Use of gene expression profiles in cells of peripheral blood to identify new molecular markers of acute pancreatitis

Archives of Surgery

Volumn 143, Issue 3, 2008, Pages 227-233

  Bluth, Martin ^a,b   Lin, Yin Yao ^a   Zhang, Hong ^a   Viterbo, Domenico ^a   Zenilman, Michael ^a  

^a SUNY DOWNSTATE MEDICAL CENTER   (United States)

^b SUNY Downstate Medical Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLECYSTOKININ RECEPTOR; COMPLEMENTARY RNA; GENOMIC DNA; GLUCOCORTICOID RECEPTOR; PHOSPHOLIPASE D1; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROSTAGLANDIN E RECEPTOR; SODIUM CHLORIDE; TAUROCHOLIC ACID; TRANSFORMING GROWTH FACTOR BETA;

ACUTE PANCREATITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BLOOD CHEMISTRY; COMPARATIVE STUDY; CONTROLLED STUDY; DNA MICROARRAY; EXPERIMENTAL MODEL; EXPERIMENTAL RAT; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; MALE; MICROARRAY ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; RAT; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; SEPSIS; SPRAGUE DAWLEY RAT;

ACUTE DISEASE; ANIMALS; BIOLOGICAL MARKERS; DISEASE MODELS, ANIMAL; GENE EXPRESSION PROFILING; LEUKOCYTES; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PANCREATITIS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 41149160784     PISSN: 00040010     EISSN: 15383644     Source Type: Journal    
DOI: 10.1001/archsurg.2007.73     Document Type: Article

References (38)

1. Baron TH, Morgan D. Acute necrotizing pancreatitis. N Engl J Med. 1999;340(18): 1412-1417.
2. Bradley EL. A clinically based classification system for acute pancreatitis: summary of the International Symposium on Acute Pancreatitis, Atlanta, Ga, September 11 through 13, 1992. Arch Surg. 1993;128(5):586-590.
3. Foitzik T, Lewandrowski KB, Fernández-del Castillo C, Rattner DW, Warshaw AL. Evidence for extraluminal trypsinogen activation in three different models of acute pancreatitis. Surgery. 1994;115(6):698-702.
4. Lerch MM, Hernández CA, Adler G. Gallstones and acute pancreatitis - mechanisms and mechanics. Dig Dis. 1994;12(4):242-247.
5. Senninger N, Moody FG, Coelho JC, Van Buren DH. The role of biliary obstruction in the pathogenesis of acute pancreatitis in the opossum. Surgery. 1986; 99(6):688-693.
6. Steer ML, Meldolesi J. The cell biology of experimental pancreatitis. N Engl J Med. 1987;316(3):144-150.
7. De Campos T, Deree J, Coimbra R. From acute pancreatitis to end-organ injury: mechanisms of acute lung injury. Surg Infect (Larchmt). 2007;8(1):107-120.
8. Zhang H, Patel SA, Kandil E, Mueller CM, Lin YY, Zenilman ME. Pancreatic elastase is proven to be a mannose-binding protein - implications for the systemic response to pancreatitis. Surgery. 2003;133(6):678-688.
9. Jaffray C, Mendez C, Denham W, Carter G, Norman J. Specific pancreatic enzymes activate macrophages to produce tumor necrosis factor-alpha: role of nuclear factor kappa B and inhibitory kappa B proteins. J Gastrointest Surg. 2000;4(4):370-377.
10. Jaffray C, Yang J, Carter G, Mendez C, Norman J. Pancreatic elastase activates pulmonary nuclear factor kappa B and inhibitory kappa B, mimicking pancreatitis-associated adult respiratory distress syndrome. Surgery. 2000;128(2):225-231.
11. Ranson JHC, Rifkind KM, Roses DF, Fink SD, Eng K, Spencer FC. Prognostic signs and the role of operative management in acute pancreatitis. Surg Gynecol Obstet. 1974;139(1):69-81.
12. Agarwal N, Pitchumoni CS. Assessment of severity in acute pancreatitis. Am J Gastroenterol. 1991;86(10):1385-1391.
13. Corfield AP, Cooper MJ, Williamson RCN, et al. Prediction of severity in acute pancreatitis: prospective comparison of three prognostic indices. Lancet. 1985; 2(8452):403-407.
14. Triester SL, Kowdley KV. Prognostic factors in acute pancreatitis. J Clin Gastroenterol. 2002;34(2):167-176.
15. Papachristou GI, Clermont G, Sharma A, Yadav D, Whitcomb DC. Risk and markers of severe acute pancreatitis. Gastroenterol Clin North Am. 2007;36(2):277-296.
16. Iovanna JL, Keim V, Nordback I, et al. Serum levels of pancreatitis-associated protein as indicators of the course of acute pancreatitis: Multicentric Study Group on Acute Pancreatitis. Gastroenterology. 1994;106(3):728-734.
17. Zenilman ME, Tuchman D, Zheng Q, Levine J, Delany H. Comparison of reg I and reg III levels during acute pancreatitis in the rat. Ann Surg. 2000;232(5):646-652.
18. Bluth MH, Kandil E, Mueller CM, et al. Sophorolipids block lethal effects of septic shock in rats in a cecal ligation and puncture model of experimental sepsis. Crit Care Med. 2006;34(1):188-195.
19. Bluth MH, Norowitz KB, Chice S, et al. IgE, CD8(+)CD60+ T cells and IFN-alpha in human immunity to parvovirus B19 in selective IgA deficiency. Hum Immunol. 2005;66(10):1029-1038.
20. Wodicka L, Dong H, Mittmann M, Ho MH, Lockhart DJ. Genome-wide expression monitoring in Saccharomyces cerevisiae. Nat Biotechnol. 1997;15(13): 1359-1367.
21. Zhang H, Kandil E, Lin YY, Levi G, Zenilman ME. Targeted inhibition of gene expression of pancreatitis-associated proteins exacerbates the severity of acute pancreatitis in rats. Scand J Gastroenterol. 2004;39(9):870-881.
22. Beger HG, Rau B, Mayer J, Pralle U. Natural course of acute pancreatitis. World J Surg. 1997;21(2):130-135.
23. Ammori BJ. Role of the gut in the course of severe acute pancreatitis. Pancreas. 2003;26(2):122-129.
24. Uhl W, Warshaw A, Imrie C, et al; International Association of Pancreatology. Guidelines for the surgical management of acute pancreatitis. Pancreatology. 2002; 2(6):565-573.
25. Taylor SL, Morgan DL, Denson KD, Lane MM, Pennington LR. A comparison of the Ranson, Glasgow, and APACHE II scoring systems to a multiple organ system score in predicting patient outcome in pancreatitis. Am J Surg. 2005;189(2):219-222.
26. Ji B, Chen XQ, Misek DE, et al. Pancreatic gene expression during the initiation of acute pancreatitis: identification of EGR-1 as a key regulator. Physiol Genomics. 2003;14(1):59-72.
27. Pezzilli R, Billi P, Beltrandi E, et al. Circulating lymphocyte subsets in human acute pancreatitis. Pancreas. 1995;11(1):95-100.
28. Rydzewska G, Rivard N, Morisset J. Dynamics of pancreatic tyrosine kinase and phospholipase D activities in the course of cerulein-induced acute pancreatitis and during regeneration. Pancreas. 1995;10(4):382-388.
29. Huang P, Frohman MA. The potential for phospholipase D as a new therapeutic target. Expert Opin Ther Targets. 2007;11(5):707-716.
30. Foitzik T, Hotz HG, Hotz B, Wittig F, Buhr HJ. Selective inhibition of cyclooxygenase-2 (COX-2) reduces prostaglandin E2 production and attenuates systemic disease sequelae in experimental pancreatitis. Hepatogastroenterology. 2003; 50(52):1159-1162.
31. Paszkowski AS, Rau B, Mayer JM, Moller P, Beger HG. Therapeutic application of caspase 1/interleukin-1beta-converting enzyme inhibitor decreases the death rate in severe acute experimental pancreatitis. Ann Surg. 2002;235(1):68-76.
32. Rau B, Baumgart K, Paszkowski AS, Mayer JM, Beger HG. Clinical relevance of caspase-1 activated cytokines in acute pancreatitis: high correlation of serum interleukin-18 with pancreatic necrosis and systemic complications. Crit Care Med. 2001;29(8):1556-1562.
33. Sarkar A, Hall MW, Exline M, et al. Caspase-1 regulates Escherichia coli sepsis and splenic B cell apoptosis independently of interleukin-1beta and interleukin-18. Am J Respir Crit Care Med. 2006;174(9):1003-1010.
34. Webster KA, Graham RM, Thompson JW, et al. Redox stress and the contributions of BH3-only proteins to infarction. Antioxid Redox Signal. 2006;8(9-10): 1667-1676.
35. Green DR. Life, death, BH3 profiles, and the salmon mousse. Cancer Cell. 2007; 12(2):97-99.
36. Kandil E, Lin YY, Bluth MH, Zhang H, Levi G, Zenilman ME. Dexamethasone mediates protection against acute pancreatitis via upregulation of pancreatitisassociated proteins. World J Gastroenterol. 2006;12(42):6806-6811.
37. Gomez G, Townsend CM Jr, Green D, Rajaraman S, Uchida T, Thompson JC. Involvement of cholecystokinin receptors in the adverse effect of glucocorticoids on diet-induced necrotizing pancreatitis. Surgery. 1989;106(2):230-236.
38. Bluth MH, Bluth MJ, Johns C, Kahn S, Lin YY, Zenilman ME, Cheung WW. Peripheral blood mononuclear cell gene array profiles in patients with overactive bladder [abstract]. J Immunol. 2007;178:132.8. http://www.jimmunol.org/cgi/content/meeting_abstract/178/MeetingAbstracts/ S246-d.