Determination of pKa values of a triptolide derivative and its impurities by pressure-assisted capillary electrophoresis

Journal of Pharmaceutical and Biomedical Analysis

Volumn 88, Issue , 2014, Pages 22-26

  Wang, Jian Ling ^a   Xu, Xue Jiao ^a   Chen, Dong Ying ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Capillary electrophoresis; External pressure; Impurities; PKa; Potentiometric titration; Triptolide derivative

Indexed keywords

ACETIC ACID; BORIC ACID; FORMIC ACID; PHOSPHATE; SILICON DIOXIDE; TRIPTOLIDE; TROMETAMOL;

ARTICLE; CAPILLARY ELECTROPHORESIS; CAPILLARY ZONE ELECTROPHORESIS; CHEMICAL STRUCTURE; IONIC STRENGTH; PH; POTENTIOMETRIC TITRATION; PRESSURE; PRESSURE ASSISTED CAPILLARY ZONE ELECTROPHORESIS; PRIORITY JOURNAL;

CAPILLARY ELECTROPHORESIS; EXTERNAL PRESSURE; IMPURITIES; PK(A); POTENTIOMETRIC TITRATION; TRIPTOLIDE DERIVATIVE;

AUTOMATION; BUFFERS; CHEMISTRY, PHARMACEUTICAL; DITERPENES; DRUG DESIGN; ELECTROCHEMISTRY; ELECTROLYTES; ELECTROPHORESIS, CAPILLARY; EPOXY COMPOUNDS; HYDROGEN-ION CONCENTRATION; IMMUNOSUPPRESSIVE AGENTS; IONS; MODELS, CHEMICAL; OSMOLAR CONCENTRATION; PHENANTHRENES; PLANT EXTRACTS; PRESSURE; TRIPTERYGIUM;

EID: 84883718468     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2013.08.012     Document Type: Article

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