Redox nanoparticle therapeutics to cancer - Increase in therapeutic effect of doxorubicin, suppressing its adverse effect

Journal of Controlled Release

Volumn 172, Issue 1, 2013, Pages 137-143

  Yoshitomi, Toru ^a   Ozaki, Yuki ^a   Thangavel, Sindhu ^a   Nagasaki, Yukio ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

Cancer chemotherapy; Doxorubicin; Nitroxide radical; pH responsive polymeric micelle; Reactive oxygen species; Transcriptional factor

Indexed keywords

CANCER CHEMOTHERAPY; DOXORUBICIN; NITROXIDE RADICALS; POLYMERIC MICELLE; REACTIVE OXYGEN SPECIES; TRANSCRIPTIONAL FACTORS;

CHEMOTHERAPY; MAMMALS; NANOPARTICLES; OXYGEN; PATHOLOGY; TUMORS;

DISEASES;

CREATINE KINASE; DOXORUBICIN; I KAPPA B; LACTATE DEHYDROGENASE; NANOPARTICLE; REACTIVE OXYGEN METABOLITE; RIBONUCLEOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CANCER CHEMOTHERAPY; CANCER GROWTH; CARDIOTOXICITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LYMPHATIC SYSTEM; MALE; MOUSE; NONHUMAN; PH; PRIORITY JOURNAL; TUMOR VOLUME;

CANCER CHEMOTHERAPY; DOXORUBICIN; NITROXIDE RADICAL; PH-RESPONSIVE POLYMERIC MICELLE; REACTIVE OXYGEN SPECIES; TRANSCRIPTIONAL FACTOR;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; DELAYED-ACTION PREPARATIONS; DOXORUBICIN; DRUG SYNERGISM; FREE RADICAL SCAVENGERS; HUMANS; INFLAMMATION; MICE; MICE, INBRED BALB C; NANOPARTICLES; NEOPLASMS; NF-KAPPA B; NITROGEN OXIDES; OXIDATION-REDUCTION; REACTIVE OXYGEN SPECIES;

EID: 84883545388     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2013.08.011     Document Type: Article

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