Imaging of carrageenan-induced local inflammation and adjuvant-induced systemic arthritis with [11C]PBR28 PET

Nuclear Medicine and Biology

Volumn 40, Issue 7, 2013, Pages 906-911

  Shao, Xia ^a   Wang, Xueding ^a   English, Sean J ^a   Desmond, Timothy ^a   Sherman, Phillip S ^a   Quesada, Carole A ^a   Piert, Morand R ^a  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

11C PBR28; Carrageenan induced inflammation macrophages, RAW 264.7 cells; Systemic adjuvant arthritis; TSPO

Indexed keywords

BENZODIAZEPINE RECEPTOR; CARBON PBR 28 C 11; CARRAGEENAN; PBR 28; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ADJUVANT ARTHRITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG EXCRETION; DRUG UPTAKE; FEMALE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; ISOTOPE TRACING; MACROPHAGE ACTIVATION; MYCOBACTERIUM BUTYRICUM; NONHUMAN; PAW EDEMA; PILOT STUDY; PLASMA CONCENTRATION-TIME CURVE; POSITRON EMISSION TOMOGRAPHY; PROTEIN EXPRESSION; RADIOACTIVITY; RADIOISOTOPE DISTRIBUTION; RAT; RHEUMATOID ARTHRITIS;

CARRAGEENAN-INDUCED INFLAMMATION MACROPHAGES, RAW 264.7 CELLS; SYSTEMIC ADJUVANT ARTHRITIS; TSPO; [(11)C]PBR28;

ANIMALS; ARTHRITIS, EXPERIMENTAL; BIOLOGICAL TRANSPORT; CARRAGEENAN; FEMALE; INFLAMMATION; MACROPHAGES; POSITRON-EMISSION TOMOGRAPHY; PYRIMIDINES; RATS;

EID: 84883553434     PISSN: 09698051     EISSN: 18729614     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2013.06.008     Document Type: Article

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