477 scopus 로고    scopus 로고
    • Radiofrequency ablation versus resection for resectable colorectal liver metastases: time for a randomized trial?
    • Mulier S, Ni Y, Jamart J et al. Radiofrequency ablation versus resection for resectable colorectal liver metastases: time for a randomized trial? Ann Surg Oncol 2008; 15: 144-157.
    • (2008) Ann Surg Oncol , vol.15 , pp. 144-157
    • Mulier, S.1    Ni, Y.2    Jamart, J.3
  • 36
    • 3242744598 scopus 로고    scopus 로고
    • Local recurrences after intraoperative radiofrequency ablation of liver metastases: a comparative study with anatomic and wedge resections
    • Elias D, Baton O, Sideris L et al. Local recurrences after intraoperative radiofrequency ablation of liver metastases: a comparative study with anatomic and wedge resections. Ann Surg Oncol 2004; 11: 500-505.
    • (2004) Ann Surg Oncol , vol.11 , pp. 500-505
    • Elias, D.1    Baton, O.2    Sideris, L.3
  • 37
    • 41549167668 scopus 로고    scopus 로고
    • A randomised phase III study on capecitabine, oxaliplatin and bevacizumab with or without cetuximab in first-line advanced colorectal cancer, the CAIRO2 study of the Dutch Colorectal Cancer Group (DCCG)
    • Tol J, Koopman M, Rodenburg CJ et al. A randomised phase III study on capecitabine, oxaliplatin and bevacizumab with or without cetuximab in first-line advanced colorectal cancer, the CAIRO2 study of the Dutch Colorectal Cancer Group (DCCG). An interim analysis of toxicity. Ann Oncol 2008; 19: 734-738.
    • (2008) An interim analysis of toxicity. Ann Oncol , vol.19 , pp. 734-738
    • Tol, J.1    Koopman, M.2    Rodenburg, C.J.3
  • 38
    • 67649921334 scopus 로고    scopus 로고
    • Efficacy, safety, and biomarkers of neoadjuvant bevacizumab, radiation therapy, and fluorouracil in rectal cancer: a multidisciplinary phase II study
    • Willett CG, Duda DG, di Tomaso E et al. Efficacy, safety, and biomarkers of neoadjuvant bevacizumab, radiation therapy, and fluorouracil in rectal cancer: a multidisciplinary phase II study. J Clin Oncol 2009; 27: 3020-3026.
    • (2009) J Clin Oncol , vol.27 , pp. 3020-3026
    • Willett, C.G.1    Duda, D.G.2    Di Tomaso, E.3
  • 39
    • 76049088643 scopus 로고    scopus 로고
    • Phase II trial of neoadjuvant bevacizumab, capecitabine, and radiotherapy for locally advanced rectal cancer
    • Crane CH, Eng C, Feig BW et al. Phase II trial of neoadjuvant bevacizumab, capecitabine, and radiotherapy for locally advanced rectal cancer. Int J Radiat Oncol Biol Phys 2010; 76: 824-830.
    • (2010) Int J Radiat Oncol Biol Phys , vol.76 , pp. 824-830
    • Crane, C.H.1    Eng, C.2    Feig, B.W.3
  • 40
    • 24344442899 scopus 로고    scopus 로고
    • Surgical wound healing complications in metastatic colorectal cancer patients treated with bevacizumab
    • Scappaticci FA, Fehrenbacher L, Cartwright T et al. Surgical wound healing complications in metastatic colorectal cancer patients treated with bevacizumab. J Surg Oncol 2005; 91: 173-180.
    • (2005) J Surg Oncol , vol.91 , pp. 173-180
    • Scappaticci, F.A.1    Fehrenbacher, L.2    Cartwright, T.3
  • 41
    • 33745843646 scopus 로고    scopus 로고
    • Neoadjuvant chemotherapy and resection of advanced synchronous liver metastases before treatment of the colorectal primary
    • Mentha G, Majno PE, Andres A et al. Neoadjuvant chemotherapy and resection of advanced synchronous liver metastases before treatment of the colorectal primary. Br J Surg 2006; 93: 872-878.
    • (2006) Br J Surg , vol.93 , pp. 872-878
    • Mentha, G.1    Majno, P.E.2    Andres, A.3
  • 42
    • 76649132989 scopus 로고    scopus 로고
    • Optimizing the outcome of surgery in patients with rectal cancer and synchronous liver metastases
    • Van der Pool AE, de Wilt JH, Lalmahomed ZS et al. Optimizing the outcome of surgery in patients with rectal cancer and synchronous liver metastases. Br J Surg 2010; 97: 383-390.
    • (2010) Br J Surg , vol.97 , pp. 383-390
    • Van der Pool, A.E.1    De Wilt, J.H.2    Lalmahomed, Z.S.3
  • 43
    • 84867846221 scopus 로고    scopus 로고
    • Patterns of failure in patients with early onset (synchronous) resectable liver metastases from rectal cancer
    • Butte JM, Gonen M, Ding P et al. Patterns of failure in patients with early onset (synchronous) resectable liver metastases from rectal cancer. Cancer 2012; 1: 5414-5423.
    • (2012) Cancer , vol.1 , pp. 5414-5423
    • Butte, J.M.1    Gonen, M.2    Ding, P.3
  • 44
    • 34548656472 scopus 로고    scopus 로고
    • Predictors of early disease recurrence following hepatic resection for colorectal cancer metastasis
    • Malik HZ, Gomez D, Wong V et al. Predictors of early disease recurrence following hepatic resection for colorectal cancer metastasis. Eur J Surg Oncol 2007; 33: 1003-1009.
    • (2007) Eur J Surg Oncol , vol.33 , pp. 1003-1009
    • Malik, H.Z.1    Gomez, D.2    Wong, V.3
  • 45
    • 79956190032 scopus 로고    scopus 로고
    • Risk factors for early recurrence after curative hepatectomy for colorectal liver metastases
    • Yamashita Y, Adachi E, Toh Y et al. Risk factors for early recurrence after curative hepatectomy for colorectal liver metastases. Surg Today 2011; 41: 526-532.
    • (2011) Surg Today , vol.41 , pp. 526-532
    • Yamashita, Y.1    Adachi, E.2    Toh, Y.3
  • 46
    • 73249130298 scopus 로고    scopus 로고
    • Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: the CELIM randomised phase 2 trial
    • Folprecht G, Gruenberger T, Bechstein WO et al. Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: the CELIM randomised phase 2 trial. Lancet Oncol 2010; 11: 38-47.
    • (2010) Lancet Oncol , vol.11 , pp. 38-47
    • Folprecht, G.1    Gruenberger, T.2    Bechstein, W.O.3


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