메뉴 건너뛰기




Volumn 1, Issue 7, 2013, Pages 564-573

Bronchodilator reversibility in chronic obstructive pulmonary disease: Use and limitations

Author keywords

[No Author keywords available]

Indexed keywords

BRONCHODILATING AGENT; IPRATROPIUM BROMIDE; ISOPRENALINE; SALBUTAMOL;

EID: 84883466304     PISSN: 22132600     EISSN: None     Source Type: Journal    
DOI: 10.1016/S2213-2600(13)70086-9     Document Type: Review
Times cited : (78)

References (73)
  • 1
    • 84862833566 scopus 로고    scopus 로고
    • Small-airway obstruction and emphysema in chronic obstructive pulmonary disease
    • McDonough JE, Yuan R, Suzuki M, et al. Small-airway obstruction and emphysema in chronic obstructive pulmonary disease. N Engl J Med 2011, 365:1567-1575.
    • (2011) N Engl J Med , vol.365 , pp. 1567-1575
    • McDonough, J.E.1    Yuan, R.2    Suzuki, M.3
  • 2
    • 4344675455 scopus 로고    scopus 로고
    • Pathophysiology of airflow limitation in chronic obstructive pulmonary disease
    • Hogg JC Pathophysiology of airflow limitation in chronic obstructive pulmonary disease. Lancet 2004, 364:709-721.
    • (2004) Lancet , vol.364 , pp. 709-721
    • Hogg, J.C.1
  • 3
    • 0027358977 scopus 로고
    • Exertional breathlessness in patients with chronic airflow limitation. The role of lung hyperinflation
    • O'Donnell DE, Webb KA Exertional breathlessness in patients with chronic airflow limitation. The role of lung hyperinflation. Am Rev Respir Dis 1993, 148:1351-1357.
    • (1993) Am Rev Respir Dis , vol.148 , pp. 1351-1357
    • O'Donnell, D.E.1    Webb, K.A.2
  • 5
    • 33644867170 scopus 로고    scopus 로고
    • The natural history of chronic obstructive pulmonary disease
    • Mannino DM, Watt G, Hole D, et al. The natural history of chronic obstructive pulmonary disease. Eur Respir J 2006, 27:627-643.
    • (2006) Eur Respir J , vol.27 , pp. 627-643
    • Mannino, D.M.1    Watt, G.2    Hole, D.3
  • 6
    • 57149092192 scopus 로고    scopus 로고
    • 1/FVC ratio reduces the misclassification of airway obstruction
    • 1/FVC ratio reduces the misclassification of airway obstruction. Thorax 2008, 63:1046-1051.
    • (2008) Thorax , vol.63 , pp. 1046-1051
    • Swanney, M.P.1    Ruppel, G.2    Enright, P.L.3
  • 7
    • 84873956600 scopus 로고    scopus 로고
    • Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary
    • Vestbo J, Hurd SS, Agusti AG, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med 2013, 187:347-365.
    • (2013) Am J Respir Crit Care Med , vol.187 , pp. 347-365
    • Vestbo, J.1    Hurd, S.S.2    Agusti, A.G.3
  • 8
    • 34548267728 scopus 로고    scopus 로고
    • International variation in the prevalence of COPD (the BOLD Study): a population-based prevalence study
    • Buist AS, McBurnie MA, Vollmer WM, et al. International variation in the prevalence of COPD (the BOLD Study): a population-based prevalence study. Lancet 2007, 370:741-750.
    • (2007) Lancet , vol.370 , pp. 741-750
    • Buist, A.S.1    McBurnie, M.A.2    Vollmer, W.M.3
  • 9
    • 28044444899 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease in five Latin American cities (the PLATINO study): a prevalence study
    • Menezes AM, Perez-Padilla R, Jardim JR, et al. Chronic obstructive pulmonary disease in five Latin American cities (the PLATINO study): a prevalence study. Lancet 2005, 366:1875-1881.
    • (2005) Lancet , vol.366 , pp. 1875-1881
    • Menezes, A.M.1    Perez-Padilla, R.2    Jardim, J.R.3
  • 10
    • 0026793546 scopus 로고
    • Acute bronchodilator trials in chronic obstructive pulmonary disease
    • Nisar M, Earis JE, Pearson MG, Calverley PM Acute bronchodilator trials in chronic obstructive pulmonary disease. Am Rev Respir Dis 1992, 146:555-559.
    • (1992) Am Rev Respir Dis , vol.146 , pp. 555-559
    • Nisar, M.1    Earis, J.E.2    Pearson, M.G.3    Calverley, P.M.4
  • 12
    • 0022359956 scopus 로고
    • The use of criteria for reversibility and obstruction to define patient groups for bronchodilator trials. Influence of clinical diagnosis, spirometric, and anthropometric variables
    • Eliasson O, Degraff AC The use of criteria for reversibility and obstruction to define patient groups for bronchodilator trials. Influence of clinical diagnosis, spirometric, and anthropometric variables. Am Rev Respir Dis 1985, 132:858-864.
    • (1985) Am Rev Respir Dis , vol.132 , pp. 858-864
    • Eliasson, O.1    Degraff, A.C.2
  • 14
    • 34547399133 scopus 로고    scopus 로고
    • Impact of bronchodilator use on the prevalence of COPD in population-based samples
    • Perez-Padilla R, Hallal PC, Vazquez-Garcia JC, et al. Impact of bronchodilator use on the prevalence of COPD in population-based samples. COPD 2007, 4:113-120.
    • (2007) COPD , vol.4 , pp. 113-120
    • Perez-Padilla, R.1    Hallal, P.C.2    Vazquez-Garcia, J.C.3
  • 17
    • 84864016731 scopus 로고    scopus 로고
    • Worldwide patterns of bronchodilator responsiveness: results from the Burden of Obstructive Lung Disease study
    • Tan WC, Vollmer WM, Lamprecht B, et al. Worldwide patterns of bronchodilator responsiveness: results from the Burden of Obstructive Lung Disease study. Thorax 2012, 67:718-726.
    • (2012) Thorax , vol.67 , pp. 718-726
    • Tan, W.C.1    Vollmer, W.M.2    Lamprecht, B.3
  • 18
    • 24644496531 scopus 로고    scopus 로고
    • Interpretative strategies for lung function tests
    • Pellegrino R, Viegi G, Brusasco V, et al. Interpretative strategies for lung function tests. Eur Respir J 2005, 26:948-968.
    • (2005) Eur Respir J , vol.26 , pp. 948-968
    • Pellegrino, R.1    Viegi, G.2    Brusasco, V.3
  • 19
    • 84864015892 scopus 로고    scopus 로고
    • Bronchodilator responsiveness as a phenotypic characteristic of established chronic obstructive pulmonary disease
    • Albert P, Agusti A, Edwards L, et al. Bronchodilator responsiveness as a phenotypic characteristic of established chronic obstructive pulmonary disease. Thorax 2012, 67:701-708.
    • (2012) Thorax , vol.67 , pp. 701-708
    • Albert, P.1    Agusti, A.2    Edwards, L.3
  • 20
    • 0021037448 scopus 로고
    • Intermittent positive pressure breathing therapy of chronic obstructive pulmonary disease. A clinical trial
    • [No authors listed]
    • Intermittent positive pressure breathing therapy of chronic obstructive pulmonary disease. A clinical trial. Ann Intern Med 1983, 99:612-620. [No authors listed].
    • (1983) Ann Intern Med , vol.99 , pp. 612-620
  • 21
    • 0027564322 scopus 로고
    • Lung volumes and forced ventilatory flows. Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal. Official Statement of the European Respiratory Society
    • Quanjer PH, Tammeling GJ, Cotes JE, et al. Lung volumes and forced ventilatory flows. Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal. Official Statement of the European Respiratory Society. Eur Respir J 1993, 16:5-40.
    • (1993) Eur Respir J , vol.16 , pp. 5-40
    • Quanjer, P.H.1    Tammeling, G.J.2    Cotes, J.E.3
  • 22
    • 21744460289 scopus 로고    scopus 로고
    • ATS/ERS Task Force. Standardisation of spirometry
    • Miller MR, Hankinson J, Brusasco V, et al. ATS/ERS Task Force. Standardisation of spirometry. Eur Respir J 2005, 26:319-338.
    • (2005) Eur Respir J , vol.26 , pp. 319-338
    • Miller, M.R.1    Hankinson, J.2    Brusasco, V.3
  • 23
    • 0037425745 scopus 로고    scopus 로고
    • Combined salmeterol and fluticasone in the treatment of chronic obstructive pulmonary disease: a randomised controlled trial
    • Calverley P, Pauwels R, Vestbo J, et al. Combined salmeterol and fluticasone in the treatment of chronic obstructive pulmonary disease: a randomised controlled trial. Lancet 2003, 361:449-456.
    • (2003) Lancet , vol.361 , pp. 449-456
    • Calverley, P.1    Pauwels, R.2    Vestbo, J.3
  • 24
    • 0347473812 scopus 로고    scopus 로고
    • Maintenance therapy with budesonide and formoterol in chronic obstructive pulmonary disease
    • Calverley PM, Boonsawat W, Cseke Z, Zhong N, Peterson S, Olsson H Maintenance therapy with budesonide and formoterol in chronic obstructive pulmonary disease. Eur Respir J 2003, 22:912-919.
    • (2003) Eur Respir J , vol.22 , pp. 912-919
    • Calverley, P.M.1    Boonsawat, W.2    Cseke, Z.3    Zhong, N.4    Peterson, S.5    Olsson, H.6
  • 25
    • 0037108632 scopus 로고    scopus 로고
    • Effectiveness of fluticasone propionate and salmeterol combination delivered via the Diskus device in the treatment of chronic obstructive pulmonary disease
    • Mahler DA, Wire P, Horstman D, et al. Effectiveness of fluticasone propionate and salmeterol combination delivered via the Diskus device in the treatment of chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2002, 166:1084-1091.
    • (2002) Am J Respir Crit Care Med , vol.166 , pp. 1084-1091
    • Mahler, D.A.1    Wire, P.2    Horstman, D.3
  • 26
    • 24644492301 scopus 로고    scopus 로고
    • Prevention of exacerbations of chronic obstructive pulmonary disease with tiotropium, a once-daily inhaled anticholinergic bronchodilator: a randomized trial
    • Niewoehner DE, Rice K, Cote C, et al. Prevention of exacerbations of chronic obstructive pulmonary disease with tiotropium, a once-daily inhaled anticholinergic bronchodilator: a randomized trial. Ann Intern Med 2005, 143:317-326.
    • (2005) Ann Intern Med , vol.143 , pp. 317-326
    • Niewoehner, D.E.1    Rice, K.2    Cote, C.3
  • 27
    • 0028318612 scopus 로고
    • In chronic obtructive pulmonary disease, a combination of ipratropium and albuterol is more effective than either agent alone. An 85-day multicenter trial
    • COMBIVENT Inhalation Aerosol Study Group
    • In chronic obtructive pulmonary disease, a combination of ipratropium and albuterol is more effective than either agent alone. An 85-day multicenter trial. Chest 1994, 105:1411-1419. COMBIVENT Inhalation Aerosol Study Group.
    • (1994) Chest , vol.105 , pp. 1411-1419
  • 28
    • 0025304709 scopus 로고
    • Assessment of reversibility of airway obstruction in patients with chronic obstructive airways disease
    • Nisar M, Walshaw M, Earis JE, Pearson MG, Calverley PM Assessment of reversibility of airway obstruction in patients with chronic obstructive airways disease. Thorax 1990, 45:190-194.
    • (1990) Thorax , vol.45 , pp. 190-194
    • Nisar, M.1    Walshaw, M.2    Earis, J.E.3    Pearson, M.G.4    Calverley, P.M.5
  • 29
    • 0042354673 scopus 로고    scopus 로고
    • Prednisolone response in patients with chronic obstructive pulmonary disease: results from the ISOLDE study
    • Burge PS, Calverley PM, Jones PW, Spencer S, Anderson JA Prednisolone response in patients with chronic obstructive pulmonary disease: results from the ISOLDE study. Thorax 2003, 58:654-658.
    • (2003) Thorax , vol.58 , pp. 654-658
    • Burge, P.S.1    Calverley, P.M.2    Jones, P.W.3    Spencer, S.4    Anderson, J.A.5
  • 30
    • 0038440501 scopus 로고    scopus 로고
    • Genome-wide linkage analysis of bronchodilator responsiveness and post-bronchodilator spirometric phenotypes in chronic obstructive pulmonary disease
    • Palmer LJ, Celedon JC, Chapman HA, Speizer FE, Weiss ST, Silverman EK Genome-wide linkage analysis of bronchodilator responsiveness and post-bronchodilator spirometric phenotypes in chronic obstructive pulmonary disease. Hum Mol Genet 2003, 12:1199-1210.
    • (2003) Hum Mol Genet , vol.12 , pp. 1199-1210
    • Palmer, L.J.1    Celedon, J.C.2    Chapman, H.A.3    Speizer, F.E.4    Weiss, S.T.5    Silverman, E.K.6
  • 31
    • 0022625717 scopus 로고
    • Bronchodilator response in chronic obstructive pulmonary disease
    • Anthonisen NR, Wright EC Bronchodilator response in chronic obstructive pulmonary disease. Am Rev Respir Dis 1986, 133:814-819.
    • (1986) Am Rev Respir Dis , vol.133 , pp. 814-819
    • Anthonisen, N.R.1    Wright, E.C.2
  • 32
    • 80053350305 scopus 로고    scopus 로고
    • Changes in forced expiratory volume in 1 second over time in COPD
    • Vestbo J, Edwards LD, Scanlon PD, et al. Changes in forced expiratory volume in 1 second over time in COPD. N Engl J Med 2011, 365:1184-1192.
    • (2011) N Engl J Med , vol.365 , pp. 1184-1192
    • Vestbo, J.1    Edwards, L.D.2    Scanlon, P.D.3
  • 34
    • 0041853629 scopus 로고    scopus 로고
    • Bronchodilator reversibility testing in chronic obstructive pulmonary disease
    • Calverley PM, Burge PS, Spencer S, Anderson JA, Jones PW Bronchodilator reversibility testing in chronic obstructive pulmonary disease. Thorax 2003, 58:659-664.
    • (2003) Thorax , vol.58 , pp. 659-664
    • Calverley, P.M.1    Burge, P.S.2    Spencer, S.3    Anderson, J.A.4    Jones, P.W.5
  • 35
    • 42949152368 scopus 로고    scopus 로고
    • Bronchodilator responsiveness in patients with COPD
    • Tashkin DP, Celli B, Decramer M, et al. Bronchodilator responsiveness in patients with COPD. Eur Respir J 2008, 31:742-750.
    • (2008) Eur Respir J , vol.31 , pp. 742-750
    • Tashkin, D.P.1    Celli, B.2    Decramer, M.3
  • 36
    • 77951950812 scopus 로고    scopus 로고
    • Prevalence and clinical correlates of bronchoreversibility in severe emphysema
    • Han MK, Wise R, Mumford J, et al. Prevalence and clinical correlates of bronchoreversibility in severe emphysema. Eur Respir J 2010, 35:1048-1056.
    • (2010) Eur Respir J , vol.35 , pp. 1048-1056
    • Han, M.K.1    Wise, R.2    Mumford, J.3
  • 37
    • 78651083393 scopus 로고    scopus 로고
    • Acute bronchodilator responsiveness and health outcomes in COPD patients in the UPLIFT trial
    • Hanania NA, Sharafkhaneh A, Celli B, et al. Acute bronchodilator responsiveness and health outcomes in COPD patients in the UPLIFT trial. Respir Res 2011, 12:6.
    • (2011) Respir Res , vol.12 , pp. 6
    • Hanania, N.A.1    Sharafkhaneh, A.2    Celli, B.3
  • 38
    • 51049083805 scopus 로고    scopus 로고
    • Use of respiratory medication in five Latin American cities: the PLATINO study
    • PLATINO Team
    • Montes de Oca M, Tálamo C, Perez-Padilla R, et al. Use of respiratory medication in five Latin American cities: the PLATINO study. Pulm Pharmacol Ther 2008, 21:788-793. PLATINO Team.
    • (2008) Pulm Pharmacol Ther , vol.21 , pp. 788-793
    • Montes de Oca, M.1    Tálamo, C.2    Perez-Padilla, R.3
  • 39
    • 0034847496 scopus 로고    scopus 로고
    • Alternative methods for assessing bronchodilator reversibility in chronic obstructive pulmonary disease
    • Hadcroft J, Calverley PM Alternative methods for assessing bronchodilator reversibility in chronic obstructive pulmonary disease. Thorax 2001, 56:713-720.
    • (2001) Thorax , vol.56 , pp. 713-720
    • Hadcroft, J.1    Calverley, P.M.2
  • 40
    • 0024400242 scopus 로고
    • Dose response to ipratropium as a nebulized solution in patients with chronic obstructive pulmonary disease. A three-center study
    • Gross NJ, Petty TL, Friedman M, Skorodin MS, Silvers GW, Donohue JF Dose response to ipratropium as a nebulized solution in patients with chronic obstructive pulmonary disease. A three-center study. Am Rev Respir Dis 1989, 139:1188-1191.
    • (1989) Am Rev Respir Dis , vol.139 , pp. 1188-1191
    • Gross, N.J.1    Petty, T.L.2    Friedman, M.3    Skorodin, M.S.4    Silvers, G.W.5    Donohue, J.F.6
  • 41
    • 3042804527 scopus 로고    scopus 로고
    • Routine nebulized ipratropium and albuterol together are better than either alone in COPD
    • The COMBIVENT Inhalation Solution Study Group
    • Routine nebulized ipratropium and albuterol together are better than either alone in COPD. Chest 1997, 112:1514-1521. The COMBIVENT Inhalation Solution Study Group.
    • (1997) Chest , vol.112 , pp. 1514-1521
  • 42
    • 53749102775 scopus 로고    scopus 로고
    • A 4-year trial of tiotropium in chronic obstructive pulmonary disease
    • Tashkin DP, Celli B, Senn S, et al. A 4-year trial of tiotropium in chronic obstructive pulmonary disease. N Engl J Med 2008, 359:1543-1554.
    • (2008) N Engl J Med , vol.359 , pp. 1543-1554
    • Tashkin, D.P.1    Celli, B.2    Senn, S.3
  • 43
    • 77956084309 scopus 로고    scopus 로고
    • Management of stable chronic obstructive pulmonary disease in primary and secondary care: summary of updated NICE guidance
    • published online June 25.
    • O'Reilly J, Jones MM, Parnham J, Lovibond K, Rudolf M Management of stable chronic obstructive pulmonary disease in primary and secondary care: summary of updated NICE guidance. BMJ 2010, published online June 25. 10.1136/bmj.c3134.
    • (2010) BMJ
    • O'Reilly, J.1    Jones, M.M.2    Parnham, J.3    Lovibond, K.4    Rudolf, M.5
  • 44
    • 0034727453 scopus 로고    scopus 로고
    • Sputum eosinophilia and short-term response to prednisolone in chronic obstructive pulmonary disease: a randomised controlled trial
    • Brightling CE, Monteiro W, Ward R, et al. Sputum eosinophilia and short-term response to prednisolone in chronic obstructive pulmonary disease: a randomised controlled trial. Lancet 2000, 356:1480-1485.
    • (2000) Lancet , vol.356 , pp. 1480-1485
    • Brightling, C.E.1    Monteiro, W.2    Ward, R.3
  • 45
    • 0032930094 scopus 로고    scopus 로고
    • Reversible and irreversible airflow obstruction as predictor of overall mortality in asthma and chronic obstructive pulmonary disease
    • Hansen EF, Phanareth K, Laursen LC, Kok-Jensen A, Dirksen A Reversible and irreversible airflow obstruction as predictor of overall mortality in asthma and chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1999, 159:1267-1271.
    • (1999) Am J Respir Crit Care Med , vol.159 , pp. 1267-1271
    • Hansen, E.F.1    Phanareth, K.2    Laursen, L.C.3    Kok-Jensen, A.4    Dirksen, A.5
  • 46
    • 44849084468 scopus 로고    scopus 로고
    • A PEACE-ful solution to COPD exacerbations?
    • Albert P, Calverley P A PEACE-ful solution to COPD exacerbations?. Lancet 2008, 371:1975-1976.
    • (2008) Lancet , vol.371 , pp. 1975-1976
    • Albert, P.1    Calverley, P.2
  • 47
    • 0028859134 scopus 로고
    • A simple method to detect expiratory flow limitation during spontaneous breathing
    • Koulouris NG, Valta P, Lavoie A, et al. A simple method to detect expiratory flow limitation during spontaneous breathing. Eur Respir J 1995, 8:306-313.
    • (1995) Eur Respir J , vol.8 , pp. 306-313
    • Koulouris, N.G.1    Valta, P.2    Lavoie, A.3
  • 48
    • 13444269557 scopus 로고    scopus 로고
    • Flow limitation and dynamic hyperinflation: key concepts in modern respiratory physiology
    • Calverley PM, Koulouris NG Flow limitation and dynamic hyperinflation: key concepts in modern respiratory physiology. Eur Respir J 2005, 25:186-199.
    • (2005) Eur Respir J , vol.25 , pp. 186-199
    • Calverley, P.M.1    Koulouris, N.G.2
  • 49
    • 79957507053 scopus 로고    scopus 로고
    • Respiratory system impedance with impulse oscillometry in healthy and COPD subjects: ECLIPSE baseline results
    • Crim C, Celli B, Edwards LD, et al. Respiratory system impedance with impulse oscillometry in healthy and COPD subjects: ECLIPSE baseline results. Respir Med 2011, 105:1069-1078.
    • (2011) Respir Med , vol.105 , pp. 1069-1078
    • Crim, C.1    Celli, B.2    Edwards, L.D.3
  • 51
    • 0031751790 scopus 로고    scopus 로고
    • Effect of salbutamol on dynamic hyperinflation in chronic obstructive pulmonary disease patients
    • Tantucci C, Duguet A, Similowski T, Zelter M, Derenne JP, Milic-Emili J Effect of salbutamol on dynamic hyperinflation in chronic obstructive pulmonary disease patients. Eur Respir J 1998, 12:799-804.
    • (1998) Eur Respir J , vol.12 , pp. 799-804
    • Tantucci, C.1    Duguet, A.2    Similowski, T.3    Zelter, M.4    Derenne, J.P.5    Milic-Emili, J.6
  • 52
    • 84455201660 scopus 로고    scopus 로고
    • Evolution of dyspnea during exercise in chronic obstructive pulmonary disease: impact of critical volume constraints
    • Laveneziana P, Webb KA, Ora J, Wadell K, O'Donnell DE Evolution of dyspnea during exercise in chronic obstructive pulmonary disease: impact of critical volume constraints. Am J Respir Crit Care Med 2011, 184:1367-1373.
    • (2011) Am J Respir Crit Care Med , vol.184 , pp. 1367-1373
    • Laveneziana, P.1    Webb, K.A.2    Ora, J.3    Wadell, K.4    O'Donnell, D.E.5
  • 53
    • 3543055330 scopus 로고    scopus 로고
    • Effect of salmeterol on the ventilatory response to exercise in chronic obstructive pulmonary disease
    • O'Donnell DE, Voduc N, Fitzpatrick M, Webb KA Effect of salmeterol on the ventilatory response to exercise in chronic obstructive pulmonary disease. Eur Respir J 2004, 24:86-94.
    • (2004) Eur Respir J , vol.24 , pp. 86-94
    • O'Donnell, D.E.1    Voduc, N.2    Fitzpatrick, M.3    Webb, K.A.4
  • 54
    • 0026694863 scopus 로고
    • Bronchodilator reversibility, exercise performance and breathlessness in stable chronic obstructive pulmonary disease
    • Hay JG, Stone P, Carter J, et al. Bronchodilator reversibility, exercise performance and breathlessness in stable chronic obstructive pulmonary disease. Eur Respir J 1992, 5:659-664.
    • (1992) Eur Respir J , vol.5 , pp. 659-664
    • Hay, J.G.1    Stone, P.2    Carter, J.3
  • 55
    • 33847172367 scopus 로고    scopus 로고
    • Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease
    • Calverley PM, Anderson JA, Celli B, et al. Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease. N Engl J Med 2007, 356:775-789.
    • (2007) N Engl J Med , vol.356 , pp. 775-789
    • Calverley, P.M.1    Anderson, J.A.2    Celli, B.3
  • 56
    • 0032778472 scopus 로고    scopus 로고
    • Spirometric correlates of improvement in exercise performance after anticholinergic therapy in chronic obstructive pulmonary disease
    • O'Donnell DE, Lam M, Webb KA Spirometric correlates of improvement in exercise performance after anticholinergic therapy in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1999, 160:542-549.
    • (1999) Am J Respir Crit Care Med , vol.160 , pp. 542-549
    • O'Donnell, D.E.1    Lam, M.2    Webb, K.A.3
  • 57
    • 0036206421 scopus 로고    scopus 로고
    • Response of lung volumes to inhaled salbutamol in a large population of patients with severe hyperinflation
    • Newton MF, O'Donnell DE, Forkert L Response of lung volumes to inhaled salbutamol in a large population of patients with severe hyperinflation. Chest 2002, 121:1042-1050.
    • (2002) Chest , vol.121 , pp. 1042-1050
    • Newton, M.F.1    O'Donnell, D.E.2    Forkert, L.3
  • 58
    • 45949104550 scopus 로고    scopus 로고
    • The volumetric response to bronchodilators in stable chronic obstructive pulmonary disease
    • Walker PP, Calverley PM The volumetric response to bronchodilators in stable chronic obstructive pulmonary disease. COPD 2008, 5:147-152.
    • (2008) COPD , vol.5 , pp. 147-152
    • Walker, P.P.1    Calverley, P.M.2
  • 59
    • 2442555774 scopus 로고    scopus 로고
    • Assessment of emphysema in COPD: a functional and radiologic study
    • Cerveri I, Dore R, Corsico A, et al. Assessment of emphysema in COPD: a functional and radiologic study. Chest 2004, 125:1714-1718.
    • (2004) Chest , vol.125 , pp. 1714-1718
    • Cerveri, I.1    Dore, R.2    Corsico, A.3
  • 60
    • 0024467177 scopus 로고
    • Cholinergic bronchomotor tone in COPD. Estimates of its amount in comparison with that in normal subjects
    • Gross NJ, Co E, Skorodin MS Cholinergic bronchomotor tone in COPD. Estimates of its amount in comparison with that in normal subjects. Chest 1989, 96:984-987.
    • (1989) Chest , vol.96 , pp. 984-987
    • Gross, N.J.1    Co, E.2    Skorodin, M.S.3
  • 61
    • 14444279391 scopus 로고    scopus 로고
    • Severity of airflow limitation is associated with severity of airway inflammation in smokers
    • Di Stefano A, Capelli A, Lusuardi M, et al. Severity of airflow limitation is associated with severity of airway inflammation in smokers. Am J Respir Crit Care Med 1998, 158:1277-1285.
    • (1998) Am J Respir Crit Care Med , vol.158 , pp. 1277-1285
    • Di Stefano, A.1    Capelli, A.2    Lusuardi, M.3
  • 62
    • 84861870244 scopus 로고    scopus 로고
    • Evasion of COPD in smokers: at what price?
    • Cosio MG, Saetta M Evasion of COPD in smokers: at what price?. Eur Respir J 2012, 39:1298-1303.
    • (2012) Eur Respir J , vol.39 , pp. 1298-1303
    • Cosio, M.G.1    Saetta, M.2
  • 63
    • 84864497033 scopus 로고    scopus 로고
    • Mast cell infiltration discriminates between histopathological phenotypes of chronic obstructive pulmonary disease
    • Ballarin A, Bazzan E, Zenteno RH, et al. Mast cell infiltration discriminates between histopathological phenotypes of chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2012, 186:233-239.
    • (2012) Am J Respir Crit Care Med , vol.186 , pp. 233-239
    • Ballarin, A.1    Bazzan, E.2    Zenteno, R.H.3
  • 65
    • 0023190465 scopus 로고
    • 1 and bronchodilator responsiveness in patients with obstructive ventilatory defects
    • 1 and bronchodilator responsiveness in patients with obstructive ventilatory defects. Thorax 1987, 42:487-490.
    • (1987) Thorax , vol.42 , pp. 487-490
    • Tweeddale, P.M.1    Alexander, F.2    McHardy, G.J.3
  • 66
    • 28444431591 scopus 로고    scopus 로고
    • Risk of severe asthma episodes predicted from fluctuation analysis of airway function
    • Frey U, Brodbeck T, Majumdar A, et al. Risk of severe asthma episodes predicted from fluctuation analysis of airway function. Nature 2005, 438:667-670.
    • (2005) Nature , vol.438 , pp. 667-670
    • Frey, U.1    Brodbeck, T.2    Majumdar, A.3
  • 67
    • 52049123806 scopus 로고    scopus 로고
    • Complexity of chronic asthma and chronic obstructive pulmonary disease: implications for risk assessment, and disease progression and control
    • Frey U, Suki B Complexity of chronic asthma and chronic obstructive pulmonary disease: implications for risk assessment, and disease progression and control. Lancet 2008, 372:1088-1099.
    • (2008) Lancet , vol.372 , pp. 1088-1099
    • Frey, U.1    Suki, B.2
  • 68
    • 21744440287 scopus 로고    scopus 로고
    • Bronchodilator reversibility in COPD: the roguish but harmless little brother of airway hyperresponsiveness?
    • Hansen EF, Vestbo J Bronchodilator reversibility in COPD: the roguish but harmless little brother of airway hyperresponsiveness?. Eur Respir J 2005, 26:6-7.
    • (2005) Eur Respir J , vol.26 , pp. 6-7
    • Hansen, E.F.1    Vestbo, J.2
  • 72
    • 23744451716 scopus 로고    scopus 로고
    • Roflumilast-an oral anti-inflammatory treatment for chronic obstructive pulmonary disease: a randomised controlled trial
    • Rabe KF, Bateman ED, O'Donnell D, Witte S, Bredenbroker D, Bethke TD Roflumilast-an oral anti-inflammatory treatment for chronic obstructive pulmonary disease: a randomised controlled trial. Lancet 2005, 366:563-571.
    • (2005) Lancet , vol.366 , pp. 563-571
    • Rabe, K.F.1    Bateman, E.D.2    O'Donnell, D.3    Witte, S.4    Bredenbroker, D.5    Bethke, T.D.6
  • 73


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.