Ginsenoside Rd induces protective anti-Candida albicans antibody through immunological adjuvant activity

International Immunopharmacology

Volumn 17, Issue 3, 2013, Pages 651-657

  Han, Yongmoon ^a   Rhew, Ki Yon ^a  

^a Dongduk Women's University   (South Korea)

Author keywords

Adjuvant; C. albicans; Disseminated candidiasis; Ginsenoside Rd; Protective antibody; Th1 immunity

Indexed keywords

AMPHOTERICIN B; ANTIFUNGAL AGENT; CANDIDA ALBICANS ANTIBODY; FUNGUS ANTIBODY; GAMMA INTERFERON; GINSENOSIDE RD; IMMUNOLOGICAL ADJUVANT; INTERLEUKIN 4; UNCLASSIFIED DRUG;

ACTIVE IMMUNIZATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY PRODUCTION; ANTIBODY TITER; ANTIFUNGAL ACTIVITY; ARTICLE; CANDIDA ALBICANS; CIRCULATION; CONTROLLED STUDY; DELAYED HYPERSENSITIVITY; FEMALE; GINSENG; HEMOLYSIS; IMMUNE RESPONSE; INVASIVE CANDIDIASIS; KIDNEY PARENCHYMA; MOUSE; NONHUMAN; PASSIVE IMMUNIZATION; PRIORITY JOURNAL; SURVIVAL; TH1 CELL;

ADJUVANT; C. ALBICANS; DISSEMINATED CANDIDIASIS; GINSENOSIDE RD; PROTECTIVE ANTIBODY; TH1-IMMUNITY;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODIES, FUNGAL; CANDIDA ALBICANS; CANDIDIASIS; FEMALE; FREUND'S ADJUVANT; FUNGAL VACCINES; GINSENOSIDES; HYPERSENSITIVITY, DELAYED; IMMUNOGLOBULIN G; INTERFERON-GAMMA; INTERLEUKIN-4; MANNANS; MICE; MICE, INBRED BALB C;

EID: 84883714162     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2013.08.003     Document Type: Article

References (46)

1. G.P. Body The emergence of fungi as major hospital pathogens J Hosp Infect 11 Suppl. A 1988 411 426
2. J.E. Edwards Invasive Candida infections: evolution of a fungal pathogen N Engl J Med 324 1991 1060 1062
3. E.J. Anaissie, R.O. Darouiche, D. Abi-Said, O. Uzun, J. Mera, and L.O. Gentry Management of invasive candidal infections: results of a prospective, randomized, multicenter study of fluconazole versus amphotericin B and a review of the literature Clin Infect Dis 23 1996 964 972 (Pubitemid 26367478)
4. J.E. Edwards Jr., and S.G. Filler Current strategies for treating invasive candidiasis: emphasis on infections in nonneutropenic patients Clin Infect Dis 14 Suppl. 1 1992 S106 S113
5. Y. Han, and J.E. Cutler Antibody response that protects against disseminated candidiasis Infect Immun 63 1995 2714 2719
6. A. Cassone, M. Boccanera, D. Adriani, G. Santoni, and F. De Bernardis Rats clearing a vaginal infection by Candida albicans acquire specific, antibody-mediated resistance to vaginal reinfection Infect Immun 63 1995 2619 2624
7. P.J. Costantino, K.M. Franklyn, N.F. Gare, and J.R. Warmington Production of antibodies to antigens of Candida albicans in CBA/H mice Infect Immun 62 4 1994 1400 1405 (Pubitemid 24110834)
8. R.C. Matthews Pathogenicity determinants of Candida albicans: potential targets for immunotherapy? Microbiology 140 Pt 7 1994 1505 1511 (Pubitemid 24231138)
9. S. Mourad, and L. Frieman Active immunization of mice against Candida albicans Proc Soc Exp Biol Med 106 1961 570 572
10. S. Mourad, and L. Frieman Passive immunization of mice against Candida albicans Sauboraudia 6 1968 103 105
11. D. Tavares, P. Ferreira, M. Vilanova, A. Videira, and M. Arala-Chaves Immunoprotection against systemic candidiasis in mice Int Immunol 7 5 1995 785 796
12. A. Cassone, S. Conti, F. De Bernardis, and L. Polonelli Antibodies, killer toxins and antifungal immunoprotection: a lesson from nature? Immunol Today 18 4 1997 164 169 (Pubitemid 27192177)
13. Y. Han, and K.Y. Rhew Comparison of two Candida mannan vaccines: the role of complement in protection against disseminated candidiasis Arch Pharm Res 35 11 2012 2021 2027
14. Y. Han Efficacy of combination immunotherapy of IgM MAb B6.1 and amphotericin B against disseminated candidiasis Int Immunopharmacol 10 2010 1526 1531
15. Y. Han, R.P. Morrison, and J.E. Cutler A vaccine and monoclonal antibodies that enhance mouse resistance to Candida albicans vaginal infection Infect Immun 66 1998 5771 5776 (Pubitemid 28531833)
16. M.X. Zhang, J.E. Cutler, Y. Han, and T.R. Kozel Contrasting roles of mannan-specific monoclonal immunoglobulin M antibodies in the activation of classical and alternative pathways by Candida albicans Infect Immun 66 1998 6027 6029 (Pubitemid 28531871)
17. Y. Han, T.R. Kozel, M.X. Zhang, R.S. MacGill, M.C. Carroll, and J.E. Cutler Complement is essential for protection by an IgM and an IgG3 monoclonal antibody against experimental, hematogenously disseminated candidiasis J Immunol 167 2001 1550 1557 (Pubitemid 32703155)
18. Y. Han, M.A. Ulrich, and J.E. Cutler Candida albicans mannan extract-protein conjugates induce a protective immune response against experimental candidiasis J Infect Dis 179 1999 1477 1484 (Pubitemid 29246598)
19. R.P. Bucy, L. Karr, G.Q. Huang, J. Li, D. Carter, and K. Honjo Single cell analysis of cytokine gene coexpression during CD4 + T-cell phenotype development Proc Natl Acad Sci 92 1995 7565 7569
20. J.C. Cox, and A.R. Coulter Adjuvant - a classification and review of their mode of action Vaccine 5 1997 48 56
21. D.J. Herzyk, E.R. Gore, R. Polsky, K.L. Nadwodny, C.C. Maier, and S. Liu Immunomodulatory effects of anti-CD4 antibody in host resistance against infections and tumors in human CD4 transgenic mice Infect Immun 69 2001 1032 1043 (Pubitemid 32109571)
22. L.M. Lavigne, L.R. Schopf, C.L. Chung, R. Maylor, and J.P. Sypek The role of recombinant murine IL-12 and INF-g in the pathogenesis of murine systemic Candida albicans infection J Immunol 160 1998 284 292 (Pubitemid 28116740)
23. R.K. Gupta Aluminum compounds are vaccine adjuvants Adv Drug Deliv Rev 32 1998 155 172 (Pubitemid 28267407)
24. D.W. Macy Vaccine adjuvants Semin Vet Med Surg (Small Anim) 12 1997 206 211 (Pubitemid 127789293)
25. J.M. Dan, and S.M. Levitz Prospects for development of vaccines against fungal diseases Drug Resist Updat 9 2006 105 110 [Review] (Pubitemid 44279522)
26. R.G. Iannitti, A. Carvalho, and L. Romani From memory to antifungal vaccine design Trends Immunol 33 2012 467 474 [Review]
27. A.G. Vonk, M.G. Netea, J.W. van der Meer, and B.J. Kullberg Host defence against disseminated Candida albicans infection and implications for antifungal immunotherapy Expert Opin Biol Ther 6 2006 891 903 [Review]
28. U. Sonnenborn, and Y. Proppert Ginseng (Panax ginseng C. A. Meyer) Br J Phytother 2 1991 3 14
29. K.C. Huang The Pharmacology of Chinese Herbs 1999 CRC Press Boca Raton, FL
30. I. Joo, H. Kim, J. Kim, S. Omer, Y.S. Kim, and Y. Han Immunoregulatory effect of ginsenosides Rd and Rg1 on proliferation of B cells and antibody induction Yakhak Hoeji 57 2013 1 7
31. Z. Yang, A. Chen, H. Sun, Y. Ye, and W. Fang Ginsenoside Rd elicits Th1 and Th2 immune responses to ovalbumin in mice Vaccine 25 2007 161 169 (Pubitemid 44855238)
32. K.C. Hazen, D.L. Brawner, M.H. Riesselman, M.A. Jutila, and J.E. Cutler Differential adherence of hydrophobic and hydrophilic Candida albicans yeast cells to mouse tissues Infect Immun 59 3 1991 907 912
33. T. Kanbe, and J.E. Cutler Evidence for adhesin activity in the acid-stable moiety of the phosphomannoprotein cell wall complex of Candida albicans Infect Immun 62 5 1994 1662 1668 (Pubitemid 24136961)
34. O. Shehzad, H.P. Kim, and Y.S. Kim State-of-the-art separation of ginsenosides from Korean white and red ginseng by countercurrent chromatography Anal Bioanal Chem 405 13 2013 4523 4530
35. Y. Han Ginkgo terpene component has an anti-inflammatory effect on Candida albicans-caused arthritis Int Immunopharmacol 5 2005 1049 1056
36. T. Kanbe, Y. Han, B. Redgrave, M.H. Riesselman, and J.E. Cutler Evidence that mannans of Candida albicans are responsible for adherence of yeast forms to spleen and lymph node tissue Infect Immun 61 6 1993 2578 2584 (Pubitemid 23159253)
37. D.B. Louria, R.G. Brayton, and G. Finkel Studies on the pathogenesis of experimental Candida albicans infections in mice Sabouraudia 268 1963 271 283
38. T. Sieck, M.A. Moors, H.R. Buckley, and K.J. Blank Protection against murine disseminated candidiasis mediated by a Candida albicans-specific T-cell line Infect Immun 61 1993 3540 3543 (Pubitemid 23223452)
39. K.I. Rhew, and Y. Han Immunoadjuvant activity of icariin that induces Th1-type antibody in mice Arch Pharm Res 35 2012 1685 1691
40. J.H. Lee, J.H. Park, Y.S. Kim, and Y. Han Chlorogenic acid, a polyphenolic compound, treat mice with septic arthritis caused by Candida albicans Int Immunopharmacol 8 2008 681 685
41. Y. Han, M.H. Riesselman, and J.E. Cutler Protection against candidiasis by an Immunoglobulin G3 (IgG3) monoclonal antibody specific for the same mannotriose as an IgM protective antibody Infect Immun 68 2000 1649 1654 (Pubitemid 30108568)
42. J.H. Lee, and Y. Han Ginsenoside Rg1 helps mice resist to disseminated candidiasis by Th1 type differentiation of CD4 + T cell Int Immunopharmacol 6 2006 1424 1430 (Pubitemid 44038684)
43. J. Kim, B.J. Han, H. Kim, J.Y. Lee, I. Joo, and S. Omer Th1 immunity induction by ginsenoside Re involves in protection of mice against disseminated candidiasis due to Candida albicans Int Immunopharmacol 14 4 2012 481 486
44. D.H. Cribbs, A. Ghochikyan, V. Vasilevko, M. Tran, I. Petrushina, and N. Sadzikava Adjuvant-dependent modulation of Th1 and Th2 responses to immunization with beta-amyloid Int Immunol 15 2003 505 514 (Pubitemid 36432403)
45. H.C. Yip, A.Y. Karulin, M. Tary-Lehmann, M.D. Hesse, H. Radeke, and P.S. Heeger Adjuvant-guided type-1 and type-2 immunity: infectious/noninfectious dichotomy defines the class of response J Immunol 162 1999 3942 3949 (Pubitemid 29314773)
46. J. Sun, S. Hu, and X. Song Adjuvant effects of protopanaxadiol and protopanaxatriol saponins from ginseng roots on the immune response to ovalbumin in mice Vaccine 25 2007 1114 1120 (Pubitemid 44937445)