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Volumn 123, Issue 9, 2013, Pages 3766-3776

Mobilizing monocytes to cross-present circulating viral antigen in chronic infection

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; HEPATITIS B SURFACE ANTIGEN; MEMBRANE ANTIGEN; VIRUS ANTIGEN;

EID: 84883533046     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI66043     Document Type: Article
Times cited : (79)

References (53)
  • 2
    • 79956077563 scopus 로고    scopus 로고
    • T cell exhaustion
    • Wherry EJ. T cell exhaustion. Nat Immunol. 2011;12(6):492-499.
    • (2011) Nat Immunol , vol.12 , Issue.6 , pp. 492-499
    • Wherry, E.J.1
  • 3
    • 33645229491 scopus 로고    scopus 로고
    • Dendritic cells take up viral antigens but do not support the early steps of hepatitis B virus infection
    • Untergasser A, et al. Dendritic cells take up viral antigens but do not support the early steps of hepatitis B virus infection. Hepatology. 2006;43(3):539-547.
    • (2006) Hepatology , vol.43 , Issue.3 , pp. 539-547
    • Untergasser, A.1
  • 4
    • 0029091006 scopus 로고
    • Exogenous hepatitis B surface antigen particles processed by dendritic cells or macrophages prime murine MHC class I-restricted cytotoxic T lymphocytes in vivo
    • Bohm W, et al. Exogenous hepatitis B surface antigen particles processed by dendritic cells or macrophages prime murine MHC class I-restricted cytotoxic T lymphocytes in vivo. J Immunol. 1995;155(7):3313-3321.
    • (1995) J Immunol , vol.155 , Issue.7 , pp. 3313-3321
    • Bohm, W.1
  • 5
    • 0036232611 scopus 로고    scopus 로고
    • Dendritic cells pulsed with exogenous hepatitis B surface antigen particles efficiently present epitopes to MHC class I-restricted T cells
    • DOI 10.1002/1521-4141(200204)32:4<1099::AID-IMMU10
    • Stober D, Trobonjaca Z, Reimann J, Schirmbeck R. Dendritic cells pulsed with exogenous hepatitis B surface antigen particles efficiently present epitopes to MHC class I-restricted cytotoxic T cells. Eur J Immunol. 2002;32(4):1099-1108. (Pubitemid 34428826)
    • (2002) European Journal of Immunology , vol.32 , Issue.4 , pp. 1099-1108
    • Stober, D.1    Trobonjaca, Z.2    Reimann, J.3    Schirmbeck, R.4
  • 6
    • 0028850506 scopus 로고
    • Processing of exogenous heat-aggregated (denatured) and particulate (native) hepatitis B surface antigen for class I-restricted epitope presentation
    • Schirmbeck R, Bohm W, Melber K, Reimann J. Processing of exogenous heat-aggregated (denatured) and particulate (native) hepatitis B surface antigen for class I-restricted epitope presentation. J Immunol. 1995;155(10):4676-4684.
    • (1995) J Immunol , vol.155 , Issue.10 , pp. 4676-4684
    • Schirmbeck, R.1    Bohm, W.2    Melber, K.3    Reimann, J.4
  • 7
    • 0028965525 scopus 로고
    • Hepatitis B virus small surface antigen particles are processed in a novel endosomal pathway for major histocompatibility complex class I-restricted epitope presentation
    • Schirmbeck R, Melber K, Reimann J. Hepatitis B virus small surface antigen particles are processed in a novel endosomal pathway for major histocompatibility complex class I-restricted epitope presentation. Eur J Immunol. 1995;25(4):1063-1070.
    • (1995) Eur J Immunol , vol.25 , Issue.4 , pp. 1063-1070
    • Schirmbeck, R.1    Melber, K.2    Reimann, J.3
  • 8
    • 0025276235 scopus 로고
    • Selective killing of hepatitis B envelope antigen-specific B cells by class I-restricted, exogenous antigen-specific T lymphocytes
    • Barnaba V, Franco A, Alberti A, Benvenuto R, Balsano F. Selective killing of hepatitis B envelope antigen-specific B cells by class I-restricted, exogenous antigen-specific T lymphocytes. Nature. 1990;345(6272):258-260.
    • (1990) Nature , vol.345 , Issue.6272 , pp. 258-260
    • Barnaba, V.1    Franco, A.2    Alberti, A.3    Benvenuto, R.4    Balsano, F.5
  • 12
    • 79958840661 scopus 로고    scopus 로고
    • Engineering virus-specific T cells that target HBV infected hepatocytes and hepatocellular carcinoma cell lines
    • Gehring AJ, et al. Engineering virus-specific T cells that target HBV infected hepatocytes and hepatocellular carcinoma cell lines. J Hepatol. 2011;55(1):103-110.
    • (2011) J Hepatol , vol.55 , Issue.1 , pp. 103-110
    • Gehring, A.J.1
  • 15
    • 77953522371 scopus 로고    scopus 로고
    • Superior antigen cross-presentation and XCR1 expression define human CD11c+CD141+ cells as homologues of mouse CD8+ dendritic cells
    • Bachem A, et al. Superior antigen cross-presentation and XCR1 expression define human CD11c+CD141+ cells as homologues of mouse CD8+ dendritic cells. J Exp Med. 2010;207(6):1273-1281.
    • (2010) J Exp Med , vol.207 , Issue.6 , pp. 1273-1281
    • Bachem, A.1
  • 16
    • 77953502765 scopus 로고    scopus 로고
    • Human CD141+ (BDCA-3)+ dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens
    • Jongbloed SL, et al. Human CD141+ (BDCA-3)+ dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens. J Exp Med. 2010;207(6):1247-1260.
    • (2010) J Exp Med , vol.207 , Issue.6 , pp. 1247-1260
    • Jongbloed, S.L.1
  • 17
    • 77953484184 scopus 로고    scopus 로고
    • Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8alpha+ dendritic cells
    • Poulin LF, et al. Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8alpha+ dendritic cells. J Exp Med. 2010;207(6):1261-1271.
    • (2010) J Exp Med , vol.207 , Issue.6 , pp. 1261-1271
    • Poulin, L.F.1
  • 18
    • 84864293006 scopus 로고    scopus 로고
    • Human tissues contain CD141(hi) cross-presenting dendritic cells with functional homology to mouse CD103(+) nonlymphoid dendritic cells
    • Haniffa M, et al. Human tissues contain CD141(hi) cross-presenting dendritic cells with functional homology to mouse CD103(+) nonlymphoid dendritic cells. Immunity. 2012;37(1):60-73.
    • (2012) Immunity , vol.37 , Issue.1 , pp. 60-73
    • Haniffa, M.1
  • 19
    • 55549116694 scopus 로고    scopus 로고
    • Host ethnicity and virus genotype shape the hepatitis B virus-specific T-cell repertoire
    • Tan AT, et al. Host ethnicity and virus genotype shape the hepatitis B virus-specific T-cell repertoire. J Virol. 2008;82(22):10986-10997.
    • (2008) J Virol , vol.82 , Issue.22 , pp. 10986-10997
    • Tan, A.T.1
  • 20
    • 84865504614 scopus 로고    scopus 로고
    • Preserved T-cell function in children and young adults with immune-tolerant chronic hepatitis B
    • Kennedy P, et al. Preserved T-cell function in children and young adults with immune-tolerant chronic hepatitis B. Gastroenterology. 2012;143(3):637-645.
    • (2012) Gastroenterology , vol.143 , Issue.3 , pp. 637-645
    • Kennedy, P.1
  • 21
    • 84866705034 scopus 로고    scopus 로고
    • Restored function of HBV-specific T cells after long-term effective therapy with nucleos(t)ide analogues
    • Boni C, et al. Restored function of HBV-specific T cells after long-term effective therapy with nucleos(t)ide analogues. Gastroenterology. 2012;143(4):e963-e969.
    • (2012) Gastroenterology , vol.143 , Issue.4
    • Boni, C.1
  • 24
    • 79955112364 scopus 로고    scopus 로고
    • Role of the coinhibitory receptor cytotoxic T lymphocyte antigen-4 on apoptosis-Prone CD8 T cells in persistent hepatitis B virus infection
    • Schurich A, et al. Role of the coinhibitory receptor cytotoxic T lymphocyte antigen-4 on apoptosis-Prone CD8 T cells in persistent hepatitis B virus infection. Hepatology. 2011;53(5):1494-1503.
    • (2011) Hepatology , vol.53 , Issue.5 , pp. 1494-1503
    • Schurich, A.1
  • 25
    • 0035476477 scopus 로고    scopus 로고
    • Interleukin 15 skews monocyte differentiation into dendritic cells with features of Langerhans cells
    • Mohamadzadeh M, et al. Interleukin 15 skews monocyte differentiation into dendritic cells with features of Langerhans cells. J Exp Med. 2001;194(7):1013-1020.
    • (2001) J Exp Med , vol.194 , Issue.7 , pp. 1013-1020
    • Mohamadzadeh, M.1
  • 27
    • 0043204311 scopus 로고    scopus 로고
    • Hepatitis B virus-induced defect of monocyte-derived dendritic cells leads to impaired T helper type 1 response in vitro: Mechanisms for viral immune escape
    • DOI 10.1046/j.1365-2567.2003.01699.x
    • Beckebaum S, et al. Hepatitis B virus-induced defect of monocyte-derived dendritic cells leads to impaired T helper type 1 response in vitro: mechanisms for viral immune escape. Immunology. 2003;109(4):487-495. (Pubitemid 36930163)
    • (2003) Immunology , vol.109 , Issue.4 , pp. 487-495
    • Beckebaum, S.1    Cicinnati, V.R.2    Zhang, X.3    Ferencik, S.4    Frilling, A.5    Grosse-Wilde, H.6    Broelsch, C.E.7    Gerken, G.8
  • 28
    • 58149299723 scopus 로고    scopus 로고
    • Hepatitis B virus surface antigen impairs myeloid dendritic cell function: A possible immune escape mechanism of hepatitis B virus
    • Op den Brouw ML, et al. Hepatitis B virus surface antigen impairs myeloid dendritic cell function: a possible immune escape mechanism of hepatitis B virus. Immunology. 2009;126(2):280-289.
    • (2009) Immunology , vol.126 , Issue.2 , pp. 280-289
    • Op Den Brouw, M.L.1
  • 29
    • 0032211129 scopus 로고    scopus 로고
    • Dendritic cell immunization breaks cytotoxic T lymphocyte tolerance in hepatitis B virus transgenic mice
    • Shimizu Y, Guidotti LG, Fowler P, Chisari FV. Dendritic cell immunization breaks cytotoxic T lymphocyte tolerance in hepatitis B virus transgenic mice. J Immunol. 1998;161(9):4520-4529. (Pubitemid 28492022)
    • (1998) Journal of Immunology , vol.161 , Issue.9 , pp. 4520-4529
    • Shimizu, Y.1    Guidotti, L.G.2    Fowler, P.3    Chisari, F.V.4
  • 31
    • 33750610311 scopus 로고    scopus 로고
    • Favorable effect of adefovir on the number and functionality of myeloid dendritic cells of patients with chronic HBV
    • DOI 10.1002/hep.21340
    • van der Molen RG, Sprengers D, Biesta PJ, Kusters JG, Janssen HL. Favorable effect of adefovir on the number and functionality of myeloid dendritic cells of patients with chronic HBV. Hepatology. 2006;44(4):907-914. (Pubitemid 46489555)
    • (2006) Hepatology , vol.44 , Issue.4 , pp. 907-914
    • Van Der, M.R.G.1    Sprengers, D.2    Biesta, P.J.3    Kusters, J.G.4    Janssen, H.L.A.5
  • 32
    • 4544245140 scopus 로고    scopus 로고
    • Functional impairment of myeloid and plasmacytoid dendritic cells of patients with chronic hepatitis B
    • van der Molen RG, et al. Functional impairment of myeloid and plasmacytoid dendritic cells of patients with chronic hepatitis B. Hepatology. 2004;40(3):738-746.
    • (2004) Hepatology , vol.40 , Issue.3 , pp. 738-746
    • Van Der Molen, R.G.1
  • 33
    • 79251543296 scopus 로고    scopus 로고
    • Hepatitis B virus lacks immune activating capacity, but actively inhibits plasmacytoid dendritic cell function
    • Woltman AM, Op den Brouw ML, Biesta PJ, Shi CC, Janssen HL. Hepatitis B virus lacks immune activating capacity, but actively inhibits plasmacytoid dendritic cell function. PLoS One. 2011;6(1):e15324.
    • (2011) PLoS One , vol.6 , Issue.1
    • Woltman, A.M.1    Op Den Brouw, M.L.2    Biesta, P.J.3    Shi, C.C.4    Janssen, H.L.5
  • 34
    • 64749099759 scopus 로고    scopus 로고
    • Patients with chronic hepatitis B infection display deficiency of plasmacytoid dendritic cells with reduced expression of TLR9
    • Xie Q, et al. Patients with chronic hepatitis B infection display deficiency of plasmacytoid dendritic cells with reduced expression of TLR9. Microbes Infect. 2009;11(4):515-523.
    • (2009) Microbes Infect , vol.11 , Issue.4 , pp. 515-523
    • Xie, Q.1
  • 35
    • 65449117568 scopus 로고    scopus 로고
    • Hepatitis B virus suppresses toll-like receptor-mediated innate immune responses in murine parenchymal and nonparenchymal liver cells
    • Wu J, et al. Hepatitis B virus suppresses toll-like receptor-mediated innate immune responses in murine parenchymal and nonparenchymal liver cells. Hepatology. 2009;49(4):1132-1140.
    • (2009) Hepatology , vol.49 , Issue.4 , pp. 1132-1140
    • Wu, J.1
  • 36
    • 4944245002 scopus 로고    scopus 로고
    • The site of primary T cell activation is a determinant of the balance between intrahepatic tolerance and immunity
    • DOI 10.1172/JCI200421593
    • Bowen DG, Zen M, Holz L, Davis T, McCaughan GW, Bertolino P. The site of primary T cell activation is a determinant of the balance between intrahepatic tolerance and immunity. J Clin Invest. 2004;114(5):701-712. (Pubitemid 39578761)
    • (2004) Journal of Clinical Investigation , vol.114 , Issue.5 , pp. 701-712
    • Bowen, D.G.1    Zen, M.2    Holz, L.3    Davis, T.4    McCaughan, G.W.5    Bertolino, P.6
  • 37
    • 80053309337 scopus 로고    scopus 로고
    • Cross-presentation of antigen by diverse subsets of murine liver cells
    • Ebrahimkhani MR, Mohar I, Crispe IN. Cross-presentation of antigen by diverse subsets of murine liver cells. Hepatology. 2011;54(4):1379-1387.
    • (2011) Hepatology , vol.54 , Issue.4 , pp. 1379-1387
    • Ebrahimkhani, M.R.1    Mohar, I.2    Crispe, I.N.3
  • 39
    • 84859341989 scopus 로고    scopus 로고
    • Viral infection triggers rapid differentiation of human blood monocytes into dendritic cells
    • Hou W, et al. Viral infection triggers rapid differentiation of human blood monocytes into dendritic cells. Blood. 2012;119(13):3128-3131.
    • (2012) Blood , vol.119 , Issue.13 , pp. 3128-3131
    • Hou, W.1
  • 40
    • 33645088198 scopus 로고    scopus 로고
    • Immature monocytes acquire antigens from other cells in the bone marrow and present them to T cells after maturing in the periphery
    • Tacke F, Ginhoux F, Jakubzick C, van Rooijen N, Merad M, Randolph GJ. Immature monocytes acquire antigens from other cells in the bone marrow and present them to T cells after maturing in the periphery. J Exp Med. 2006;203(3):583-597.
    • (2006) J Exp Med , vol.203 , Issue.3 , pp. 583-597
    • Tacke, F.1    Ginhoux, F.2    Jakubzick, C.3    Van Rooijen, N.4    Merad, M.5    Randolph, G.J.6
  • 42
    • 51049123791 scopus 로고    scopus 로고
    • Functional skewing of the global CD8 T cell population in chronic hepatitis B virus infection
    • Das A, et al. Functional skewing of the global CD8 T cell population in chronic hepatitis B virus infection. J Exp Med. 2008;205(9):2111-2124.
    • (2008) J Exp Med , vol.205 , Issue.9 , pp. 2111-2124
    • Das, A.1
  • 45
    • 84866178367 scopus 로고    scopus 로고
    • Internalization and endosomal degradation of receptor-bound antigens regulate the efficiency of cross presentation by human dendritic cells
    • Chatterjee B, et al. Internalization and endosomal degradation of receptor-bound antigens regulate the efficiency of cross presentation by human dendritic cells. Blood. 2012;120(10):2011-2020.
    • (2012) Blood , vol.120 , Issue.10 , pp. 2011-2020
    • Chatterjee, B.1
  • 46
    • 14844340568 scopus 로고    scopus 로고
    • Differential lysosomal proteolysis in antigen-presenting cells determines antigen fate
    • DOI 10.1126/science.1108003
    • Delamarre L, Pack M, Chang H, Mellman I, Trombetta ES. Differential lysosomal proteolysis in antigen-presenting cells determines antigen fate. Science. 2005;307(5715):1630-1634. (Pubitemid 40354746)
    • (2005) Science , vol.307 , Issue.5715 , pp. 1630-1634
    • Delamarre, L.1    Pack, M.2    Chang, H.3    Mellman, I.4    Trombetta, E.S.5
  • 47
    • 61749093304 scopus 로고    scopus 로고
    • In vitro use of autologous dendritic cells improves detection of T cell responses to hepatitis B virus (HBV) antigens
    • Carotenuto P, Artsen A, Niesters HG, Osterhaus AD, Pontesilli O. In vitro use of autologous dendritic cells improves detection of T cell responses to hepatitis B virus (HBV) antigens. J Med Virol. 2009;81(2):332-339.
    • (2009) J Med Virol , vol.81 , Issue.2 , pp. 332-339
    • Carotenuto, P.1    Artsen, A.2    Niesters, H.G.3    Osterhaus, A.D.4    Pontesilli, O.5
  • 48
    • 33846241276 scopus 로고    scopus 로고
    • Hepatitis B virus (HBV) antigen-pulsed monocyte-derived dendritic cells from HBV-associated hepatocellular carcinoma patients significantly enhance specific T cell responses in vitro
    • DOI 10.1111/j.1365-2249.2006.03281.x
    • Shi M, et al. Hepatitis B virus (HBV) antigen-pulsed monocyte-derived dendritic cells from HBV-associated hepatocellular carcinoma patients significantly enhance specific T cell responses in vitro. Clin Exp Immunol. 2007;147(2):277-286. (Pubitemid 46096006)
    • (2007) Clinical and Experimental Immunology , vol.147 , Issue.2 , pp. 277-286
    • Shi, M.1    Qian, S.2    Chen, W.-W.3    Zhang, H.4    Zhang, B.5    Tang, Z.-R.6    Zhang, Z.7    Wang, F.-S.8
  • 49
    • 77957756030 scopus 로고    scopus 로고
    • A phase I clinical trial of dendritic cell immunotherapy in HCV-infected individuals
    • Gowans EJ, et al. A phase I clinical trial of dendritic cell immunotherapy in HCV-infected individuals. J Hepatol. 2010;53(4):599-607.
    • (2010) J Hepatol , vol.53 , Issue.4 , pp. 599-607
    • Gowans, E.J.1
  • 50
    • 0035043482 scopus 로고    scopus 로고
    • + T cells from late-stage patients on prolonged antiretroviral therapy by stimulation in vitro with HIV-1 protein-loaded dendritic cells
    • DOI 10.1128/JVI.75.9.4413-4419.2001
    • Fan Z, Huang XL, Borowski L, Mellors JW, Rinaldo CR. Restoration of anti-human immunodeficiency virus type 1 (HIV-1) responses in CD8+ T cells from late-stage patients on prolonged antiretroviral therapy by stimulation in vitro with HIV-1 protein-loaded dendritic cells. J Virol. 2001;75(9):4413-4419. (Pubitemid 32410155)
    • (2001) Journal of Virology , vol.75 , Issue.9 , pp. 4413-4419
    • Fan, Z.1    Huang, X.-L.2    Borowski, L.3    Mellors, J.W.4    Rinaldo Jr., C.R.5
  • 51
    • 0034858032 scopus 로고    scopus 로고
    • + T cells expanded with inactivated-virus-pulsed dendritic cells
    • DOI 10.1128/JVI.75.19.8949-8956.2001
    • Lu W, Andrieu JM. In vitro human immunodeficiency virus eradication by autologous CD8(+) T cells expanded with inactivated-virus-pulsed dendritic cells. J Virol. 2001;75(19):8949-8956. (Pubitemid 32851899)
    • (2001) Journal of Virology , vol.75 , Issue.19 , pp. 8949-8956
    • Lu, W.1    Andrieu, J.-M.2
  • 53
    • 84883527854 scopus 로고    scopus 로고
    • Results of a phase III clinical trial with an HbsAg-HBIG Immunogenic complex therapeutic vaccine for chronic hepatitis B patients: Experiences and findings
    • In press
    • Xu D-Z, et al. Results of a phase III clinical trial with an HbsAg-HBIG Immunogenic complex therapeutic vaccine for chronic hepatitis B patients: experiences and findings. J Hepatol. In press.
    • J Hepatol
    • Xu, D.-Z.1


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