Microarray Profiling of Mononuclear Peripheral Blood Cells Identifies Novel Candidate Genes Related to Chemoradiation Response in Rectal Cancer

PLoS ONE

Volumn 8, Issue 9, 2013, Pages

  Palma, Pablo ^a   Cuadros, Marta ^b   Conde Muíño, Raquel ^a   Olmedo, Carmen ^a   Cano, Carlos ^b   Segura Jiménez, Inmaculada ^a   Blanco, Armando ^b   Bueno, Pablo ^a   Ferrón, J Antonio ^a   Medina, Pedro ^b  

^a HUVN   (Spain)

^b UNIVERSITY OF GRANADA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CAPECITABINE; COMPLEMENTARY DNA; COMPLEMENTARY RNA; OXALIPLATIN; TRISTETRAPROLIN;

ADULT; ADVANCED CANCER; AGED; ARTICLE; BC 035656.1 GENE; CANCER ADJUVANT THERAPY; CANCER PROGNOSIS; CANCER STAGING; CAPG GENE; CHEMORADIOTHERAPY; CIR GENE; CLINICAL ARTICLE; CONTROLLED STUDY; FALZ GENE; FEMALE; GENE; GENE EXPRESSION PROFILING; HLA DPB2 GENE; HUMAN; HUMAN CELL; MALE; MICROARRAY ANALYSIS; NUPL2 GENE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRDM2 GENE; REAL TIME POLYMERASE CHAIN REACTION; RECTUM ABDOMINOPERINEAL RESECTION; RECTUM ANTERIOR RESECTION; RECTUM CANCER; RNA EXTRACTION; TUMOR REGRESSION; ZFP36 GENE;

ADULT; AGED; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LEUKOCYTES, MONONUCLEAR; MALE; MIDDLE AGED; NEOPLASM STAGING; PROGNOSIS; RECTAL NEOPLASMS; REPRODUCIBILITY OF RESULTS; TREATMENT OUTCOME; TUMOR MARKERS, BIOLOGICAL;

EID: 84883513114     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0074034     Document Type: Article

References (34)

1. Sauer R, Becker H, Hohenberger W, (2004) Preoperative versus postoperative chemoradiotherapy for rectal cancer. N Engl J Med 351: 1731-1740.
2. Nelson H, Sargent DJ, (2001) Refining multimodal therapy for rectal cancer. N Engl J Med 345: 690-692.
3. Kapiteijn E, Marijnen CA, Nagtegaal ID, (2001) Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer. N Engl J Med 345: 638-646.
4. Janjan NA, Khoo VS, Abbruzzese J, (1999) Tumor downstaging and sphincter preservation with preoperative chemoradiation in locally advanced rectal cancer: The M.D. Anderson Cancer Center experience. Int J Radiat Oncol Biol Phys 44: 1027-1038.
5. Kim JS, Kim JS, Cho MJ, (2002) Preoperative chemoradiation using oral capecitabine in locally advanced rectal cancer. Int J Radiat Oncol Biol Phys 54: 403-408.
6. Glynne-Jones R, Harrison M, (2007) Locally advanced rectal cancer: What is the evidence for induction chemoradiation? Oncologist 12: 1309-1318.
7. Crane CH, Skibber JM, Feig BW, (2003) Response to preoperative chemoradiation increases the use of sphincter-preserving surgery in patients with locally advanced low rectal carcinoma. Cancer 97: 517-524.
8. Rodel C, Martus P, Papadoupolos T, (2005) Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer. J Clin Oncol 23: 8688-8696.
9. Valentini V, Coco C, Picciocchi A, (2002) Does downstaging predict improved outcome after preoperative chemoradiation for extraperitoneal locally advanced rectal cancer? A long-term analysis of 165 patients. Int J Radiat Oncol Biol Phys 53: 664-674.
10. Edwards CJ, Feldman JL, Beech J, Shields KM, Stover JA, (2007) Molecular profile of peripheral blood mononuclear cells from patients with rheumatoid arthritis. Mol Med 13: 40-58.
11. Bluth M, Lin Y, Zhang H, Viterbo D, Zenilman M, (2008) Gene expression profiles in cells of peripheral blood identify new molecular markers of acute pancreatitis. Arch Surg143: 227-234.
12. Twine NC, Stover JA, Marshall B, Dukart G, Hidalgo M, (2003) Disease-associated expression profiles in peripheral blood mononuclear cells from patients with advanced renal cell carcinoma. Cancer Res 63: 6069-6075.
13. Hedenfalk I, Duggan D, Chen Y, Radmacher M, Bittner M, (2001) Gene-expression profiles in hereditary breast cancer. N Engl J Med 344: 539-48.
14. Hu N, Wang C, Hu Y, Yang HH, Giffen C, (2005) Genome-wide association study in esophageal cancer using GeneChip mapping 10 K array. Cancer Res 65: 2542-2546.
15. Baine MJ, Chakraborty S, Smith LM, Mallya K, Sasson AR, et al. (2010) Transcriptional profiling of peripheral blood mononuclear cells in pancreatic cancer patients identifies novel genes with potential diagnostic utility. PLoS One6: e17014.
16. DePrimo SE, Wong LM, Khatry DB, Nicholas SL, Manning WC, et al. (2003) Expression profiling of blood samples from an SU5416 phase III metastatic colorectal cancer clinical trial: a novel strategy for biomarker identification. BMC Cancer 3: 1-12.
17. Tusher V, Tibshirani R, Chu C, (2001) Significance analysis of microarrays applied to ionising radiation response. Proc Nat Acad Sci USA 98: 5116-5121.
18. Barrett T, Troup D, Wilhite S, Ledoux P, Evangelista C, et al. (2011) NCBI GEO: Archive for functional genomics data sets 10 years on. Nucleic Acids Res 39(suppl 1): D1005.
19. Hansen CN, Ketabi Z, Rosenstierne MW, Palle C, Boesen HC, et al. (2009) Expression of CPEB, GAPDH and U6snRNA in cervical and ovarian tissue during cancer development. APMIS 117: 53-9.
20. Bandrés E, Malumbres R, Cubedo E, Honorato B, Zarate R, et al. (2007) A signature of 8 genes could identify the risk of recurrence and progression in Duke's B colon cancer patients. Oncology Reports 17: 1089-1094.
21. Ghadimi BM, Grade M, Difilippantonio MJ, Varma S, Simon R, et al. (2005) Effectiveness of gene expression profiling for response prediction of rectal adenocarcinomas to preoperative chemoradiotherapy. J Clin Oncol 23: 1826-1838.
22. Demaria S, Formenti SC, (2007) Sensors of ionizing radiation effects on the immunological microenvironment of cancer. Int J Radiat Biol 83: 819-825.
23. Lorimore SA, Coates PJ, Scobie GE, Milne G, Wright EG, (2001) Inflammatory-type responses after exposure to ionizing radiation in vivo: a mechanism for radiation-induced bystander effects? Oncogene 20: 7085-7095.
24. Apetoh L, Ghiringhelli F, Tesniere A, Obeid M, Ortiz C, et al. (2007) Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy. Nat Med 13: 1050-1059.
25. Nesslinger NJ, Sahota RA, Stone B, Johnson K, Chima N, et al. (2007) Standard treatments induce antigen-specific immune responses in prostate cancer. Clin Cancer Res 13: 1493-1502.
26. Schaue D, Comin-Anduix B, Ribas A, Zhang L, Goodglick L, et al. (2008) T-cell responses to survivin in cancer patients undergoing radiation therapy. Clin Cancer Res 14: 4883-4890.
27. Molling JW, Langius JA, Langendijk JA, Leemans R, Bontkes H, et al. (2007) Low levels of circulating invariant natutal killer T cells predict poor clinical outcome in patients with head and neck squamous cell carcinoma. J Clin Oncol 25: 862-868.
28. Kitayama J, Yasuda K, Kawai K, Sunami E, Nagawa H, (2011) Circulating lymphocyte is an important determinant of the effectiveness of preoperative radiotherapy in advanced rectal cancer. BMC Cancer 11: 64-72.
29. Ishiara S, Iinuma H, Fukushima Y, Akahane T, Horiuchi A, et al. (2012) Radiation-induced apoptosis of peripheral blood lymphocytes is correlated with histological regression of rectal cancer in response to preoperative chemotherapy. Ann Surg oncol 19: 1192-1198.
30. Te{ogonek}pkowski TM, Kruszewski MK, (2011) Molecular cross-talk between the NRF2/KEAP1, signaling pathway, autophagy, and apoptosis. Free Radic Biol Med 50: 1186-95.
31. Ciais D, Cherradi N, Bailly S, Grenier E, Berra E, (2004) Destabilization of vascular endothelial growth factor mRNA by the zinc-finger protein TIS11b. Oncogene 2004 23: 8673-8680.
32. Essafi-Benkhadir K, Ornesto C, Stebe E, Moroni C, Pagès G, (2007) Tristetraprolin inhibits Ras-dependent tumor vascularization by inducing vascular endothelial growth factor mRNA degradation. Mol Biol Cell 18: 4648-4658.
33. Vincenzi B, Santini D, Russo A, Gavasci M, Battistoni F, et al. (2007) Circulating VEGF reduction, response and outcome in advanced colorectal cancer patients treated with cetuximab plus irinotecan. Pharmacogenomics (8) (): 319-27.
34. Gerard JP, Azria D, Gourgou-Bourgade S, (2010) Comparison of two neoadjuvant chemotherapy regimens for locally advanced rectal cancer: Results of the phase III trial ACCORD 12/0405-Prodige 2. J Clin Oncol 28: 1638-1644.