메뉴 건너뛰기




Volumn 9, Issue 4, 2013, Pages 731-738

Distribution of selected gene polymorphisms of UGT1A1 in a Saudi population

Author keywords

Gene polymorphism; Glucuronidation; Saudi Arabians; UDP glucuronosyltransferase 1A1

Indexed keywords

GENOMIC DNA; GLUCURONOSYLTRANSFERASE 1A1;

EID: 84883431232     PISSN: 17341922     EISSN: None     Source Type: Journal    
DOI: 10.5114/aoms.2013.37012     Document Type: Article
Times cited : (14)

References (30)
  • 1
    • 0030778114 scopus 로고    scopus 로고
    • Structure and function of uridine diphosphate glucuronosyltransferases
    • Meech R, Mackenzie PI. Structure and function of uridine diphosphate glucuronosyltransferases. Clin Exp Pharmacol Physiol 1997; 24: 907-15.
    • (1997) Clin Exp Pharmacol Physiol , vol.24 , pp. 907-915
    • Meech, R.1    Mackenzie, P.I.2
  • 2
    • 0032519431 scopus 로고    scopus 로고
    • Genetic pre disposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes
    • Iyer L, King CD, Whitington PF, et al. Genetic pre disposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes. J Clin Invest 1998; 101: 847-54.
    • (1998) J Clin Invest , vol.101 , pp. 847-854
    • Iyer, L.1    King, C.D.2    Whitington, P.F.3
  • 3
    • 0027991904 scopus 로고
    • Investigation of the substrate specificity of a cloned expressed human bilirubin UDP-glucuronosyltransferase: UDP-sugar specificity and involvement in steroid and xenobiotic glucuronidation
    • Senafi SB, Clarke DJ, Burchell B. Investigation of the substrate specificity of a cloned expressed human bilirubin UDP-glucuronosyltransferase: UDP-sugar specificity and involvement in steroid and xenobiotic glucuronidation. Biochem J 1994; 303: 233-40.
    • (1994) Biochem J , vol.303 , pp. 233-240
    • Senafi, S.B.1    Clarke, D.J.2    Burchell, B.3
  • 4
    • 0034128936 scopus 로고    scopus 로고
    • Human UDP-glucurono syltransferases: Metabolism, expression, and disease
    • Tukey RH, Strassburg CP. Human UDP-glucurono syltransferases: Metabolism, expression, and disease. Annu Rev Pharmacol Toxicol 2000; 40: 581-616.
    • (2000) Annu Rev Pharmacol Toxicol , vol.40 , pp. 581-616
    • Tukey, R.H.1    Strassburg, C.P.2
  • 5
    • 0032493441 scopus 로고    scopus 로고
    • Racial variability in the UDP-glucuronosyltransferase 1 (UGT1A1) promoter: A balanced polymorphism for regulation of bilirubin metabolism?
    • Beutler E, Gelbart T, Demina A. Racial variability in the UDP-glucuronosyltransferase 1 (UGT1A1) promoter: A balanced polymorphism for regulation of bilirubin metabolism? Proc Natl Acad Sci U S A 1998; 95: 8170-4.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 8170-8174
    • Beutler, E.1    Gelbart, T.2    Demina, A.3
  • 6
    • 0030030762 scopus 로고    scopus 로고
    • Genetic variation in bilirubin UPD-glucuronosyltransferase gene promoter and Gilbert's syndrome
    • Monaghan G, Ryan M, Seddon R, Hume R, Burchell B. Genetic variation in bilirubin UPD-glucuronosyltransferase gene promoter and Gilbert's syndrome. Lancet 1996; 347: 578-81.
    • (1996) Lancet , vol.347 , pp. 578-581
    • Monaghan, G.1    Ryan, M.2    Seddon, R.3    Hume, R.4    Burchell, B.5
  • 7
    • 18444399926 scopus 로고    scopus 로고
    • Identification of a defect in the UGT1A1 gene promoter and its association with hyperbilirubinemia
    • Sugatani J, Yamakawa K, Yoshinari K, et al. Identification of a defect in the UGT1A1 gene promoter and its association with hyperbilirubinemia. Biochem Biophys Res Commun 2002; 292: 492-7.
    • (2002) Biochem Biophys Res Commun , vol.292 , pp. 492-497
    • Sugatani, J.1    Yamakawa, K.2    Yoshinari, K.3
  • 8
    • 0027739943 scopus 로고
    • Identification of defect in the genes for bilirubin UDP-glucuronosyl- transferase in a patient with Crigler-Najjar syndrome type II
    • Aono S, Yamada Y, Keino H, et al. Identification of defect in the genes for bilirubin UDP-glucuronosyl-transferase in a patient with Crigler-Najjar syndrome type II. Biochem Biophys Res Commun 1993; 197: 1239-44.
    • (1993) Biochem Biophys Res Commun , vol.197 , pp. 1239-1244
    • Aono, S.1    Yamada, Y.2    Keino, H.3
  • 9
    • 34748822655 scopus 로고    scopus 로고
    • Influence of mutations associated with Gilbert and Crigler-Najjar type II syndromes on the glucuronidation kinetics of bilirubin and other UDP-glucuronosyltransferase 1A substrates
    • Udomuksorn W, Elliot DJ, Lewis BC, Mackenzie PI, Yoovathaworn K, Miners JO. Influence of mutations associated with Gilbert and Crigler-Najjar type II syndromes on the glucuronidation kinetics of bilirubin and other UDP-glucuronosyltransferase 1A substrates. Pharmacogenet Genomics 2007; 17: 1017-29.
    • (2007) Pharmacogenet Genomics , vol.17 , pp. 1017-1029
    • Udomuksorn, W.1    Elliot, D.J.2    Lewis, B.C.3    Mackenzie, P.I.4    Yoovathaworn, K.5    Miners, J.O.6
  • 10
    • 0031719562 scopus 로고    scopus 로고
    • Neonatal hyper bilirubinemia and mutation of the bilirubin uridine diphosphate-glucuronosyltransferase gene: A common missense mutation among Japanese, Koreans and Chinese
    • Akaba K, Kimura T, Sasaki A, et al. Neonatal hyper bilirubinemia and mutation of the bilirubin uridine diphosphate-glucuronosyltransferase gene: A common missense mutation among Japanese, Koreans and Chinese. Biochem Mol Biol Int 1998; 46: 21-6.
    • (1998) Biochem Mol Biol Int , vol.46 , pp. 21-26
    • Akaba, K.1    Kimura, T.2    Sasaki, A.3
  • 11
    • 0033816138 scopus 로고    scopus 로고
    • Variations of the bilirubin uridine-diphosphoglucuronosyl transferase 1A1 gene in healthy Taiwanese
    • Huang CS, Luo GA, Huang ML, Yu SC, Yang SS. Variations of the bilirubin uridine-diphosphoglucuronosyl transferase 1A1 gene in healthy Taiwanese. Pharmacogenetics 2000; 10: 539-44.
    • (2000) Pharmacogenetics , vol.10 , pp. 539-544
    • Huang, C.S.1    Luo, G.A.2    Huang, M.L.3    Yu, S.C.4    Yang, S.S.5
  • 12
    • 79251593578 scopus 로고    scopus 로고
    • Effects of UDP-glucuronosyltransferase polymorphisms on the pharmacokinetics of ezetimibe in healthy subjects
    • Bae JW, Choi CI, Lee JH, Jang CG, Chung MW, Lee SY. Effects of UDP-glucuronosyltransferase polymorphisms on the pharmacokinetics of ezetimibe in healthy subjects. Eur J Clin Pharmacol 2011; 67: 39-45.
    • (2011) Eur J Clin Pharmacol , vol.67 , pp. 39-45
    • Bae, J.W.1    Choi, C.I.2    Lee, J.H.3    Jang, C.G.4    Chung, M.W.5    Lee, S.Y.6
  • 13
    • 31044452504 scopus 로고    scopus 로고
    • Haplotype structures of the UGT1A gene complex in a Japanese population
    • Saeki M, Saito Y, Jinno H, et al. Haplotype structures of the UGT1A gene complex in a Japanese population. Pharmacogenomics J 2006; 6: 63-75.
    • (2006) Pharmacogenomics J , vol.6 , pp. 63-75
    • Saeki, M.1    Saito, Y.2    Jinno, H.3
  • 14
    • 17044450136 scopus 로고    scopus 로고
    • Frequent co-occurrence of the TATA box mutation associated with Gilbert's syndrome (UGT1A1*28) with other poly morphisms of the UDP-glucuronosyltransferase-1 locus (UGT1A6*2 and UGT1A7*3) in Caucasians and Egyptians
    • Kohle C, Mohrle B, Munzel PA, et al. Frequent co-occurrence of the TATA box mutation associated with Gilbert's syndrome (UGT1A1*28) with other poly morphisms of the UDP-glucuronosyltransferase-1 locus (UGT1A6*2 and UGT1A7*3) in Caucasians and Egyptians. Biochem Pharmacol 2003; 65: 1521-7.
    • (2003) Biochem Pharmacol , vol.65 , pp. 1521-1527
    • Kohle, C.1    Mohrle, B.2    Munzel, P.A.3
  • 15
    • 0038351780 scopus 로고    scopus 로고
    • The global distribution of length polymorphisms of the promoters of the glucuronosyltransferase 1 gene (UGT1A1): Hematologic and evolutionary implications
    • Premawardhena A, Fisher CA, Liu YT, et al. The global distribution of length polymorphisms of the promoters of the glucuronosyltransferase 1 gene (UGT1A1): Hematologic and evolutionary implications. Blood Cells Mol Dis 2003; 31: 98-101.
    • (2003) Blood Cells Mol Dis , vol.31 , pp. 98-101
    • Premawardhena, A.1    Fisher, C.A.2    Liu, Y.T.3
  • 16
    • 12244271026 scopus 로고    scopus 로고
    • Haplotype structure of the UDP-glucuronosyltransferase 1A1 promoter in different ethnic groups
    • Innocenti F, Grimsley C, Das S, et al. Haplotype structure of the UDP-glucuronosyltransferase 1A1 promoter in different ethnic groups. Pharmacogenetics 2002; 12: 725-33.
    • (2002) Pharmacogenetics , vol.12 , pp. 725-733
    • Innocenti, F.1    Grimsley, C.2    Das, S.3
  • 18
    • 14044279224 scopus 로고    scopus 로고
    • Racial variability in haplotype frequencies of UGT1A1 and glucuronidation activity of a novel single nucleotide polymorphism 686C T (P229L) found in an African-American
    • Kaniwa N, Kurose K, Jinno H, et al. Racial variability in haplotype frequencies of UGT1A1 and glucuronidation activity of a novel single nucleotide polymorphism 686C T (P229L) found in an African-American. Drug Metab Dispos 2005; 33: 458-65.
    • (2005) Drug Metab Dispos , vol.33 , pp. 458-465
    • Kaniwa, N.1    Kurose, K.2    Jinno, H.3
  • 19
    • 0034671387 scopus 로고    scopus 로고
    • Polymorphisms of UDPglucuronosyltransferase gene and irinotecan toxicity: A pharmacogenetic analysis
    • Ando Y, Saka H, Ando M, et al. Polymorphisms of UDPglucuronosyltransferase gene and irinotecan toxicity: A pharmacogenetic analysis. Cancer Res 2000; 60: 6921-6.
    • (2000) Cancer Res , vol.60 , pp. 6921-6926
    • Ando, Y.1    Saka, H.2    Ando, M.3
  • 20
    • 0028867826 scopus 로고
    • The genetic basis of the reduced expression of bilirubin UDPglucuronosyltransferase 1 in Gilbert's syndrome
    • Bosma PJ, Chowdhury JR, Bakker C, et al. The genetic basis of the reduced expression of bilirubin UDPglucuronosyltransferase 1 in Gilbert's syndrome. N Engl J Med 1995; 333: 1171-5.
    • (1995) N Engl J Med , vol.333 , pp. 1171-1175
    • Bosma, P.J.1    Chowdhury, J.R.2    Bakker, C.3
  • 21
    • 77955166242 scopus 로고    scopus 로고
    • Dose-dependent association between UGT1A1*28 genotype and irinotecan-induced neutropenia: Low doses also increase risk
    • Hu ZY, Yu Q, Pei Q, Guo C. Dose-dependent association between UGT1A1*28 genotype and irinotecan-induced neutropenia: Low doses also increase risk. Clin Cancer Res 2010; 16: 3832-42.
    • (2010) Clin Cancer Res , vol.16 , pp. 3832-3842
    • Hu, Z.Y.1    Yu, Q.2    Pei, Q.3    Guo, C.4
  • 22
    • 0028904620 scopus 로고
    • Analysis of genes for bilirubin UDP-glucuronosyltransferase in Gilbert's syndrome
    • Aono S, Adachi Y, Uyama E, et al. Analysis of genes for bilirubin UDP-glucuronosyltransferase in Gilbert's syndrome. Lancet 1995; 345: 958-9.
    • (1995) Lancet , vol.345 , pp. 958-959
    • Aono, S.1    Adachi, Y.2    Uyama, E.3
  • 23
    • 0038275905 scopus 로고    scopus 로고
    • Glucuro nidation of 7-ethyl-10-hydroxycamptothecin (SN-38), an active metabolite of irinotecan (CPT-11), by human UGT1A1 variants, G71R, P229Q, and Y486D
    • Jinno H, Tanaka-Kagawa T, Hanioka N, et al. Glucuro nidation of 7-ethyl-10-hydroxycamptothecin (SN-38), an active metabolite of irinotecan (CPT-11), by human UGT1A1 variants, G71R, P229Q, and Y486D. Drug Metab Dispos 2003; 31: 108-13.
    • (2003) Drug Metab Dispos , vol.31 , pp. 108-113
    • Jinno, H.1    Tanaka-Kagawa, T.2    Hanioka, N.3
  • 24
    • 33744804311 scopus 로고    scopus 로고
    • Comprehensive analysis of UGT1A polymorphisms predictive for pharmacokinetics and treatment outcome in patients with non-small-cell lung cancer treated with irinotecan and cisplatin
    • Han JY, Lim HS, Shin ES, et al. Comprehensive analysis of UGT1A polymorphisms predictive for pharmacokinetics and treatment outcome in patients with non-small-cell lung cancer treated with irinotecan and cisplatin. J Clin Oncol 2006; 24: 2237-44.
    • (2006) J Clin Oncol , vol.24 , pp. 2237-2244
    • Han, J.Y.1    Lim, H.S.2    Shin, E.S.3
  • 25
    • 0344083645 scopus 로고    scopus 로고
    • Haplotype structure of the UDP-glucuronosyltransferase 1A1 (UGT1A1) gene and its relationship to serum total bilirubin concentration in a male Korean population
    • Ki CS, Lee KA, Lee SY, et al. Haplotype structure of the UDP-glucuronosyltransferase 1A1 (UGT1A1) gene and its relationship to serum total bilirubin concentration in a male Korean population. Clin Chem 2003; 49: 2078-81.
    • (2003) Clin Chem , vol.49 , pp. 2078-2081
    • Ki, C.S.1    Lee, K.A.2    Lee, S.Y.3
  • 26
    • 78651097801 scopus 로고    scopus 로고
    • Randomized phase II trial of irinotecan with paclitaxel or gemcitabine for nonsmall cell lung cancer: Association of UGT1A1*6 and UGT1A1*27 with severe neutropenia
    • Nakamura Y, Soda H, Oka M, et al. Randomized phase II trial of irinotecan with paclitaxel or gemcitabine for nonsmall cell lung cancer: Association of UGT1A1*6 and UGT1A1*27 with severe neutropenia. J Thorac Oncol 2010; 6: 121-7.
    • (2010) J Thorac Oncol , vol.6 , pp. 121-127
    • Nakamura, Y.1    Soda, H.2    Oka, M.3
  • 27
    • 0032718482 scopus 로고    scopus 로고
    • Variability at the uridine diphosphate glucuronosyltransferase 1A1 promoter in human populations and primates
    • Hall D, Ybazeta G, Destro-Bisol G, Petzl-Erler ML, Di Rienzo A. Variability at the uridine diphosphate glucuronosyltransferase 1A1 promoter in human populations and primates. Pharmacogenetics 1999; 9: 591-9.
    • (1999) Pharmacogenetics , vol.9 , pp. 591-599
    • Hall, D.1    Ybazeta, G.2    Destro-Bisol, G.3    Petzl-Erler, M.L.4    Di Rienzo, A.5
  • 28
    • 0036498731 scopus 로고    scopus 로고
    • Frequencies of UDP-glucuronosyltransferase 1 (UGT1A1) gene promoter polymorphisms among distinct ethnic groups from Brazil
    • Fertrin KY, Goncalves MS, Saad ST, Costa FF. Frequencies of UDP-glucuronosyltransferase 1 (UGT1A1) gene promoter polymorphisms among distinct ethnic groups from Brazil. Am J Med Genet 2002; 108: 117-9.
    • (2002) Am J Med Genet , vol.108 , pp. 117-119
    • Fertrin, K.Y.1    Goncalves, M.S.2    Saad, S.T.3    Costa, F.F.4
  • 29
    • 0034652640 scopus 로고    scopus 로고
    • Genetic polymorphisms in uridine diphospho-glucuronosyltransferase 1A1 and association with breast cancer among African Americans
    • Guillemette C, Millikan RC, Newman B, Housman DE. Genetic polymorphisms in uridine diphospho-glucuronosyltransferase 1A1 and association with breast cancer among African Americans. Cancer Res 2000; 60: 950-6.
    • (2000) Cancer Res , vol.60 , pp. 950-956
    • Guillemette, C.1    Millikan, R.C.2    Newman, B.3    Housman, D.E.4
  • 30
    • 0036157862 scopus 로고    scopus 로고
    • Genetic polymorphisms of UDP-glucuronosyltransferase in Asians: UGT1A1*28 is a common allele in Indians
    • Balram C, Sabapathy K, Fei G, Khoo KS, Lee EJ. Genetic polymorphisms of UDP-glucuronosyltransferase in Asians: UGT1A1*28 is a common allele in Indians. Pharmacogenetics 2002; 12: 81-3.
    • (2002) Pharmacogenetics , vol.12 , pp. 81-83
    • Balram, C.1    Sabapathy, K.2    Fei, G.3    Khoo, K.S.4    Lee, E.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.