메뉴 건너뛰기




Volumn 167, Issue 6, 2013, Pages 2765-2774

Valsartan impairs angiogenesis of mesenchymal stem cells through Akt pathway

Author keywords

Akt; Angiogenesis; Angiotensin II; Stem cells

Indexed keywords

1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDRO 1H IMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANGIOTENSIN II; ANGIOTENSIN RECEPTOR ANTAGONIST; BUPRENORPHINE; ENHANCED GREEN FLUORESCENT PROTEIN; ISOPROTEIN; PROTEIN KINASE B; SERINE; VALSARTAN; VASCULOTROPIN; WORTMANNIN;

EID: 84883794121     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2012.06.128     Document Type: Article
Times cited : (8)

References (45)
  • 1
    • 0038701741 scopus 로고    scopus 로고
    • Transendocardial, autologous bone marrow cell transplantation for severe, chronic ischemic heart failure
    • E.C. Perin, H.F. Dohmann, and R. Borojevic Transendocardial, autologous bone marrow cell transplantation for severe, chronic ischemic heart failure Circulation 107 2003 2294 2302
    • (2003) Circulation , vol.107 , pp. 2294-2302
    • Perin, E.C.1    Dohmann, H.F.2    Borojevic, R.3
  • 2
    • 0346995399 scopus 로고    scopus 로고
    • Autologous mesenchymal stem cell transplantation induce VEGF and neovascularization in ischemic myocardium
    • Y.L. Tang, Q. Zhao, and Y.C. Zhang Autologous mesenchymal stem cell transplantation induce VEGF and neovascularization in ischemic myocardium Regul Pept 117 2004 3 10
    • (2004) Regul Pept , vol.117 , pp. 3-10
    • Tang, Y.L.1    Zhao, Q.2    Zhang, Y.C.3
  • 3
    • 33746092455 scopus 로고    scopus 로고
    • Mutual, reciprocal SDF-1/CXCR4 interactions between hematopoietic and bone marrow stromal cells regulate human stem cell migration and development in NOD/SCID chimeric mice
    • A. Dar, O. Kollet, and T. Lapidot Mutual, reciprocal SDF-1/CXCR4 interactions between hematopoietic and bone marrow stromal cells regulate human stem cell migration and development in NOD/SCID chimeric mice Exp Hematol 34 2006 967 975
    • (2006) Exp Hematol , vol.34 , pp. 967-975
    • Dar, A.1    Kollet, O.2    Lapidot, T.3
  • 4
    • 27644450590 scopus 로고    scopus 로고
    • Soluble factor cross-talk between human bone marrow-derived hematopoietic and mesenchymal cells enhances in vitro CFU-F and CFU-O growth and reveals heterogeneity in the mesenchymal progenitor cell compartment
    • D. Baksh, J.E. Davies, and P.W. Zandstra Soluble factor cross-talk between human bone marrow-derived hematopoietic and mesenchymal cells enhances in vitro CFU-F and CFU-O growth and reveals heterogeneity in the mesenchymal progenitor cell compartment Blood 106 2005 3012 3019
    • (2005) Blood , vol.106 , pp. 3012-3019
    • Baksh, D.1    Davies, J.E.2    Zandstra, P.W.3
  • 5
    • 21344471489 scopus 로고    scopus 로고
    • Gene expression profile of cytokine and growth factor during differentiation of bone marrow-derived mesenchymal stem cell
    • D.H. Kim, K.H. Yoo, and K.S. Choi Gene expression profile of cytokine and growth factor during differentiation of bone marrow-derived mesenchymal stem cell Cytokine 31 2005 119 126
    • (2005) Cytokine , vol.31 , pp. 119-126
    • Kim, D.H.1    Yoo, K.H.2    Choi, K.S.3
  • 6
    • 33745449058 scopus 로고    scopus 로고
    • In vitro endothelial potential of human UC blood-derived mesenchymal stem cells
    • E.J. Gang, J.A. Jeong, and S. Han In vitro endothelial potential of human UC blood-derived mesenchymal stem cells Cytotherapy 8 2006 215 227
    • (2006) Cytotherapy , vol.8 , pp. 215-227
    • Gang, E.J.1    Jeong, J.A.2    Han, S.3
  • 7
    • 4143128861 scopus 로고    scopus 로고
    • Bone-marrow-derived cells for enhancing collateral development: Mechanisms, animal data, and initial clinical experiences
    • T. Kinnaird, E. Stabile, M.S. Burnett, and S.E. Epstein Bone-marrow-derived cells for enhancing collateral development: mechanisms, animal data, and initial clinical experiences Circ Res 95 2004 354 363
    • (2004) Circ Res , vol.95 , pp. 354-363
    • Kinnaird, T.1    Stabile, E.2    Burnett, M.S.3    Epstein, S.E.4
  • 8
    • 2942572769 scopus 로고    scopus 로고
    • Therapeutic angiogenesis and vasculogenesis for ischemic disease: Part II: Cell-based therapies
    • D.W. Losordo, and S. Dimmeler Therapeutic angiogenesis and vasculogenesis for ischemic disease: part II: cell-based therapies Circulation 109 2004 2692 2697
    • (2004) Circulation , vol.109 , pp. 2692-2697
    • Losordo, D.W.1    Dimmeler, S.2
  • 9
    • 3242707692 scopus 로고    scopus 로고
    • Heart failure: How important is cellular sequestration? the role of the renin-angiotensin-aldosterone system
    • W.C. De Mello Heart failure: how important is cellular sequestration? The role of the renin-angiotensin-aldosterone system J Mol Cell Cardiol 37 2004 431 438
    • (2004) J Mol Cell Cardiol , vol.37 , pp. 431-438
    • De Mello, W.C.1
  • 10
    • 0029562325 scopus 로고
    • Pathophysiological aspects of the renin-angiotensin-aldosterone system in acute myocardial infarction
    • H.J. Dargie, and J. Byrne Pathophysiological aspects of the renin-angiotensin-aldosterone system in acute myocardial infarction J Cardiovasc Risk 2 1995 389 395
    • (1995) J Cardiovasc Risk , vol.2 , pp. 389-395
    • Dargie, H.J.1    Byrne, J.2
  • 11
    • 34249062648 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibitors and coronary heart disease prevention
    • R. Donnelly, and G. Manning Angiotensin-converting enzyme inhibitors and coronary heart disease prevention J Renin Angiotensin Aldosterone Syst 8 2007 13 22
    • (2007) J Renin Angiotensin Aldosterone Syst , vol.8 , pp. 13-22
    • Donnelly, R.1    Manning, G.2
  • 12
    • 0034685168 scopus 로고    scopus 로고
    • Angiotensin II receptor antagonists
    • M. Burnier, and H.R. Brunner Angiotensin II receptor antagonists Lancet 355 2000 637 645
    • (2000) Lancet , vol.355 , pp. 637-645
    • Burnier, M.1    Brunner, H.R.2
  • 13
    • 0042878465 scopus 로고    scopus 로고
    • Pleiotropic effects of angiotensin II receptor blocker in hypertensive patients
    • K.K. Koh, J.Y. Ahn, and S.H. Han Pleiotropic effects of angiotensin II receptor blocker in hypertensive patients J Am Coll Cardiol 42 2003 905 910
    • (2003) J Am Coll Cardiol , vol.42 , pp. 905-910
    • Koh, K.K.1    Ahn, J.Y.2    Han, S.H.3
  • 14
    • 20044396179 scopus 로고    scopus 로고
    • Renin-angiotensin system modulates oxidative stress-induced endothelial cell apoptosis in rats
    • M. Akishita, K. Nagai, and H. Xi Renin-angiotensin system modulates oxidative stress-induced endothelial cell apoptosis in rats Hypertension 45 2005 1188 1193
    • (2005) Hypertension , vol.45 , pp. 1188-1193
    • Akishita, M.1    Nagai, K.2    Xi, H.3
  • 15
    • 33750818654 scopus 로고    scopus 로고
    • Efficacy of angiotensin receptor blockers in cardiovascular disease
    • A.P. Maggioni Efficacy of angiotensin receptor blockers in cardiovascular disease Cardiovasc Drugs Ther 20 2006 295 308
    • (2006) Cardiovasc Drugs Ther , vol.20 , pp. 295-308
    • Maggioni, A.P.1
  • 16
    • 23944519605 scopus 로고    scopus 로고
    • How to explain the differences between renin angiotensin system modulators
    • B.I. Levy How to explain the differences between renin angiotensin system modulators Am J Hypertens 18 2005 134S 141S
    • (2005) Am J Hypertens , vol.18
    • Levy, B.I.1
  • 17
    • 0037205287 scopus 로고    scopus 로고
    • Antiangiogenic effect of angiotensin II type 2 receptor in ischemia-induced angiogenesis in mice hindlimb
    • J.S. Silvestre, R. Tamarat, and T. Senbonmatsu Antiangiogenic effect of angiotensin II type 2 receptor in ischemia-induced angiogenesis in mice hindlimb Circ Res 90 2002 1072 1079
    • (2002) Circ Res , vol.90 , pp. 1072-1079
    • Silvestre, J.S.1    Tamarat, R.2    Senbonmatsu, T.3
  • 18
    • 11144237722 scopus 로고    scopus 로고
    • Dual effect of angiotensin-converting enzyme inhibition on angiogenesis in type 1 diabetic mice
    • T.G. Ebrahimian, R. Tamarat, and M. Clergue Dual effect of angiotensin-converting enzyme inhibition on angiogenesis in type 1 diabetic mice Arterioscler Thromb Vasc Biol 25 2005 65 70
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 65-70
    • Ebrahimian, T.G.1    Tamarat, R.2    Clergue, M.3
  • 19
    • 0038048067 scopus 로고    scopus 로고
    • Cell transplantation to improve ventricular function in the failing heart
    • G.H. Tang, P.W. Fedak, and T.M. Yau Cell transplantation to improve ventricular function in the failing heart Eur J Cardiothorac Surg 23 2003 907 916
    • (2003) Eur J Cardiothorac Surg , vol.23 , pp. 907-916
    • Tang, G.H.1    Fedak, P.W.2    Yau, T.M.3
  • 20
    • 1642373909 scopus 로고    scopus 로고
    • Marrow-derived stromal cells express genes encoding a broad spectrum of arteriogenic cytokines and promote in vitro and in vivo arteriogenesis through paracrine mechanisms
    • T. Kinnaird, E. Stabile, and M.S. Burnett Marrow-derived stromal cells express genes encoding a broad spectrum of arteriogenic cytokines and promote in vitro and in vivo arteriogenesis through paracrine mechanisms Circ Res 94 2004 678 685
    • (2004) Circ Res , vol.94 , pp. 678-685
    • Kinnaird, T.1    Stabile, E.2    Burnett, M.S.3
  • 21
    • 33947305414 scopus 로고    scopus 로고
    • Adult bone marrow-derived cells for cardiac repair: A systematic review and meta-analysis
    • A. Abdel-Latif, R. Bolli, and I.M. Tleyjeh Adult bone marrow-derived cells for cardiac repair: a systematic review and meta-analysis Arch Intern Med 167 2007 989 997
    • (2007) Arch Intern Med , vol.167 , pp. 989-997
    • Abdel-Latif, A.1    Bolli, R.2    Tleyjeh, I.M.3
  • 22
    • 29444454634 scopus 로고    scopus 로고
    • Clinical trials update from the American Heart Association: REPAIR-AMI, ASTAMI, JELIS, MEGA, REVIVE-II, SURVIVE, and PROACTIVE
    • J.G. Cleland, N. Freemantle, A.P. Coletta, and A.L. Clark Clinical trials update from the American Heart Association: REPAIR-AMI, ASTAMI, JELIS, MEGA, REVIVE-II, SURVIVE, and PROACTIVE Eur J Heart Fail 8 2006 105 110
    • (2006) Eur J Heart Fail , vol.8 , pp. 105-110
    • Cleland, J.G.1    Freemantle, N.2    Coletta, A.P.3    Clark, A.L.4
  • 23
    • 3042748331 scopus 로고    scopus 로고
    • Renin-angiotensin system expression in rat bone marrow haematopoietic and stromal cells
    • W.B. Strawn, R.S. Richmond, and E. Ann Tallant Renin-angiotensin system expression in rat bone marrow haematopoietic and stromal cells Br J Haematol 126 2004 120 126
    • (2004) Br J Haematol , vol.126 , pp. 120-126
    • Strawn, W.B.1    Richmond, R.S.2    Ann Tallant, E.3
  • 24
    • 5644304340 scopus 로고    scopus 로고
    • How hematopoietic stem cells know and act in cardiac microenvironment for stem cell plasticity? Impact of local renin-angiotensin systems
    • M.A. Ozturk, G.S. Guven, and I.C. Haznedaroglu How hematopoietic stem cells know and act in cardiac microenvironment for stem cell plasticity? Impact of local renin-angiotensin systems Med Hypotheses 63 2004 866 874
    • (2004) Med Hypotheses , vol.63 , pp. 866-874
    • Ozturk, M.A.1    Guven, G.S.2    Haznedaroglu, I.C.3
  • 25
    • 0033855018 scopus 로고    scopus 로고
    • Effect of angiotensin II on hematopoietic progenitor cell proliferation
    • K.E. Rodgers, S. Xiong, R. Steer, and G.S. diZerega Effect of angiotensin II on hematopoietic progenitor cell proliferation Stem Cells 18 2000 287 294
    • (2000) Stem Cells , vol.18 , pp. 287-294
    • Rodgers, K.E.1    Xiong, S.2    Steer, R.3    Dizerega, G.S.4
  • 26
    • 1442332442 scopus 로고    scopus 로고
    • Adult stem cells from bone marrow (MSCs) isolated from different strains of inbred mice vary in surface epitopes, rates of proliferation, and differentiation potential
    • A. Peister, J.A. Mellad, and B.L. Larson Adult stem cells from bone marrow (MSCs) isolated from different strains of inbred mice vary in surface epitopes, rates of proliferation, and differentiation potential Blood 103 2004 1662 1668
    • (2004) Blood , vol.103 , pp. 1662-1668
    • Peister, A.1    Mellad, J.A.2    Larson, B.L.3
  • 27
    • 21844473275 scopus 로고    scopus 로고
    • High-throughput RNAi screening in vitro: From cell lines to primary cells
    • D. Ovcharenko, R. Jarvis, and S. Hunicke-Smith High-throughput RNAi screening in vitro: from cell lines to primary cells RNA 11 2005 985 993
    • (2005) RNA , vol.11 , pp. 985-993
    • Ovcharenko, D.1    Jarvis, R.2    Hunicke-Smith, S.3
  • 28
    • 33748850756 scopus 로고    scopus 로고
    • Beraprost sodium enhances neovascularization in ischemic myocardium by mobilizing bone marrow cells in rats
    • Y. Miyahara, S. Ohnishi, and H. Obata Beraprost sodium enhances neovascularization in ischemic myocardium by mobilizing bone marrow cells in rats Biochem Biophys Res Commun 349 2006 1242 1249
    • (2006) Biochem Biophys Res Commun , vol.349 , pp. 1242-1249
    • Miyahara, Y.1    Ohnishi, S.2    Obata, H.3
  • 29
    • 34347269599 scopus 로고    scopus 로고
    • Hyaluronan mixed esters of butyric and retinoic acid drive cardiac and endothelial fate in term placenta human mesenchymal stem cells and enhance cardiac repair in infarcted rat hearts
    • C. Ventura, S. Cantoni, and F. Bianchi Hyaluronan mixed esters of butyric and retinoic acid drive cardiac and endothelial fate in term placenta human mesenchymal stem cells and enhance cardiac repair in infarcted rat hearts J Biol Chem 282 2007 14243 14252
    • (2007) J Biol Chem , vol.282 , pp. 14243-14252
    • Ventura, C.1    Cantoni, S.2    Bianchi, F.3
  • 30
    • 1842486565 scopus 로고    scopus 로고
    • Local delivery of marrow-derived stromal cells augments collateral perfusion through paracrine mechanisms
    • T. Kinnaird, E. Stabile, and M.S. Burnett Local delivery of marrow-derived stromal cells augments collateral perfusion through paracrine mechanisms Circulation 109 2004 1543 1549
    • (2004) Circulation , vol.109 , pp. 1543-1549
    • Kinnaird, T.1    Stabile, E.2    Burnett, M.S.3
  • 31
    • 22244492929 scopus 로고    scopus 로고
    • Signaling factors in stem cell-mediated repair of infarcted myocardium
    • S. Vandervelde, M.J. van Luyn, R.A. Tio, and M.C. Harmsen Signaling factors in stem cell-mediated repair of infarcted myocardium J Mol Cell Cardiol 39 2005 363 376
    • (2005) J Mol Cell Cardiol , vol.39 , pp. 363-376
    • Vandervelde, S.1    Van Luyn, M.J.2    Tio, R.A.3    Harmsen, M.C.4
  • 32
    • 0035851219 scopus 로고    scopus 로고
    • Proangiogenic effect of angiotensin-converting enzyme inhibition is mediated by the bradykinin B(2) receptor pathway
    • J.S. Silvestre, S. Bergaya, and R. Tamarat Proangiogenic effect of angiotensin-converting enzyme inhibition is mediated by the bradykinin B(2) receptor pathway Circ Res 89 2001 678 683
    • (2001) Circ Res , vol.89 , pp. 678-683
    • Silvestre, J.S.1    Bergaya, S.2    Tamarat, R.3
  • 33
    • 33646593556 scopus 로고    scopus 로고
    • Thromboxane A2/prostaglandin H2 receptor activation mediates angiotensin II-induced postischemic neovascularization
    • F. Michel, J.S. Silvestre, and L. Waeckel Thromboxane A2/prostaglandin H2 receptor activation mediates angiotensin II-induced postischemic neovascularization Arterioscler Thromb Vasc Biol 26 2006 488 493
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 488-493
    • Michel, F.1    Silvestre, J.S.2    Waeckel, L.3
  • 34
    • 0036197119 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase lies downstream from angiotensin II-induced angiogenesis in ischemic hindlimb
    • R. Tamarat, J.S. Silvestre, and N. Kubis Endothelial nitric oxide synthase lies downstream from angiotensin II-induced angiogenesis in ischemic hindlimb Hypertension 39 2002 830 835
    • (2002) Hypertension , vol.39 , pp. 830-835
    • Tamarat, R.1    Silvestre, J.S.2    Kubis, N.3
  • 35
    • 0036199933 scopus 로고    scopus 로고
    • Evidence for the importance of angiotensin II type 1 receptor in ischemia-induced angiogenesis
    • K. Sasaki, T. Murohara, and H. Ikeda Evidence for the importance of angiotensin II type 1 receptor in ischemia-induced angiogenesis J Clin Invest 109 2002 603 611
    • (2002) J Clin Invest , vol.109 , pp. 603-611
    • Sasaki, K.1    Murohara, T.2    Ikeda, H.3
  • 36
    • 34247844373 scopus 로고    scopus 로고
    • Angiotensin II induces angiogenesis in the hypoxic adult mouse heart in vitro through an AT2-B2 receptor pathway
    • V.C. Munk, L. Sanchez de Miguel, and M. Petrimpol Angiotensin II induces angiogenesis in the hypoxic adult mouse heart in vitro through an AT2-B2 receptor pathway Hypertension 49 2007 1178 1185
    • (2007) Hypertension , vol.49 , pp. 1178-1185
    • Munk, V.C.1    Sanchez De Miguel, L.2    Petrimpol, M.3
  • 37
    • 33751533938 scopus 로고    scopus 로고
    • Activation of endothelial nitric oxide synthase by the angiotensin II type 1 receptor
    • H. Suzuki, K. Eguchi, and H. Ohtsu Activation of endothelial nitric oxide synthase by the angiotensin II type 1 receptor Endocrinology 147 2006 5914 5920
    • (2006) Endocrinology , vol.147 , pp. 5914-5920
    • Suzuki, H.1    Eguchi, K.2    Ohtsu, H.3
  • 38
    • 33744758028 scopus 로고    scopus 로고
    • The role of PI3K/AKT, MAPK/ERK and NFkappabeta signalling in the maintenance of human embryonic stem cell pluripotency and viability highlighted by transcriptional profiling and functional analysis
    • L. Armstrong, O. Hughes, and S. Yung The role of PI3K/AKT, MAPK/ERK and NFkappabeta signalling in the maintenance of human embryonic stem cell pluripotency and viability highlighted by transcriptional profiling and functional analysis Hum Mol Genet 15 2006 1894 1913
    • (2006) Hum Mol Genet , vol.15 , pp. 1894-1913
    • Armstrong, L.1    Hughes, O.2    Yung, S.3
  • 39
    • 34247569333 scopus 로고    scopus 로고
    • ANG II-stimulated DNA synthesis is mediated by ANG II receptor-dependent Ca(2 +)/PKC as well as EGF receptor-dependent PI3K/Akt/mTOR/p70S6K1 signal pathways in mouse embryonic stem cells
    • H.J. Han, J.Y. Han, and J.S. Heo ANG II-stimulated DNA synthesis is mediated by ANG II receptor-dependent Ca(2 +)/PKC as well as EGF receptor-dependent PI3K/Akt/mTOR/p70S6K1 signal pathways in mouse embryonic stem cells J Cell Physiol 211 2007 618 629
    • (2007) J Cell Physiol , vol.211 , pp. 618-629
    • Han, H.J.1    Han, J.Y.2    Heo, J.S.3
  • 40
    • 56949100242 scopus 로고    scopus 로고
    • Angiotensin II induces vascular endothelial growth factor synthesis in mesenchymal stem cells
    • R.Z. Shi, J.C. Wang, and S.H. Huang Angiotensin II induces vascular endothelial growth factor synthesis in mesenchymal stem cells Exp Cell Res 315 2009 10 15
    • (2009) Exp Cell Res , vol.315 , pp. 10-15
    • Shi, R.Z.1    Wang, J.C.2    Huang, S.H.3
  • 41
    • 33646252939 scopus 로고    scopus 로고
    • Evidence supporting paracrine hypothesis for Akt-modified mesenchymal stem cell-mediated cardiac protection and functional improvement
    • M. Gnecchi, H. He, and N. Noiseux Evidence supporting paracrine hypothesis for Akt-modified mesenchymal stem cell-mediated cardiac protection and functional improvement FASEB J 20 2006 661 669
    • (2006) FASEB J , vol.20 , pp. 661-669
    • Gnecchi, M.1    He, H.2    Noiseux, N.3
  • 42
    • 33947579076 scopus 로고    scopus 로고
    • Angiotensin receptor-1 blocker inhibits atherosclerotic changes and endothelial disruption of the aortic valve in hypercholesterolemic rabbits
    • K. Arishiro, M. Hoshiga, and N. Negoro Angiotensin receptor-1 blocker inhibits atherosclerotic changes and endothelial disruption of the aortic valve in hypercholesterolemic rabbits J Am Coll Cardiol 49 2007 1482 1489
    • (2007) J Am Coll Cardiol , vol.49 , pp. 1482-1489
    • Arishiro, K.1    Hoshiga, M.2    Negoro, N.3
  • 43
    • 12344268929 scopus 로고    scopus 로고
    • The angiotensin II receptor blocker candesartan cilexetil reduces neointima proliferation after coronary stent implantation: A prospective randomized study under intravascular ultrasound guidance
    • O. Yoshida, H. Hirayama, and M. Nanasato The angiotensin II receptor blocker candesartan cilexetil reduces neointima proliferation after coronary stent implantation: a prospective randomized study under intravascular ultrasound guidance Am Heart J 149 2005 e2
    • (2005) Am Heart J , vol.149 , pp. 2
    • Yoshida, O.1    Hirayama, H.2    Nanasato, M.3
  • 44
    • 15744382725 scopus 로고    scopus 로고
    • Effects of pre-, peri-, and postmyocardial infarction treatment with losartan in rats: Effect of dose on survival, ventricular arrhythmias, function, and remodeling
    • A. Pourdjabbar, T.G. Parker, and Q.T. Nguyen Effects of pre-, peri-, and postmyocardial infarction treatment with losartan in rats: effect of dose on survival, ventricular arrhythmias, function, and remodeling Am J Physiol Heart Circ Physiol 288 2005 H1997 H2005
    • (2005) Am J Physiol Heart Circ Physiol , vol.288
    • Pourdjabbar, A.1    Parker, T.G.2    Nguyen, Q.T.3
  • 45
    • 52249116778 scopus 로고    scopus 로고
    • Telmisartan to prevent recurrent stroke and cardiovascular events
    • S. Yusuf, H.C. Diener, and R.L. Sacco Telmisartan to prevent recurrent stroke and cardiovascular events N Engl J Med 359 2008 1225 1237
    • (2008) N Engl J Med , vol.359 , pp. 1225-1237
    • Yusuf, S.1    Diener, H.C.2    Sacco, R.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.