Preoperative chemoradiation versus radiation alone for stage II and III resectable rectal cancer

Cochrane Database of Systematic Reviews

Volumn , Issue 1, 2009, Pages

  Ceelen, Wim P ^a   Van Nieuwenhove, Yves ^b   Fierens, Kjell ^a  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

^b FREE UNIVERSITY OF BRUSSELS   (Belgium)

Author keywords

*Neoplasm recurrence; Humans; Local prevention control ; Randomized controlled trials as topic; Rectal neoplasms *drug therapy; pathology; *radiotherapy; surgery

Indexed keywords

FLUOROURACIL; FOLINIC ACID;

ANUS SPHINCTER; CANCER CHEMOTHERAPY; CANCER COMBINATION CHEMOTHERAPY; CANCER MORTALITY; CANCER PATIENT; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER STAGING; CANCER SURGERY; CLINICAL TRIAL; DISEASE FREE SURVIVAL; EXTERNAL BEAM RADIOTHERAPY; HUMAN; META ANALYSIS; METASTASIS; MORBIDITY; MULTIPLE CYCLE TREATMENT; OVERALL SURVIVAL; PREOPERATIVE CARE; PROGNOSIS; RADIATION INJURY; RECTUM CANCER; REVIEW; SYSTEMATIC REVIEW; UNSPECIFIED SIDE EFFECT;

EID: 68549125707     PISSN: 1469493X     EISSN: None     Source Type: Journal    
DOI: 10.1002/14651858.CD006041.pub2     Document Type: Review

References (34)

1. Bosset JF, Collette L, Calais G, Mineur L, Maingon P, Radosevic-Jelic L, Daban A, Bardet E, Beny A, Ollier JC, EORTC Radiotherapy Group Trial 22921. Chemotherapy with Preoperative Radiotherapy in Rectal Cancer. The New England Journal of Medicine 2006;355:1114-1123
2. S. Boulis-Wassif, A. Gerard, J. Loygue, D. Camelot, M. Buyse, N. Duez. Final Results of a Randomized Trial on the Treatment of Rectal Cancer with Preoperative Radiotherapy Alone or in Combination With 5-Fluorouracil, Followed by radical surgery. Cancer 1984;53:1811-1818.
3. Bujko K, Nowacki MP, Nasierowska-Guttmejer A, Michalski W, Bebenek M, Kryj M. Long-term results of a randomized trial comparing preoperative short-course radiotherapy with preoperative conventionally fractionated chemoradiation for rectal cancer. British Journal of Surgery 2006;93:1215-1223. (Pubitemid 44547018)
4. Jean-Pierre Gérard, Thierry Conroy, Franck Bonnetain, Olivier Bouché, Olivier Chapet, Marie-Thérèse Closon-Dejardin, Michel Untereiner, Bernard Leduc, Eric Francois, Jean Maurel, Jean-Francois Seitz, Bruno Buecher, Rémy Mackiewicz, Michel Ducreux, Laurent Bedenne. Preoperative Radiotherapy With or Without Concurrent Fluorouracil and Leucovorin in T3-T4 Rectal Cancers: Results of FFCD 9203. J Clin Oncol 2006;24:4620-4625.
5. Ammann K, Kirchmayr W, Klaus A, Muhlmann G, Kafka R, Oberwalder M, De Vries A, Ofner D, Weiss H. Impact of neoadjuvant chemoradiation on anal sphincter function in patients with carcinoma of the midrectum and low rectum. Archives of Surgery 2003;138(3):257-261. (Pubitemid 36292658)
6. Beets-Tan RGH, Beets GL. Rectal cancer: how accurate can imaging predict the T stage and the circumferential resection margin?. International Journal of Colorectal Disease 2003;18(5):385-391.
7. Beets-Tan RGH, Lettinga T, Beets GL. Pre-operative imaging of rectal cancer and its impact on surgical performance and treatment outcome. Ejso 2005;31(6):681-688. (Pubitemid 40975251)
8. Bosset JF, Magnin V, Maingon P, Mantion G, Pelissier EP, Mercier M, Chaillard G, Horiot JC. Preoperative radiochemotherapy in rectal cancer: Long-term results of a phase II trial. International Journal of Radiation Oncology Biology Physics 2000;46(2):323-327. (Pubitemid 30067781)
9. Bosset JF, Calais G, Daban A, Berger C, Radosevic-Jelic L, Maingon P, Bardet E, Pierart M, Briffaux A. Preoperative chemoradiotherapy versus preoperative radiotherapy in rectal cancer patients: assessment of acute toxicity and treatment compliance - Report of the 22921 randomised trial conducted by the EORTC Radiotherapy Group. European Journal of Cancer 2004;40(2):219-224. (Pubitemid 38077024)
10. Brown G, Kirkham A, Williams GT, Bourne M, Radcliffe AG, Sayman J, Newell R, Sinnatamby C, Heald RJ. High-resolution MRI of the anatomy important in total mesorectal excision of the rectum. American Journal of Roentgenology 2004;182(2):431-439. [: 0361-803X] (Pubitemid 38116588)
11. Brown G, Daniels IR, Heald RJ, Quirke P, Blomqvist L, Sebag-Montefiore D, Moran BJ, Holm T, Strassbourg J, Peppercorn PD, Fisher SE, Mason B. Diagnostic accuracy of preoperative magnetic resonance imaging in predicting curative resection of rectal cancer: prospective observational study. British Medical Journal 2006;333(7572):779-782. [: 0959-8146] (Pubitemid 44583356)
12. Dahlberg M, Glimelius B, Graf W, Pahlman L. Preoperative irradiation affects functional results after surgery for rectal cancer - Results from a randomized study. Diseases of the Colon & Rectum 1998;41(5):543-549. (Pubitemid 28224084)
13. Dale R, Carabe-Fernandez A. The radiobiology of conventional radiotherapy and its application to radionuclide therapy. CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS 2005;20(1):47-51. (Pubitemid 40478521)
14. Daniels IR. High spatial resolution MRI predicts turnout spread in patients with rectal cancer - Results from the MERCURY study. Diseases of the Colon & Rectum 2005;48(3):688-689.
15. Enker WE, Merchant N, Cohen AM, Lanouette NM, Swallow C, Guillem J, Paty P, Minsky B, Weyrauch K, Quan SHQ. Safety and efficacy of low anterior resection for rectal cancer - 681 consecutive cases from a specialty service. Annals of Surgery 1999;230(4):544-552. (Pubitemid 30191849)
16. Feliu J, Calvillo J, Escribano A, de Castro J, Sanchez ME, Mata A, Espinosa E, Grande AG, Mateo A, Baron MG. Neoadjuvant therapy of rectal carcinoma with UFT-leucovorin plus radiotherapy. Annals of Oncology 2002;13(5):730-736. (Pubitemid 34567379)
17. Glimelius B. Radiotherapy in rectal cancer. Br Med Bull 2002;64:141-157
18. Gray R, Hills R, Stowe R, Clarke M, Peto R, Buyse M, Piedbois P. Adjuvant radiotherapy for rectal cancer: a systematic overview of 8507 patients from 22 randomised trials. Lancet 2001;358(9290):1291-1304. (Pubitemid 33016492)
19. Heald RJ, Husband EM, Ryall RDH. The Mesorectum in Rectal-Cancer Surgery - the Clue to Pelvic Recurrence. British Journal of Surgery 1982;69(10):613-616. [: 0007-1323]
20. Heald RJ, Moran BJ, Ryall RDH, Sexton R, MacFarlane JK. Rectal cancer - The Basingstoke experience of total mesorectal excision, 1978-1997. Archives of Surgery 1998;133(8):894-898.
21. Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.0.0 [updated February 2008].. The Cochrane Collaboration. Available from www.cochrane-handbook.org. 2008.
22. Holm T, Singnomklao T, Rutqvist LE, Cedermark B. Adjuvant preoperative radiotherapy in patients with rectal carcinoma - Adverse effects during long term follow-up of two randomized trials. Cancer 1996;78(5):968-976. (Pubitemid 26284860)
23. Kapiteijn E, Marijnen CAM, Nagtegaal ID, Putter H, Steup WH, Wiggers T, Rutten HJT, Pahlman L, Glimelius B, van Krieken J, Leer JWH, van de Velde CJH. Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer. New England Journal of Medicine 2001;345(9):638-646. (Pubitemid 34936565)
24. Mercier M, Pasquet P, Puyraveau M, Bosset J, Calais G, Mineur L, Maingon P, Daban A, Bardet E, Collette L. Evaluation of the sphincter function and quality of life in French patients with rectal cancer who entered the EORTC 22921 study.. Eur J Cancer 2005;Supplements 3, No.2:171.
25. Minsky BD, Cohen AM, Kemeny N, Enker WE, Kelsen DP, Schwartz G, Saltz L, Dougherty J, Frankel J, Wiseberg J. Preoperative Combined 5-Fu, Low-Dose Leucovorin, and Sequential Radiation-Therapy for Unresectable Rectal-Cancer. International Journal of Radiation Oncology Biology Physics 1993;25(5):821-827. (Pubitemid 23123386)
26. Minsky BD, Cohen AM, Enker WE, Saltz L, Guillem JG, Paty PB, Kelsen DP, Kemeny N, Ilson D, Bass J, Conti J. Preoperative 5-FU, low-dose leucovorin, and radiation therapy for locally advanced and unresectable rectal cancer. International Journal of Radiation Oncology Biology Physics 1997;37(2):289-295. (Pubitemid 27138711)
27. Nagtegaal ID, Marijnen CAA, Kranenbarg EK, van de Velde CJH, van Krieken J. Circumferential margin involvement is still an important predictor of local recurrence in rectal carcinoma - Not one millimeter but two millimeters is the limit. American Journal of Surgical Pathology 2002;26(3):350-357.
28. Osti MF, Valeriani M, Masoni L, Tombolini V, Enrici RM. Neoadjuvant chemoradiation for locally advanced carcinoma of the rectum. Tumori 2004;90(3):303-309. (Pubitemid 38981277)
29. Peeters K, van de Velde CJH, Leer JWH, Martijn H, Junggeburt JMC, Kranenbarg EK, Steup WH, Wiggers T, Rutten HJ, Marijnen CAM. Late side effects of short-course preoperative radiotherapy combined with total mesorectal excision for rectal cancer: Increased bowel dysfunction in irradiated patients - A dutch colorectal cancer group study. Journal of Clinical Oncology 2005;23(25):6199-6206. (Pubitemid 46300239)
30. Quirke P, Dixon MF, Durdey P, Williams NS. Local Recurrence of Rectal Adenocarcinoma Due to Inadequate Surgical Resection - Histopathological Study of Lateral Tumor Spread and Surgical Excision. Lancet 1986;2(8514):996-999. [: 0140-6736] (Pubitemid 16005611)
31. Quirke P. Training and quality assurance for rectal cancer: 20 years of data is enough. Lancet Oncology 2003;4(11):695-702. (Pubitemid 37407437)
32. Rodel C, Grabenbauer GG, Papadopoulos T, Hohenberger W, Schmoll HJ, Sauer R. Phase I/II trial of capecitabine, oxaliplatin, and radiation for rectal cancer. Journal of Clinical Oncology 2003;21(16):3098-3104. (Pubitemid 46613485)
33. Sauer R, Becker H, Hohenberger W, Rodel C, Wittekind C, Fietkau R, Martus P, Tschmelitsch J, Hager E, Hess CF, Karstens JH, Liersch T, Schmidberger H, Raab R. Preoperative versus postoperative chemoradiotherapy for rectal cancer. New England Journal of Medicine 2004;351(17):1731-1740. (Pubitemid 39383208)
34. van den Brink M, Stiggelbout AM, van den Hout WB, Kievit J, Kranenbarg EK, Marijnen CAM, Nagtegaal ID, Rutten HJT, Wiggers T, van de Velde CJH. Clinical nature and prognosis of locally recurrent rectal cancer after total mesorectal excision with or without preoperative radiotherapy. Journal of Clinical Oncology 2004;22(19): 3958-3964. [: 0732-183X] (Pubitemid 41079878)