Hyperinsulinemia stimulates angiogenesis of human fetoplacental endothelial cells: A possible role of insulin in placental hypervascularization in diabetes mellitus

Journal of Clinical Endocrinology and Metabolism

Volumn 98, Issue 9, 2013, Pages

  Lassance, Luciana ^a   Miedl, Heidi ^a   Absenger, Markus ^a   Diaz Perez, Francisca ^a   Lang, Uwe ^a   Desoye, Gernot ^a   Hiden, Ursula ^a  

^a MEDICAL UNIVERSITY OF GRAZ   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLYCOGEN SYNTHASE KINASE 3BETA; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NITRIC OXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RAC1 PROTEIN;

ANGIOGENESIS; ARTICLE; BIOLOGICAL ACTIVITY; CELL COUNT; CELL CYCLE; CELL PROLIFERATION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FETOPLACENTAL UNIT; HUMAN; HUMAN CELL; HYPERINSULINEMIA; PLACENTA DISORDER; PLACENTAL HYPERVASCULARIZATION; PREGNANCY DIABETES MELLITUS; PRIORITY JOURNAL; PROANGIOGENIC EFFECT; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ACTINS; CELL CYCLE; CELL PROLIFERATION; DIABETES MELLITUS, TYPE 2; ENDOTHELIAL CELLS; FEMALE; GLYCOGEN SYNTHASE KINASE 3; HUMANS; HYPERINSULINISM; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; NEOVASCULARIZATION, PHYSIOLOGIC; NITRIC OXIDE SYNTHASE TYPE III; PHOSPHORYLATION; PLACENTA; PREGNANCY; PROTO-ONCOGENE PROTEINS C-AKT; RAC1 GTP-BINDING PROTEIN; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION;

EID: 84883686535     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2013-1210     Document Type: Article

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