Defects in neutrophil granule mobilization and bactericidal activity in familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) syndrome caused by STXBP2/Munc18-2 mutations

Blood

Volumn 122, Issue 1, 2013, Pages 109-111

  Zhao, Xi Wen ^a   Gazendam, Roel P ^a   Drewniak, Agata ^a   Van Houdt, Michel ^a   Tool, Anton T J ^a   Van Hamme, John L ^a   Kustiawan, Iwan ^a   Meijer, Alexander B ^a,b   Janssen, Hans ^c   Russell, David G ^d   Van De Corput, Lisette ^e   Tesselaar, Kiki ^e   Boelens, Jaap J ^e   Kuhnle, Ingrid ^f   Van Der Werff Ten Bosch, Jutte ^g   Kuijpers, Taco W ^a   Van Den Berg, Timo K ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c NETHERLANDS CANCER INSTITUTE   (Netherlands)

^d Animal Health Diagnostic Center   (United States)

^e UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^f UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^g UNIVERSITY HOSPITAL BRUSSELS   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CYTOCHALASIN B; DOCKING PROTEIN; FORMYLMETHIONYLLEUCYLPHENYLALANINE; GELATINASE; LACTOFERRIN; MUNC18 PROTEIN; MYELOPEROXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SYNTAXIN BINDING PROTEIN 2; UNCLASSIFIED DRUG; STXBP2 PROTEIN, HUMAN;

ADULT; ARTICLE; BACTERIAL SURVIVAL; BACTERICIDAL ACTIVITY; BACTERIUM COLONY; CONTROLLED STUDY; ENZYME ACTIVITY; ESCHERICHIA COLI; EXOCYTOSIS; EXON; FAMILIAL HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS TYPE 5; GENE MUTATION; HEMOPHAGOCYTIC SYNDROME; HUMAN; HUMAN CELL; IMMOBILIZED CELL; NATURAL KILLER CELL; NEUTROPHIL GRANULE; PRIORITY JOURNAL; PROTEIN DEGRADATION; STAPHYLOCOCCUS AUREUS; CELL GRANULE; DEGRANULATION; ESCHERICHIA COLI INFECTION; FEMALE; GASTROENTERITIS; GENETIC PREDISPOSITION; GENETICS; IMMUNOLOGY; MALE; METABOLISM; MICROBIOLOGY; NEUTROPHIL; STAPHYLOCOCCUS INFECTION;

CELL DEGRANULATION; CYTOPLASMIC GRANULES; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; FEMALE; GASTROENTERITIS; GENETIC PREDISPOSITION TO DISEASE; HUMANS; KILLER CELLS, NATURAL; LYMPHOHISTIOCYTOSIS, HEMOPHAGOCYTIC; MALE; MUNC18 PROTEINS; NEUTROPHILS; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS;

EID: 84883787003     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2013-03-494039     Document Type: Article

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