Proline-rich tyrosine kinase 2 and its phosphorylated form pY881 are novel prognostic markers for non-small-cell lung cancer progression and patients' overall survival

British Journal of Cancer

Volumn 109, Issue 5, 2013, Pages 1252-1263

  Kuang, B H ^a   Zhang, M Q ^a   Xu, L H ^b   Hu, L J ^b   Wang, H B ^a   Zhao, W F ^c   Du, Y ^a   Zhang, X ^a  

^a SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^b GUANGZHOU MEDICAL UNIVERSITY   (China)

^c HENAN PROVINCIAL PEOPLE'S HOSPITAL   (China)

Author keywords

cancer stem cell; immunohistochemistry; non small cell lung cancer; phosphorylated Pyk2; prognosis; Pyk2

Indexed keywords

BMI1 PROTEIN; BREAST CANCER RESISTANCE PROTEIN; FOCAL ADHESION KINASE 2; MESSENGER RNA; TUMOR MARKER;

ADENOCARCINOMA; ADULT; ANCHORAGE INDEPENDENT GROWTH; ARTICLE; CANCER CELL CULTURE; CANCER GRADING; CANCER GROWTH; CANCER PROGNOSIS; CANCER STAGING; CANCER STEM CELL; CANCER SURVIVAL; CANCER TISSUE; COLONY FORMATION; CONTROLLED STUDY; FAR WESTERN BLOTTING; FEMALE; FOLLOW UP; HUMAN; IMMUNOHISTOCHEMISTRY; LUNG NON SMALL CELL CANCER; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SQUAMOUS CELL CARCINOMA; UPREGULATION;

ADULT; AGED; AGED, 80 AND OVER; ALDEHYDE DEHYDROGENASE; ATP-BINDING CASSETTE TRANSPORTERS; CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; DISEASE PROGRESSION; FEMALE; GENE KNOCKDOWN TECHNIQUES; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; NEOPLASM PROTEINS; PHOSPHORYLATION; POLYCOMB REPRESSIVE COMPLEX 1; RNA, MESSENGER; TREATMENT OUTCOME; TUMOR MARKERS, BIOLOGICAL; TYK2 KINASE; UP-REGULATION;

EID: 84883742615     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2013.439     Document Type: Article

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