Amelioration in wound healing in diabetic toll-like receptor-4 knockout mice

Journal of Diabetes and its Complications

Volumn 27, Issue 5, 2013, Pages 417-421

  Dasu, Mohan R ^a   Jialal, Ishwarlal ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Diabetes; Inflammation; Mellitus; TLR4; Wound healing

Indexed keywords

STREPTOZOCIN; TOLL LIKE RECEPTOR 4;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE ACTIVATION; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; STREPTOZOCIN DIABETES; WESTERN BLOTTING; WOUND HEALING;

DIABETES MELLITUS; INFLAMMATION; TLR4; WOUND HEALING;

ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; INFLAMMATION; LYMPHOCYTE ANTIGEN 96; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; STREPTOZOCIN; TOLL-LIKE RECEPTOR 4; WOUND HEALING;

EID: 84883762352     PISSN: 10568727     EISSN: 1873460X     Source Type: Journal    
DOI: 10.1016/j.jdiacomp.2013.05.002     Document Type: Article

References (25)

1. J.B. Acosta, D.G. del Barco, D.C. Vera, W. Savigne, P. Lopez-Saura, and G.G. Nieto The pro-inflammatory environment in recalcitrant diabetic foot wounds International Wound Journal 5 4 2008 530 539
2. B. Beutler TLR4 as the mammalian endotoxin sensor Current Topics in Microbiology and Immunology 270 2002 109 120
3. J.W. Breslin, M.H. Wu, M. Guo, R. Reynoso, and S.Y. Yuan Toll-like receptor 4 contributes to microvascular inflammation and barrier dysfunction in thermal injury Shock 29 3 2008 349 355
4. P.D. Cani, R. Bibiloni, C. Knauf, A. Waget, A.M. Neyrinck, and N.M. Delzenne Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice Diabetes 57 2008 1470 1481
5. L. Chen, S. Guo, M.J. Ranzer, and L.A. Dipietro Toll-like receptor 4 has an essential role in early skin wound healing The Journal of Investigative Dermatology 133 1 2013 258 267
6. G. Danaei, M.M. Finucane, Y. Lu, G.M. Singh, M.J. Cowan, and C.J. Paciorek National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2.7 million participants The Lancet 378 9785 2011 31 40
7. P. Dandona, H. Ghanim, K. Green, C.L. Sia, S. Abuaysheh, and N. Kuhadiya Insulin infusion suppresses while glucose infusion induces Toll-like receptors and high-mobility group-B1 protein expression in mononuclear cells of type 1 diabetes patients American Journal of Physiology, Endocrinology and Metabolism 304 8 2013 E810 E818
8. M.R. Dasu, S. Devaraj, L. Zhao, D.H. Hwang, and I. Jialal High glucose induces toll-like receptor expression in human monocytes: Mechanism of activation Diabetes 57 2008 3090 3098
9. M.R. Dasu, R. Thangappan, A. Bourgette, L.A. DiPietro, R. Isseroff, and I. Jialal TLR2 expression and signaling dependent inflammation impair wound healing in diabetic mice Laboratory Investigation 90 11 2010 1628 1636
10. S. Devaraj, M.R. Dasu, J. Rockwood, W. Winter, S.C. Griffen, and I. Jialal Increased toll like receptor (TLR) 2 and TLR4 expression in monocytes from patients with type 1 diabetes: Further evidence of a proinflammatory state The Journal of Clinical Endocrinology and Metabolism 93 2008 578 583
11. S. Devaraj, P. Tobias, and I. Jialal Knock-out of TLR4 attenuates the pro-inflammatory state of diabetes Cytokine 55 2011 441 445
12. S.A. Eming, T. Krieg, and J.M. Davidson Inflammation in wound repair: Molecular and cellular mechanisms The Journal of Investigative Dermatology 127 2007 514 525
13. H. Ghanim, S. Abuaysheh, C.L. Sia, K. Korzeniewski, A. Chaudhuri, and J.M. Fernandez-Real Increase in plasma endotoxin concentrations and the expression of Toll-like receptors and suppressor of cytokine signaling-3 in mononuclear cells after a high-fat, high-carbohydrate meal: Implications for insulin resistance Diabetes Care 32 12 2009 2281 2287
14. H. Ghanim, K. Korzeniewski, C.L. Sia, S. Abuaysheh, T. Lohano, and A. Chaudhuri Suppressive effect of insulin infusion on chemokines and chemokine receptors Diabetes Care 33 5 2010 1103 1108
15. W.J. Jeffcoate, and K.G. Harding Diabetic foot ulcers The Lancet 361 2003 1545 1551
16. I. Jialal, and H. Kaur The role of toll-like receptors in diabetes-induced inflammation: Implications for vascular complications Current Diabetes Reports 2012 [Epub ahead of print]
17. M. Lin, W.H. Yiu, H.J. Wu, L.Y. Chan, J.C. Leung, and W.S. Au Toll-like receptor 4 promotes tubular inflammation in diabetic nephropathy Journal of the American Society of Nephrology 23 1 2012 86 102
18. R. Liu, H.S. Bal, T. Desta, Y. Behl, and D.T. Graves Tumor necrosis factor-α mediates diabetes-enhanced apoptosis of matrix-producing cells and impairs diabetic healing The American Journal of Pathology 168 3 2006 757 764
19. K.P. Mollen, R.J. Anand, A. Tsung, J.M. Prince, R.M. Levy, and T.R. Billiar Emerging paradigm: Toll-like receptor 4-sentinel for the detection of tissue damage Shock 26 5 2006 430 437
20. S.R. Ramirez, and M.R. Dasu Toll-like receptors and diabetes complications: Recent advances Current Diabetes Reviews 8 6 2012 480 488
21. H. Shi, M.V. Kokoeva, K. Inouye, I. Tzameli, H. Yin, and J.S. Flier TLR4 links innate immunity and fatty acid-induced insulin resistance The Journal of Clinical Investigation 116 11 2006 3015 3025
22. R.G. Sibbald, and K.Y. Woo The biology of chronic foot ulcers in persons with DM Diabetes/Metabolism Research and Reviews 24 1 2008 S25 S30
23. A. Sindrilaru, T. Peters, S. Wieschalka, C. Baican, A. Baican, and H. Peter An unrestrained proinflammatory M1 M∅ population induced by iron impairs wound healing in humans and mice The Journal of Clinical Investigation 121 3 2011 985 997
24. K.R. Taylor, J.M. Trowbridge, J.A. Rudisill, C.C. Termeer, J.C. Simon, and R.L. Gallo Hyaluronan fragments stimulate endothelial recognition of injury through TLR4 The Journal of Biological Chemistry 279 17 2004 17079 17084
25. S. Uematsu, and S. Akira Toll-like receptors and innate immunity Journal of Molecular Medicine 84 9 2006 712 725