메뉴 건너뛰기




Volumn 4, Issue 1, 2013, Pages 5-12

Treatment with N-acetylcysteine does not alter blood glucose levels and the oxidative stress status in diabetic rats

Author keywords

Blood; butyrylcholinesterase; diabetes; N acetylcysteine; oxidative stress; rats

Indexed keywords

ACETYLCYSTEINE; ALANINE AMINOTRANSFERASE; ALLOXAN; ASPARTATE AMINOTRANSFERASE; BIOLOGICAL MARKER; CATALASE; CHOLINESTERASE; CREATININE; GAMMA GLUTAMYLTRANSFERASE; GLUCOSE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HEMOGLOBIN; HEMOGLOBIN A1C; MALONALDEHYDE; SODIUM CHLORIDE; SUPEROXIDE DISMUTASE; UREA;

EID: 84883673803     PISSN: 09769234     EISSN: 22297723     Source Type: Journal    
DOI: 10.4103/0976-9234.116755     Document Type: Article
Times cited : (3)

References (45)
  • 1
    • 0034079862 scopus 로고    scopus 로고
    • Free radicals and antioxidants in the year 2000
    • Halliwell B, Gutteridge JC. Free radicals and antioxidants in the year 2000. Ann N Y Acad Sci 2000;899:136-47.
    • (2000) Ann N y Acad Sci , vol.899 , pp. 136-147
    • Halliwell, B.1    Gutteridge, J.C.2
  • 2
    • 33645765312 scopus 로고    scopus 로고
    • Diabetes and mitochondrial function: Role of hyperglycemia and oxidative stress
    • Rolo AP, Palmeira CM. Diabetes and mitochondrial function: Role of hyperglycemia and oxidative stress. Toxicol Appl Pharmacol 2006;212:167-78.
    • (2006) Toxicol Appl Pharmacol , vol.212 , pp. 167-178
    • Rolo, A.P.1    Palmeira, C.M.2
  • 4
    • 33748946051 scopus 로고    scopus 로고
    • Treatment of patients with non-alcoholic fatty liver disease: Current views and perspectives
    • Federico A, Trappoliere M, Loguercio C. Treatment of patients with non-alcoholic fatty liver disease: Current views and perspectives. Dig Liver Dis 2006;38:789-01.
    • (2006) Dig Liver Dis , vol.38 , pp. 789-711
    • Federico, A.1    Trappoliere, M.2    Loguercio, C.3
  • 5
    • 33845876929 scopus 로고    scopus 로고
    • Elevated serum alanine transaminase in patients with type 1 or type 2 diabetes mellitus
    • DOI 10.1093/qjmed/hcl116
    • West J, Brousil J, Gazis A, Jackson L, Mansell P, Bennett A, et al. Elevated serum alanine transaminase in patients with type 1 or type 2 diabetes mellitus. Q J Med 2006;99:871-6. (Pubitemid 46024098)
    • (2006) QJM , vol.99 , Issue.12 , pp. 871-876
    • West, J.1    Brousil, J.2    Gazis, A.3    Jackson, L.4    Mansell, P.5    Bennett, A.6    Aithal, G.P.7
  • 6
    • 34447633921 scopus 로고    scopus 로고
    • Vitamin E ameliorates some biochemical parameters in normal and diabetic rats
    • DOI 10.1196/annals.1372.033, Diabetes Mellitus and Its Complications: Molecular Mechanisms, Epidemiology, and Clinical Medicine
    • Al-Shamsi M, Amin A, Adeghate E. Vitamin E ameliorates some biochemical parameters in normal and diabetic rats. Ann N Y Acad Sci 2006;1084:411-31. (Pubitemid 47091966)
    • (2006) Annals of the New York Academy of Sciences , vol.1084 , pp. 411-431
    • Al Shamsi, M.1    Amin, A.2    Adeghate, E.3
  • 7
    • 0036802875 scopus 로고    scopus 로고
    • Effect of alloxan-induced diabetes on serum and cardiac butyrylcholinesterases in the rat
    • DOI 10.1677/joe.0.1750241
    • Dave KR, Katyare SS. Effect of alloxan-induced diabetes on serum and cardiac butyrylcholinesterase in the rat. J Endocrinol 2002;175:241-50. (Pubitemid 35276603)
    • (2002) Journal of Endocrinology , vol.175 , Issue.1 , pp. 241-250
    • Dave, K.R.1    Katyare, S.S.2
  • 10
    • 34147095113 scopus 로고    scopus 로고
    • Downregulation of NADPH oxidase, antioxidant enzymes, and inflammatory markers in the heart of streptozotocin-induced diabetic rats by N-acetyl-L-cysteine
    • DOI 10.1152/ajpheart.01328.2005
    • Guo Z, Xia Z, Jiang J, McNeill J. Downregulation of NADPH oxidase, antioxidant enzymes and inflammatory markers in the heart of streptozotocin-induced diabetics rats by N-acetyl-L-cysteine. Am J Physiol Heart Circ Physiol 2007;292:H1728-36. (Pubitemid 46572395)
    • (2007) American Journal of Physiology - Heart and Circulatory Physiology , vol.292 , Issue.4
    • Guo, Z.1    Xia, Z.2    Jiang, J.3    McNeill, J.H.4
  • 11
    • 0033499583 scopus 로고    scopus 로고
    • Beneficial effects of antioxidants in diabetes: Possible protection of pancreatic b-cells against glucose toxicity
    • Kaneto H, Kajimoto Y, Miyagawa JI, Matsuoka TA, Fujitani Y, Yutaka U, et al. Beneficial effects of antioxidants in diabetes: Possible protection of pancreatic b-cells against glucose toxicity. Diabetes 1999;48:2398-06.
    • (1999) Diabetes , vol.48 , pp. 2398-2316
    • Kaneto, H.1    Kajimoto, Y.2    Miyagawa, J.I.3    Matsuoka, T.A.4    Fujitani, Y.5    Yutaka, U.6
  • 13
    • 0037315164 scopus 로고    scopus 로고
    • Comparative trial of N-acetyl-cysteine, taurine, and oxerutin on skin and kidney damage in long-term experimental diabetes
    • Odetti P, Pesce C, Traverso N, Menini S, Maineri EP, Cosso L, et al. Comparative trial of N-acetyl-cysteine, taurine, and oxerutin on skin and kidney damage in long-term experimental diabetes. Diabetes 2003;2:499-05.
    • (2003) Diabetes , vol.2 , pp. 499-415
    • Odetti, P.1    Pesce, C.2    Traverso, N.3    Menini, S.4    Maineri, E.P.5    Cosso, L.6
  • 14
    • 0024394697 scopus 로고
    • The antioxidant action of N-acetylcysteine: Its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid
    • DOI 10.1016/0891-5849(89)90066-X
    • Aruoma OI, Halliwell B, Hoey BM, Butler J. The antioxidant action of N-acetylcysteine: Its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid. Free Radic Biol Med 1989;6:593-7. (Pubitemid 19147809)
    • (1989) Free Radical Biology and Medicine , vol.6 , Issue.6 , pp. 593-597
    • Aruoma, O.I.1    Halliwell, B.2    Hoey, B.M.3    Butler, J.4
  • 15
    • 33646114733 scopus 로고    scopus 로고
    • Acetylcysteine in Diabetes (AID): A randomized study of acetylcysteine for the prevention of contrast nephropathy in diabetics
    • Coyle LC, Rodriguez A, Jeschke RE, Simon-Lee A, Abbott KC, Taylor AJ. Acetylcysteine in Diabetes (AID): A randomized study of acetylcysteine for the prevention of contrast nephropathy in diabetics. Am Heart J 2006;151:1032.e9-12.
    • (2006) Am Heart J , vol.151
    • Coyle, L.C.1    Rodriguez, A.2    Jeschke, R.E.3    Simon-Lee, A.4    Abbott, K.C.5    Taylor, A.J.6
  • 16
    • 69149098551 scopus 로고    scopus 로고
    • N-acetylcysteine: Multiple clinical applications
    • Millea PJ. N-acetylcysteine: Multiple clinical applications. Am Fam Physician 2009;80:265-9.
    • (2009) Am Fam Physician , vol.80 , pp. 265-269
    • Millea, P.J.1
  • 19
    • 37549029242 scopus 로고    scopus 로고
    • The mechanisms of alloxan- and streptozotocin-induced diabetes
    • Lenzen S. The mechanisms of alloxan- and streptozotocin-induced diabetes. Diabetologia 2008;51:216-26.
    • (2008) Diabetologia , vol.51 , pp. 216-226
    • Lenzen, S.1
  • 22
    • 0017184389 scopus 로고
    • A rapid and sensitive method for quantification of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM. A rapid and sensitive method for quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72:248-54.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 23
    • 0021318441 scopus 로고
    • Catalase in vitro
    • Aebi H. Catalase in vitro. Methods Enzymol 1984;105:121-6.
    • (1984) Methods Enzymol , vol.105 , pp. 121-126
    • Aebi, H.1
  • 24
    • 0019740344 scopus 로고
    • Glutathione peroxidase
    • Wendel A. Glutathione peroxidase. Methods Enzymol 1981;77:325-33.
    • (1981) Methods Enzymol , vol.77 , pp. 325-333
    • Wendel, A.1
  • 26
    • 33845649880 scopus 로고    scopus 로고
    • Rapid quantification of malondialdehyde in plasma by high performance liquid chromatography- visible detection
    • Grotto D, Santa Maria LD, Boeira S, Valentini J, Charão MF, Moro AM, et al. Rapid quantification of malondialdehyde in plasma by high performance liquid chromatography- visible detection. J Pharm Biomed Anal 2006;43:619-24.
    • (2006) J Pharm Biomed Anal , vol.43 , pp. 619-624
    • Grotto, D.1    Santa Maria, L.D.2    Boeira, S.3    Valentini, J.4    Charão, M.F.5    Moro, A.M.6
  • 27
    • 0014691273 scopus 로고
    • The utility of superoxide dismutase in studying free radical reactions. I. Radicals generated by the interaction of sulfite, dimethyl sulfoxide, and oxygen
    • McCord JM, Fridovich I. The utility of superoxide dismutase in studying free radical reactions. I. Radicals generated by the interaction of sulfite, dimethyl sulfoxide, and oxygen. J Biol Chem 1969;244:6056-63.
    • (1969) J Biol Chem , vol.244 , pp. 6056-6063
    • McCord, J.M.1    Fridovich, I.2
  • 28
    • 56649092631 scopus 로고    scopus 로고
    • Poorly controlled type 1 diabetes is associated with altered glutathione homeostasis in adolescents: Apparent resistence to N-acetylcysteine supplementation
    • Darmaun D, Smith SD, Sweeten S, Hartman BK, Welch S, Mauras N. Poorly controlled type 1 diabetes is associated with altered glutathione homeostasis in adolescents: Apparent resistence to N-acetylcysteine supplementation. Pediatr Diab 2008;9;577-82.
    • (2008) Pediatr Diab , vol.9 , pp. 577-582
    • Darmaun, D.1    Smith, S.D.2    Sweeten, S.3    Hartman, B.K.4    Welch, S.5    Mauras, N.6
  • 30
    • 0024456941 scopus 로고
    • Generation of free radicals by alloxan in the presence of bovine serum albumin: A role of protein sulfhydryl groups in alloxan cytotoxicity
    • Sakurai K, Miura T. Generation of free radicals by alloxan in the presence of bovine serum albumin: A role of protein sulfhydryl groups in alloxan cytotoxicity. Biochem Int 1989;19:405-12. (Pubitemid 19216497)
    • (1989) Biochemistry International , vol.19 , Issue.2 , pp. 405-412
    • Sakurai, K.1    Miura, T.2
  • 31
    • 33750721631 scopus 로고    scopus 로고
    • Clinical oxidation parameters of aging
    • DOI 10.1080/10715760600953859, PII N7461756537P2424, Free Radicals in the Aging Process - The 'Free Radical Theory of Aging' 50 years after -
    • Voss P, Siems W. Clinical oxidation parameters of aging. Free Radic Res 2006;40:1339-49. (Pubitemid 44698283)
    • (2006) Free Radical Research , vol.40 , Issue.12 , pp. 1339-1349
    • Voss, P.1    Siems, W.2
  • 32
    • 70349503662 scopus 로고    scopus 로고
    • N-acetylcysteine is able to reduce the oxidation status and the endothelial activation after a high-glucose content meal in patients with Type 2 diabetes mellitus
    • Masha A, Brocato L, Dinatale S, Mascia C, Biasi F, Martina V. N-acetylcysteine is able to reduce the oxidation status and the endothelial activation after a high-glucose content meal in patients with Type 2 diabetes mellitus. J Endocrinol Invest 2009;32:352-6.
    • (2009) J Endocrinol Invest , vol.32 , pp. 352-356
    • Masha, A.1    Brocato, L.2    Dinatale, S.3    Mascia, C.4    Biasi, F.5    Martina, V.6
  • 33
    • 34547813210 scopus 로고    scopus 로고
    • Evaluation of oxidative stress in insulin dependent diabetes mellitus (IDDM) patients
    • Ramakrishna V, Jailkhani R. Evaluation of oxidative stress in insulin dependent diabetes mellitus (IDDM) patients. Diagn Pathol 2007;2:22.
    • (2007) Diagn Pathol , vol.2 , pp. 22
    • Ramakrishna, V.1    Jailkhani, R.2
  • 35
    • 71649086882 scopus 로고    scopus 로고
    • N-acetylcysteine inhibits hyperglycemia-induced oxidative stress and apoptosis markers in diabetic neuropathy
    • Kamboj SS, Vasishta RK, Sandhir R. N-acetylcysteine inhibits hyperglycemia-induced oxidative stress and apoptosis markers in diabetic neuropathy. J Neurochem 2010;112:77-91.
    • (2010) J Neurochem , vol.112 , pp. 77-91
    • Kamboj, S.S.1    Vasishta, R.K.2    Sandhir, R.3
  • 36
    • 0032865515 scopus 로고    scopus 로고
    • Reactivity of biologically important thiol compounds with superoxide and hydrogen peroxide
    • DOI 10.1016/S0891-5849(99)00051-9, PII S0891584999000519
    • Winterbourn CC, Metodiewa D. Reactivity of biologically important compounds with superoxide and hydrogen peroxide. Free Radic Biol Med 1999;27:322-8. (Pubitemid 29395424)
    • (1999) Free Radical Biology and Medicine , vol.27 , Issue.3-4 , pp. 322-328
    • Winterbourn, C.C.1    Metodiewa, D.2
  • 37
    • 84863115387 scopus 로고    scopus 로고
    • Catalase deficiency accelerates diabetic renal injury through peroxisomal dysfunction
    • Hwang I, Lee J, Huh JY, Park J, Lee HB, Ho YS, et al. Catalase deficiency accelerates diabetic renal injury through peroxisomal dysfunction. Diabetes 2012;61:728-38.
    • (2012) Diabetes , vol.61 , pp. 728-738
    • Hwang, I.1    Lee, J.2    Huh, J.Y.3    Park, J.4    Lee, H.B.5    Ho, Y.S.6
  • 38
    • 15844413589 scopus 로고    scopus 로고
    • Long exposure to high glucose concentration impairs the responsive expression of γ-glutamylcysteine synthetase by interleukin-1β and tumor necrosis factor-α in mouse endothelial cells
    • DOI 10.1074/jbc.271.25.15146
    • Urata Y, Yamamoto H, Goto S, Tsushima H, Akazawa S, Yamashita S, et al. Long exposure to high glucose concentration impairs the responsive expression of gamma-glutamylcysteine synthetase by interleukin-Ibeta and tumor necrosis factor-alpha in mouse endothelial cells. J Biol Chem 1996;271:15146-52. (Pubitemid 26194994)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.25 , pp. 15146-15152
    • Urata, Y.1    Yamamoto, H.2    Goto, S.3    Tsushima, H.4    Akazawa, S.5    Yamashita, S.6    Nagataki, S.7    Kondo, T.8
  • 43
    • 0030576641 scopus 로고    scopus 로고
    • Differential distribution of free and bound glutathione and cyst(e)ine in human blood
    • DOI 10.1016/0006-2952(96)00241-9
    • Mills BJ, Lang CA. Differential distribution of free and bound glutathione and cyst(e)ine in human blood. Biochem Pharmacol 1996;52:401-6. (Pubitemid 26233582)
    • (1996) Biochemical Pharmacology , vol.52 , Issue.3 , pp. 401-406
    • Mills, B.J.1    Lang, C.A.2
  • 44
    • 37249057800 scopus 로고    scopus 로고
    • Acetylcholinesterase and butyrylcholinesterase as possible markers of low-grade systemic inflammation
    • Das UN. Acetylcholinesterase and butyrylcholinesterase as possible markers of low-grade systemic inflammation. Med Sci Monit 2007;13:RA214-21. (Pubitemid 350272890)
    • (2007) Medical Science Monitor , vol.13 , Issue.12
    • Das, U.N.1
  • 45
    • 84858082210 scopus 로고    scopus 로고
    • Effect of N-acetylcysteine treatment on oxidative stress and inflammation after severe burn
    • Csontos C, Rezman B, Foldi V, Bogar L, Drenkovics L, Röth E, et al. Effect of N-acetylcysteine treatment on oxidative stress and inflammation after severe burn. Burns 2011;38:428-37.
    • (2011) Burns , vol.38 , pp. 428-437
    • Csontos, C.1    Rezman, B.2    Foldi, V.3    Bogar, L.4    Drenkovics, L.5    Röth, E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.