Airway fungal colonization compromises the immune system allowing bacterial pneumonia to prevail

Critical Care Medicine

Volumn 41, Issue 9, 2013, Pages

  Roux, Damien ^a,b,c   Gaudry, Stéphane ^a,b,c   Khoy Ear, Linda ^a,b   Aloulou, Meryem ^a,b   Phillips Houlbracq, Mathilde ^a,b   Bex, Julie ^a,b   Skurnik, David ^d   Denamur, Erick ^d   Monteiro, Renato C ^a,b,e   Dreyfuss, Didier ^a,b,c   Ricard, Jean Damien ^a,b,c  

^a INSERM   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c HÔPITAL LOUIS MOURIER   (France)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

^e BICHAT HOSPITAL   (France)

Author keywords

alveolar macrophages; bacterial pneumonia; Candida albicans; interferon gamma; phagocytosis; Pseudomonas aeruginosa

Indexed keywords

AMPHOTERICIN B; FLUCONAZOLE; GAMMA INTERFERON;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL PNEUMONIA; CANDIDA ALBICANS; CONTROLLED STUDY; CORRELATIONAL STUDY; ESCHERICHIA COLI; FUNGAL COLONIZATION; IMMUNE DEFICIENCY; IMMUNE RESPONSE; LUNG ALVEOLUS MACROPHAGE; LUNG CLEARANCE; MALE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PATHOGEN CLEARANCE; PHAGOCYTOSIS; PREVALENCE; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; PULMONARY CANDIDIASIS; RAT; STAPHYLOCOCCUS AUREUS;

ANIMALS; ANTIFUNGAL AGENTS; BRONCHI; CANDIDA ALBICANS; IMMUNITY, CELLULAR; INTERFERON-GAMMA; MACROPHAGES, ALVEOLAR; MALE; PHAGOCYTOSIS; PNEUMONIA, BACTERIAL; RATS; RATS, WISTAR;

EID: 84883618500     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e31828a25d6     Document Type: Article

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