Fusion protein Isl1-Lhx3 specifies motor neuron fate by inducing motor neuron genes and concomitantly suppressing the interneuron programs

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 9, 2012, Pages 3383-3388

  Lee, Seunghee ^a   Cuvillier, James M ^b   Lee, Bora ^a   Shen, Rongkun ^a   Lee, Jae W ^a   Lee, Soo Kyung ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYBRID PROTEIN; ISL1 LHX3 FUSION PROTEIN; ISL1 PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR LHX3; UNCLASSIFIED DRUG;

ARTICLE; CELL DIFFERENTIATION; CELL FATE; EMBRYONIC STEM CELL; GENE EXPRESSION; INTERNEURON; MOTONEURON; PRIORITY JOURNAL; RNA SEQUENCE; SPINAL CORD; STEM CELL; UPREGULATION;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE, TUMOR; CELL LINEAGE; CELLS, CULTURED; CHICK EMBRYO; EMBRYONIC STEM CELLS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; INTERNEURONS; LIM-HOMEODOMAIN PROTEINS; MICE; MOLECULAR SEQUENCE DATA; MOTOR NEURONS; MYOBLASTS; NEURAL TUBE; NEUROGENESIS; PROTEIN STRUCTURE, TERTIARY; RATS; RECOMBINANT FUSION PROTEINS; SEQUENCE ALIGNMENT; SPINAL CORD; TRANSCRIPTION FACTORS; TRANSCRIPTOME;

ERINACEIDAE;

EID: 84863275669     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1114515109     Document Type: Article

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